Association of VDR ApaI and TaqI Gene Polymorphisms with the Risk of Scleroderma and Behçet's Disease.

abstract：:A previous study has demonstrated that both interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS) were needed to induce the production of nitric oxide (NO) in BNL CL.2 cells, murine embryonic liver cells. We here demonstrate that when BNL CL.2 cells were cultured with serum-free medium, they were induced to produc...

journal_title：Immunological investigations

authors： Pae HO,Yoo JC,Choi BM,Paik SG,Kim YH,Jin HS,Chung HT

更新日期：1999-03-01 00:00:00

abstract：:Flow cytometric analyses of immune cell proliferation, differentiation, and function are limited by the number of different fluorochromes that can be resolved simultaneously. Additional colors to expand functional analytic capability will facilitate higher dimensional analyses of heterogeneous cell populations by basi...

journal_title：Immunological investigations

authors： Bantly AD,Gray BD,Breslin E,Weinstein EG,Muirhead KA,Ohlsson-Wilhelm BM,Moore JS

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Changes in cytokine expression have been frequently found in patients with inflammatory bowel disease (IBD). Cytokine values outside the normal range may be somewhat related to common polymorphisms within cytokine genes. OBJECTIVE:The present study was designed to investigate the possible association betwee...

journal_title：Immunological investigations

authors： Ebrahimi Daryani N,Saghazadeh A,Moossavi S,Sadr M,Shahkarami S,Soltani S,Farhadi E,Rezaei N

更新日期：2017-10-01 00:00:00

abstract：:A colorimetric microadhesion assay that allows the quantitative determination of carcinoembryonic antigen (CEA)-mediated homophilic cell adhesion to CEA immobilized on 96-well polyvinyl chloride plates is described. Chinese hamster ovary (CHO) cells transfected with a full-length CEA cDNA were used as indicator cells....

journal_title：Immunological investigations

authors： Kuwahara M,Kuroki M,Haruno M,Murakami M,Arakawa F,Oikawa S,Nakazato H,Matsuoka Y

更新日期：1994-11-01 00:00:00

abstract：:Seven commercially available intravenous immunoglobulins (IVIG) preparations, a gamma globulin prepared by ethanol fractionation, and an experimental IgG isolated by a chromatographic procedure were compared in several tests. Split products were present in preparations manufactured by procedures involving protease tre...

journal_title：Immunological investigations

authors： Medgyesi GA,Kovács J,Füst G,Merétey K

更新日期：1988-04-01 00:00:00

abstract：:IL-2 production by the phytohemaglutinin (PHA)-stimulated mononuclear cells (MNC) of peripheral blood (PB) and synovial fluid (SF) from patients with rheumatoid arthritis (RA), other arthritic diseases (OAD) and age-matched normal controls were studied, and the activity of IL-2 inhibitor in sera of studied subject was...

journal_title：Immunological investigations

authors： Wu CH,Jeng KC,Lan JL

更新日期：1995-11-01 00:00:00

abstract：:Inoculation of metallic tin powder into Lewis rats resulted in marked enlargement of the draining lymph nodes. Plasma cells were the major contributors to the increase in cell mass. Certain immunologic aspects of this plasma cell lymphadenopathy were investigated. Immunoglobulin isotypes were distinguished and quantit...

journal_title：Immunological investigations

authors： Levine S,Saad A,Rappaport I

更新日期：1987-05-01 00:00:00

abstract：:We tested by Western blot several thousand antibody-secreting human cell lines immortalized by hybridoma fusion or Epstein-Barr virus transformation of peripheral blood lymphocytes from patients with systemic lupus erythematosus or mixed connective tissue disease. The blots utilized total human Jurkat cell extract as ...

journal_title：Immunological investigations

authors： Vanderslice WE,Takeda Y,Chen J,Sharp GC,Pettersson I,Rosen A,Wigzell H,Wang RJ

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Grass pollen is a major cause of allergy throughout the world. The only treatment targeting the causes and not only the symptoms of allergy is specific immunotherapy (IT). A number of controlled trials demonstrated the efficacy of IT in grass pollen allergic subjects, most using extracts of multiple grasses ...

journal_title：Immunological investigations

authors： Marcucci F,Sensi L,Di Cara G,Incorvaia C,Puccinelli P,Scurati S,Frati F

更新日期：2010-01-01 00:00:00

abstract：:Recently, we reported the preparation and antigen-presenting properties of hybridoma B-cell clones obtained after fusing non-secreting, non-antigen presenting Balb/c 653-myeloma cells with non-immune SJL spleen cells. It was found that antigen presentation at the clonal level can be specific or non-specific, depending...

journal_title：Immunological investigations

authors： Cohly HH,Morrison DR,Atassi MZ

更新日期：1989-10-01 00:00:00

abstract：:In this study, we aimed to explore the association among gene variants of five cytokines, tumor necrosis factor alpha (TNF-α), transforming growth factor beta-1 (TGF-β1), interferon gamma (IFN-γ), interleukin-6 (IL-6), and interleukin-10 (IL-10), and clinical parameters and prognosis in patients with multiple myeloma ...

journal_title：Immunological investigations

authors： Haydaroglu H,Oguzkan Balcı S,Pehlıvan S,Ozdıllı K,Gundogan E,Okan V,Nursal AF,Pehlıvan M

更新日期：2017-01-01 00:00:00

abstract：:The aim of the study was to assess whether genotypes in the Toll-like receptor 4 gene and in the promoter of the interleukin-18 gene are associated with the susceptibility to chronic periodontitis. 108 chronic periodontitis patients and 76 controls were genotyped for c.896A>G/1196C>T (TLR4 gene) and for c.-368G>C/ c.-...

journal_title：Immunological investigations

authors： Noack B,Görgens H,Lorenz K,Schackert HK,Hoffmann T

更新日期：2009-01-01 00:00:00

abstract：:Factors that suppress natural killer (NK) cell activity were examined in a random sample of 73 schizophrenic patients. NK activity in these patients were compared with 25 healthy age, sex and race matched controls. The mean percent of NK activity was 21% in the schizophrenic group compared with 30% percent in the cont...

journal_title：Immunological investigations

authors： Abdeljaber MH,Nair MP,Schork MA,Schwartz SA

更新日期：1994-08-01 00:00:00

abstract：:Alveolar macrophages (AM) freshly obtained by bronchoalveolar lavage suppressed significantly, in a dose-dependent fashion, lung interstitial lymphocytes cytotoxicity against the NK-sensitive target cells, YAC-1. Kinetic experiments revealed that AM-mediated suppression of NK activity was seen following short-term inc...

journal_title：Immunological investigations

authors： Lemaire I,St-Jean M

更新日期：1990-02-01 00:00:00

abstract：:Previous work had implicated T cells within the stimulating population as having a significant role in the MLR. We now report that depletion of T cells from the stimulators caused a reduction in proliferative response in mixed leukocyte reaction (MLR) by 50% or more. This response could be restored by adding T-enriche...

journal_title：Immunological investigations

authors： Roy C,Brown DL,Kaplan JG

更新日期：1986-03-01 00:00:00

abstract：:Anti-α-galactoside antibody (anti-Gal) from human plasma that bound to α-galactoside-bearing guar galactomannan gel and was eluted with specific sugar (affinity-purified anti-Gal ; APAG) invariably contained apo(a) and apo B subunits in a proportion close to that in plasma lipoprotein(a) [Lp(a)]. Since LDL does not co...

journal_title：Immunological investigations

authors： Mandagini G,Subramanian SP,Vasantha K,Appukuttan PS

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To study the relation between CD226 rs763361 gene polymorphism and CD226 serum level and to evaluate their role in susceptibility and disease activity of RA in a cohort of Egyptian individuals. METHODS:The serum level of CD226 was measured using a suitable ELISA kit and the CD226 rs763361 gene polymorphism w...

journal_title：Immunological investigations

authors： Mosaad YM,El-Toraby EE,Tawhid ZM,Abdelsalam AI,Enin AF,Hasson AM,Shafeek GM

更新日期：2018-04-01 00:00:00

abstract：:Woodchucks infected with woodchuck hepatitis virus (WHV) represent the closest natural animal model to study the immunopathogenesis of liver injury caused by essentially noncytopathic, highly human specific hepatitis B virus (HBV). The importance of antiviral T cell response in induction of hepatitis and in control of...

journal_title：Immunological investigations

authors： Gujar SA,Michalak TI

更新日期：2005-01-01 00:00:00

abstract：:Conventional plate ML-ELISA technique for diagnosis of recent cases of amoebiasis was converted into a simple polyvinyl chloride strip multilayer-enzyme linked immunosorbent assay (PVC strip ML-ELISA). This report details the development and preliminary characterization of the PVC strip ML-ELISA method for Entamoeba h...

journal_title：Immunological investigations

authors： Agarwal RK,Rawat R,Malaviya B,Das SR

更新日期：1991-12-01 00:00:00

abstract：:Thrombocytopenia as a complicating event in human immunodeficiency infection is a rather common hematological disorder and in many aspects resembles idiopathic(immune) thrombocytopenic purpura (ITP). Consequently, treatment of severe cases is similar to treating ITP, but steroids should be administered with particular...

journal_title：Immunological investigations

authors： Nydegger UE,Castelli D

更新日期：1991-04-01 00:00:00

abstract：:Whole-body hyperthermia (WBH) has been used as an adjunct approach to radio-/ chemotherapy for tumor therapy for many years. However, the molecular mechanism underlying the enhancement of tumor control is not clearly understood. It has been hypothesized that WBH might activate immune system by inducing the expression ...

journal_title：Immunological investigations

authors： Zhang H,Wang W,Zhang S,Huang W

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Adult chronic immune thrombocytopenic purpura (chronic ITP) is an autoimmune multifactorial bleeding disorder that occurs because of enhanced peripheral platelet destruction. Treatment decisions can be challenging because the goal of treatment is to prevent severe bleeding, but the risk of bleeding can be di...

journal_title：Immunological investigations

authors： El Ghannam D,Fawzy IM,Azmy E,Hakim H,Eid I

更新日期：2015-01-01 00:00:00

abstract：:We examined the blocking ability of poly(vinyl alcohol) (PVA) in enzyme immunoassays by coating polystyrene microtiter wells with PVA of different molecular weights (MW) and percent hydrolysis (%Hyd). Blocking ability was measured by the differences in non-specific binding of an anti-rabbit IgG-horseradish peroxidase ...

journal_title：Immunological investigations

authors： Rodda DJ,Yamazaki H

更新日期：1994-11-01 00:00:00

abstract：:To investigate whether phospholipase D1 (PLD1) is involved in autoimmune damage to the eyes, we used Western blotting and immunohistochemistry to examine the expression and distribution of PLD1 in the retinas of Lewis rats with experimental autoimmune uveoretinitis (EAU). Western blot analysis showed that the level of...

journal_title：Immunological investigations

authors： Kang J,Ahn M,Moon C,Min DS,Matsumoto Y,Shin T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Loquat leaf is an herb that is commonly used in traditional Chinese medicine (TCM) for its anti-inflammatory properties. Numerous studies have demonstrated that Th17 cells play a fundamental role in mediating SLE pathological deterioration. In our study, we investigated the inhibitory effect of pentacyclic t...

journal_title：Immunological investigations

authors： Zhou X,Chen H,Wei F,Zhao Q,Su Q,Lei Y,Yin M,Tian X,Liu Z,Yu B,Bai C,He X,Huang Z

更新日期：2020-08-01 00:00:00

abstract：:The relationship between antibody avidity, measured by the dissociation of the antigen-antibody bond in antigen excess, and antibody affinity was studied. Complexes of radiolabelled antigen and antibody of known affinity were prepared in vitro and allowed to stand for seven days to reach equilibrium. Then nonlabelled ...

journal_title：Immunological investigations

authors： Griswold WR

更新日期：1987-04-01 00:00:00

abstract：:A simple and rapid method of ABH phenotyping baboons has been developed which takes advantage of the fact that blood group antigens are expressed on epithelial cells. Use of readily available monoclonal antibodies and phycoerythrin-conjugated second antibody permits rapid identification of ABH phenotypes directly on b...

journal_title：Immunological investigations

authors： Nehlsen-Cannarella SL,Bohn ML

更新日期：1987-03-01 00:00:00

abstract：:Polyclonal immune monkey serum raised against schizonts of Plasmodium knowlesi (H-strain) showed the presence of antibodies to lactate dehydrogenase (LDH) of P. knowlesi by immunodot enzyme staining method. The anti-LDH antibodies are most probably directed towards an epitope distinct from the catalytic site as shown ...

journal_title：Immunological investigations

authors： Kaushal DC,Watts R,Haider S,Singh N,Kaushal NA,Dutta GP

更新日期：1988-08-01 00:00:00

abstract：:Antisera to the chemically synthesized trisaccharide, Gal beta 1-3(GlcNAc beta 1-6)GalNAc, and disaccharide, GlcNAc beta 1-6GalNAc, were developed using the diazophenyl bovine serum albumin derivatives. The binding specificity of the antisera were analyzed by enzyme immunoassays with structurally related, chemically s...

journal_title：Immunological investigations

authors： Matta KL,Piskorz CF,Abbas SA,Diakun KR

更新日期：1991-08-01 00:00:00

abstract：:There is a continuing need for alternatives to current human adjuvants. Recombinant protein vaccines, which target antigen to human Fc gamma receptor type I (hFcgammaRI) on hFcgammaRI-expressing antigen presenting cells, provide one potential alternative. Using a recombinant anti-hFcgammaRI-antigen fusion protein and ...

journal_title：Immunological investigations

authors： Adamova E,Walsh MC,Gosselin DR,Hale K,Preissler MT,Graziano RF,Gosselin EJ

更新日期：2005-01-01 00:00:00