Abstract：
:In electroconvulsive therapy (ECT), remifentanil is often used concurrently with anesthetics. The objective of this study was to provide an up-to-date and comprehensive review on how the addition of remifentanil to anesthetics affects seizure duration and circulatory dynamics in mECT. We performed a meta-analysis of RCTs that investigated seizure duration and circulatory dynamics in patients treated with ECT using anesthetics alone (non-remifentanil group) and with anesthetics plus remifentanil (remifentanil group). A total of 13 RCTs (380 patients and 1024 ECT sessions) were included. The remifentanil group showed a significantly prolonged seizure duration during ECT compared to the non-remifentanil group [motor: 9 studies, SMD = 1.25, 95 % CI (0.21, 2.29), p = 0.02; electroencephalogram: 8 studies, SMD = 0.98, 95 % CI (0.14, 1.82), p = 0.02]. The maximum systolic blood pressure (SBP) was significantly reduced in the remifentanil group compared to the non-remifentanil group [7 studies, SMD = -0.36, 95 % CI (-0.65, 0.07), p = 0.02]. Substantial heterogeneity was observed for meta-analyses for seizure durations, but a pre-planned subgroup analysis revealed that seizure duration was prolonged only when the use of the anesthetic dose was reduced in the remifentanil group. The results of our study suggest that addition of remifentanil to anesthesia in ECT may lead to prolonged seizure duration when it allows the use of reduced anesthetic doses. Further, the addition of remifentanil was associated with reduced maximum SBP.
journal_name
Eur Arch Psychiatry Clin Neurosciauthors
Takekita Y,Suwa T,Sunada N,Kawashima H,Fabbri C,Kato M,Tajika A,Kinoshita T,Furukawa TA,Serretti Adoi
10.1007/s00406-016-0670-0subject
Has Abstractpub_date
2016-12-01 00:00:00pages
703-717issue
8eissn
0940-1334issn
1433-8491pii
10.1007/s00406-016-0670-0journal_volume
266pub_type
杂志文章,meta分析,评审abstract：:Although the Bonn Scale for the Assessment of Basic Symptoms (BSABS) [13] has come into use in several European countries, its diagnostic validity has not yet been sufficiently examined. That is why we have assessed BSABS items on a sample of 243 consecutive admissions to the Department of Psychiatry at the RWTH Unive...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 临床试验,杂志文章
doi：10.1007/BF02189116
更新日期：1996-01-01 00:00:00
abstract：:Besides the ventral tegmental area and the nucleus accumbens as the most investigated brain reward structures, several reports about the relation between volume and activity of the amygdala and drug-seeking behavior have emphasized the central role of the amygdala in the etiology of addiction. Considering its proposed...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-010-0129-7
更新日期：2011-03-01 00:00:00
abstract：:The aim of the study was to examine the psychosis continuum in a Latin-American community setting. Data were from the Brazilian São Paulo Epidemiologic Catchment Area Study, a cross-sectional survey conducted in two boroughs of the city of São Paulo. The Composite International Diagnosis Interview (version 1.1) was ap...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-011-0204-8
更新日期：2011-10-01 00:00:00
abstract：:The excitatory amino acid glutamate plays an important role in the mammalian CNS. Studies conducted from 1940 to 1950 suggested that oral administration of glutamate could have a beneficial effect on normal and retardate intelligence. The neurotoxic nature of glutamate resulting in excitotoxic lesions (neuronal death)...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,评审
doi：10.1007/BF02189982
更新日期：1990-01-01 00:00:00
abstract：:The relationship between lateral ventricular size or its asymmetry and age at the onset of schizophrenia was investigated in 20 schizophrenic patients diagnosed according to DSM-III-R criteria. The ventricle-brain ratio (VBR) was determined using three transaxial slices of magnetic resonance image (MRI) and asymmetry ...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/BF02193086
更新日期：1995-01-01 00:00:00
abstract：:Overactive performance monitoring has been consistently reported in obsessive-compulsive disorder (OCD). OCD is a clinically heterogeneous disorder and is characterized by several symptom dimensions that may have partially distinct neural correlates. We examined whether performance-monitoring alterations are related t...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-014-0499-3
更新日期：2014-12-01 00:00:00
abstract：:Early life maltreatment (ELM) has long-lasting effects on social interaction. When interacting with their own child, women with ELM often report difficulties in parenting and show reduced maternal sensitivity. Sensitive maternal behavior requires the recognition of the child's emotional state depicted in its facial em...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-018-0929-8
更新日期：2019-03-01 00:00:00
abstract：:Some studies suggest seasonality of suicide attempts in females, but not in males. The reasons for this gender difference remain unclear. Only few studies addressed the question whether gender differences in seasonality of suicide attempts reflect gender differences in the choice of method for suicide attempts, with i...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-009-0086-1
更新日期：2010-08-01 00:00:00
abstract：:DTNBP1 is one of the most established susceptibility genes for schizophrenia, and hippocampal volume reduction is one of the major neuropathological findings in this severe disorder. Consistent with these findings, the encoded protein dysbindin-1 has been shown to be diminished in glutamatergic hippocampal neurons in ...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-012-0320-0
更新日期：2013-02-01 00:00:00
abstract：:Alzheimer's disease (AD) is characterized neuropathologically by the presence of amyloid plaques, neuritic plaques, and neurofibrillary tangles (NFTs). These lesions occur not only in demented individuals with AD but also in non-demented persons. In non-demented individuals, amyloid and neuritic plaques are usually ac...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-013-0449-5
更新日期：2013-11-01 00:00:00
abstract：:Altered neuroplasticity contributes to the pathophysiology of schizophrenia. However, the idea that antipsychotics may act, at least in part, by normalizing neurogenesis has not been consistently supported. Our study seeks to determine whether hippocampal cell proliferation is altered in adult rats pretreated with ket...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-009-0033-1
更新日期：2010-03-01 00:00:00
abstract：:The purpose of this article is to encourage research investigating the role of measured gene-environment interaction (G x E) in the etiology of posttraumatic stress disorder (PTSD). PTSD is uniquely suited to the study of G x E as the diagnosis requires exposure to a potentially-traumatic life event. PTSD is also mode...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,评审
doi：10.1007/s00406-007-0787-2
更新日期：2008-03-01 00:00:00
abstract：:The role of the brain-derived neurotrophic factor (BDNF) in the pathophysiology of major depressive disorder (MDD) remains to be elucidated. Recent post hoc analyses indicated a potential association of three polymorphisms in the BDNF gene with worse treatment outcome in patients with the subtype of melancholic depres...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,多中心研究
doi：10.1007/s00406-012-0364-1
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVE:The goal of this study was to identify adverse effects of the atypical neuroleptic clozapine on liver function and lipid metabolism. METHODS:Data which included serum levels of clozapine and its hepatic metabolite N-desmethyl clozapine were collected from medical records of patients treated with clozapine an...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/pl00007544
更新日期：2001-12-01 00:00:00
abstract：:Refsum's disease (Heredopathia atactica polyneuritiformis) is caused by accumulation of phytanic acid in all body tissues due to an inherited failure of alpha-oxidation of branched chain fatty acids. Plasmapheresis has been reported to be beneficial by removal of phytanic acid from the blood. We describe a patient wit...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/BF02191145
更新日期：1991-01-01 00:00:00
abstract：:Impairments in emotion recognition and psychosocial functioning are a robust phenomenon in schizophrenia and may affect motivational behavior, particularly during socio-emotional interactions. To characterize potential deficits and their interplay, we assessed social motivation covering various facets, such as implici...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-015-0589-x
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:This placebo-controlled study was designed to investigate the influence of two different stimulation procedures of repetitive transcranial magnetic stimulation (rTMS) on depressive symptoms in patients with depressive disorders. Furthermore, effects on cognitive functions and psychomotor functioning were tes...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 临床试验,杂志文章
doi：10.1007/s00406-003-0416-7
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND:Only few studies have investigated executive impairment in the euthymic phase of unipolar affective disorders, yielding diverging results. The role of impulsivity/orbitofrontal associated executive functioning in remitted depression has not yet been examined. METHODS:Partly remitted male out-patients (n = 1...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-007-0740-4
更新日期：2007-10-01 00:00:00
abstract：:Depressive disorders are influenced by a complex interplay between genetic and environmental factors. Multiple studies support a role of serotonergic pathways in the pathophysiology of depressive disorders. As a rate-limiting enzyme of serotonin synthesis in the brain, tryptophan hydroxylase 2 (TPH2) represents a plau...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,多中心研究
doi：10.1007/s00406-014-0536-2
更新日期：2014-11-01 00:00:00
abstract：:An international, multicentre, double blind parallel group study compared the tolerability and efficacy of moclobemide with the selective serotonin reuptake inhibitor (SSRI) fluoxetine for panic disorder. SSRIs have been shown effective for panic. The target dose of moclobemide was 450 mg and of fluoxetine was 20 mg. ...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/pl00014164
更新日期：1999-01-01 00:00:00
abstract：:Visually scored and power spectral analyses (PSA) of polysomnography (PSG) recordings reveal abnormalities in alcohol dependence (AD) and major depressive disorder (MDD), including deficiencies in slow wave activity (SWA) during non-rapid eye movement (NREM) sleep. SWA parameters reflect the integrity of the homeostat...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-011-0195-5
更新日期：2011-12-01 00:00:00
abstract：:This paper reports on psychiatric case identification by the application of the Structured Clinical Interview for DSM-III-R (SCID) in a sample of 198 Greek migrants repatriated from western europe in a northwestern province of Greece. The current (1 month) prevalence of psychiatric morbidity, based on the total number...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF02191542
更新日期：1995-01-01 00:00:00
abstract：:A consensus group consisting of 36 experts representing 20 leading German specialist societies and patient self-help organizations developed evidence-based recommendations for the treatment of anxiety disorders in Germany. These were based on a systematic review of randomized controlled trials on anxiety disorders (n ...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,评审
doi：10.1007/s00406-014-0563-z
更新日期：2015-08-01 00:00:00
abstract：:The Cognitive Behavioral Analysis System of Psychotherapy (CBASP) is a relatively new approach in the treatment of chronic depression (CD). Adapted as group psychotherapy for inpatients, CBASP is attracting increasing attention. In this naturalistic multicenter trial, we investigated its feasibility after 10 sessions ...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,多中心研究
doi：10.1007/s00406-017-0843-5
更新日期：2018-12-01 00:00:00
abstract：:Anger is a common and potentially destructive emotion that has considerable social and public health importance. The occurrence of anger, irritability and hostility in depression have been known for many years, but the prevalence, significance for treatment and prognosis and the mechanisms involved remain poorly under...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,评审
doi：10.1007/s00406-004-0539-5
更新日期：2005-08-01 00:00:00
abstract：:Three adult schizophrenic patients without a previous history of epilepsy are reported who, during clozapine treatment, developed paroxysmal EEG patterns and generalized myoclonic jerks without alteration of consciousness. These seizures were phenomenologically identical to those occurring in juvenile myoclonic epilep...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/BF02279769
更新日期：1991-01-01 00:00:00
abstract：:The ability of humans to predict and explain other people's behaviour by attributing independent mental states such as desires and beliefs to them, is considered to be due to our ability to construct a "Theory of Mind". Recently, several neuroimaging studies have implicated the medial frontal lobes as playing a critic...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-006-0676-0
更新日期：2007-02-01 00:00:00
abstract：:Schizophrenia is a severe neuropsychiatric disease that is associated with neurobiological alterations in multiple brain regions and peripheral organs. Negative symptoms and cognitive deficits are present in about half of patients and are difficult to treat, leading to an unfavorable functional outcome. To investigate...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章,评审
doi：10.1007/s00406-019-01025-w
更新日期：2019-08-01 00:00:00
abstract：:This study investigates the nosological specificity and time stability of reduced facial expressivity in schizophrenia by means of objective measurement. Facial expression in an emotional interview was evaluated using the "Facial Action Coding System" in 33 acute schizophrenia patients and 23 acute depressive patients...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 杂志文章
doi：10.1007/s00406-004-0510-5
更新日期：2004-10-01 00:00:00
abstract：:A summarised account is given of Emil Kraepelin's research in the field of mental disorder, underlining his emphasis on objectivity and natural science and the need for a multi-disciplinary approach. At the same time attention is drawn to the limitations of his general outlook and to his political views, which in thei...
journal_title：European archives of psychiatry and clinical neuroscience
pub_type： 传,历史文章,杂志文章
doi：10.1007/BF02191796
更新日期：1995-01-01 00:00:00
