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Deficit of social cognition in subjects with surgically treated frontal lobe lesions and in subjects affected by schizophrenia.

Abstract：

:The ability of humans to predict and explain other people's behaviour by attributing independent mental states such as desires and beliefs to them, is considered to be due to our ability to construct a "Theory of Mind". Recently, several neuroimaging studies have implicated the medial frontal lobes as playing a critical role in a dedicated "mentalizing" or "Theory of Mind" network in the human brain. In this study we compare the performance of patients with right and left medial prefrontal lobe lesions in theory of mind and in social cognition tasks, with the performance of people with schizophrenia. We report a similar social cognitive profile between patients with prefrontal lobe lesions and schizophrenic subjects in terms of understanding of false beliefs, in understanding social situations and in using tactical strategies. These findings are relevant for the functional anatomy of "Theory of Mind".

journal_name

Eur Arch Psychiatry Clin Neurosci

journal_title

European archives of psychiatry and clinical neuroscience

authors

Mazza M,Costagliola C,Di Michele V,Magliani V,Pollice R,Ricci A,Di Giovanbattista E,Roncone R,Casacchia M,Galzio RJ

doi

10.1007/s00406-006-0676-0

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

12-22

issue

1

eissn

0940-1334

issn

1433-8491

journal_volume

257

pub_type

杂志文章

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