Immunological aspects of corneal transplant.

abstract：:Factors that suppress natural killer (NK) cell activity were examined in a random sample of 73 schizophrenic patients. NK activity in these patients were compared with 25 healthy age, sex and race matched controls. The mean percent of NK activity was 21% in the schizophrenic group compared with 30% percent in the cont...

journal_title：Immunological investigations

authors： Abdeljaber MH,Nair MP,Schork MA,Schwartz SA

更新日期：1994-08-01 00:00:00

abstract：:Many investigators have demonstrated alteration of gastric mucins in H. pylori infected individuals. The inflammatory environment induced by H. pylori leading to aberrant glycosylation of MUC1 and demasking of core peptide MUC1 epitope could enhance immune responses to MUC1. IgG and IgM immune response to MUC1 in pati...

journal_title：Immunological investigations

authors： Klaamas K,Kurtenkov O,von Mensdorff-Pouilly S,Shljapnikova L,Miljukhina L,Brjalin V,Lipping A

更新日期：2007-01-01 00:00:00

abstract：:In the last 15 years, it has become apparent that ovarian cancer is recognized by the immune system, taking into account that T cell infiltration can be associated with increased overall survival. Several studies indicate that a correct combination of cluster of differentiation 8 and cluster of differentiation 4 T cel...

journal_title：Immunological investigations

authors： Singh M,Loftus T,Webb E,Benencia F

更新日期：2016-11-01 00:00:00

abstract：:The phenomenon of apoptosis observed in lymphoid cells from HIV+ subjects is an important factor contributing to their massive depletion. Several studies have identified nitric oxide (NO) as one of the molecules involved in the apoptosis phenomenon observed during HIV infection. It has been shown that HIV-derived gp12...

journal_title：Immunological investigations

authors： García M,del Llano AM,Cruz-Colón E,Saavedra S,Lavergne JA

更新日期：2001-11-01 00:00:00

abstract：:Background: Polymorphisms in T-cell immunoglobulin and mucin domain 3 (TIM-3) gene have been implicated in susceptibility to autoimmune diseases (ADs) with inconsistent results. The aim of this study was to perform meta-analyses for clarifying the relationship between them. Methods: All relevant case-control studies w...

journal_title：Immunological investigations

authors： Zhang R,Li H,Bai L,Duan J

更新日期：2019-08-01 00:00:00

abstract：:Champedak (Artocarpus integer) lectin-M is a lectin with high specificity and affinity for the core-mannosyl residues of the N-linked oligosaccharides of glycoproteins. We have studied the interaction of the champedak seed lectin with human serum glycoproteins that were resolved by 2-dimensional (2-D) gel electrophore...

journal_title：Immunological investigations

authors： Hashim OH,Ahmad F,Shuib AS

更新日期：2001-05-01 00:00:00

abstract：:In the present study, we evaluated two novel technologies, the chemiluminescent immunoassay (CIA) QUANTA Flash on BIO-FLASH (Inova Diagnostics, San Diego, CA, USA) and the addressable laser bead immunoassay (ALBIA) on BioPlex™ 2200 (Bio-Rad, Hercules, CA, USA) for the detection of anti-cardiolipin IgG/IgM (aCL) and an...

journal_title：Immunological investigations

authors： Grossi V,Infantino M,Benucci M,Li Gobbi F,Bandinelli F,Damiani A,Bodio C,Borghi MO,Mahler M,Aure MA,Bentow C,Manfredi M

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:This study aimed to examine the association of three functional IRF5 rs10954213, rs3757385, and rs41298401 polymorphisms with susceptibility to unexplained recurrent pregnancy loss (RPL) among Iranian women from south of Iran. METHODS:176 women with unexplained RPL and 173 healthy postmenopausal controls wer...

journal_title：Immunological investigations

authors： Amiri Jahromi R,Nasiri M,Jahromi AR

更新日期：2017-01-01 00:00:00

abstract：:Mannan binding lectin (MBL) deficiency has been associated with increased susceptibility to vaginitis in humans due to Candida albicans. In these studies we assessed the utility of recombinant human MBL (rhMBL) as a therapeutic against experimental C. albicans vaginitis. After intravenous treatment of uninfected mice ...

journal_title：Immunological investigations

authors： Clemons KV,Martinez M,Axelsen M,Thiel S,Stevens DA

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Molecular epidemiological studies have sought associations between interleukin-6 (IL-6) polymorphisms and the risk of systemic lupus erythematosus (SLE); however, the results are controversial. Therefore, we conducted a meta-analysis with trial sequential analysis to evaluate a more accurate estimation of th...

journal_title：Immunological investigations

authors： Liu J,Liao MQ,Cao DF,Yang Y,Yang Y,Liu YH,Zeng FF,Chen XH

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To study the relation between CD226 rs763361 gene polymorphism and CD226 serum level and to evaluate their role in susceptibility and disease activity of RA in a cohort of Egyptian individuals. METHODS:The serum level of CD226 was measured using a suitable ELISA kit and the CD226 rs763361 gene polymorphism w...

journal_title：Immunological investigations

authors： Mosaad YM,El-Toraby EE,Tawhid ZM,Abdelsalam AI,Enin AF,Hasson AM,Shafeek GM

更新日期：2018-04-01 00:00:00

abstract：:Electroeluted outer membrane proteins [(EOmp), (35-37 KDa, porins)] were highly immunogenic in New Zealand White rabbits. An ELISA peak titer of 51,200 to EOmp as compared to 6,400 for non-eluted outer membrane protein (Omp) was demonstrated. EOmp enhanced the antigenicity of Omp possibly due to epitopes which were ma...

journal_title：Immunological investigations

authors： Kawahara M,Human LG,Kawahara K,Domingue GJ

更新日期：1994-04-01 00:00:00

abstract：:This preliminary study examined the effects of immunization with Bacteroides macacae, the monkey equivalent of the human species of B. gingivalis on ligature-induced periodontitis. During a 12 week immunization period, 8 out of the 12 Macacae fasicularis monkeys were immunized weekly with B. macacae washed cells and 4...

journal_title：Immunological investigations

authors： Nisengard R,Blann D,Zelonis L,McHenry K,Reynolds H,Zambon J

更新日期：1989-01-01 00:00:00

abstract：:In a previous study, we noticed that some ascitic cells isolated from melanoma patients survive, proliferate, and differentiate into giant phagocytes after the other cells died. Similar phenomena were observed in the primary cultures of mouse lung and liver cells. In the present study, the effects of dying cells on ab...

journal_title：Immunological investigations

authors： Yuan X,Li X,Zhang Q,Zhang C,Yang Z,Li D

更新日期：2013-01-01 00:00:00

abstract：:Regulatory T cells (Tregs) play pivotal roles in limiting the duration and magnitude of immune response against infectious agents and self-antigens. This is accomplished through contact-dependent and -independent mechanisms that involve crosstalk between Treg cells and other immune and tissue-specific cell types. The ...

journal_title：Immunological investigations

authors： Wang K,Vella AT

更新日期：2016-11-01 00:00:00

abstract：:Previous work had implicated T cells within the stimulating population as having a significant role in the MLR. We now report that depletion of T cells from the stimulators caused a reduction in proliferative response in mixed leukocyte reaction (MLR) by 50% or more. This response could be restored by adding T-enriche...

journal_title：Immunological investigations

authors： Roy C,Brown DL,Kaplan JG

更新日期：1986-03-01 00:00:00

abstract：:Anti-IgM stimulation of B cells is decreased in the presence of maternal serum as compared to control media. This inhibiting influence of maternal serum is observed during the priming of the B cells. The progression of B cells into cellular proliferation was not influenced by maternal serum. At the level of the immuno...

journal_title：Immunological investigations

authors： Vanderbeeken YE,Duchateau J,Gregoire M,Vandermeersch B,Collet H,Lucas A

更新日期：1991-06-01 00:00:00

abstract：:Antisera to the chemically synthesized trisaccharide, Gal beta 1-3(GlcNAc beta 1-6)GalNAc, and disaccharide, GlcNAc beta 1-6GalNAc, were developed using the diazophenyl bovine serum albumin derivatives. The binding specificity of the antisera were analyzed by enzyme immunoassays with structurally related, chemically s...

journal_title：Immunological investigations

authors： Matta KL,Piskorz CF,Abbas SA,Diakun KR

更新日期：1991-08-01 00:00:00

abstract：:To investigate whether phospholipase D1 (PLD1) is involved in autoimmune damage to the eyes, we used Western blotting and immunohistochemistry to examine the expression and distribution of PLD1 in the retinas of Lewis rats with experimental autoimmune uveoretinitis (EAU). Western blot analysis showed that the level of...

journal_title：Immunological investigations

authors： Kang J,Ahn M,Moon C,Min DS,Matsumoto Y,Shin T

更新日期：2005-01-01 00:00:00

abstract：:There is a continuing need for alternatives to current human adjuvants. Recombinant protein vaccines, which target antigen to human Fc gamma receptor type I (hFcgammaRI) on hFcgammaRI-expressing antigen presenting cells, provide one potential alternative. Using a recombinant anti-hFcgammaRI-antigen fusion protein and ...

journal_title：Immunological investigations

authors： Adamova E,Walsh MC,Gosselin DR,Hale K,Preissler MT,Graziano RF,Gosselin EJ

更新日期：2005-01-01 00:00:00

abstract：:The critical contribution of CD4+CD25+Foxp3+ T-regulatory cells (Treg) to immune suppression in the tumor microenvironment is well-established. Whereas the mechanisms that drive the generation and accumulation of Treg in tumors have been an active area of study, the information on their origin and population dynamics ...

journal_title：Immunological investigations

authors： Li Q,Egilmez NK

更新日期：2016-11-01 00:00:00

abstract：:Whole-body hyperthermia (WBH) has been used as an adjunct approach to radio-/ chemotherapy for tumor therapy for many years. However, the molecular mechanism underlying the enhancement of tumor control is not clearly understood. It has been hypothesized that WBH might activate immune system by inducing the expression ...

journal_title：Immunological investigations

authors： Zhang H,Wang W,Zhang S,Huang W

更新日期：2005-01-01 00:00:00

abstract：:Cortical (immature) thymocytes are widely reported to express intermediate to high levels of receptors for the lectin, peanut agglutinin (PNA). Light-scatter studies of murine fetal thymocytes stained with PNA or anti-mouse CD4 and CD8 monoclonal antibodies indicated, however, that the most immature CD4-8- (DN) thymoc...

journal_title：Immunological investigations

authors： Holladay S,Blaylock B,Smith B,Luster M

更新日期：1993-12-01 00:00:00

abstract：PURPOSE:To assess cellular composition and local cytokine response in vitreous humor of tubercular uveitis. METHODS:Cells were collected from vitreous cassettes and peripheral blood of 8 tubercular uveitis and 5 control subjects, undergoing vitrectomy and analyzed by flow cytometry for cellular composition, activation...

journal_title：Immunological investigations

authors： Sharma RK M.Sc,Gupta V M.S,Bansal R M.S,Sharma K M.D,Gupta A M.S,Sachdeva N Ph.D

更新日期：2018-08-01 00:00:00

abstract：:The bacterial superantigen Staphylococcal enterotoxin-A (SEA), produced by some strains of Staphylococcus aureus, causes proliferation of cytotoxic T-lymphocytes and cytokine production in vivo. SEA has been shown to be highly efficient for antibody-targeted superantegen immunotherapy for different tumor models. A can...

journal_title：Immunological investigations

authors： Mondal TK,Bhatta D,Biswas S,Pal P

更新日期：2002-02-01 00:00:00

abstract：:There has been a dramatic increase recently in the number of reports of septic episodes associated with both red cell and platelet concentrate transfusions. These reports suggest that transfusion-associated septic reactions may occur as often as 1 per 4000 platelet transfusions, however, the true incidence of the bact...

journal_title：Immunological investigations

authors： Blajchman MA

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Rheumatic fever (RF) and its sequel rheumatic heart disease (RHD) is an autoimmune disease caused by an abnormal host immune response to group A streptococcus (GAS) infection. The HLA class II molecules are entailed in immune-mediated infectious, inflammatory, and autoimmune diseases including RHD. However, ...

journal_title：Immunological investigations

authors： Poomarimuthu M,Ramasamy T,Govindan R,Andiappan R,Nagarajan G,Kadiam S,Mariakuttikan J

更新日期：2020-09-23 00:00:00

abstract：:We report a method combining mixed lymphocyte reaction (MLR) using a carboxyfluorescein diacetate succinimidyl ester (CFSE)-labeling technique, intracellular cytokine immunofluorescence staining (ICIS), and multiparameter flow cytometry for simultaneous determination of proliferation and cytokine-secreting activity in...

journal_title：Immunological investigations

authors： Tanaka Y,Ohdan H,Onoe T,Asahara T

更新日期：2004-08-01 00:00:00

abstract：:The processing of antigenic peptides for presentation by MHC molecules to T cells, may depend upon the function of a second, consensus sequence in or near the T cell-presented epitope. One such processing-regulating sequence appears to be composed of amino acids Leu, Ile, Val, Phe, and Met recurring in a fashion to fo...

journal_title：Immunological investigations

authors： Goldschmidt TG,Reyes VE,You G,Nelson DJ,Reisert PS,Anderson J,Mole J,Humphreys RE

更新日期：1993-02-01 00:00:00

abstract：:White cell infiltration of solid tumors is an important prognostic indicator in malignant disease. Although macrophage infiltration is associated with good outcome in colorectal cancer, a high macrophage content is associated with poor prognosis in breast cancer. Suppressor macrophages prevent T cell activation in nor...

journal_title：Immunological investigations

authors： Toomey D,Harmey J,Condron C,Kay E,Bouchier-Hayes D

更新日期：1999-01-01 00:00:00