Human plasma anti-α-galactoside antibody forms immune complex with autologous lipoprotein(a).

abstract：:Previous work had implicated T cells within the stimulating population as having a significant role in the MLR. We now report that depletion of T cells from the stimulators caused a reduction in proliferative response in mixed leukocyte reaction (MLR) by 50% or more. This response could be restored by adding T-enriche...

journal_title：Immunological investigations

authors： Roy C,Brown DL,Kaplan JG

更新日期：1986-03-01 00:00:00

abstract：:Anti-galactocerebroside (GalC) antibodies have been reported to inhibit myelin formation, cause demyelination, and block HIV-I infection of neural cells. We examined the binding of 3 monoclonal and polyclonal anti-GalC antibodies to a panel of purified glycolipids by ELISA and by an immunospot assay on nitrocellulose ...

journal_title：Immunological investigations

authors： McAlarney T,Ogino M,Apostolski S,Latov N

更新日期：1995-05-01 00:00:00

abstract：:DNA vaccine represents a powerful approach for prevention of avian H5N1 influenza infection. Yet, DNA vaccine-induced immune responses might be limited by the short duration of antigen expression. As a strategy to enhance adaptive immune responses elicited by a hemagglutinin 5 (H5) DNA vaccine, we explored the effect ...

journal_title：Immunological investigations

authors： Tabatabaeizadeh SE,Bassami MR,Haghparast A,Dehghani H

更新日期：2015-01-01 00:00:00

abstract：:Regulatory T cells (Tregs) play pivotal roles in limiting the duration and magnitude of immune response against infectious agents and self-antigens. This is accomplished through contact-dependent and -independent mechanisms that involve crosstalk between Treg cells and other immune and tissue-specific cell types. The ...

journal_title：Immunological investigations

authors： Wang K,Vella AT

更新日期：2016-11-01 00:00:00

abstract：:A single-nucleotide polymorphism in the promoter region of the CD14 gene at position 159 has been implicated in susceptibility to infectious diseases. We sought to determine the association between CD14 C-159 T functional promoter polymorphism and brucellosis in Western Iranian population where the disease is endemic....

journal_title：Immunological investigations

authors： Haidari M,Hajilooi M,Rezazadeh M,Rafiei A,Alavi SA,Keramat F

更新日期：2006-01-01 00:00:00

abstract：:Intravenous immunoglobulins (IVIg) have been used as an immunomodulatory therapy in a variety of diseases. Several mechanisms of action have been proposed, one of which is interference with the cytokine network. We have investigated the effect of IVIg on the cytotoxicity of human TNF alpha. IVIg was capable of protect...

journal_title：Immunological investigations

authors： Stangel M,Schumacher HC,Ruprecht K,Boegner F,Marx P

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae is a major pathogen accounting for a large number of pneumococcal disease in worldwide. Due to the mucosal immune pathway induces both systemic and mucosal immune responses, the potential strategy to prevent pneumococcal disease may be to develop a mucosal vaccine. METHOD:In this st...

journal_title：Immunological investigations

authors： Wang D,Lu J,Yu J,Hou H,Leenhouts K,Van Roosmalen ML,Gu T,Jiang C,Kong W,Wu Y

更新日期：2018-05-01 00:00:00

abstract：:Exposure to laboratory animals poses a hazard for development of occupational allergy. Identification of antigenic determinants of allergenic proteins may be valuable for immunotherapeutic purposes. Overlapping peptides of the major allergen in rat urine, Rat n 1.02, corresponding to the protein alpha2u-globulin were ...

journal_title：Immunological investigations

authors： Bayard C,Siddique AB,Berzins K,Troye-Blomberg M,Hellman U,Vesterberg O

更新日期：1999-09-01 00:00:00

abstract：:The induction of immune tolerance is the most common consequence of protein feeding, i.e., "oral tolerance". In this study we investigated the genetic basis of oral tolerance using various kinds of recombinant and congenic mice, and the cells involved in the development of this phenomenon in mice. The footpad swelling...

journal_title：Immunological investigations

authors： Ishii N,Moriguchi N,Sugita Y,Nakajima H,Tanaka S,Aoki I

更新日期：1993-08-01 00:00:00

abstract：:Objectives: Type 1 diabetes mellitus (T1D) has been disclosed to be associated with an elevated risk of cardiovascular disease (CVD), as well as increased risks of losing bone mass and progression of osteoporosis (OP). Osteoprotegerin (OPG), as a decoy receptor, has been demonstrated to play a critical role in bone me...

journal_title：Immunological investigations

authors： Duan CC,Ma C,Tang HQ

更新日期：2021-02-01 00:00:00

abstract：:Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder caused by genetic, environmental and immunological factors. It is known that neural development processes are affected by immune functions. The aim of this study is to evaluate the relationship between cytokines IL6 and IL1B gene polymorphisms...

journal_title：Immunological investigations

authors： Pekkoc Uyanik KC,Kalayci Yigin A,Dogangun B,Seven M

更新日期：2021-01-12 00:00:00

abstract：:IL-2 production by the phytohemaglutinin (PHA)-stimulated mononuclear cells (MNC) of peripheral blood (PB) and synovial fluid (SF) from patients with rheumatoid arthritis (RA), other arthritic diseases (OAD) and age-matched normal controls were studied, and the activity of IL-2 inhibitor in sera of studied subject was...

journal_title：Immunological investigations

authors： Wu CH,Jeng KC,Lan JL

更新日期：1995-11-01 00:00:00

abstract：:The bacterial superantigen Staphylococcal enterotoxin-A (SEA), produced by some strains of Staphylococcus aureus, causes proliferation of cytotoxic T-lymphocytes and cytokine production in vivo. SEA has been shown to be highly efficient for antibody-targeted superantegen immunotherapy for different tumor models. A can...

journal_title：Immunological investigations

authors： Mondal TK,Bhatta D,Biswas S,Pal P

更新日期：2002-02-01 00:00:00

abstract：:The extent of immunological adjuvancy of silicone-gel, from mammary implants, up to now, has not been determined definitively. This study compares the immune potentiation effects of silicone-gel with that of Freund's adjuvant, using bovine serum albumin (BSA) as the test antigen in rats. Sixty, 250 gr., male Sprague D...

journal_title：Immunological investigations

authors： Naim JO,Lanzafame RJ,van Oss CJ

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:IL-23/Th17 signaling pathway plays a crucial role in the cell-mediated immune response against bacterial infections and also in the pathogenesis of inflammatory and autoimmune diseases. Recent studies indicate that Th17 cell-associated cytokines are involved in the progression and maintenance of valvular les...

journal_title：Immunological investigations

authors： Poomarimuthu M,Elango S,Solomon PR,Soundrapandian S,Mariakuttikan J

更新日期：2018-10-01 00:00:00

abstract：:VH4-34 gene encoded autoantibodies are elevated in systemic lupus erythematosus (SLE) and in other diseases associated with B-cell hyperproliferation/dysfunction. One of the autoantigens recognized by VH4-34-encoded antibodies are branched/linear poly N-acetyl lactosamine chains. Since the anti-carbohydrate response i...

journal_title：Immunological investigations

authors： Bhat NM,Kshirsagar MA,Bieber MM,Teng NN

更新日期：2015-01-01 00:00:00

abstract：:In this study, we aimed to explore the association among gene variants of five cytokines, tumor necrosis factor alpha (TNF-α), transforming growth factor beta-1 (TGF-β1), interferon gamma (IFN-γ), interleukin-6 (IL-6), and interleukin-10 (IL-10), and clinical parameters and prognosis in patients with multiple myeloma ...

journal_title：Immunological investigations

authors： Haydaroglu H,Oguzkan Balcı S,Pehlıvan S,Ozdıllı K,Gundogan E,Okan V,Nursal AF,Pehlıvan M

更新日期：2017-01-01 00:00:00

abstract：:The cardinal features of asthma include pulmonary inflammation and airway hyperresponsiveness (AHR). Classically, asthma, specifically allergic asthma, has been attributed to a hyperactive Th2 cell immune response. However, the Th2 cell-mediated inflammation model has failed to adequately explain many of the clinical ...

journal_title：Immunological investigations

authors： Durrant DM,Metzger DW

更新日期：2010-01-01 00:00:00

abstract：:The role of ICAM-1 in contact activation of the bronchial epithelial cells is elucidated. Direct contact between epithelial cells and leukocytes is required to change transepithelial electrical resistance (TER) of the epithelium. Migration of human neutrophils across the layers of cultured human airway epithelial cell...

journal_title：Immunological investigations

authors： Choi H,Fleming NW,Serikov VB

更新日期：2007-01-01 00:00:00

abstract：:Interleukin-31 (IL-31) has diverse biological functions. Increased IL-31 has been found in some skin and autoimmune diseases. There has been no study reporting the association between IL-31 and primary biliary cholangitis (PBC). This study was designed to determine serum IL-31 level and to explore its diagnostic value...

journal_title：Immunological investigations

authors： Mu N,Lin F,Jiang Z,Liang Y,Yang Z

更新日期：2020-07-02 00:00:00

abstract：:Results of recent studies indicated that a monoclonal ART18 antibody recognizes the receptor sites or closely related structures for IL-2 on activated rat T-cells. The major histocompatibility complex (MHC) class II (Ia) antigens (RT1B and RT1D in rat), detected with OX6 antibody, and OX17 antibody, may be present on ...

journal_title：Immunological investigations

authors： Chan CC,Caspi R,Mochizuki M,Diamantstein T,Gery I,Nussenblatt RB

更新日期：1987-06-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) is a dietary fatty acid which causes extensive remodeling and mast cell recruitment in the mouse mammary gland. Two CLA isomers, 9,11- and 10,12-CLA, have differing effects in vivo, with only 10,12-CLA increasing mast cell number. The purpose of this project is to test the hypothesis tha...

journal_title：Immunological investigations

authors： Krishnan S,Russell J,Bodziak M,Koury S,Masso-Welch P

更新日期：2012-01-01 00:00:00

abstract：:The purpose of this presentation was to demonstrate that the red blood cell is not a hapless sac of hemoglobin and that much research is still needed for better understanding of its complexities. After a brief historical introduction the following subjects are presented: 1). Phosphofructokinase is the rate limiting st...

journal_title：Immunological investigations

authors： Greenwalt TJ

更新日期：1995-01-01 00:00:00

abstract：:Electron microscopy (EM) is a valuable tool in diagnostic medicine, and in some cases, can be enhanced by immunological methods. A major medical application of EM, diagnostic virology, can frequently be augmented by employment of immunological reagents. Three immunoelectron microscopy (IEM) methods, aggregation, coati...

journal_title：Immunological investigations

authors： Miller SE,Howell DN

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:This study determined whether tumor necrosis factor alpha (TNF-α) and Interleukin-10 (IL-10) polymorphisms are associated with susceptibility to dengue. METHODS:a systematic review with meta-analysis was conducted of the associations between the TNF-α (-308G/A) and IL-10 (-819C/T) polymorphisms and dengue. ...

journal_title：Immunological investigations

authors： Santos AC,de Moura EL,Ferreira JM,Santos BR,Alves VM,de Farias KF,de Souza Figueiredo EV

更新日期：2017-02-01 00:00:00

abstract：:The objectives were to determine the prevalence and clinical significance of anti-cyclic citrullinated peptide (anti-CCP) antibodies in patients with juvenile idiopathic arthritis (JIA). Anti-CCP antibodies were checked by ELISA in 68 children with JIA, 38 males and 30 females with mean age of 10.6 (+/-4.02) years and...

journal_title：Immunological investigations

authors： Habib HM,Mosaad YM,Youssef HM

更新日期：2008-01-01 00:00:00

abstract：:Thrombocytopenia as a complicating event in human immunodeficiency infection is a rather common hematological disorder and in many aspects resembles idiopathic(immune) thrombocytopenic purpura (ITP). Consequently, treatment of severe cases is similar to treating ITP, but steroids should be administered with particular...

journal_title：Immunological investigations

authors： Nydegger UE,Castelli D

更新日期：1991-04-01 00:00:00

abstract：:In a previous study, we noticed that some ascitic cells isolated from melanoma patients survive, proliferate, and differentiate into giant phagocytes after the other cells died. Similar phenomena were observed in the primary cultures of mouse lung and liver cells. In the present study, the effects of dying cells on ab...

journal_title：Immunological investigations

authors： Yuan X,Li X,Zhang Q,Zhang C,Yang Z,Li D

更新日期：2013-01-01 00:00:00

abstract：:Plasmin activity induced by different concentrations of added urokinase (UK) in serum from 20 patients with AIDS (P) and 10 healthy control (HC) subjects was measured using the fibrin plate assay. 125I-fibrin coated 24 well plates were exposed to UK (0.34-6.8 ng/ml) or to trypsin (T) (2.5 micrograms/ml) in the presenc...

journal_title：Immunological investigations

authors： Auci DL,Durkin HG,Murali MR

更新日期：1992-07-01 00:00:00

abstract：:Studies demonstrated that deficiency in 17β-estradiol (E2) in postmenopausal women influences their immune system. However, few studies have reported alterations in immunologic presentation during nonnatural menopause in young females. Here we compared the differences in immune response between young C57BL/6N mice wit...

journal_title：Immunological investigations

authors： Shao MJ,Zhu YJ,Qiu YE,Hu M,He YQ

更新日期：2017-04-01 00:00:00