Immunoglobulins for intravenous use inhibit TNF alpha cytotoxicity in vitro.

abstract：:Anti-α-galactoside antibody (anti-Gal) from human plasma that bound to α-galactoside-bearing guar galactomannan gel and was eluted with specific sugar (affinity-purified anti-Gal ; APAG) invariably contained apo(a) and apo B subunits in a proportion close to that in plasma lipoprotein(a) [Lp(a)]. Since LDL does not co...

journal_title：Immunological investigations

authors： Mandagini G,Subramanian SP,Vasantha K,Appukuttan PS

更新日期：2013-01-01 00:00:00

abstract：:The bacterial superantigen Staphylococcal enterotoxin-A (SEA), produced by some strains of Staphylococcus aureus, causes proliferation of cytotoxic T-lymphocytes and cytokine production in vivo. SEA has been shown to be highly efficient for antibody-targeted superantegen immunotherapy for different tumor models. A can...

journal_title：Immunological investigations

authors： Mondal TK,Bhatta D,Biswas S,Pal P

更新日期：2002-02-01 00:00:00

abstract：:Many proteins of various origins are able to form complexes with Immunoglobulin G using reaction sites formed by residues of constant domains. Studies of IgG complexes of non-immune nature are important as biologically active proteins could escape from the circulation forming complexes with IgG as well as with other s...

journal_title：Immunological investigations

authors： Nezlin R,Bengtsson AA

更新日期：2008-01-01 00:00:00

abstract：:Plasmodium falciparum CTL epitope minigenes containing HLA-A2 and HLA-B7 subtype supermotifs were cloned into a plasmid expression vector; this expression was measured in eight human HLA class I molecule specific cell lines. Three assays for in vitro antigen presentation analysis were developed to examine the cross-bi...

journal_title：Immunological investigations

authors： Tang Y,Lin Y,Mao Y,Dong M,Wang H

更新日期：2003-02-01 00:00:00

abstract：:The extent of immunological adjuvancy of silicone-gel, from mammary implants, up to now, has not been determined definitively. This study compares the immune potentiation effects of silicone-gel with that of Freund's adjuvant, using bovine serum albumin (BSA) as the test antigen in rats. Sixty, 250 gr., male Sprague D...

journal_title：Immunological investigations

authors： Naim JO,Lanzafame RJ,van Oss CJ

更新日期：1993-03-01 00:00:00

abstract：:Whole-body hyperthermia (WBH) has been used as an adjunct approach to radio-/ chemotherapy for tumor therapy for many years. However, the molecular mechanism underlying the enhancement of tumor control is not clearly understood. It has been hypothesized that WBH might activate immune system by inducing the expression ...

journal_title：Immunological investigations

authors： Zhang H,Wang W,Zhang S,Huang W

更新日期：2005-01-01 00:00:00

abstract：:Cortical (immature) thymocytes are widely reported to express intermediate to high levels of receptors for the lectin, peanut agglutinin (PNA). Light-scatter studies of murine fetal thymocytes stained with PNA or anti-mouse CD4 and CD8 monoclonal antibodies indicated, however, that the most immature CD4-8- (DN) thymoc...

journal_title：Immunological investigations

authors： Holladay S,Blaylock B,Smith B,Luster M

更新日期：1993-12-01 00:00:00

abstract：:Inoculation of metallic tin powder into Lewis rats resulted in marked enlargement of the draining lymph nodes. Plasma cells were the major contributors to the increase in cell mass. Certain immunologic aspects of this plasma cell lymphadenopathy were investigated. Immunoglobulin isotypes were distinguished and quantit...

journal_title：Immunological investigations

authors： Levine S,Saad A,Rappaport I

更新日期：1987-05-01 00:00:00

abstract：:The lectin from Amaranthus leucocarpus (ALL) is specific for N-acetyl-D-galactosamine and inhibits phagocytosis of Leishmania mexicana promastigotes in Balb/c mice peritoneal macrophages by 38%. The lipophosphoglycan (LPG) purified from L. mexicana inhibits penetration of promastigotes into peritoneal macrophages by 3...

journal_title：Immunological investigations

authors： Gorocica P,Hernández P,Perez A,Chávez R,Baez R,Zenteno E,Lascurain R

更新日期：2000-11-01 00:00:00

abstract：:Mast cells have an important role in allergic reactions secreting histamine and other mediators of immediate hypersensitivity. In the present study we evaluated major histocompatibility complex (MHC) class II antigen expression in mast cells and their possible role in antigen presentation. In rats, 10% of mast cells i...

journal_title：Immunological investigations

authors： Banovac K,Neylan D,Leone J,Ghandur-Mnaymneh L,Rabinovitch A

更新日期：1989-08-01 00:00:00

abstract：:The expression of peripheral antigens in the thymus, known as promiscuous gene expression, has been implicated in T cell tolerance and autoimmunity. Here we identified thymic epithelial cells (TECs) as the main cell type that expresses a diverse range of tissue-restricted antigens (TRAs). The TECs of a common autoimmu...

journal_title：Immunological investigations

authors： Chen J,Yang W,Yu C,Li Y

更新日期：2008-01-01 00:00:00

abstract：:The cardinal features of asthma include pulmonary inflammation and airway hyperresponsiveness (AHR). Classically, asthma, specifically allergic asthma, has been attributed to a hyperactive Th2 cell immune response. However, the Th2 cell-mediated inflammation model has failed to adequately explain many of the clinical ...

journal_title：Immunological investigations

authors： Durrant DM,Metzger DW

更新日期：2010-01-01 00:00:00

abstract：:Vitamin D deficiency and vitamin D receptor (VDR) gene polymorphisms have been reported in autoimmune diseases. However, their role in Behçet's disease (BD) and scleroderma remains inconclusive. Our aim was to evaluate vitamin D receptor (ApaI, TaqI) gene polymorphisms in relation to Behçet's disease and scleroderma i...

journal_title：Immunological investigations

authors： Kamal A,Gamal SM,Elgengehy FT,Alkemary AK,Siam I

更新日期：2016-08-01 00:00:00

abstract：:In the present study, we evaluated two novel technologies, the chemiluminescent immunoassay (CIA) QUANTA Flash on BIO-FLASH (Inova Diagnostics, San Diego, CA, USA) and the addressable laser bead immunoassay (ALBIA) on BioPlex™ 2200 (Bio-Rad, Hercules, CA, USA) for the detection of anti-cardiolipin IgG/IgM (aCL) and an...

journal_title：Immunological investigations

authors： Grossi V,Infantino M,Benucci M,Li Gobbi F,Bandinelli F,Damiani A,Bodio C,Borghi MO,Mahler M,Aure MA,Bentow C,Manfredi M

更新日期：2020-02-01 00:00:00

abstract：:It has become apparent that extreme environmental conditions of Antarctic continent alters many immune responses. The present study was conducted on 28th Indian Antarctic expeditioners. The investigations were carried out to explore the effect of multiple stresses like isolation, cold and UV exposure on human immunity...

journal_title：Immunological investigations

authors： Mishra KP,Yadav AP,Shweta,Chanda S,Ganju L,Majumdar D,Ilavazhagan G

更新日期：2010-01-01 00:00:00

abstract：:Alveolar macrophages (AM) freshly obtained by bronchoalveolar lavage suppressed significantly, in a dose-dependent fashion, lung interstitial lymphocytes cytotoxicity against the NK-sensitive target cells, YAC-1. Kinetic experiments revealed that AM-mediated suppression of NK activity was seen following short-term inc...

journal_title：Immunological investigations

authors： Lemaire I,St-Jean M

更新日期：1990-02-01 00:00:00

abstract：:Monocyte chemoattractant protein 1 (MCP-1) plays an important role in the development of periodontitis. The purpose of this investigation was to evaluate association of the  MCP-1 gene polymorphism with chronic periodontitis in patients with end-stage renal disease (ESRD). One hundred fifty ESRD patients with chronic ...

journal_title：Immunological investigations

authors： Ksiazek K,Buraczynska M

更新日期：2020-11-01 00:00:00

abstract：:Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder caused by genetic, environmental and immunological factors. It is known that neural development processes are affected by immune functions. The aim of this study is to evaluate the relationship between cytokines IL6 and IL1B gene polymorphisms...

journal_title：Immunological investigations

authors： Pekkoc Uyanik KC,Kalayci Yigin A,Dogangun B,Seven M

更新日期：2021-01-12 00:00:00

abstract：:Hematological disorders like Aplastic anemia are quite frequent in Pakistan. Human leukocyte antigen (HLA) system, have been implicated in the development of Aplastic anemia in various population-based studies, The aim of this study was to determine the role of the HLA Class I and Class II alleles in genetic susceptib...

journal_title：Immunological investigations

authors： Rehman S,Saba N,Khalilullah,Munir S,Ahmed P,Mehmood T

更新日期：2009-01-01 00:00:00

abstract：:Corneal transplant is the most common solid tissue transplant in humans. Advances in microsurgical techniques, eye banking and the use of corticosteroids have improved the success of corneal transplants. Over 65,000 corneal transplants are being performed worldwide annually. Most of these transplants are performed in ...

journal_title：Immunological investigations

authors： Kumar V,Kumar A

更新日期：2014-01-01 00:00:00

abstract：:In a previous study, we noticed that some ascitic cells isolated from melanoma patients survive, proliferate, and differentiate into giant phagocytes after the other cells died. Similar phenomena were observed in the primary cultures of mouse lung and liver cells. In the present study, the effects of dying cells on ab...

journal_title：Immunological investigations

authors： Yuan X,Li X,Zhang Q,Zhang C,Yang Z,Li D

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to evaluate the possible association of IL12B gene polymorphisms with serum levels of IL-12p40, IL-23 and genetic susceptibility to rheumatoid arthritis (RA) in the Bulgarian population. Genotyping for IL12Bpro (rs17860508) and IL12B A/C - 3' UTR (rs3212227) polymorphisms was performed by pol...

journal_title：Immunological investigations

authors： Manolova I,Ivanova M,Vasilev G,Stoilov R,Miteva L,Stanilova S

更新日期：2020-02-01 00:00:00

abstract：:Although the T cell costimulatory molecules CD2 and CD28 are enriched within the immunological synapse (IS), it has been suggested that costimulatory molecules need not be localized to the contact site between a T cell and an antigen-presenting cell (APC) in order to costimulate T cell activation. To determine whether...

journal_title：Immunological investigations

authors： Watson CL,Furlong SJ,Hoskin DW

更新日期：2008-01-01 00:00:00

abstract：:As a result of strong experimental data supporting effectiveness and safety, herb-based immunomodulators are paving way as alternative sources of potent adjuvants for vaccines. In this study, the immunostimulatory and adjuvant properties of AcF1, a flavonoids-rich fraction of Alchornea cordifolia extract, was evaluate...

journal_title：Immunological investigations

authors： Nworu CS,Esimone CO,Tenbusch M,Nabi G,Proksch P,Uberla K,Temchura VV

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The pathological mechanisms associated with the occurrence and development of Behcet's disease (BD) are not yet known. Two large genome-wide association surveys revealed an association between interleukin (IL)-23R single nucleotide polymorphism and BD. This study aimed to investigate the association between ...

journal_title：Immunological investigations

authors： Gong HB,Wu XJ,Pu XM,Kang XJ

更新日期：2020-08-01 00:00:00

abstract：:The relationship between antibody avidity, measured by the dissociation of the antigen-antibody bond in antigen excess, and antibody affinity was studied. Complexes of radiolabelled antigen and antibody of known affinity were prepared in vitro and allowed to stand for seven days to reach equilibrium. Then nonlabelled ...

journal_title：Immunological investigations

authors： Griswold WR

更新日期：1987-04-01 00:00:00

abstract：:The susceptibility of cataract Shionogi (CTS) mice as young as 8 to 10 weeks of age to passive anaphylactic shock mediated by anti-benzylpenicilloyl IgE and IgG1 monoclonal antibodies was compared with those of other strains of the same age including sister strains such as nonobese-diabetic (NOD) and nonobese-nondiabe...

journal_title：Immunological investigations

authors： Harada M,Nagata M,Takeuchi M,Makino S,Aburahi S

更新日期：1991-06-01 00:00:00

abstract：:We report a method combining mixed lymphocyte reaction (MLR) using a carboxyfluorescein diacetate succinimidyl ester (CFSE)-labeling technique, intracellular cytokine immunofluorescence staining (ICIS), and multiparameter flow cytometry for simultaneous determination of proliferation and cytokine-secreting activity in...

journal_title：Immunological investigations

authors： Tanaka Y,Ohdan H,Onoe T,Asahara T

更新日期：2004-08-01 00:00:00

abstract：:Competitive binding to polystyrene-bound antigens showed that human rye Group I (rye I)-specific IgG recognize the same three distinct epitopes of rye I as three monoclonal antibodies directed against the same antigens. Anti-idiotypic antibodies against one of the monoclonal antibodies (290A-167) inhibit completely th...

journal_title：Immunological investigations

authors： Mourad W,Hébert J

更新日期：1986-12-01 00:00:00

abstract：:An enzyme-linked immunoassay (EIA) is described and evaluated which quantitates human antibodies to serotype specific S. pneumoniae polysaccharide (PnPs) in human sera. Based on the observations previously described by Koskela (1), native PnPs are used as coating antigens and sera are absorbed with a soluble pneumococ...

journal_title：Immunological investigations

authors： Quataert S,Martin D,Anderson P,Giebink GS,Henrichsen J,Leinonen M,Granoff DM,Russell H,Siber G,Faden H,Barnes D,Madore DV

更新日期：2001-08-01 00:00:00