Downregulation of inflammatory mediators and pro-inflammatory cytokines by alkaloids of Jeevaneeya rasayana in adjuvant-induced arthritis.

abstract：:Electron microscopy (EM) is a valuable tool in diagnostic medicine, and in some cases, can be enhanced by immunological methods. A major medical application of EM, diagnostic virology, can frequently be augmented by employment of immunological reagents. Three immunoelectron microscopy (IEM) methods, aggregation, coati...

journal_title：Immunological investigations

authors： Miller SE,Howell DN

更新日期：1997-01-01 00:00:00

abstract：:The contribution of interleukin-2 (IL-2)-responsive bystander cells to the proliferative responses of human peripheral blood T lymphocytes to antigens used for sensitization such as Purified Protein Derivative (PPD), Tetanus toxoid (T T) and Influenza virus was investigated. Marked proliferation of the unfractionated ...

journal_title：Immunological investigations

authors： Sia DY,Chou JL

更新日期：1988-03-01 00:00:00

abstract：:This preliminary study examined the effects of immunization with Bacteroides macacae, the monkey equivalent of the human species of B. gingivalis on ligature-induced periodontitis. During a 12 week immunization period, 8 out of the 12 Macacae fasicularis monkeys were immunized weekly with B. macacae washed cells and 4...

journal_title：Immunological investigations

authors： Nisengard R,Blann D,Zelonis L,McHenry K,Reynolds H,Zambon J

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a chronic smoking-related lung disease associated with higher mortality and morbidity. Herein, we attempted to investigate the function of miR-558/TNF Receptor Superfamily Member 1A (TNFRSF1A) in the progression of COPD. METHODS:GEO database was applied to fil...

journal_title：Immunological investigations

authors： Jing X,Luan Z,Liu B

更新日期：2021-01-17 00:00:00

abstract：:VH4-34 gene encoded autoantibodies are elevated in systemic lupus erythematosus (SLE) and in other diseases associated with B-cell hyperproliferation/dysfunction. One of the autoantigens recognized by VH4-34-encoded antibodies are branched/linear poly N-acetyl lactosamine chains. Since the anti-carbohydrate response i...

journal_title：Immunological investigations

authors： Bhat NM,Kshirsagar MA,Bieber MM,Teng NN

更新日期：2015-01-01 00:00:00

abstract：:The aim of the study was to assess whether genotypes in the Toll-like receptor 4 gene and in the promoter of the interleukin-18 gene are associated with the susceptibility to chronic periodontitis. 108 chronic periodontitis patients and 76 controls were genotyped for c.896A>G/1196C>T (TLR4 gene) and for c.-368G>C/ c.-...

journal_title：Immunological investigations

authors： Noack B,Görgens H,Lorenz K,Schackert HK,Hoffmann T

更新日期：2009-01-01 00:00:00

abstract：:The objective of this study was to analyze how Staphylococcus epidermidis SCV and WT strains manipulate the PI3K/Akt/mTOR signaling pathway. Six S. epidermidis strains with normal phenotype (WT) and six S. epidermidis strains with SCV phenotype were isolated in parallel from six patients with the prosthetic hip joint ...

journal_title：Immunological investigations

authors： Magryś A,Bogut A,Kiełbus M,Olender A

更新日期：2018-04-01 00:00:00

abstract：:Functional defects of polymorphonuclear leukocytes can lead to clinical immunodeficiency. Understanding these conditions requires a knowledge of normal polymorph physiology and the means to analyse various aspects of polymorph function. Primary diseases of polymorph function are rare, whereas disorders secondary to ot...

journal_title：Immunological investigations

authors： Thompson RA

更新日期：1988-04-01 00:00:00

abstract：:Polycyclic aromatic hydrocarbons (PAHs) are widely distributed and relocated in the environment as a result of the incomplete combustion of organic matter. Many PAHs and their epoxides are highly toxic, mutagenic and/or carcinogenic to microorganisms as well as to higher systems including humans. BP is one of the most...

journal_title：Immunological investigations

authors： Ustinov VA,Studennikov AE,Vavilov VA,Tyumentseva MA,Morozova VV,Tikunova NV,Glushkov AN

更新日期：2015-01-01 00:00:00

abstract：:Rotaviruses were first recognized about 15 years ago in association with diarrhea in children and animals. Since then, rotaviruses have been determined to be the most important viral agent that causes clinically significant diarrhea in children and a need for an effective vaccination program has been recognized. This ...

journal_title：Immunological investigations

authors： Estes MK,Conner ME,Gilger MA,Graham DY

更新日期：1989-01-01 00:00:00

abstract：:DNA vaccines have been widely used to induce immune responses against molecular targets. In this study, we explored the possibility of using DNA vaccine combined with the immunosuppressant FK506 (tacrolimus) to antigen-specifically suppress unwanted immune responses and prevent autoimmune ovarian disease. To that end,...

journal_title：Immunological investigations

authors： Kang Y,Zheng G,Chen A,Wang J,Hu Y,Li J,Zhang J,Gao W,Fu H,Xia G,Wang B

更新日期：2012-01-01 00:00:00

abstract：:Major histocompatibility complex (MHC) restriction of antigen presentation of a single mucin1 (MUC1) variable number of tandem repeats peptide (VNTR1) was examined by generating cytotoxic T lymphocytes (CTL) derived from peripheral blood mononuclear cells (PBMC) stimulated with a single repeat MUC1 peptide presented b...

journal_title：Immunological investigations

authors： Orr MK,Burnside JS,Phillips CA,Philip R,Dombrowski KE,Wright SE

更新日期：2007-01-01 00:00:00

abstract：:In this study we examined a panel of CD4+ antigen specific/MHC restricted T cell clones for their ability to secrete IL-2, IL-4, and IFN-gamma upon stimulation with con A, three lymphokines which are diagnostic for the TH1 and TH2 subtypes of helper T cells. Eight of the twelve clones we analyzed did not fit the class...

journal_title：Immunological investigations

authors： Hatfield SM,Rodgers GH,Marder P,Roehm NW

更新日期：1991-02-01 00:00:00

abstract：:Immunological parameters previously shown to constitute an increased risk for progression towards AIDS have been observed in clinically asymptomatic individuals considered to be at risk for this syndrome. These parameters include severely decreased numbers of T helper cells (count below 400/mm3 blood for CD4+ cells we...

journal_title：Immunological investigations

authors： Mannhalter JW,Wolf HM,Pum M,Banekovich M,Hutterer J,Brandstätter R,Eibl MM

更新日期：1988-04-01 00:00:00

abstract：:Two monoclonal antibodies, D2A1 and D5G3 were elicited by immunization with a preparation of chicken egg riboflavin carrier protein which had been reduced and carboxymethylated. Epitopes recognised by the monoclonal antibodies were mapped using the Pepscan method. Epitopic determinants for D2A1 as well as D5G3 were id...

journal_title：Immunological investigations

authors： Lobo SC,Karande AA,Adiga PR

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Grass pollen is a major cause of allergy throughout the world. The only treatment targeting the causes and not only the symptoms of allergy is specific immunotherapy (IT). A number of controlled trials demonstrated the efficacy of IT in grass pollen allergic subjects, most using extracts of multiple grasses ...

journal_title：Immunological investigations

authors： Marcucci F,Sensi L,Di Cara G,Incorvaia C,Puccinelli P,Scurati S,Frati F

更新日期：2010-01-01 00:00:00

abstract：:Genome-wide association studies have led to the discovery of several susceptibility genes related to autoimmune thyroid diseases (AITDs). However, controversial results have been reported regarding the role of single-nucleotide polymorphism (SNP) of CD40 in the disease susceptibility. The objective of this study was t...

journal_title：Immunological investigations

authors： Wang D,Chen J,Zhang H,Zhang F,Yang L,Mou Y

更新日期：2017-08-01 00:00:00

abstract：:Objectives: Ataxia-telangiectasia (A-T) is an autosomal recessive neurodegenerative disorder with multisystem involvement caused by homozygous or compound heterozygous mutations in the ataxia telangiectasia mutated (ATM) gene which encodes a serine/threonine protein kinase. The aims of this study were to investigate c...

journal_title：Immunological investigations

authors： Amirifar P,Mozdarani H,Yazdani R,Kiaei F,Moeini Shad T,Shahkarami S,Abolhassani H,Delavari S,Sohani M,Rezaei A,Hassanpour G,Akrami SM,Aghamohammadi A

更新日期：2021-02-01 00:00:00

abstract：:Each functional gene illustrates the complexity of genetic predisposition to disease; however, it is difficult to bring out these traits with reference to autoimmune diseases like type 1 diabetes (T1D). To find out the genetic contribution of CTLA-4 + 49A/G, CTLA-4 -318C/T and CD28 + 17T/C polymorphisms toward T1D, th...

journal_title：Immunological investigations

authors： Gunavathy N,Asirvatham A,Chitra A,Jayalakshmi M

更新日期：2019-08-01 00:00:00

abstract：:Intravenous immunoglobulins (IVIg) have been used as an immunomodulatory therapy in a variety of diseases. Several mechanisms of action have been proposed, one of which is interference with the cytokine network. We have investigated the effect of IVIg on the cytotoxicity of human TNF alpha. IVIg was capable of protect...

journal_title：Immunological investigations

authors： Stangel M,Schumacher HC,Ruprecht K,Boegner F,Marx P

更新日期：1997-08-01 00:00:00

abstract：:IL-3-like activity (IL-3-LA) is a growth factor that stimulates stem cell maturation. We examined the production of IL-3-LA by peripheral blood mononuclear cells of 10 patients with relapsing-remitting multiple sclerosis (MS) following one year of treatment with intravenous immunoglobulins (IVIG). The results were com...

journal_title：Immunological investigations

authors： Djaldetti R,Achiron A,Ziv I,Djaldetti M,Melamed E,Fishman P

更新日期：1995-08-01 00:00:00

abstract：:As a result of strong experimental data supporting effectiveness and safety, herb-based immunomodulators are paving way as alternative sources of potent adjuvants for vaccines. In this study, the immunostimulatory and adjuvant properties of AcF1, a flavonoids-rich fraction of Alchornea cordifolia extract, was evaluate...

journal_title：Immunological investigations

authors： Nworu CS,Esimone CO,Tenbusch M,Nabi G,Proksch P,Uberla K,Temchura VV

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Diabetic peripheral neuropathy (DPN) is one of late complications of diabetes mellitus. The aim of this study was to evaluate the association between variable number tandem repeat (VNTR) polymorphism in intron 3 of interleukin-4 gene and risk of DPN. METHODS:We examined 926 T2DM patients and 420 healthy cont...

journal_title：Immunological investigations

authors： Buraczynska M,Buraczynska K,Zukowski P,Ksiazek A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate serum levels of immunosuppressive cytokines TGF beta 1 and VEGF and count of immune cells in peripheral blood in stage II and III colorectal cancer patients. METHODS:Blood samples were collected from 22 colorectal patients and 25 healthy controls before the sta...

journal_title：Immunological investigations

authors： Spacek J,Vocka M,Netikova I,Skalova H,Dundr P,Konopasek B,Zavadova E,Lubos P

更新日期：2018-10-01 00:00:00

abstract：:A disintegrin and metalloproteinases (ADAMs) are believed to be involved in the pathogenesis of many fibrosis-related diseases. However, little is known regarding the significance of ADAM17 as a biomarker for interstitial lung disease (ILD). In this study, by using the RT-PCR, western blotting and ELISA, we detected t...

journal_title：Immunological investigations

authors： Ge J,Tang L,Mu P,Zhu F,Xie L,Tang Y

更新日期：2020-02-01 00:00:00

abstract：:Lymphotoxin beta receptor (LTBR) is essential for development and organization of the secondary lymphoid tissues. To investigate whether LTBR polymorphisms are associated with IgA nephropathy (IgAN) in Korean children, One hundred ninety nine patients with IgAN and 289 controls were recruited. Two promoter single nucl...

journal_title：Immunological investigations

authors： Kim SK,Lee JY,Jeong Park H,Chung JH,Suh JS,Hahn WH,Cho BS,Kim MJ

更新日期：2012-01-01 00:00:00

abstract：:An enzyme-linked immunoassay (EIA) is described and evaluated which quantitates human antibodies to serotype specific S. pneumoniae polysaccharide (PnPs) in human sera. Based on the observations previously described by Koskela (1), native PnPs are used as coating antigens and sera are absorbed with a soluble pneumococ...

journal_title：Immunological investigations

authors： Quataert S,Martin D,Anderson P,Giebink GS,Henrichsen J,Leinonen M,Granoff DM,Russell H,Siber G,Faden H,Barnes D,Madore DV

更新日期：2001-08-01 00:00:00

abstract：:Th17 cells of the intestine and colon can produce several important cytokines during mucosal inflammation. However, few studies have focused on the role of IL-26 in intestinal inflammations. Colonic epithelial cells express receptors for IL-26, and this cytokine has been shown to induce the HT-29 colonic epithelial ce...

journal_title：Immunological investigations

authors： Weishaar IM,Young RS,Wiles BM,McGee DW

更新日期：2019-11-01 00:00:00

abstract：:In a previous study, we noticed that some ascitic cells isolated from melanoma patients survive, proliferate, and differentiate into giant phagocytes after the other cells died. Similar phenomena were observed in the primary cultures of mouse lung and liver cells. In the present study, the effects of dying cells on ab...

journal_title：Immunological investigations

authors： Yuan X,Li X,Zhang Q,Zhang C,Yang Z,Li D

更新日期：2013-01-01 00:00:00

abstract：:The lectin from Amaranthus leucocarpus (ALL) is specific for N-acetyl-D-galactosamine and inhibits phagocytosis of Leishmania mexicana promastigotes in Balb/c mice peritoneal macrophages by 38%. The lipophosphoglycan (LPG) purified from L. mexicana inhibits penetration of promastigotes into peritoneal macrophages by 3...

journal_title：Immunological investigations

authors： Gorocica P,Hernández P,Perez A,Chávez R,Baez R,Zenteno E,Lascurain R

更新日期：2000-11-01 00:00:00