Contact activation via ICAM-1 induces changes in airway epithelial permeability in vitro.

abstract：:Peripheral blood lymphocytes of a patient with myasthenia gravis (MG) were fused to the non-secreting human lymphoblastoid line HuNSI to produce human x human hybridomas that secrete monoclonal antibodies (mAb) to acetylcholine receptor (AChR). Screening of hybridomas for antibody production involved an enzyme-linked ...

journal_title：Immunological investigations

authors： Blair DA,Richman DP,Taves CJ,Koethe S

更新日期：1986-06-01 00:00:00

abstract：:Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder caused by genetic, environmental and immunological factors. It is known that neural development processes are affected by immune functions. The aim of this study is to evaluate the relationship between cytokines IL6 and IL1B gene polymorphisms...

journal_title：Immunological investigations

authors： Pekkoc Uyanik KC,Kalayci Yigin A,Dogangun B,Seven M

更新日期：2021-01-12 00:00:00

abstract：:The aim of this study was to evaluate the possible association of IL12B gene polymorphisms with serum levels of IL-12p40, IL-23 and genetic susceptibility to rheumatoid arthritis (RA) in the Bulgarian population. Genotyping for IL12Bpro (rs17860508) and IL12B A/C - 3' UTR (rs3212227) polymorphisms was performed by pol...

journal_title：Immunological investigations

authors： Manolova I,Ivanova M,Vasilev G,Stoilov R,Miteva L,Stanilova S

更新日期：2020-02-01 00:00:00

abstract：:We tested by Western blot several thousand antibody-secreting human cell lines immortalized by hybridoma fusion or Epstein-Barr virus transformation of peripheral blood lymphocytes from patients with systemic lupus erythematosus or mixed connective tissue disease. The blots utilized total human Jurkat cell extract as ...

journal_title：Immunological investigations

authors： Vanderslice WE,Takeda Y,Chen J,Sharp GC,Pettersson I,Rosen A,Wigzell H,Wang RJ

更新日期：1988-06-01 00:00:00

abstract：:We examined the effect of various polyanions on mouse complement hemolytic activity, Fc receptor (FcR) subclass mediated antibody-dependent cellular cytotoxicity (ADCC) as well as binding by mouse peritoneal macrophages (M phi) of sheep erythrocyte targets. All the polyanions tested (dextran sulfate, carrageenan, poly...

journal_title：Immunological investigations

authors： Mocharla R,Mocharla H,Leu RW

更新日期：1989-06-01 00:00:00

abstract：:In this study, we aimed to explore the association among gene variants of five cytokines, tumor necrosis factor alpha (TNF-α), transforming growth factor beta-1 (TGF-β1), interferon gamma (IFN-γ), interleukin-6 (IL-6), and interleukin-10 (IL-10), and clinical parameters and prognosis in patients with multiple myeloma ...

journal_title：Immunological investigations

authors： Haydaroglu H,Oguzkan Balcı S,Pehlıvan S,Ozdıllı K,Gundogan E,Okan V,Nursal AF,Pehlıvan M

更新日期：2017-01-01 00:00:00

abstract：:CD44 comprises a family of type I transmembrane glycoproteins that is expressed on a wide range of cells including those of epithelial, lymphoid and myeloid lineage. Although expression of CD44 in the small intestine is typically localised in the crypts of Lieberkuhn, we have reported the expression of CD44 on mature,...

journal_title：Immunological investigations

authors： Reid SD,Pockley AG

更新日期：2000-08-01 00:00:00

abstract：:Woodchucks infected with woodchuck hepatitis virus (WHV) represent the closest natural animal model to study the immunopathogenesis of liver injury caused by essentially noncytopathic, highly human specific hepatitis B virus (HBV). The importance of antiviral T cell response in induction of hepatitis and in control of...

journal_title：Immunological investigations

authors： Gujar SA,Michalak TI

更新日期：2005-01-01 00:00:00

abstract：:A rapid, quantitative enzyme-linked immunosorbent assay (ELISA) for the immunodiagnosis of Chagas' disease is described. The ELISA was standardized with the Falcon assay screening test (F.A.S.T.) system using a purified Trypanosoma cruzi epimastigote fraction (PEF) obtained by ion exchange chromatography. The ELISA te...

journal_title：Immunological investigations

authors： Partel CD,Rossi CL

更新日期：1998-01-01 00:00:00

abstract：:Jeevaneeya rasayana is an ayurvedic polyherbal formulation, with antirheumatic potential. The present study investigates the therapeutic efficacy of isolated total alkaloid fraction of Jeevaneeya Rasayana (AJR) in treating rheumatoid arthritis in a rat model of Adjuvant-induced arthritis (AIA). Paw swelling, inflammat...

journal_title：Immunological investigations

authors： Shyni GL,Sindhu G,Helen A

更新日期：2015-01-01 00:00:00

abstract：:The expression of peripheral antigens in the thymus, known as promiscuous gene expression, has been implicated in T cell tolerance and autoimmunity. Here we identified thymic epithelial cells (TECs) as the main cell type that expresses a diverse range of tissue-restricted antigens (TRAs). The TECs of a common autoimmu...

journal_title：Immunological investigations

authors： Chen J,Yang W,Yu C,Li Y

更新日期：2008-01-01 00:00:00

abstract：:A. actinomycetemcomitans is a facultative Gram-negative coccobacillus which has been implicated in the etiology and pathogenesis of localized juvenile periodontitis and has also been recognized for its potential to cause serious extraoral infections, particularly endocarditis. The polymorphonuclear neutrophil has been...

journal_title：Immunological investigations

authors： Wilson ME,Genco RJ

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:This study aimed to examine the association of three functional IRF5 rs10954213, rs3757385, and rs41298401 polymorphisms with susceptibility to unexplained recurrent pregnancy loss (RPL) among Iranian women from south of Iran. METHODS:176 women with unexplained RPL and 173 healthy postmenopausal controls wer...

journal_title：Immunological investigations

authors： Amiri Jahromi R,Nasiri M,Jahromi AR

更新日期：2017-01-01 00:00:00

abstract：:Very little is known about the effects of acute psychological stress on the production of reactive oxygen species (ROS) by human phagocytic cells and the interplay between subjectively perceived stress, mediating hormones, variations in the number of peripheral leukocytes and ROS production. We measured psychological ...

journal_title：Immunological investigations

authors： Atanackovic D,Brunner-Weinzierl MC,Kröger H,Serke S,Deter HC

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are the potential modulators of inflammatory reactions that exert several unique biological effects and could lead to future adverse events of coronary artery disease (CAD). HYPOTHESIS:The purpose of this study was to find out the possible association of modulation in NK cell, TNK ...

journal_title：Immunological investigations

authors： Jabir NR,Firoz CK,Ahmed F,Kamal MA,Hindawi S,Damanhouri GA,Almehdar HA,Tabrez S

更新日期：2017-07-01 00:00:00

abstract：:The induction of immune tolerance is the most common consequence of protein feeding, i.e., "oral tolerance". In this study we investigated the genetic basis of oral tolerance using various kinds of recombinant and congenic mice, and the cells involved in the development of this phenomenon in mice. The footpad swelling...

journal_title：Immunological investigations

authors： Ishii N,Moriguchi N,Sugita Y,Nakajima H,Tanaka S,Aoki I

更新日期：1993-08-01 00:00:00

abstract：:In order to characterize the immune response to BK virus, a human polyomavirus containing dsDNA and host cell histones, we followed the appearance of antibodies in five outbred rabbits after intravenous inoculation with purified infectious BK virus without any adjuvant. The animals were followed for 15 weeks after the...

journal_title：Immunological investigations

authors： Fredriksen K,Traavik T,Flaegstad T,Rekvig OP

更新日期：1990-04-01 00:00:00

abstract：:Adjuvant interleukin (IL)-2 immunotherapy has been used in the treatment of different malignant dieseases. However, clinical results have been rather disappointing. Therefore, further investigations on IL-2-induced mediators of cytotoxicity seem to be necessary in order to possibly create cytokine cocktails which coul...

journal_title：Immunological investigations

authors： Mauz-Körholz C,Banning U,Körholz D

更新日期：2004-05-01 00:00:00

abstract：:The cardinal features of asthma include pulmonary inflammation and airway hyperresponsiveness (AHR). Classically, asthma, specifically allergic asthma, has been attributed to a hyperactive Th2 cell immune response. However, the Th2 cell-mediated inflammation model has failed to adequately explain many of the clinical ...

journal_title：Immunological investigations

authors： Durrant DM,Metzger DW

更新日期：2010-01-01 00:00:00

abstract：:The objective of this study was to analyze how Staphylococcus epidermidis SCV and WT strains manipulate the PI3K/Akt/mTOR signaling pathway. Six S. epidermidis strains with normal phenotype (WT) and six S. epidermidis strains with SCV phenotype were isolated in parallel from six patients with the prosthetic hip joint ...

journal_title：Immunological investigations

authors： Magryś A,Bogut A,Kiełbus M,Olender A

更新日期：2018-04-01 00:00:00

abstract：:Major histocompatibility complex (MHC) restriction of antigen presentation of a single mucin1 (MUC1) variable number of tandem repeats peptide (VNTR1) was examined by generating cytotoxic T lymphocytes (CTL) derived from peripheral blood mononuclear cells (PBMC) stimulated with a single repeat MUC1 peptide presented b...

journal_title：Immunological investigations

authors： Orr MK,Burnside JS,Phillips CA,Philip R,Dombrowski KE,Wright SE

更新日期：2007-01-01 00:00:00

abstract：:Uric acid can be generated in the gastrointestinal (GI) tract from the breakdown of nucleotides ingested in the diet or from purines released from host cells as a result of pathogen-induced cell damage. Xanthine oxidase (XO) is the enzyme that converts hypoxanthine or xanthine into uric acid, a reaction that also gene...

journal_title：Immunological investigations

authors： Crane JK,Mongiardo KM

更新日期：2014-01-01 00:00:00

abstract：:In recent studies, using a swine model of single lung transplantation, we demonstrated that IRI alone increased MHC II expression in the host's peripheral T lymphocytes. The inhibition of increased MHC II expression with TCV-309, a specific platelet-activating factor (PAF) antagonist suggested that PAF might play a ro...

journal_title：Immunological investigations

authors： Nikbakht-Sangari M,Qayumi AK,Keown P,Duronio V,Horley K

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:This study determined whether tumor necrosis factor alpha (TNF-α) and Interleukin-10 (IL-10) polymorphisms are associated with susceptibility to dengue. METHODS:a systematic review with meta-analysis was conducted of the associations between the TNF-α (-308G/A) and IL-10 (-819C/T) polymorphisms and dengue. ...

journal_title：Immunological investigations

authors： Santos AC,de Moura EL,Ferreira JM,Santos BR,Alves VM,de Farias KF,de Souza Figueiredo EV

更新日期：2017-02-01 00:00:00

abstract：:The complement system which is a critical mediator of innate immunity plays diverse roles in the neuropathogenesis of HIV-1 infection such as clearing HIV-1 and promoting productive HIV-1 replication. In the development of HIV-1 associated neurological disorders (HAND), there may be an imbalance between complement act...

journal_title：Immunological investigations

authors： Mahajan SD,Aalinkeel R,Parikh NU,Jacob A,Cwiklinski K,Sandhu P,Le K,Loftus AW,Schwartz SA,Quigg RJ,Alexander JJ

更新日期：2017-11-01 00:00:00

abstract：:Dendritic cells (DCs) are potent antigen-presenting cells that can be matured in vitro from immature dendritic cells (iDCs) in the presence of several biological agents such as cytokine cocktail, CD40L, TNF-a and antigen loading, which are necessary and achieved using various protocols, such as lipofection, passive pu...

journal_title：Immunological investigations

authors： Son CH,Bae JH,Shin DY,Lee HR,Choi YH,Yang K,Park YS

更新日期：2013-01-01 00:00:00

abstract：:Hashimoto's thyroiditis (HT) is a T cell-mediated autoimmune disease. However, little is known about the role of different subsets of natural killer (NK) and natural killer T (NKT) cells at the early stage of the HT process. A total of 45 euthyroid patients with new onset HT and 40 age/gender-matched healthy controls ...

journal_title：Immunological investigations

authors： Guo H,Xu B,Yang X,Wang Y,Liu X,Cui C,Jiang Y

更新日期：2014-01-01 00:00:00

abstract：:Competitive binding to polystyrene-bound antigens showed that human rye Group I (rye I)-specific IgG recognize the same three distinct epitopes of rye I as three monoclonal antibodies directed against the same antigens. Anti-idiotypic antibodies against one of the monoclonal antibodies (290A-167) inhibit completely th...

journal_title：Immunological investigations

authors： Mourad W,Hébert J

更新日期：1986-12-01 00:00:00

abstract：:Many investigators have demonstrated alteration of gastric mucins in H. pylori infected individuals. The inflammatory environment induced by H. pylori leading to aberrant glycosylation of MUC1 and demasking of core peptide MUC1 epitope could enhance immune responses to MUC1. IgG and IgM immune response to MUC1 in pati...

journal_title：Immunological investigations

authors： Klaamas K,Kurtenkov O,von Mensdorff-Pouilly S,Shljapnikova L,Miljukhina L,Brjalin V,Lipping A

更新日期：2007-01-01 00:00:00

abstract：:Endomyocardial biopsy is generally used to quantify heart allograft rejection and guide immunotherapy. Biopsy, however, is invasive, costly, and risky. Since rejection requires lymphocyte activation, the purpose of this study was to assess alternative methods to evaluate rejection dynamics by investigating serum level...

journal_title：Immunological investigations

authors： Chang DM,Ding YA,Kuo SY,Chang ML,Wei J

更新日期：1996-01-01 00:00:00