A rapid, quantitative enzyme-linked immunosorbent assay (ELISA) for the immunodiagnosis of Chagas' disease.

abstract：OBJECTIVE:This study determined whether tumor necrosis factor alpha (TNF-α) and Interleukin-10 (IL-10) polymorphisms are associated with susceptibility to dengue. METHODS:a systematic review with meta-analysis was conducted of the associations between the TNF-α (-308G/A) and IL-10 (-819C/T) polymorphisms and dengue. ...

journal_title：Immunological investigations

authors： Santos AC,de Moura EL,Ferreira JM,Santos BR,Alves VM,de Farias KF,de Souza Figueiredo EV

更新日期：2017-02-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) is a dietary fatty acid which causes extensive remodeling and mast cell recruitment in the mouse mammary gland. Two CLA isomers, 9,11- and 10,12-CLA, have differing effects in vivo, with only 10,12-CLA increasing mast cell number. The purpose of this project is to test the hypothesis tha...

journal_title：Immunological investigations

authors： Krishnan S,Russell J,Bodziak M,Koury S,Masso-Welch P

更新日期：2012-01-01 00:00:00

abstract：:Polycyclic aromatic hydrocarbons (PAHs) are widely distributed and relocated in the environment as a result of the incomplete combustion of organic matter. Many PAHs and their epoxides are highly toxic, mutagenic and/or carcinogenic to microorganisms as well as to higher systems including humans. BP is one of the most...

journal_title：Immunological investigations

authors： Ustinov VA,Studennikov AE,Vavilov VA,Tyumentseva MA,Morozova VV,Tikunova NV,Glushkov AN

更新日期：2015-01-01 00:00:00

abstract：:The effect of two Chinese traditional drugs, Dang Gui injection prepared from Angelica sinensis and C 21 Ester glucoside (GB) extracted from Cynanchus auriculatus on in vitro production of IL-2 has been studied. The IL-2 was produced by Con A stimulation of mouse spleen mononuclear cells. The IL-2 activity was assayed...

journal_title：Immunological investigations

authors： Weng XC,Zhang P,Gong SS,Xiai SW

更新日期：1987-04-01 00:00:00

abstract：:Mice were immunized with 14 free (i.e. not conjugated to any carrier) synthetic peptides representing the entire human hemoglobin alpha-chain. Antibodies against each peptide were determined using solid phase radioimmunoassay, both with free peptides and peptides coupled to a protein carrier as the coating antigen. It...

journal_title：Immunological investigations

authors： Oshima M,Atassi MZ

更新日期：1989-08-01 00:00:00

abstract：:Each functional gene illustrates the complexity of genetic predisposition to disease; however, it is difficult to bring out these traits with reference to autoimmune diseases like type 1 diabetes (T1D). To find out the genetic contribution of CTLA-4 + 49A/G, CTLA-4 -318C/T and CD28 + 17T/C polymorphisms toward T1D, th...

journal_title：Immunological investigations

authors： Gunavathy N,Asirvatham A,Chitra A,Jayalakshmi M

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To assess cellular composition and local cytokine response in vitreous humor of tubercular uveitis. METHODS:Cells were collected from vitreous cassettes and peripheral blood of 8 tubercular uveitis and 5 control subjects, undergoing vitrectomy and analyzed by flow cytometry for cellular composition, activation...

journal_title：Immunological investigations

authors： Sharma RK M.Sc,Gupta V M.S,Bansal R M.S,Sharma K M.D,Gupta A M.S,Sachdeva N Ph.D

更新日期：2018-08-01 00:00:00

abstract：:Vitamin D deficiency and vitamin D receptor (VDR) gene polymorphisms have been reported in autoimmune diseases. However, their role in Behçet's disease (BD) and scleroderma remains inconclusive. Our aim was to evaluate vitamin D receptor (ApaI, TaqI) gene polymorphisms in relation to Behçet's disease and scleroderma i...

journal_title：Immunological investigations

authors： Kamal A,Gamal SM,Elgengehy FT,Alkemary AK,Siam I

更新日期：2016-08-01 00:00:00

abstract：:Monocyte chemoattractant protein 1 (MCP-1) plays an important role in the development of periodontitis. The purpose of this investigation was to evaluate association of the  MCP-1 gene polymorphism with chronic periodontitis in patients with end-stage renal disease (ESRD). One hundred fifty ESRD patients with chronic ...

journal_title：Immunological investigations

authors： Ksiazek K,Buraczynska M

更新日期：2020-11-01 00:00:00

abstract：:We investigated the functional and subset surface marker characteristics of supramammary lymph node T cell populations at sites proximal and distal to the mammary region of goats repeatedly injected with heat-treated Staphylococcus aureus antigen (HK-SAC). Flow cytometric studies showed quantitative differences in CD4...

journal_title：Immunological investigations

authors： Dobrzanski MJ,Yang TJ

更新日期：1992-04-01 00:00:00

abstract：:Electroeluted outer membrane proteins [(EOmp), (35-37 KDa, porins)] were highly immunogenic in New Zealand White rabbits. An ELISA peak titer of 51,200 to EOmp as compared to 6,400 for non-eluted outer membrane protein (Omp) was demonstrated. EOmp enhanced the antigenicity of Omp possibly due to epitopes which were ma...

journal_title：Immunological investigations

authors： Kawahara M,Human LG,Kawahara K,Domingue GJ

更新日期：1994-04-01 00:00:00

abstract：:The occurrence of apoptosis in cultured blood cells from HIV+ patients is well-documented. However, the relationship of this process to cytokine production is still undefined. We measured the production of TNF-beta by mitogen-stimulated PBLs from 33 HIV+ patients, while simultaneously assessing their development of ap...

journal_title：Immunological investigations

authors： Lavergne JA,Zorrilla C,del Llano AM

更新日期：1996-07-01 00:00:00

abstract：:The critical contribution of CD4+CD25+Foxp3+ T-regulatory cells (Treg) to immune suppression in the tumor microenvironment is well-established. Whereas the mechanisms that drive the generation and accumulation of Treg in tumors have been an active area of study, the information on their origin and population dynamics ...

journal_title：Immunological investigations

authors： Li Q,Egilmez NK

更新日期：2016-11-01 00:00:00

abstract：:Neutrophil chemotactic defects have been reported previously in patients with hyper-IgE syndrome. Bi-allelic mutations in dedicator of cytokinesis 8 (DOCK8) gene usually cause an autosomal recessive hyper-IgE syndrome phenotype. Data are lacking about expression of DOCK8 protein in neutrophils or the possible role of ...

journal_title：Immunological investigations

authors： Mandola AB,Levy J,Nahum A,Hadad N,Levy R,Rylova A,Simon AJ,Lev A,Somech R,Broides A

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The objective of this study was to investigate serum levels of immunosuppressive cytokines TGF beta 1 and VEGF and count of immune cells in peripheral blood in stage II and III colorectal cancer patients. METHODS:Blood samples were collected from 22 colorectal patients and 25 healthy controls before the sta...

journal_title：Immunological investigations

authors： Spacek J,Vocka M,Netikova I,Skalova H,Dundr P,Konopasek B,Zavadova E,Lubos P

更新日期：2018-10-01 00:00:00

abstract：:Anti-α-galactoside antibody (anti-Gal) from human plasma that bound to α-galactoside-bearing guar galactomannan gel and was eluted with specific sugar (affinity-purified anti-Gal ; APAG) invariably contained apo(a) and apo B subunits in a proportion close to that in plasma lipoprotein(a) [Lp(a)]. Since LDL does not co...

journal_title：Immunological investigations

authors： Mandagini G,Subramanian SP,Vasantha K,Appukuttan PS

更新日期：2013-01-01 00:00:00

abstract：:The contribution of interleukin-2 (IL-2)-responsive bystander cells to the proliferative responses of human peripheral blood T lymphocytes to antigens used for sensitization such as Purified Protein Derivative (PPD), Tetanus toxoid (T T) and Influenza virus was investigated. Marked proliferation of the unfractionated ...

journal_title：Immunological investigations

authors： Sia DY,Chou JL

更新日期：1988-03-01 00:00:00

abstract：:Plasmodium falciparum CTL epitope minigenes containing HLA-A2 and HLA-B7 subtype supermotifs were cloned into a plasmid expression vector; this expression was measured in eight human HLA class I molecule specific cell lines. Three assays for in vitro antigen presentation analysis were developed to examine the cross-bi...

journal_title：Immunological investigations

authors： Tang Y,Lin Y,Mao Y,Dong M,Wang H

更新日期：2003-02-01 00:00:00

abstract：:Recently, we reported the preparation and antigen-presenting properties of hybridoma B-cell clones obtained after fusing non-secreting, non-antigen presenting Balb/c 653-myeloma cells with non-immune SJL spleen cells. It was found that antigen presentation at the clonal level can be specific or non-specific, depending...

journal_title：Immunological investigations

authors： Cohly HH,Morrison DR,Atassi MZ

更新日期：1989-10-01 00:00:00

abstract：:DNA vaccines have been widely used to induce immune responses against molecular targets. In this study, we explored the possibility of using DNA vaccine combined with the immunosuppressant FK506 (tacrolimus) to antigen-specifically suppress unwanted immune responses and prevent autoimmune ovarian disease. To that end,...

journal_title：Immunological investigations

authors： Kang Y,Zheng G,Chen A,Wang J,Hu Y,Li J,Zhang J,Gao W,Fu H,Xia G,Wang B

更新日期：2012-01-01 00:00:00

abstract：:Although cancer immunotherapy, which is able to target specifically cancer cells without detrimental effects to normal cell functions, would serve as an ideal therapeutic modality, most of the randomized clinical trials of cancer immunotherapy have not demonstrated a meaningful survival benefit to cancer patients over...

journal_title：Immunological investigations

authors： Kim SJ,Ha GH,Kim SH,Kang CD

更新日期：2014-01-01 00:00:00

abstract：:Objectives: Type 1 diabetes mellitus (T1D) has been disclosed to be associated with an elevated risk of cardiovascular disease (CVD), as well as increased risks of losing bone mass and progression of osteoporosis (OP). Osteoprotegerin (OPG), as a decoy receptor, has been demonstrated to play a critical role in bone me...

journal_title：Immunological investigations

authors： Duan CC,Ma C,Tang HQ

更新日期：2021-02-01 00:00:00

abstract：:In recent studies, using a swine model of single lung transplantation, we demonstrated that IRI alone increased MHC II expression in the host's peripheral T lymphocytes. The inhibition of increased MHC II expression with TCV-309, a specific platelet-activating factor (PAF) antagonist suggested that PAF might play a ro...

journal_title：Immunological investigations

authors： Nikbakht-Sangari M,Qayumi AK,Keown P,Duronio V,Horley K

更新日期：1999-07-01 00:00:00

abstract：:Prolonged survival of C57BL/6 (B6) mice bearing syngenic EL-4 leukemia cells resulted from immunization with irradiated EL-4 cells on the day of inoculation of live leukemia cells. No prolongation of survival was observed if the irradiated cells were injected 6 or 13 days after live cell inoculation. Protection also w...

journal_title：Immunological investigations

authors： Abeyounis CJ,Bekierkunst A,Milgrom F

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Cancer immunotherapies have achieved much success and have become the forefront treatment of cancers previously associated with poor prognosis. However, a major challenge in cancer immunotherapies remains the heterogeneity of the immunoregulatory capacities of cancers, and not all patients of a given cancer ...

journal_title：Immunological investigations

authors： Andersen MM,Larsen J,Hansen M,Pedersen AE,Gad M

更新日期：2020-06-23 00:00:00

abstract：:It has become apparent that extreme environmental conditions of Antarctic continent alters many immune responses. The present study was conducted on 28th Indian Antarctic expeditioners. The investigations were carried out to explore the effect of multiple stresses like isolation, cold and UV exposure on human immunity...

journal_title：Immunological investigations

authors： Mishra KP,Yadav AP,Shweta,Chanda S,Ganju L,Majumdar D,Ilavazhagan G

更新日期：2010-01-01 00:00:00

abstract：:The bacterial superantigen Staphylococcal enterotoxin-A (SEA), produced by some strains of Staphylococcus aureus, causes proliferation of cytotoxic T-lymphocytes and cytokine production in vivo. SEA has been shown to be highly efficient for antibody-targeted superantegen immunotherapy for different tumor models. A can...

journal_title：Immunological investigations

authors： Mondal TK,Bhatta D,Biswas S,Pal P

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Infections are usually involved in the pathogenesis of spondyloarthritis (SpA). Mannose-binding lectin (MBL) is a component of the innate immune system with an important role in microbial defense. OBJECTIVE:To study the prevalence of MBL deficiency in SpA patients as well as its influence in the clinical pr...

journal_title：Immunological investigations

authors： Skare TL,Nisihara R,Cieslinski JZ,Zeni JO,Rasera HN,Messias-Reason I,Utiyama SR

更新日期：2017-02-01 00:00:00

abstract：:We tested by Western blot several thousand antibody-secreting human cell lines immortalized by hybridoma fusion or Epstein-Barr virus transformation of peripheral blood lymphocytes from patients with systemic lupus erythematosus or mixed connective tissue disease. The blots utilized total human Jurkat cell extract as ...

journal_title：Immunological investigations

authors： Vanderslice WE,Takeda Y,Chen J,Sharp GC,Pettersson I,Rosen A,Wigzell H,Wang RJ

更新日期：1988-06-01 00:00:00

abstract：:Many proteins of various origins are able to form complexes with Immunoglobulin G using reaction sites formed by residues of constant domains. Studies of IgG complexes of non-immune nature are important as biologically active proteins could escape from the circulation forming complexes with IgG as well as with other s...

journal_title：Immunological investigations

authors： Nezlin R,Bengtsson AA

更新日期：2008-01-01 00:00:00