Flow cytometric quantification of T cell proliferation and division kinetics in woodchuck model of hepatitis B.

abstract：:Endomyocardial biopsy is generally used to quantify heart allograft rejection and guide immunotherapy. Biopsy, however, is invasive, costly, and risky. Since rejection requires lymphocyte activation, the purpose of this study was to assess alternative methods to evaluate rejection dynamics by investigating serum level...

journal_title：Immunological investigations

authors： Chang DM,Ding YA,Kuo SY,Chang ML,Wei J

更新日期：1996-01-01 00:00:00

abstract：:In the last 15 years, it has become apparent that ovarian cancer is recognized by the immune system, taking into account that T cell infiltration can be associated with increased overall survival. Several studies indicate that a correct combination of cluster of differentiation 8 and cluster of differentiation 4 T cel...

journal_title：Immunological investigations

authors： Singh M,Loftus T,Webb E,Benencia F

更新日期：2016-11-01 00:00:00

abstract：:Although cancer immunotherapy, which is able to target specifically cancer cells without detrimental effects to normal cell functions, would serve as an ideal therapeutic modality, most of the randomized clinical trials of cancer immunotherapy have not demonstrated a meaningful survival benefit to cancer patients over...

journal_title：Immunological investigations

authors： Kim SJ,Ha GH,Kim SH,Kang CD

更新日期：2014-01-01 00:00:00

abstract：:Anti-galactocerebroside (GalC) antibodies have been reported to inhibit myelin formation, cause demyelination, and block HIV-I infection of neural cells. We examined the binding of 3 monoclonal and polyclonal anti-GalC antibodies to a panel of purified glycolipids by ELISA and by an immunospot assay on nitrocellulose ...

journal_title：Immunological investigations

authors： McAlarney T,Ogino M,Apostolski S,Latov N

更新日期：1995-05-01 00:00:00

abstract：:Experimental autoimmune uveoretinitis (EAU) was induced in rats by immunization with bovine interphotoreceptor retinoid-binding protein (IRBP) and studied by immunohistochemistry. In general, the IRBP induction of inflammatory cellular components and expression of immune-related antigens on various non-lymphoid cells ...

journal_title：Immunological investigations

authors： Chan CC,Nussenblatt RB,Wiggert B,Redmond TM,Fujikawa LS,Chader GJ,Gery I

更新日期：1987-03-01 00:00:00

abstract：:Adenoid hypertrophy is the most common cause of upper airway obstruction and sleep-disordered breathing in children, yet its pathogenesis remains unclear. The identification of the novel helper T cell subsets, Th17 cells and regulatory T cells (Tregs) could provide new insight into our understanding of the mechanisms ...

journal_title：Immunological investigations

authors： Sade K,Fishman G,Kivity S,DeRowe A,Langier S

更新日期：2011-01-01 00:00:00

abstract：:Drug abuse has become a global health concern. Understanding how drug abuse modulates the immune system and how the immune system responds to pathogens associated with drug abuse, such hepatitis C virus (HCV) and human immunodeficiency virus (HIV-1), can be assessed by an integrated approach comparing proteomic analys...

journal_title：Immunological investigations

authors： Reynolds JL,Mahajan SD,Aalinkeel R,Nair B,Sykes DE,Schwartz SA

更新日期：2009-01-01 00:00:00

abstract：:Objectives: Ataxia-telangiectasia (A-T) is an autosomal recessive neurodegenerative disorder with multisystem involvement caused by homozygous or compound heterozygous mutations in the ataxia telangiectasia mutated (ATM) gene which encodes a serine/threonine protein kinase. The aims of this study were to investigate c...

journal_title：Immunological investigations

authors： Amirifar P,Mozdarani H,Yazdani R,Kiaei F,Moeini Shad T,Shahkarami S,Abolhassani H,Delavari S,Sohani M,Rezaei A,Hassanpour G,Akrami SM,Aghamohammadi A

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:This study aimed to examine the association of three functional IRF5 rs10954213, rs3757385, and rs41298401 polymorphisms with susceptibility to unexplained recurrent pregnancy loss (RPL) among Iranian women from south of Iran. METHODS:176 women with unexplained RPL and 173 healthy postmenopausal controls wer...

journal_title：Immunological investigations

authors： Amiri Jahromi R,Nasiri M,Jahromi AR

更新日期：2017-01-01 00:00:00

abstract：:Corneal transplant is the most common solid tissue transplant in humans. Advances in microsurgical techniques, eye banking and the use of corticosteroids have improved the success of corneal transplants. Over 65,000 corneal transplants are being performed worldwide annually. Most of these transplants are performed in ...

journal_title：Immunological investigations

authors： Kumar V,Kumar A

更新日期：2014-01-01 00:00:00

abstract：:VH4-34 gene encoded autoantibodies are elevated in systemic lupus erythematosus (SLE) and in other diseases associated with B-cell hyperproliferation/dysfunction. One of the autoantigens recognized by VH4-34-encoded antibodies are branched/linear poly N-acetyl lactosamine chains. Since the anti-carbohydrate response i...

journal_title：Immunological investigations

authors： Bhat NM,Kshirsagar MA,Bieber MM,Teng NN

更新日期：2015-01-01 00:00:00

abstract：:A rapid, quantitative enzyme-linked immunosorbent assay (ELISA) for the immunodiagnosis of Chagas' disease is described. The ELISA was standardized with the Falcon assay screening test (F.A.S.T.) system using a purified Trypanosoma cruzi epimastigote fraction (PEF) obtained by ion exchange chromatography. The ELISA te...

journal_title：Immunological investigations

authors： Partel CD,Rossi CL

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Association studies of genes encoding cytokines that play an important role in inflammatory response represent one approach to finding type 1 diabetes (T1D) disease genes. The aim of this study was to investigate the association of single nucleotide polymorphisms (SNPs) within cytokine genes with T1D in a co...

journal_title：Immunological investigations

authors： Allam G,Nasr A,Talaat IM,Abuelsaad ASA,Bakheit AM,Nemenqani D,Alsulaimani AA

更新日期：2018-04-01 00:00:00

abstract：:In the last 10 years many of the superantigens of the microbial world have been defined and the mechanisms of cellular interaction between lymphocytes and antigen presenting cells has been elucidated in great detail. The consequences of superantigen stimulation of the immune system, though less well defined, can be co...

journal_title：Immunological investigations

authors： Stevens DL

更新日期：1997-01-01 00:00:00

abstract：:Plasmodium falciparum CTL epitope minigenes containing HLA-A2 and HLA-B7 subtype supermotifs were cloned into a plasmid expression vector; this expression was measured in eight human HLA class I molecule specific cell lines. Three assays for in vitro antigen presentation analysis were developed to examine the cross-bi...

journal_title：Immunological investigations

authors： Tang Y,Lin Y,Mao Y,Dong M,Wang H

更新日期：2003-02-01 00:00:00

abstract：:Intravenous immunoglobulins (IVIg) have been used as an immunomodulatory therapy in a variety of diseases. Several mechanisms of action have been proposed, one of which is interference with the cytokine network. We have investigated the effect of IVIg on the cytotoxicity of human TNF alpha. IVIg was capable of protect...

journal_title：Immunological investigations

authors： Stangel M,Schumacher HC,Ruprecht K,Boegner F,Marx P

更新日期：1997-08-01 00:00:00

abstract：:This preliminary study examined the effects of immunization with Bacteroides macacae, the monkey equivalent of the human species of B. gingivalis on ligature-induced periodontitis. During a 12 week immunization period, 8 out of the 12 Macacae fasicularis monkeys were immunized weekly with B. macacae washed cells and 4...

journal_title：Immunological investigations

authors： Nisengard R,Blann D,Zelonis L,McHenry K,Reynolds H,Zambon J

更新日期：1989-01-01 00:00:00

abstract：:Different studies described the antibacterial properties of Lavandula angustifolia (Mill.) essential oil and its anti-inflammatory effects. Besides, no data exist on its ability to activate human macrophages during the innate response against Staphylococcus aureus. The discovery of promising regulators of macrophage-m...

journal_title：Immunological investigations

authors： Giovannini D,Gismondi A,Basso A,Canuti L,Braglia R,Canini A,Mariani F,Cappelli G

更新日期：2016-01-01 00:00:00

abstract：:In a previous study, we noticed that some ascitic cells isolated from melanoma patients survive, proliferate, and differentiate into giant phagocytes after the other cells died. Similar phenomena were observed in the primary cultures of mouse lung and liver cells. In the present study, the effects of dying cells on ab...

journal_title：Immunological investigations

authors： Yuan X,Li X,Zhang Q,Zhang C,Yang Z,Li D

更新日期：2013-01-01 00:00:00

abstract：:Very little is known about the effects of acute psychological stress on the production of reactive oxygen species (ROS) by human phagocytic cells and the interplay between subjectively perceived stress, mediating hormones, variations in the number of peripheral leukocytes and ROS production. We measured psychological ...

journal_title：Immunological investigations

authors： Atanackovic D,Brunner-Weinzierl MC,Kröger H,Serke S,Deter HC

更新日期：2002-05-01 00:00:00

abstract：:Food allergy is an important and common health issue, and there is a need to identify and characterize the sensitizing mechanisms. One of the common causes of food allergy is ovalbumin (OVA), a dietary antigen from eggs. We hypothesized that OVA-induced food allergy in the gut involves the activation of the chemokine ...

journal_title：Immunological investigations

authors： Lee JB,Matsumoto T,Shin YO,Yang HM,Min YK,Timothy O,Bae SJ,Quan FS

更新日期：2004-02-01 00:00:00

abstract：:Recently, we reported the preparation and antigen-presenting properties of hybridoma B-cell clones obtained after fusing non-secreting, non-antigen presenting Balb/c 653-myeloma cells with non-immune SJL spleen cells. It was found that antigen presentation at the clonal level can be specific or non-specific, depending...

journal_title：Immunological investigations

authors： Cohly HH,Morrison DR,Atassi MZ

更新日期：1989-10-01 00:00:00

abstract：:IL-2 production by the phytohemaglutinin (PHA)-stimulated mononuclear cells (MNC) of peripheral blood (PB) and synovial fluid (SF) from patients with rheumatoid arthritis (RA), other arthritic diseases (OAD) and age-matched normal controls were studied, and the activity of IL-2 inhibitor in sera of studied subject was...

journal_title：Immunological investigations

authors： Wu CH,Jeng KC,Lan JL

更新日期：1995-11-01 00:00:00

abstract：:Hematological disorders like Aplastic anemia are quite frequent in Pakistan. Human leukocyte antigen (HLA) system, have been implicated in the development of Aplastic anemia in various population-based studies, The aim of this study was to determine the role of the HLA Class I and Class II alleles in genetic susceptib...

journal_title：Immunological investigations

authors： Rehman S,Saba N,Khalilullah,Munir S,Ahmed P,Mehmood T

更新日期：2009-01-01 00:00:00

abstract：:Interleukin (IL)-10 response is associated with mortality in patients with sepsis. IL-10 is primarily produced by monocytes and type 2 T helper (Th2) cells. The aim of this study was to investigate differences in IL-10 production between monocytes and Th2 cells in patients with sepsis. Forty patients with sepsis and 3...

journal_title：Immunological investigations

authors： Wu HP,Chu CM,Kao KC,Huang SH,Chuang DY

更新日期：2017-05-01 00:00:00

abstract：:DNA vaccines have been widely used to induce immune responses against molecular targets. In this study, we explored the possibility of using DNA vaccine combined with the immunosuppressant FK506 (tacrolimus) to antigen-specifically suppress unwanted immune responses and prevent autoimmune ovarian disease. To that end,...

journal_title：Immunological investigations

authors： Kang Y,Zheng G,Chen A,Wang J,Hu Y,Li J,Zhang J,Gao W,Fu H,Xia G,Wang B

更新日期：2012-01-01 00:00:00

abstract：:A previous study has demonstrated that both interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS) were needed to induce the production of nitric oxide (NO) in BNL CL.2 cells, murine embryonic liver cells. We here demonstrate that when BNL CL.2 cells were cultured with serum-free medium, they were induced to produc...

journal_title：Immunological investigations

authors： Pae HO,Yoo JC,Choi BM,Paik SG,Kim YH,Jin HS,Chung HT

更新日期：1999-03-01 00:00:00

abstract：:Although the T cell costimulatory molecules CD2 and CD28 are enriched within the immunological synapse (IS), it has been suggested that costimulatory molecules need not be localized to the contact site between a T cell and an antigen-presenting cell (APC) in order to costimulate T cell activation. To determine whether...

journal_title：Immunological investigations

authors： Watson CL,Furlong SJ,Hoskin DW

更新日期：2008-01-01 00:00:00

abstract：:Dendritic cells (DCs) are potent antigen-presenting cells that can be matured in vitro from immature dendritic cells (iDCs) in the presence of several biological agents such as cytokine cocktail, CD40L, TNF-a and antigen loading, which are necessary and achieved using various protocols, such as lipofection, passive pu...

journal_title：Immunological investigations

authors： Son CH,Bae JH,Shin DY,Lee HR,Choi YH,Yang K,Park YS

更新日期：2013-01-01 00:00:00

abstract：:Bromelain has been reported to have anti-inflammatory and immunomodulatory effects. However, the anti-inflammatory mechanism of bromelain is unclear. Therefore, we investigated the effect of bromelain on cytokine production from lipopolysaccharide (LPS)-stimulated human peripheral blood mononuclear cells (PBMC) and mo...

journal_title：Immunological investigations

authors： Huang JR,Wu CC,Hou RC,Jeng KC

更新日期：2008-01-01 00:00:00