Bacterial contamination of blood products and the value of pre-transfusion testing.

abstract：:Hepatitis C virus (HCV), a major cause of liver disease worldwide, is frequently resistant to the antiviral alpha interferon (IFN). Previous studies have shown that HCV NS5A protein induces expression of the proinflammatory interleukin-8 (IL-8) and this may affect the therapeutic outcome. The aim of the present study ...

journal_title：Immunological investigations

authors： El Sayed ZM,Mansour FA,Ghal MF,Abou-Zahra SB

更新日期：2011-01-01 00:00:00

abstract：:This study was conducted to evaluate the adjuvant potential of sulfated Radix Cyathulae officinalis Kuan polysaccharides (sRCPS) and their effects on specific cellular and humoral immune responses to hepatitis B subunit vaccine in mice. Our data demonstrated that sRCPS significantly promoted the rHBsAg-specific IgG, I...

journal_title：Immunological investigations

authors： Feng H,Fan J,Du X,Song Z,Wang Z,Han X,Zhao B,Liu J

更新日期：2015-01-01 00:00:00

abstract：:This preliminary study examined the effects of immunization with Bacteroides macacae, the monkey equivalent of the human species of B. gingivalis on ligature-induced periodontitis. During a 12 week immunization period, 8 out of the 12 Macacae fasicularis monkeys were immunized weekly with B. macacae washed cells and 4...

journal_title：Immunological investigations

authors： Nisengard R,Blann D,Zelonis L,McHenry K,Reynolds H,Zambon J

更新日期：1989-01-01 00:00:00

abstract：:Rotaviruses were first recognized about 15 years ago in association with diarrhea in children and animals. Since then, rotaviruses have been determined to be the most important viral agent that causes clinically significant diarrhea in children and a need for an effective vaccination program has been recognized. This ...

journal_title：Immunological investigations

authors： Estes MK,Conner ME,Gilger MA,Graham DY

更新日期：1989-01-01 00:00:00

abstract：:Although cancer immunotherapy, which is able to target specifically cancer cells without detrimental effects to normal cell functions, would serve as an ideal therapeutic modality, most of the randomized clinical trials of cancer immunotherapy have not demonstrated a meaningful survival benefit to cancer patients over...

journal_title：Immunological investigations

authors： Kim SJ,Ha GH,Kim SH,Kang CD

更新日期：2014-01-01 00:00:00

abstract：:Implantation of pellets containing 75 mg of morphine induced short term (4 day) morphine dependence and markedly reduced total number of spleen cells of BALB/c mice, without affecting total body or liver weight. Polyclonal responses induced by anti-CD3 antibodies, Concanavalin A or Escherichia coli lipopolysaccharide ...

journal_title：Immunological investigations

authors： Portolés JM,Ojeda G,Ronda M,Leza JC,Rojo JM

更新日期：1995-05-01 00:00:00

abstract：:Flow cytometric analyses of immune cell proliferation, differentiation, and function are limited by the number of different fluorochromes that can be resolved simultaneously. Additional colors to expand functional analytic capability will facilitate higher dimensional analyses of heterogeneous cell populations by basi...

journal_title：Immunological investigations

authors： Bantly AD,Gray BD,Breslin E,Weinstein EG,Muirhead KA,Ohlsson-Wilhelm BM,Moore JS

更新日期：2007-01-01 00:00:00

abstract：:Experimental autoimmune uveoretinitis (EAU) was induced in rats by immunization with bovine interphotoreceptor retinoid-binding protein (IRBP) and studied by immunohistochemistry. In general, the IRBP induction of inflammatory cellular components and expression of immune-related antigens on various non-lymphoid cells ...

journal_title：Immunological investigations

authors： Chan CC,Nussenblatt RB,Wiggert B,Redmond TM,Fujikawa LS,Chader GJ,Gery I

更新日期：1987-03-01 00:00:00

abstract：:Adenoid hypertrophy is the most common cause of upper airway obstruction and sleep-disordered breathing in children, yet its pathogenesis remains unclear. The identification of the novel helper T cell subsets, Th17 cells and regulatory T cells (Tregs) could provide new insight into our understanding of the mechanisms ...

journal_title：Immunological investigations

authors： Sade K,Fishman G,Kivity S,DeRowe A,Langier S

更新日期：2011-01-01 00:00:00

abstract：:A simple and rapid method of ABH phenotyping baboons has been developed which takes advantage of the fact that blood group antigens are expressed on epithelial cells. Use of readily available monoclonal antibodies and phycoerythrin-conjugated second antibody permits rapid identification of ABH phenotypes directly on b...

journal_title：Immunological investigations

authors： Nehlsen-Cannarella SL,Bohn ML

更新日期：1987-03-01 00:00:00

abstract：:We have examined the effect which xenogeneic anti-Ig has on rabbit B cell function and Ig expression in an effort to understand the phenomenon of antibody mediated suppression. Treatment of rabbit lymphocyte cultures with xenogeneic anti-rabbit Ig causes 2.5-3.8 fold decrease in the level of Ig secreting cells with li...

journal_title：Immunological investigations

authors： Ives N,Asundi V,Dreher K

更新日期：1991-02-01 00:00:00

abstract：:We report a method combining mixed lymphocyte reaction (MLR) using a carboxyfluorescein diacetate succinimidyl ester (CFSE)-labeling technique, intracellular cytokine immunofluorescence staining (ICIS), and multiparameter flow cytometry for simultaneous determination of proliferation and cytokine-secreting activity in...

journal_title：Immunological investigations

authors： Tanaka Y,Ohdan H,Onoe T,Asahara T

更新日期：2004-08-01 00:00:00

abstract：:Lymphotoxin beta receptor (LTBR) is essential for development and organization of the secondary lymphoid tissues. To investigate whether LTBR polymorphisms are associated with IgA nephropathy (IgAN) in Korean children, One hundred ninety nine patients with IgAN and 289 controls were recruited. Two promoter single nucl...

journal_title：Immunological investigations

authors： Kim SK,Lee JY,Jeong Park H,Chung JH,Suh JS,Hahn WH,Cho BS,Kim MJ

更新日期：2012-01-01 00:00:00

abstract：:The cardinal features of asthma include pulmonary inflammation and airway hyperresponsiveness (AHR). Classically, asthma, specifically allergic asthma, has been attributed to a hyperactive Th2 cell immune response. However, the Th2 cell-mediated inflammation model has failed to adequately explain many of the clinical ...

journal_title：Immunological investigations

authors： Durrant DM,Metzger DW

更新日期：2010-01-01 00:00:00

abstract：:Mannan binding lectin (MBL) deficiency has been associated with increased susceptibility to vaginitis in humans due to Candida albicans. In these studies we assessed the utility of recombinant human MBL (rhMBL) as a therapeutic against experimental C. albicans vaginitis. After intravenous treatment of uninfected mice ...

journal_title：Immunological investigations

authors： Clemons KV,Martinez M,Axelsen M,Thiel S,Stevens DA

更新日期：2011-01-01 00:00:00

abstract：:Seven commercially available intravenous immunoglobulins (IVIG) preparations, a gamma globulin prepared by ethanol fractionation, and an experimental IgG isolated by a chromatographic procedure were compared in several tests. Split products were present in preparations manufactured by procedures involving protease tre...

journal_title：Immunological investigations

authors： Medgyesi GA,Kovács J,Füst G,Merétey K

更新日期：1988-04-01 00:00:00

abstract：:Bromelain has been reported to have anti-inflammatory and immunomodulatory effects. However, the anti-inflammatory mechanism of bromelain is unclear. Therefore, we investigated the effect of bromelain on cytokine production from lipopolysaccharide (LPS)-stimulated human peripheral blood mononuclear cells (PBMC) and mo...

journal_title：Immunological investigations

authors： Huang JR,Wu CC,Hou RC,Jeng KC

更新日期：2008-01-01 00:00:00

abstract：:The lectin from Amaranthus leucocarpus (ALL) is specific for N-acetyl-D-galactosamine and inhibits phagocytosis of Leishmania mexicana promastigotes in Balb/c mice peritoneal macrophages by 38%. The lipophosphoglycan (LPG) purified from L. mexicana inhibits penetration of promastigotes into peritoneal macrophages by 3...

journal_title：Immunological investigations

authors： Gorocica P,Hernández P,Perez A,Chávez R,Baez R,Zenteno E,Lascurain R

更新日期：2000-11-01 00:00:00

abstract：:Conjugated linoleic acid (CLA) is a dietary fatty acid which causes extensive remodeling and mast cell recruitment in the mouse mammary gland. Two CLA isomers, 9,11- and 10,12-CLA, have differing effects in vivo, with only 10,12-CLA increasing mast cell number. The purpose of this project is to test the hypothesis tha...

journal_title：Immunological investigations

authors： Krishnan S,Russell J,Bodziak M,Koury S,Masso-Welch P

更新日期：2012-01-01 00:00:00

abstract：:To investigate whether phospholipase D1 (PLD1) is involved in autoimmune damage to the eyes, we used Western blotting and immunohistochemistry to examine the expression and distribution of PLD1 in the retinas of Lewis rats with experimental autoimmune uveoretinitis (EAU). Western blot analysis showed that the level of...

journal_title：Immunological investigations

authors： Kang J,Ahn M,Moon C,Min DS,Matsumoto Y,Shin T

更新日期：2005-01-01 00:00:00

abstract：:Many investigators have demonstrated alteration of gastric mucins in H. pylori infected individuals. The inflammatory environment induced by H. pylori leading to aberrant glycosylation of MUC1 and demasking of core peptide MUC1 epitope could enhance immune responses to MUC1. IgG and IgM immune response to MUC1 in pati...

journal_title：Immunological investigations

authors： Klaamas K,Kurtenkov O,von Mensdorff-Pouilly S,Shljapnikova L,Miljukhina L,Brjalin V,Lipping A

更新日期：2007-01-01 00:00:00

abstract：:This research was undertaken to test the in vitro anti-inflammatory action of 5,7,4'-trimethoxy-4-phenylcoumarin and 5,7-dimethoxy-4-phenylcoumarin produced by Streptomyces aureofaciens CMUAc130. The effects of the two coumarins were investigated on the formation of NO, PGE2, and TNF-alpha and also on inducible nitric...

journal_title：Immunological investigations

authors： Taechowisan T,Tuntiwachwuttikul P,Lu C,Shen Y,Lumyong S,Taylor WC

更新日期：2007-01-01 00:00:00

abstract：:Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder caused by genetic, environmental and immunological factors. It is known that neural development processes are affected by immune functions. The aim of this study is to evaluate the relationship between cytokines IL6 and IL1B gene polymorphisms...

journal_title：Immunological investigations

authors： Pekkoc Uyanik KC,Kalayci Yigin A,Dogangun B,Seven M

更新日期：2021-01-12 00:00:00

abstract：:Plasmodium falciparum CTL epitope minigenes containing HLA-A2 and HLA-B7 subtype supermotifs were cloned into a plasmid expression vector; this expression was measured in eight human HLA class I molecule specific cell lines. Three assays for in vitro antigen presentation analysis were developed to examine the cross-bi...

journal_title：Immunological investigations

authors： Tang Y,Lin Y,Mao Y,Dong M,Wang H

更新日期：2003-02-01 00:00:00

abstract：:Genome-wide association studies have led to the discovery of several susceptibility genes related to autoimmune thyroid diseases (AITDs). However, controversial results have been reported regarding the role of single-nucleotide polymorphism (SNP) of CD40 in the disease susceptibility. The objective of this study was t...

journal_title：Immunological investigations

authors： Wang D,Chen J,Zhang H,Zhang F,Yang L,Mou Y

更新日期：2017-08-01 00:00:00

abstract：:Champedak (Artocarpus integer) lectin-M is a lectin with high specificity and affinity for the core-mannosyl residues of the N-linked oligosaccharides of glycoproteins. We have studied the interaction of the champedak seed lectin with human serum glycoproteins that were resolved by 2-dimensional (2-D) gel electrophore...

journal_title：Immunological investigations

authors： Hashim OH,Ahmad F,Shuib AS

更新日期：2001-05-01 00:00:00

abstract：:In the last 10 years many of the superantigens of the microbial world have been defined and the mechanisms of cellular interaction between lymphocytes and antigen presenting cells has been elucidated in great detail. The consequences of superantigen stimulation of the immune system, though less well defined, can be co...

journal_title：Immunological investigations

authors： Stevens DL

更新日期：1997-01-01 00:00:00

abstract：:Adjuvant interleukin (IL)-2 immunotherapy has been used in the treatment of different malignant dieseases. However, clinical results have been rather disappointing. Therefore, further investigations on IL-2-induced mediators of cytotoxicity seem to be necessary in order to possibly create cytokine cocktails which coul...

journal_title：Immunological investigations

authors： Mauz-Körholz C,Banning U,Körholz D

更新日期：2004-05-01 00:00:00

abstract：:Myeloid derived suppressor cells (MDSCs) are a heterogeneous population of cells that inhibit anti-tumor immunity through a variety of mechanisms. Malignant gliomas are heavily infiltrated by myeloid cells, some of which appear to share biological functions of MDSCs. Our data with mouse de novo gliomas indicate critic...

journal_title：Immunological investigations

authors： Kohanbash G,Okada H

更新日期：2012-01-01 00:00:00

abstract：:In a previous study, we noticed that some ascitic cells isolated from melanoma patients survive, proliferate, and differentiate into giant phagocytes after the other cells died. Similar phenomena were observed in the primary cultures of mouse lung and liver cells. In the present study, the effects of dying cells on ab...

journal_title：Immunological investigations

authors： Yuan X,Li X,Zhang Q,Zhang C,Yang Z,Li D

更新日期：2013-01-01 00:00:00