Bromelain inhibits lipopolysaccharide-induced cytokine production in human THP-1 monocytes via the removal of CD14.

abstract：:Mannan binding lectin (MBL) deficiency has been associated with increased susceptibility to vaginitis in humans due to Candida albicans. In these studies we assessed the utility of recombinant human MBL (rhMBL) as a therapeutic against experimental C. albicans vaginitis. After intravenous treatment of uninfected mice ...

journal_title：Immunological investigations

authors： Clemons KV,Martinez M,Axelsen M,Thiel S,Stevens DA

更新日期：2011-01-01 00:00:00

abstract：:Functional defects of polymorphonuclear leukocytes can lead to clinical immunodeficiency. Understanding these conditions requires a knowledge of normal polymorph physiology and the means to analyse various aspects of polymorph function. Primary diseases of polymorph function are rare, whereas disorders secondary to ot...

journal_title：Immunological investigations

authors： Thompson RA

更新日期：1988-04-01 00:00:00

abstract：:Thrombocytopenia as a complicating event in human immunodeficiency infection is a rather common hematological disorder and in many aspects resembles idiopathic(immune) thrombocytopenic purpura (ITP). Consequently, treatment of severe cases is similar to treating ITP, but steroids should be administered with particular...

journal_title：Immunological investigations

authors： Nydegger UE,Castelli D

更新日期：1991-04-01 00:00:00

abstract：:Myeloid derived suppressor cells (MDSCs) are a heterogeneous population of cells that inhibit anti-tumor immunity through a variety of mechanisms. Malignant gliomas are heavily infiltrated by myeloid cells, some of which appear to share biological functions of MDSCs. Our data with mouse de novo gliomas indicate critic...

journal_title：Immunological investigations

authors： Kohanbash G,Okada H

更新日期：2012-01-01 00:00:00

abstract：:For many years, isolation in tissue culture (TC) was considered the test of choice for diagnosis of Chlamydia trachomatis infection. Non-culture tests, such as direct fluorescent antibody (DFA) and enzyme immunoassay (EIA) which detected chlamydial antigens in clinical specimens, made chlamydia diagnostic tests more w...

journal_title：Immunological investigations

authors： Schachter J

更新日期：1997-01-01 00:00:00

abstract：:Anti-IgM stimulation of B cells is decreased in the presence of maternal serum as compared to control media. This inhibiting influence of maternal serum is observed during the priming of the B cells. The progression of B cells into cellular proliferation was not influenced by maternal serum. At the level of the immuno...

journal_title：Immunological investigations

authors： Vanderbeeken YE,Duchateau J,Gregoire M,Vandermeersch B,Collet H,Lucas A

更新日期：1991-06-01 00:00:00

abstract：:Antisera to the chemically synthesized trisaccharide, Gal beta 1-3(GlcNAc beta 1-6)GalNAc, and disaccharide, GlcNAc beta 1-6GalNAc, were developed using the diazophenyl bovine serum albumin derivatives. The binding specificity of the antisera were analyzed by enzyme immunoassays with structurally related, chemically s...

journal_title：Immunological investigations

authors： Matta KL,Piskorz CF,Abbas SA,Diakun KR

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae is a major pathogen accounting for a large number of pneumococcal disease in worldwide. Due to the mucosal immune pathway induces both systemic and mucosal immune responses, the potential strategy to prevent pneumococcal disease may be to develop a mucosal vaccine. METHOD:In this st...

journal_title：Immunological investigations

authors： Wang D,Lu J,Yu J,Hou H,Leenhouts K,Van Roosmalen ML,Gu T,Jiang C,Kong W,Wu Y

更新日期：2018-05-01 00:00:00

abstract：:A group of 11 medicinal plants, including Lavandula pubescens, Trigonella foenugricium, Salsola schweinforthi, Calligonum comosum, Silene succulenta, Silene villosa, Bogonvillea glabra, Cakile maritime, Gomphrene celesoids, Mirabilis jalaba, and Silene nocturna growing in Egypt, were extracted and examined for their i...

journal_title：Immunological investigations

authors： Ghonime M,Emara M,Shawky R,Soliman H,El-Domany R,Abdelaziz A

更新日期：2015-01-01 00:00:00

abstract：:The relationship between antibody avidity, measured by the dissociation of the antigen-antibody bond in antigen excess, and antibody affinity was studied. Complexes of radiolabelled antigen and antibody of known affinity were prepared in vitro and allowed to stand for seven days to reach equilibrium. Then nonlabelled ...

journal_title：Immunological investigations

authors： Griswold WR

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:Diabetic peripheral neuropathy (DPN) is one of late complications of diabetes mellitus. The aim of this study was to evaluate the association between variable number tandem repeat (VNTR) polymorphism in intron 3 of interleukin-4 gene and risk of DPN. METHODS:We examined 926 T2DM patients and 420 healthy cont...

journal_title：Immunological investigations

authors： Buraczynska M,Buraczynska K,Zukowski P,Ksiazek A

更新日期：2018-02-01 00:00:00

abstract：:A simple and rapid method of ABH phenotyping baboons has been developed which takes advantage of the fact that blood group antigens are expressed on epithelial cells. Use of readily available monoclonal antibodies and phycoerythrin-conjugated second antibody permits rapid identification of ABH phenotypes directly on b...

journal_title：Immunological investigations

authors： Nehlsen-Cannarella SL,Bohn ML

更新日期：1987-03-01 00:00:00

abstract：:The rat small intestinal epithelial cell (enterocyte) has an average life span of 48h. Undifferentiated stem cells in the lower crypt region undergo division and differentiation into enterocytes as the cell moves on a basement membrane up the villus to reach the tip and be extruded into the lumen. The mechanism of thi...

journal_title：Immunological investigations

authors： Weiser MM,Ryzowicz S,Soroka CJ,Albini B

更新日期：1989-01-01 00:00:00

abstract：:The susceptibility of cataract Shionogi (CTS) mice as young as 8 to 10 weeks of age to passive anaphylactic shock mediated by anti-benzylpenicilloyl IgE and IgG1 monoclonal antibodies was compared with those of other strains of the same age including sister strains such as nonobese-diabetic (NOD) and nonobese-nondiabe...

journal_title：Immunological investigations

authors： Harada M,Nagata M,Takeuchi M,Makino S,Aburahi S

更新日期：1991-06-01 00:00:00

abstract：:Inoculation of metallic tin powder into Lewis rats resulted in marked enlargement of the draining lymph nodes. Plasma cells were the major contributors to the increase in cell mass. Certain immunologic aspects of this plasma cell lymphadenopathy were investigated. Immunoglobulin isotypes were distinguished and quantit...

journal_title：Immunological investigations

authors： Levine S,Saad A,Rappaport I

更新日期：1987-05-01 00:00:00

abstract：:Cortical (immature) thymocytes are widely reported to express intermediate to high levels of receptors for the lectin, peanut agglutinin (PNA). Light-scatter studies of murine fetal thymocytes stained with PNA or anti-mouse CD4 and CD8 monoclonal antibodies indicated, however, that the most immature CD4-8- (DN) thymoc...

journal_title：Immunological investigations

authors： Holladay S,Blaylock B,Smith B,Luster M

更新日期：1993-12-01 00:00:00

abstract：:Food allergy is an important and common health issue, and there is a need to identify and characterize the sensitizing mechanisms. One of the common causes of food allergy is ovalbumin (OVA), a dietary antigen from eggs. We hypothesized that OVA-induced food allergy in the gut involves the activation of the chemokine ...

journal_title：Immunological investigations

authors： Lee JB,Matsumoto T,Shin YO,Yang HM,Min YK,Timothy O,Bae SJ,Quan FS

更新日期：2004-02-01 00:00:00

abstract：:Identification and characterization of antigenic proteins of Setaria cervi (bovine filarial parasite) adults and microfilariae was done by immunoblotting technique using hyperimmune rabbit sera against S. cervi and Brugia malayi. The antigens recognized by these sera were detected by using 125I protein-A followed by a...

journal_title：Immunological investigations

authors： Kaushal NA,Kaushal DC,Ghatak S

更新日期：1987-04-01 00:00:00

abstract：:The loading of dendritic cells (DCs) with whole tumor cell lysates may circumvent the facts that few tumor-specific antigens have been identified in human solid tumors. The present study was designed to investigate whether ovarian cancer cells lysate-pulsed DCs activate T cell responses against autologous ovarian tumo...

journal_title：Immunological investigations

authors： Zhao X,Wei YQ,Peng ZL

更新日期：2001-02-01 00:00:00

abstract：:Conventional plate ML-ELISA technique for diagnosis of recent cases of amoebiasis was converted into a simple polyvinyl chloride strip multilayer-enzyme linked immunosorbent assay (PVC strip ML-ELISA). This report details the development and preliminary characterization of the PVC strip ML-ELISA method for Entamoeba h...

journal_title：Immunological investigations

authors： Agarwal RK,Rawat R,Malaviya B,Das SR

更新日期：1991-12-01 00:00:00

abstract：:Mast cells have an important role in allergic reactions secreting histamine and other mediators of immediate hypersensitivity. In the present study we evaluated major histocompatibility complex (MHC) class II antigen expression in mast cells and their possible role in antigen presentation. In rats, 10% of mast cells i...

journal_title：Immunological investigations

authors： Banovac K,Neylan D,Leone J,Ghandur-Mnaymneh L,Rabinovitch A

更新日期：1989-08-01 00:00:00

abstract：:The aim of the study was to assess whether genotypes in the Toll-like receptor 4 gene and in the promoter of the interleukin-18 gene are associated with the susceptibility to chronic periodontitis. 108 chronic periodontitis patients and 76 controls were genotyped for c.896A>G/1196C>T (TLR4 gene) and for c.-368G>C/ c.-...

journal_title：Immunological investigations

authors： Noack B,Görgens H,Lorenz K,Schackert HK,Hoffmann T

更新日期：2009-01-01 00:00:00

abstract：:Although cancer immunotherapy, which is able to target specifically cancer cells without detrimental effects to normal cell functions, would serve as an ideal therapeutic modality, most of the randomized clinical trials of cancer immunotherapy have not demonstrated a meaningful survival benefit to cancer patients over...

journal_title：Immunological investigations

authors： Kim SJ,Ha GH,Kim SH,Kang CD

更新日期：2014-01-01 00:00:00

abstract：:Different studies described the antibacterial properties of Lavandula angustifolia (Mill.) essential oil and its anti-inflammatory effects. Besides, no data exist on its ability to activate human macrophages during the innate response against Staphylococcus aureus. The discovery of promising regulators of macrophage-m...

journal_title：Immunological investigations

authors： Giovannini D,Gismondi A,Basso A,Canuti L,Braglia R,Canini A,Mariani F,Cappelli G

更新日期：2016-01-01 00:00:00

abstract：:High altitude may be defined as elevations as low as 1500 meters to those as high as 8800 meters. Very few studies have been conducted so far at high altitude for the specific purpose of monitoring different immune parameters in humans. Military personnel and mountaineers may be required to perform in environmental ex...

journal_title：Immunological investigations

authors： Mishra KP,Ganju L

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are the potential modulators of inflammatory reactions that exert several unique biological effects and could lead to future adverse events of coronary artery disease (CAD). HYPOTHESIS:The purpose of this study was to find out the possible association of modulation in NK cell, TNK ...

journal_title：Immunological investigations

authors： Jabir NR,Firoz CK,Ahmed F,Kamal MA,Hindawi S,Damanhouri GA,Almehdar HA,Tabrez S

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Molecular epidemiological studies have sought associations between interleukin-6 (IL-6) polymorphisms and the risk of systemic lupus erythematosus (SLE); however, the results are controversial. Therefore, we conducted a meta-analysis with trial sequential analysis to evaluate a more accurate estimation of th...

journal_title：Immunological investigations

authors： Liu J,Liao MQ,Cao DF,Yang Y,Yang Y,Liu YH,Zeng FF,Chen XH

更新日期：2021-02-01 00:00:00

abstract：:This study investigated the intestinal anti-inflammatory action of ginsenoside Rf in inflammatory bowel disease (IBD). IBD is a chronic inflammatory disease that affects the intestinal tract. It is associated with elevated levels of various inflammatory mediators, including interleukin (IL)-1β, IL-6, tumor necrosis fa...

journal_title：Immunological investigations

authors： Ahn S,Siddiqi MH,Aceituno VC,Simu SY,Yang DC

更新日期：2016-07-01 00:00:00

abstract：:We investigated the functional and subset surface marker characteristics of supramammary lymph node T cell populations at sites proximal and distal to the mammary region of goats repeatedly injected with heat-treated Staphylococcus aureus antigen (HK-SAC). Flow cytometric studies showed quantitative differences in CD4...

journal_title：Immunological investigations

authors： Dobrzanski MJ,Yang TJ

更新日期：1992-04-01 00:00:00

abstract：:Adenoid hypertrophy is the most common cause of upper airway obstruction and sleep-disordered breathing in children, yet its pathogenesis remains unclear. The identification of the novel helper T cell subsets, Th17 cells and regulatory T cells (Tregs) could provide new insight into our understanding of the mechanisms ...

journal_title：Immunological investigations

authors： Sade K,Fishman G,Kivity S,DeRowe A,Langier S

更新日期：2011-01-01 00:00:00