Abstract:
:Anti-tumor necrosis factor-alpha (TNF-α) immunotherapy is currently used in the treatment of various inflammatory diseases such as rheumatoid arthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis and Crohn's disease. Infliximab is a chimeric monoclonal antibody that binds to transmembrane-bound and soluble TNF-α. Previously, a discoid lupus erythematosus-like eruption linked to its use was rarely reported in patients with rheumatoid arthritis. We present a case of rheumatoid arthritis which developed such an eruption after treatment with infliximab. The lesions resolved after the discontinuation of infliximab. In the present case, the clinical, serological and immunohistochemical features of our patient are discussed with the literature.
journal_name
Lupusjournal_title
Lupusauthors
Cemil BC,Atas H,Canpolat F,Akca Y,Sasmaz Rdoi
10.1177/0961203313479423subject
Has Abstractpub_date
2013-04-01 00:00:00pages
515-8issue
5eissn
0961-2033issn
1477-0962pii
22/5/515journal_volume
22pub_type
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