Primigravida is associated with flare in women with systemic lupus erythematosus.

abstract：OBJECTIVES:To determine the rates of induced abortions in women with systemic lupus erythematosus (SLE) compared to women from the general population and assess disease-related predictors of induced abortion in women with SLE. METHODS:We identified women with SLE (15-45 years) and determined the number of induced abor...

journal_title：Lupus

authors： Venne K,Scott S,Bernatsky S,Vinet E

更新日期：2020-12-15 00:00:00

abstract：:Background Patients with systemic lupus erythematosus (SLE) may form clusters with clinical manifestations and autoantibodies. Objective The objective of this report is to study whether SLE patients with positive rheumatoid factor (RF) have a special clinical and/or serological profile. Methods A retrospective study o...

journal_title：Lupus

authors： Fedrigo A,Dos Santos TAFG,Nisihara R,Skare T

更新日期：2018-07-01 00:00:00

abstract：:The antiphospholipid or Hughes syndrome is the association between antiphospholipid antibodies (aPL), venous and arterial thromboses and pregnancy morbidity. Antiphospholipid syndrome (APS) commonly coexists with autoimmune diseases usually systemic lupus erythematosus (SLE), when it is known as secondary APS. When pr...

journal_title：Lupus

authors： Karim MY,Alba P,Tungekar MF,Abbs IC,Khamashta MA,Hughes GR,Hunt BJ

更新日期：2002-01-01 00:00:00

abstract：:Vitamin D deficiency has been described in systemic lupus erythematosus (SLE). BsmI VDR (vitamin D receptor) gene polymorphism was associated with SLE in Asian patients. Studies in Brazilian populations have not been realized. A case-control study with 195 SLE patients and 201 healthy controls was conducted to investi...

journal_title：Lupus

authors： Monticielo OA,Brenol JC,Chies JA,Longo MG,Rucatti GG,Scalco R,Xavier RM

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Complement activation is central to the pathogenesis of lupus nephritis (LN). Low serum complement C3 and C4, are traditionally used as markers of lupus disease activity in general and LN in particular. In this study we prospectively measured plasma and urine C3d and C4d, degradation products of C3 and C4 ...

journal_title：Lupus

authors： Ganguly S,Majumder S,Kumar S,Gupta R,Muhammed H,Shobha V,Aggarwal A,Misra R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:We aimed to determine 1) ultrasound (US) abnormalities in patients with systemic lupus erythematosus (SLE) with and without hand arthralgia at the day of examination compared with clinical evaluation and healthy controls, and 2) inter-observer reliability of the US abnormalities. METHODS:Thirty-three female...

journal_title：Lupus

authors： Dreyer L,Jacobsen S,Juul L,Terslev L

更新日期：2015-06-01 00:00:00

abstract：:The metabolism of radioiodinated mouse IgG was studied in mice with lupus-like syndrome before and after the onset of the disease. Before the onset of the disease, the pharmacokinetic parameters of IgG in MLR-1pr and Pristane-primed Balb/c mice were within the normal range of values. After the onset of the disease a c...

journal_title：Lupus

authors： Zhou J,Pop LM,Ghetie V

更新日期：2005-01-01 00:00:00

abstract：:Our aims were to assess the frequency of false-positive IgM antibodies for cytomegalovirus in pregnant women with autoimmune diseases and in healthy women (controls) and to determine their relationship with pregnancy outcome. Data from 133 pregnancies in 118 patients with autoimmune diseases and from 222 pregnancies i...

journal_title：Lupus

authors： De Carolis S,Santucci S,Botta A,Garofalo S,Martino C,Perrelli A,Salvi S,Degennaro V,de Belvis A,Ferrazzani S,Scambia G

更新日期：2010-06-01 00:00:00

abstract：:The contribution of the p53 Arg72Pro polymorphism in the development of systemic lupus erythematosus (SLE) remains controversial. We investigated the frequency of the p53 Arg72Pro genotype in patients with SLE (n = 155) and in controls (n = 150) in Poland. We found a weak contribution of the Arg/Arg genotype to the mo...

journal_title：Lupus

authors： Piotrowski P,Lianeri M,Mostowska M,Wudarski M,Chwalinska-Sadowska H,Jagodzinski PP

更新日期：2008-02-01 00:00:00

abstract：:Consanguineous marriage is quite prevalent in the Sultanate of Oman, with up to 45% of marriages being consanguineous. The aim of this study was to determine demographic, clinical and serological characteristics between familial and non-familial cases of juvenile systemic lupus erythematosus (SLE) in a highly consangu...

journal_title：Lupus

authors： Abdwani R,Hira M,Al-Nabhani D,Al-Zakwani I

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:In a previous study performed 9 ± 3.6 years ago, 74 asymptomatic patients with systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS) underwent lung function testing. A significantly low diffusion capacity (DLCO) ranging from 45% to 70% was recorded in 28 of the 74 (37.8%) patients who wer...

journal_title：Lupus

authors： Elalouf O,Fireman E,Levartovsky D,Kaufman I,Rogovski O,Elkayam O,Caspi D,Paran D

更新日期：2015-08-01 00:00:00

abstract：:Several studies have investigated the potential of various autoantibody tests in the diagnosis of systemic lupus erythematosus (SLE). Many lupus patients initially present with glomerulonephritis. In that clinical situation the main differential diagnosis are other forms of glomerulonephritis. In this study the diagno...

journal_title：Lupus

authors： Heidenreich U,Mayer G,Herold M,Klotz W,Stempfl Al-Jazrawi K,Lhotta K

更新日期：2009-12-01 00:00:00

abstract：:Objective Genetic variants in FH (complement factor H) were reported to associate with susceptibility to systemic lupus erythematosus (SLE). This study proposed that the genetic defects of FH in the susceptibility and in the development of lupus nephritis might be different. Methods This study enrolled 334 lupus nephr...

journal_title：Lupus

authors： Tan M,Hao JB,Chu H,Wang FM,Song D,Zhu L,Yu F,Li YZ,Song Y,Zhao MH

更新日期：2017-10-01 00:00:00

abstract：:A 24 year old female with hereditary spastic paraplegia presented with intermittent headache for one year. She also had lower abdominal pain and vomiting for two months. She was pale, had icterus and mild splenomegaly. On diagnostic evaluation she was found to have hemolytic anemia, thrombocytopenia and bilateral adre...

journal_title：Lupus

authors： Abdulla MC,Alungal J,Hashim S,Ali MM,Musambil M

更新日期：2015-09-01 00:00:00

abstract：:Nephropathy of antiphospholipid antibody syndrome (NAPS) is an increasingly well-recognized aspect of antiphospholipid syndrome. The most characteristic histopathology is that of thrombotic microangiopathy, and thrombosis occurring in the renal vasculature is thought to be the initiating event. Other less common patho...

journal_title：Lupus

authors： Lin YQ,Lakshminarayanan S,Yamase H,Palmisano J,Parke A

更新日期：2009-05-01 00:00:00

abstract：:High levels of serum and/or plasma circulating DNA (cDNA) have been described in patients with systemic autoimmune diseases (SADs). However, the role of this molecule has not been clarified. Our aim was to evaluate plasma cDNA levels in 48 systemic lupus erythematosus (SLE) and 44 primary Sjögren's syndrome (SS) patie...

journal_title：Lupus

authors： Bartoloni E,Ludovini V,Alunno A,Pistola L,Bistoni O,Crinò L,Gerli R

更新日期：2011-08-01 00:00:00

abstract：:The presence of antibodies against the complex of prothrombin and phosphatidylserine (aPS/PT) more significantly correlates with manifestations of antiphospholipid syndrome (APS) and with the presence of lupus anticoagulants (LA) than antibodies against prothrombin bound to oxygenated polystyrene (aPT-A). To investiga...

journal_title：Lupus

authors： Horita T,Ichikawa K,Kataoka H,Yasuda S,Atsumi T,Koike T

更新日期：2007-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with multiple organ involvement. B-lymphocyte activity plays a pivotal role in the development and course of the disease. A newly developed agent called belimumab has recently been approved to treat active, autoantibody positive SLE as an add-on to st...

journal_title：Lupus

authors： Parodis I,Axelsson M,Gunnarsson I

更新日期：2013-04-01 00:00:00

abstract：:Skin involvement in systemic lupus erythematosus (SLE) occurs in varied forms. Lupus erythematosus tumidus (LET) is not known to occur with SLE. In our patient presented below, LET occurred in a patient with SLE. Some of the lesions progressed to scarring discoid lesions, while others responded very well to hydoxychlo...

journal_title：Lupus

authors： Jolly M,Laumann AE,Shea CR,Utset TO

更新日期：2004-01-01 00:00:00

abstract：:Tumour necrosis factor (TNFalpha) is a cytokine with a wide range of diverse and at times paradoxical effects. These include immunoregulatory, lymphoid organogenesis and pro-inflammatory effects. In recent years, TNFalpha has become a focus of interest more for its inflammatory effects in a number of chronic autoimmun...

journal_title：Lupus

authors： Mageed RA,Isenberg DA

更新日期：2002-01-01 00:00:00

abstract：:This report considers the rare situation in which primary antiphospholipid syndrome (PAPS) is linked with thrombotic thrombocytopenic purpura (TTP). It describes the case of a young lady with PAPS, characterized by recurring cerebro-vascular abnormalities and marked livedo reticularis, combined with circulating antica...

journal_title：Lupus

authors： de Carvalho JF,Freitas CA,Lima IV,Leite CC,Lage LV

更新日期：2009-08-01 00:00:00

abstract：:Atherosclerosis is recognized as the pathological basis of cardiovascular disease (CVD) and recent advances in basic science have shown that it should be considered as a chronic inflammatory process. Both elements of the innate and the adaptive immunity appear to be actively involved in atherogenesis. In fact, the pot...

journal_title：Lupus

authors： Rattazzi M,Faggin E,Bertipaglia B,Pauletto P

更新日期：2005-01-01 00:00:00

abstract：:Objective The objective of this report is to evaluate the prevalence and clinico-serological correlations of anti-α-enolase antibody (Ab) in patients with systemic lupus erythematosus (SLE). Methods Thirty-two untreated patients with SLE and 20 age- and sex-matched healthy controls were evaluated by rheumatologic exam...

journal_title：Lupus

authors： Li M,Li J,Wang J,Li Y,Yang P

更新日期：2018-01-01 00:00:00

abstract：:Objectives The carotid intima-media thickness (CIMT) and carotid arterial stiffness index (CASI) act as the surrogate markers of atherosclerosis. We aim to assess CIMT and CASI in pediatric systemic lupus erythematosus (SLE). Methods Patients ≤ 20 years old fulfilling diagnostic criteria for SLE were enrolled. Patient...

journal_title：Lupus

authors： Su-Angka N,Khositseth A,Vilaiyuk S,Tangnararatchakit K,Prangwatanagul W

更新日期：2017-08-01 00:00:00

abstract：:The aim of this study was to use transthoracic Doppler echocardiographic (TTE) imaging methods to identify cardiac dysfunction, an indicator of subclinical atherosclerosis in asymptomatic systemic lupus erythematosus (SLE) patients in terms of cardiac effects. This study involved 80 patients: a study group (n = 50) an...

journal_title：Lupus

authors： Barutcu A,Aksu F,Ozcelik F,Barutcu CA,Umit GE,Pamuk ON,Altun A

更新日期：2015-09-01 00:00:00

abstract：:Although osteoporosis has traditionally been considered a disease of women, men also incur substantial bone loss with aging, and elderly men have age-specific hip fracture incidence rates and vertebral fracture prevalence rates that are at least half those in women. Early postmenopausal bone loss (which results in the...

journal_title：Lupus

authors： Khosla S,Melton LJ 3rd,Riggs BL

更新日期：1999-01-01 00:00:00

abstract：:A 7-year-old boy presented with adrenal insufficiency. He subsequently developed venous thrombosis in the limbs and was diagnosed with primary antiphospholipid syndrome (PAPS) based on clinical and laboratory parameters. Both adrenals were normal on imaging. He required thrombolysis and anticoagulation. The progressiv...

journal_title：Lupus

authors： Bhakhri BK,Katewa S,Sharma R,Mahajan S

更新日期：2011-10-01 00:00:00

abstract：:Cardio-pulmonary manifestations of systemic lupus erythematosus (SLE) are well recognized in adults. We report the occurrence of clinically significant cardio-pulmonary disease in a cohort of predominantly Caucasian children with SLE. All children with SLE attending the Royal Liverpool Children's NHS Trust between 199...

journal_title：Lupus

authors： Beresford MW,Cleary AG,Sills JA,Couriel J,Davidson JE

更新日期：2005-01-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) has a therapeutic potential in many autoimmune diseases. Based on its immune modulating and complement inhibiting effects, IVIG has been tested in systemic lupus erythematosus (SLE), but due to osmotic tubular injury caused by immunoglobulin-stabilizing sugar components, lupus nephrit...

journal_title：Lupus

authors： Racz Z,Nagy E,Rosivall L,Szebeni J,Hamar P

更新日期：2010-04-01 00:00:00

abstract：:Objective We aimed to evaluate the relationship between telomere length and systemic lupus erythematosus (SLE). Methods PUBMED and EMBASE databases were searched; meta-analyses were performed comparing telomere length in SLE patients and healthy controls, and on SLE patients in subgroups based on ethnicity, sample typ...

journal_title：Lupus

authors： Lee YH,Jung JH,Seo YH,Kim JH,Choi SJ,Ji JD,Song GG

更新日期：2017-03-01 00:00:00