Association of Interleukin-23R Gene Polymorphisms with Behcet's Disease Susceptibility: A Meta-Analysis of Case-control Studies.

abstract：:A rapid, quantitative enzyme-linked immunosorbent assay (ELISA) for the immunodiagnosis of Chagas' disease is described. The ELISA was standardized with the Falcon assay screening test (F.A.S.T.) system using a purified Trypanosoma cruzi epimastigote fraction (PEF) obtained by ion exchange chromatography. The ELISA te...

journal_title：Immunological investigations

authors： Partel CD,Rossi CL

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae is a major pathogen accounting for a large number of pneumococcal disease in worldwide. Due to the mucosal immune pathway induces both systemic and mucosal immune responses, the potential strategy to prevent pneumococcal disease may be to develop a mucosal vaccine. METHOD:In this st...

journal_title：Immunological investigations

authors： Wang D,Lu J,Yu J,Hou H,Leenhouts K,Van Roosmalen ML,Gu T,Jiang C,Kong W,Wu Y

更新日期：2018-05-01 00:00:00

abstract：:Intravenous immunoglobulins (IVIg) have been used as an immunomodulatory therapy in a variety of diseases. Several mechanisms of action have been proposed, one of which is interference with the cytokine network. We have investigated the effect of IVIg on the cytotoxicity of human TNF alpha. IVIg was capable of protect...

journal_title：Immunological investigations

authors： Stangel M,Schumacher HC,Ruprecht K,Boegner F,Marx P

更新日期：1997-08-01 00:00:00

abstract：:Studies demonstrated that deficiency in 17β-estradiol (E2) in postmenopausal women influences their immune system. However, few studies have reported alterations in immunologic presentation during nonnatural menopause in young females. Here we compared the differences in immune response between young C57BL/6N mice wit...

journal_title：Immunological investigations

authors： Shao MJ,Zhu YJ,Qiu YE,Hu M,He YQ

更新日期：2017-04-01 00:00:00

abstract：:Myeloid derived suppressor cells (MDSCs) are a heterogeneous population of cells that inhibit anti-tumor immunity through a variety of mechanisms. Malignant gliomas are heavily infiltrated by myeloid cells, some of which appear to share biological functions of MDSCs. Our data with mouse de novo gliomas indicate critic...

journal_title：Immunological investigations

authors： Kohanbash G,Okada H

更新日期：2012-01-01 00:00:00

abstract：:A. actinomycetemcomitans is a facultative Gram-negative coccobacillus which has been implicated in the etiology and pathogenesis of localized juvenile periodontitis and has also been recognized for its potential to cause serious extraoral infections, particularly endocarditis. The polymorphonuclear neutrophil has been...

journal_title：Immunological investigations

authors： Wilson ME,Genco RJ

更新日期：1989-01-01 00:00:00

abstract：:Objectives: Ataxia-telangiectasia (A-T) is an autosomal recessive neurodegenerative disorder with multisystem involvement caused by homozygous or compound heterozygous mutations in the ataxia telangiectasia mutated (ATM) gene which encodes a serine/threonine protein kinase. The aims of this study were to investigate c...

journal_title：Immunological investigations

authors： Amirifar P,Mozdarani H,Yazdani R,Kiaei F,Moeini Shad T,Shahkarami S,Abolhassani H,Delavari S,Sohani M,Rezaei A,Hassanpour G,Akrami SM,Aghamohammadi A

更新日期：2021-02-01 00:00:00

abstract：:An enzyme-linked immunoassay (EIA) is described and evaluated which quantitates human antibodies to serotype specific S. pneumoniae polysaccharide (PnPs) in human sera. Based on the observations previously described by Koskela (1), native PnPs are used as coating antigens and sera are absorbed with a soluble pneumococ...

journal_title：Immunological investigations

authors： Quataert S,Martin D,Anderson P,Giebink GS,Henrichsen J,Leinonen M,Granoff DM,Russell H,Siber G,Faden H,Barnes D,Madore DV

更新日期：2001-08-01 00:00:00

abstract：:DNA vaccine represents a powerful approach for prevention of avian H5N1 influenza infection. Yet, DNA vaccine-induced immune responses might be limited by the short duration of antigen expression. As a strategy to enhance adaptive immune responses elicited by a hemagglutinin 5 (H5) DNA vaccine, we explored the effect ...

journal_title：Immunological investigations

authors： Tabatabaeizadeh SE,Bassami MR,Haghparast A,Dehghani H

更新日期：2015-01-01 00:00:00

abstract：:Previous work had implicated T cells within the stimulating population as having a significant role in the MLR. We now report that depletion of T cells from the stimulators caused a reduction in proliferative response in mixed leukocyte reaction (MLR) by 50% or more. This response could be restored by adding T-enriche...

journal_title：Immunological investigations

authors： Roy C,Brown DL,Kaplan JG

更新日期：1986-03-01 00:00:00

abstract：:For many years, isolation in tissue culture (TC) was considered the test of choice for diagnosis of Chlamydia trachomatis infection. Non-culture tests, such as direct fluorescent antibody (DFA) and enzyme immunoassay (EIA) which detected chlamydial antigens in clinical specimens, made chlamydia diagnostic tests more w...

journal_title：Immunological investigations

authors： Schachter J

更新日期：1997-01-01 00:00:00

abstract：:Interleukin-31 (IL-31) has diverse biological functions. Increased IL-31 has been found in some skin and autoimmune diseases. There has been no study reporting the association between IL-31 and primary biliary cholangitis (PBC). This study was designed to determine serum IL-31 level and to explore its diagnostic value...

journal_title：Immunological investigations

authors： Mu N,Lin F,Jiang Z,Liang Y,Yang Z

更新日期：2020-07-02 00:00:00

abstract：:Functional defects of polymorphonuclear leukocytes can lead to clinical immunodeficiency. Understanding these conditions requires a knowledge of normal polymorph physiology and the means to analyse various aspects of polymorph function. Primary diseases of polymorph function are rare, whereas disorders secondary to ot...

journal_title：Immunological investigations

authors： Thompson RA

更新日期：1988-04-01 00:00:00

abstract：:Rapid and accurate diagnosis of cytomegalovirus (CMV) infection is imperative with the advent of effective antiviral therapy (gangiclovir, foscarnet, CMV hyperimmune globin). Applications of conventional cell culture (CC), shell vial assay (SV), serological testing, antigenemia assay (AG) as well as molecular methods ...

journal_title：Immunological investigations

authors： Myers JB,Amsterdam D

更新日期：1997-04-01 00:00:00

abstract：:Porphyromonas gingivalis (P.g) is the primary bacterial agent in many forms of chronic periodontitis. Since polymorphonuclear leukocytes (PMNs) are first-line responders to P.g.- induced inflammation, and fibrinogen is important for in vivo PMN in this disease, we have studied the effect of N-formyl-methionyl-leucyl-p...

journal_title：Immunological investigations

authors： Sahingur SE,Boehm TK,Sojar HT,Sharma A,De Nardin E

更新日期：2006-01-01 00:00:00

abstract：:The central dogma of gene therapy relies on the application of novel therapeutic genes to treat or prevent diseases. The main types of vectors used for gene transfer are adenovirus, retrovirus, lentivirus, liposome, and adeno-associated virus vectors. Gene therapy has emerged as a promising alternative for the treatme...

journal_title：Immunological investigations

authors： Castañeda-Lopez ME,Garza-Veloz I,Lopez-Hernandez Y,Barbosa-Cisneros OY,Martinez-Fierro ML

更新日期：2016-07-01 00:00:00

abstract：:Patients with metastatic breast carcinoma (BCa) have defective peripheral blood lymphocyte (PBL) responsiveness to mitogenic and antigenic stimulation. In the following experiments, glycopeptides were isolated from the pronase digests of breast carcinoma tissue. After elution from Sephadex G-50, glycopeptides from BCa...

journal_title：Immunological investigations

authors： Dube VE,Kallio P,Hakim A

更新日期：1988-03-01 00:00:00

abstract：:Spleen cells of C57BL/6 mice injected with corticosterone were compared with cells from mice injected with saline in their ability to respond to the mitogens PHA, Con A, and LPS. Both unseparated cells and cells separated into T-enriched and B-enriched fractions were studied. After either seven daily injections or fou...

journal_title：Immunological investigations

authors： Stevenson JR,Kreiling JA,Taylor R

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Cancer immunotherapies have achieved much success and have become the forefront treatment of cancers previously associated with poor prognosis. However, a major challenge in cancer immunotherapies remains the heterogeneity of the immunoregulatory capacities of cancers, and not all patients of a given cancer ...

journal_title：Immunological investigations

authors： Andersen MM,Larsen J,Hansen M,Pedersen AE,Gad M

更新日期：2020-06-23 00:00:00

abstract：:Prolonged survival of C57BL/6 (B6) mice bearing syngenic EL-4 leukemia cells resulted from immunization with irradiated EL-4 cells on the day of inoculation of live leukemia cells. No prolongation of survival was observed if the irradiated cells were injected 6 or 13 days after live cell inoculation. Protection also w...

journal_title：Immunological investigations

authors： Abeyounis CJ,Bekierkunst A,Milgrom F

更新日期：1985-12-01 00:00:00

abstract：:The objective of this study was to analyze how Staphylococcus epidermidis SCV and WT strains manipulate the PI3K/Akt/mTOR signaling pathway. Six S. epidermidis strains with normal phenotype (WT) and six S. epidermidis strains with SCV phenotype were isolated in parallel from six patients with the prosthetic hip joint ...

journal_title：Immunological investigations

authors： Magryś A,Bogut A,Kiełbus M,Olender A

更新日期：2018-04-01 00:00:00

abstract：:In recent studies, using a swine model of single lung transplantation, we demonstrated that IRI alone increased MHC II expression in the host's peripheral T lymphocytes. The inhibition of increased MHC II expression with TCV-309, a specific platelet-activating factor (PAF) antagonist suggested that PAF might play a ro...

journal_title：Immunological investigations

authors： Nikbakht-Sangari M,Qayumi AK,Keown P,Duronio V,Horley K

更新日期：1999-07-01 00:00:00

abstract：:High altitude may be defined as elevations as low as 1500 meters to those as high as 8800 meters. Very few studies have been conducted so far at high altitude for the specific purpose of monitoring different immune parameters in humans. Military personnel and mountaineers may be required to perform in environmental ex...

journal_title：Immunological investigations

authors： Mishra KP,Ganju L

更新日期：2010-01-01 00:00:00

abstract：:A colorimetric microadhesion assay that allows the quantitative determination of carcinoembryonic antigen (CEA)-mediated homophilic cell adhesion to CEA immobilized on 96-well polyvinyl chloride plates is described. Chinese hamster ovary (CHO) cells transfected with a full-length CEA cDNA were used as indicator cells....

journal_title：Immunological investigations

authors： Kuwahara M,Kuroki M,Haruno M,Murakami M,Arakawa F,Oikawa S,Nakazato H,Matsuoka Y

更新日期：1994-11-01 00:00:00

abstract：:VH4-34 gene encoded autoantibodies are elevated in systemic lupus erythematosus (SLE) and in other diseases associated with B-cell hyperproliferation/dysfunction. One of the autoantigens recognized by VH4-34-encoded antibodies are branched/linear poly N-acetyl lactosamine chains. Since the anti-carbohydrate response i...

journal_title：Immunological investigations

authors： Bhat NM,Kshirsagar MA,Bieber MM,Teng NN

更新日期：2015-01-01 00:00:00

abstract：:Plasmodium falciparum CTL epitope minigenes containing HLA-A2 and HLA-B7 subtype supermotifs were cloned into a plasmid expression vector; this expression was measured in eight human HLA class I molecule specific cell lines. Three assays for in vitro antigen presentation analysis were developed to examine the cross-bi...

journal_title：Immunological investigations

authors： Tang Y,Lin Y,Mao Y,Dong M,Wang H

更新日期：2003-02-01 00:00:00

abstract：:Results of recent studies indicated that a monoclonal ART18 antibody recognizes the receptor sites or closely related structures for IL-2 on activated rat T-cells. The major histocompatibility complex (MHC) class II (Ia) antigens (RT1B and RT1D in rat), detected with OX6 antibody, and OX17 antibody, may be present on ...

journal_title：Immunological investigations

authors： Chan CC,Caspi R,Mochizuki M,Diamantstein T,Gery I,Nussenblatt RB

更新日期：1987-06-01 00:00:00

abstract：:The rat small intestinal epithelial cell (enterocyte) has an average life span of 48h. Undifferentiated stem cells in the lower crypt region undergo division and differentiation into enterocytes as the cell moves on a basement membrane up the villus to reach the tip and be extruded into the lumen. The mechanism of thi...

journal_title：Immunological investigations

authors： Weiser MM,Ryzowicz S,Soroka CJ,Albini B

更新日期：1989-01-01 00:00:00

abstract：:The induction of immune tolerance is the most common consequence of protein feeding, i.e., "oral tolerance". In this study we investigated the genetic basis of oral tolerance using various kinds of recombinant and congenic mice, and the cells involved in the development of this phenomenon in mice. The footpad swelling...

journal_title：Immunological investigations

authors： Ishii N,Moriguchi N,Sugita Y,Nakajima H,Tanaka S,Aoki I

更新日期：1993-08-01 00:00:00

abstract：:Genome-wide association studies have led to the discovery of several susceptibility genes related to autoimmune thyroid diseases (AITDs). However, controversial results have been reported regarding the role of single-nucleotide polymorphism (SNP) of CD40 in the disease susceptibility. The objective of this study was t...

journal_title：Immunological investigations

authors： Wang D,Chen J,Zhang H,Zhang F,Yang L,Mou Y

更新日期：2017-08-01 00:00:00