Prediction of the DST results in depressives by means of urinary-free cortisol excretion, dexamethasone levels, and age.

abstract：:Five fixed doses of the atypical antipsychotic "Seroquel" (quetiapine) were evaluated to delineate a dose-response relationship, as measured by changes from baseline in Brief Psychiatric Rating Scale (BPRS), Clinical Global Impression (CGI), and Modified Scale for the Assessment of Negative Symptoms (SANS) summary sco...

journal_title：Biological psychiatry

authors： Arvanitis LA,Miller BG

更新日期：1997-08-15 00:00:00

abstract：BACKGROUND:Transcranial magnetic stimulation (TMS) is a noninvasive procedure that may be used to study individual differences in motor cortex excitability. Such differences are assumed to reflect serotonergic and other inputs to the motor cortex. METHODS:Here we investigate the impact of a functional polymorphism in ...

journal_title：Biological psychiatry

authors： Langguth B,Sand P,Marek R,Landgrebe M,Frank E,Hajak G,Eichhammer P

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrate that indirect activation of monoamine receptors by antidepressant treatment increases neurotrophic factors that activate the mitogen-activated protein kinase cascade; however, it is also possible that these monoamine receptors influence the mitogen-activated protein kinase pathwa...

journal_title：Biological psychiatry

authors： Tolbert LM,Russell DS,Duman RS

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:The aim of the present study was to describe the distribution of regional cerebral blood flow during the hypnotic state (HS) in humans, using positron-emission tomography (PET) and statistical parametric mapping. METHODS:The hypnotic state relied on revivification of pleasant autobiographical memories and w...

journal_title：Biological psychiatry

authors： Maquet P,Faymonville ME,Degueldre C,Delfiore G,Franck G,Luxen A,Lamy M

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The interactions among experience, emotion, and memory are considered to be instrumental in the ontogeny and maintenance of acquired emotional and behavioral disorders (e.g., phobias). Here we address the question whether an anxiety-like state can associate with taste to produce conditioned taste aversion (C...

journal_title：Biological psychiatry

authors： Guitton MJ,Dudai Y

更新日期：2004-12-01 00:00:00

abstract：:A group of 759 patients with final DSM-I and -II diagnoses of schizophrenia was identified among a cohort of 1494 adults who were hospitalized between 1965 and 1972. Admission EEG recordings were done in each patient during waking, activation procedures, drowsiness, and sleep. All cases were reclassified according to ...

journal_title：Biological psychiatry

authors： Small JG,Milstein V,Sharpley PH,Klapper M,Small IF

更新日期：1984-04-01 00:00:00

abstract：:A sample of 100 consecutively admitted cases were recruited to test the hypothesis that an abnormal dexamethasone suppression test (AbDST) is associated with decreasing clinical severity during the course of hospitalization in various diagnostic categories. Serial DSTs and psychopathological ratings were done at the e...

journal_title：Biological psychiatry

authors： Hwu HG,Lin HN

更新日期：1990-03-15 00:00:00

abstract：BACKGROUND:Attention-deficit/hyperactivity disorder (ADHD) is the most common psychiatric disorder of childhood, with average worldwide prevalence of 5.3%, varying by region. METHODS:We assessed the relationship between the prevalence of ADHD and solar intensity (SI) (kilowatt hours/square meters/day) on the basis of ...

journal_title：Biological psychiatry

authors： Arns M,van der Heijden KB,Arnold LE,Kenemans JL

更新日期：2013-10-15 00:00:00

abstract：BACKGROUND:Clinical and animal studies suggest that brain serotonergic systems may regulate aggressive behavior; however, the serotonin/violence hypothesis has not been assessed at the epidemiological level. For study of an epidemiological sample we examined blood serotonin, because certain physiological and behavioral...

journal_title：Biological psychiatry

authors： Moffitt TE,Brammer GL,Caspi A,Fawcett JP,Raleigh M,Yuwiler A,Silva P

更新日期：1998-03-15 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) is a stress-related psychiatric disorder that is thought to emerge from complex interactions among traumatic events and multiple genetic factors. Epigenetic regulation lies at the heart of these interactions and mediates the lasting effects of the environment on gene regulation. An...

journal_title：Biological psychiatry

authors： Zannas AS,Provençal N,Binder EB

更新日期：2015-09-01 00:00:00

abstract：:We have investigated the relationship between the concentration of homovanillic acid in human plasma (pHVA) and plasma anti-D1 and anti-D2 dopamine receptor activity in chronic schizophrenic patients whose neuroleptic dosage was changed. The change in pHVA level correlated with that in anti-D1, not anti-D2 activity, t...

journal_title：Biological psychiatry

authors： Suzuki E,Kanba S,Nibuya M,Koshikawa H,Nakaki T,Yagi G

更新日期：1992-02-15 00:00:00

abstract：:An early-onset, familial form of Alzheimer's disease (AD) has been reported to be linked to a locus on the long arm of chromosome 21 (21q21). Furthermore, duplications in the vicinity of this locus involving the beta-amyloid gene and the proto-oncogene ets-2 have been reported in association with AD. The structural ge...

journal_title：Biological psychiatry

authors： Zubenko GS,Sauer P

更新日期：1989-03-15 00:00:00

abstract：:Advances in the understanding of the neurobiology of fear extinction have resulted in the development of d-cycloserine (DCS), a partial glutamatergic N-methyl-D-aspartate agonist, as an augmentation strategy for exposure treatment. We review a decade of research that has focused on the efficacy of DCS for augmenting t...

journal_title：Biological psychiatry

authors： Otto MW,Kredlow MA,Smits JAJ,Hofmann SG,Tolin DF,de Kleine RA,van Minnen A,Evins AE,Pollack MH

更新日期：2016-08-15 00:00:00

abstract：:Elevated plasma vasopressin concentrations have been documented in antipsychotic drug-treated patients as well as a drug-free acutely psychotic patients. To evaluate the effects of antipsychotic drugs on plasma vasopressin, we measured vasopressin response to a single dose of intramuscular chlorpromazine or intravenou...

journal_title：Biological psychiatry

authors： Raskind MA,Courtney N,Murburg MM,Backus FI,Bokan JA,Ries RK,Dorsa DM,Weitzman RE

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:As many as 30% of individuals diagnosed with depression are nonresponsive to traditional antidepressant medication. Augmentation and combination strategies have emerged in an attempt to address this issue. Atypical antipsychotics (e.g., olanzapine), when added to a selective serotonin reuptake inhibitor (e.g...

journal_title：Biological psychiatry

authors： Seager MA,Huff KD,Barth VN,Phebus LA,Rasmussen K

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Brain imaging and behavioral studies suggest an inverse relationship between dopamine (DA) D2/D3 receptors and vulnerability to cocaine abuse, although most research has used males. For example, male monkeys that become dominant in a social group have significant elevations in D2/D3 receptor availability and...

journal_title：Biological psychiatry

authors： Nader MA,Nader SH,Czoty PW,Riddick NV,Gage HD,Gould RW,Blaylock BL,Kaplan JR,Garg PK,Davies HM,Morton D,Garg S,Reboussin BA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Unipolar major depressive disorder (MDD) is characterized by anomalous neurobiological responses to pleasant stimuli, a pattern that may be linked to symptoms of anhedonia. However, the potential for psychotherapy to normalize neurobiological responses to pleasant stimuli has not been evaluated. METHODS:Twe...

journal_title：Biological psychiatry

authors： Dichter GS,Felder JN,Petty C,Bizzell J,Ernst M,Smoski MJ

更新日期：2009-11-01 00:00:00

abstract：:Over the last decade, transcriptome studies of postmortem tissue from subjects with schizophrenia revealed that synaptic, mitochondrial, immune system, gamma-aminobutyric acidergic, and oligodendrocytic changes are all integral parts of the disease process. The combined genetic and transcriptomic studies argue that th...

journal_title：Biological psychiatry

authors： Horváth S,Mirnics K

更新日期：2015-01-01 00:00:00

abstract：:Converging lines of evidence suggest a role for the mesolimbic dopamine system in the response to somatic antidepressant therapies. Here, we review evidence suggesting that antidepressant treatments of different types share the effect of increasing the sensitivity of dopamine D2-like receptors in the nucleus accumbens...

journal_title：Biological psychiatry

authors： Gershon AA,Vishne T,Grunhaus L

更新日期：2007-01-15 00:00:00

abstract：BACKGROUND:Many first-degree relatives of patients with schizophrenia show deficits in clinical, neuropsychological, neurobiological and social domains, in the absence of psychosis. We recently reformulated Meehl's concept of schizotaxia to conceptualize the liability to schizophrenia, and we proposed preliminary crite...

journal_title：Biological psychiatry

authors： Stone WS,Faraone SV,Seidman LJ,Green AI,Wojcik JD,Tsuang MT

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:Pediatric Bipolar Disorder (BD) has been associated with a number of neurocognitive deficits not dissimilar to ADHD. This study compared neuropsychological profiles of 4 groups of adolescents (14-17 years): 41 Normal Controls (NC), 30 ADHD, 12 BD and 12 combined (BD+ADHD). METHODS:Participants were identifi...

journal_title：Biological psychiatry

authors： Rucklidge JJ

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Fragile X syndrome (FXS) is the most common known heritable cause of intellectual disability. Prior studies in FXS have observed a plateau in cognitive and adaptive behavioral development in early adolescence, suggesting that brain development in FXS may diverge from typical development during this period. ...

journal_title：Biological psychiatry

authors： Bray S,Hirt M,Jo B,Hall SS,Lightbody AA,Walter E,Chen K,Patnaik S,Reiss AL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Using diffusion tensor imaging (DTI), we previously reported abnormalities in two critical white matter tracts in schizophrenia, the uncinate fasciculus (UF) and the cingulum bundle (CB), both related to fronto-temporal connectivity. Here, we investigate these two bundles in unmedicated subjects with schizot...

journal_title：Biological psychiatry

authors： Nakamura M,McCarley RW,Kubicki M,Dickey CC,Niznikiewicz MA,Voglmaier MM,Seidman LJ,Maier SE,Westin CF,Kikinis R,Shenton ME

更新日期：2005-09-15 00:00:00

abstract：:We examined the circadian rhythm of core body temperature (CBT) in 22 school refusal patients, ages between 12 and 18 years, who did not have any physical or psychiatric disorders, but had indefinite complaints, and were suspected to have a circadian rhythm disturbance. To obtain normal data for analysis, CBT in 9 hea...

journal_title：Biological psychiatry

authors： Tomoda A,Miike T,Yonamine K,Adachi K,Shiraishi S

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Considering the magnitude of the reported changes in brain volume over time in first-episode patients it is unlikely that these changes are constant over the life-span of the schizophrenic illness. Thus, one would expect the progression in brain volume change in schizophrenia to follow a more complex traject...

journal_title：Biological psychiatry

authors： van Haren NE,Hulshoff Pol HE,Schnack HG,Cahn W,Brans R,Carati I,Rais M,Kahn RS

更新日期：2008-01-01 00:00:00

abstract：:Circling behavior is one of the best understood behaviors in animals. It is, for the most part, dopaminergically mediated and related to asymmetry in dopaminergic activity between the left and right basal ganglia or left and right frontal cortex. As a rule, animals rotate toward the hemisphere with lower striatal dopa...

journal_title：Biological psychiatry

authors： Bracha HS

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Neuregulin-1 (Nrg1) is a pleiotropic signaling molecule that regulates neural development, and mutation of Nrg1 is a risk factor for schizophrenia. Cleavage of type I β1 Nrg1 isoform by Bace1 releases a secreted N-terminal fragment (Nrg1-ntfβ), which can bind to a cognate ErbB receptor to activate the specif...

journal_title：Biological psychiatry

authors： Luo X,He W,Hu X,Yan R

更新日期：2014-07-15 00:00:00

abstract：BACKGROUND:The marker D1S251 of chromosome 1q42.1 showed significant association with schizophrenia in a Taiwanese sample. We used single nucleotide polymorphism (SNP) fine mapping to search for the vulnerability genes of schizophrenia. METHODS:We selected 120 SNPs covering 1 Mb around D1S251 from the public database....

journal_title：Biological psychiatry

authors： Liu YL,Fann CS,Liu CM,Chen WJ,Wu JY,Hung SI,Chen CH,Jou YS,Liu SK,Hwang TJ,Hsieh MH,Ouyang WC,Chan HY,Chen JJ,Yang WC,Lin CY,Lee SF,Hwu HG

更新日期：2006-09-15 00:00:00

abstract：BACKGROUND:To study the influences of drug type and gender on the neuroendocrine response to neuroleptic treatment, we compared the endocrine actions of two neuroleptics with different receptor affinity profiles--a substituted benzamide, amisulpride, a selective D2-like dopamine antagonist; and a thioxanthene, flupenth...

journal_title：Biological psychiatry

authors： Gründer G,Wetzel H,Schlösser R,Anghelescu I,Hillert A,Lange K,Hiemke C,Benkert O

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Norepinephrine and dopamine mediate important aspects of alcoholism and alcohol withdrawal. Dopamine-beta-hydroxylase (DbetaH) converts dopamine to norepinephrine. A recent study demonstrated a strong association between variance in plasma DbetaH activity and a novel polymorphism (DBH-1021C-->T) at the struc...

journal_title：Biological psychiatry

authors： Köhnke MD,Zabetian CP,Anderson GM,Kolb W,Gaertner I,Buchkremer G,Vonthein R,Schick S,Lutz U,Köhnke AM,Cubells JF

更新日期：2002-12-15 00:00:00