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Evidence that mouse astrocytes may be derived from the radial glia. An immunohistochemical study of the cerebellum in the normal and reeler mouse.

Abstract：

:Astrocytic cells of unusual aspect can be detected in the cerebellum of normal mice during the first 4 weeks of life. They are visualized with anti-GFAP (glial fibrillary acidic protein), anti-S100 and anti-vimentin immune sera. Their perikaryons, located in the white matter or in the granular layer, extend long processes which are inserted onto the pial surface. These cells may be transitional forms between the radial glial cells and some of the differentiated astroglial elements. These unusual astrocytes are more numerous and heavily stained in the reeler mutant than in the normal mouse and it is suggested that our observations signify some degree of glial immaturity in the cerebellum of the mutant.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Benjelloun-Touimi S,Jacque CM,Derer P,De Vitry F,Maunoury R,Dupouey P

doi

10.1016/s0165-5728(85)80009-6

subject

Has Abstract

pub_date

1985-07-01 00:00:00

pages

87-97

issue

1-2

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(85)80009-6

journal_volume

9

pub_type

杂志文章

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