Altered pineal serotonin binding in some suicides.


:Serotonergic abnormalities have been regularly reported in the brains of suicide victims. Because of evidence that pineal function is altered in depressed subjects and that serotonin-releasing axons may innervate the pineal, we assayed tritiated serotonin binding in a series of control and suicide pineals. High affinity binding was present, and there were apparent differences between some suicides and controls.


Psychiatry Res


Psychiatry research


Sparks DL,Little KY




Has Abstract


1990-04-01 00:00:00














  • The short-term impact of generic versus individualized environmental supports on functional outcomes and target behaviors in schizophrenia.

    abstract::We examined the short-term efficacy of two treatments using environmental supports (e.g. signs, alarms, pill containers, and checklists) to improve target behaviors in individuals with schizophrenia. 120 participants were randomized into one of the following three treatment groups: 1) Cognitive Adaptation Training (CA...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验


    authors: Velligan DI,Diamond P,Mueller J,Li X,Maples N,Wang M,Miller AL

    更新日期:2009-07-30 00:00:00

  • Language disturbance and functioning in first episode psychosis.

    abstract::Language disturbance has a central role in the presentation of psychotic disorders however its relationship with functioning requires further clarification, particularly in first episode psychosis (FEP). Both language disturbance and functioning can be evaluated with clinician-rated and performance-based measures. We ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Roche E,Segurado R,Renwick L,McClenaghan A,Sexton S,Frawley T,Chan CK,Bonar M,Clarke M

    更新日期:2016-01-30 00:00:00

  • Amygdala and hippocampal volume reductions as candidate endophenotypes for borderline personality disorder: a meta-analysis of magnetic resonance imaging studies.

    abstract::Borderline personality disorder (BPD) is a genetically influenced psychiatric illness with disruptions in neural systems supporting cognition and emotion regulation. Volumetric decreases of the hippocampus and amygdala may characterize BPD and serve as putative endophenotypes for the illness. The purpose of the presen...

    journal_title:Psychiatry research

    pub_type: 杂志文章,meta分析,评审


    authors: Ruocco AC,Amirthavasagam S,Zakzanis KK

    更新日期:2012-03-31 00:00:00

  • A breakdown of event schemas in patients with schizophrenia: an examination of their script for dining at restaurants

    abstract::Event schemas, the conceptualization of past experience, in schizophrenic patients were examined based upon script theory. Forty schizophrenic patients and 40 age- and education-matched normal control subjects participated in this study. This experiment consisted of three tasks. In the recall task, subjects recalled a...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Chan AS,Chiu H,Lam L,Pang A,Chow LY

    更新日期:1999-10-11 00:00:00

  • White matter abnormalities associated with disruptive behavior disorder in adolescents with and without attention-deficit/hyperactivity disorder.

    abstract::Disruptive behavior disorders (DBD) are among the most commonly diagnosed mental disorders in children and adolescents. Some important characteristics of DBD vary based on the presence or absence of comorbid attention-deficit/hyperactivity disorder (ADHD), which may affect the understanding of and treatment decision-m...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Wang Y,Horst KK,Kronenberger WG,Hummer TA,Mosier KM,Kalnin AJ,Dunn DW,Mathews VP

    更新日期:2012-06-30 00:00:00

  • Relationship of object loss during development to hypothalamic-pituitary-adrenal axis function during major affective illness later in life.

    abstract::Although many studies have attempted to determine whether early object loss influences the risk of developing major affective illness in adulthood, there are few empirical data relating early loss to subsequent hypothalamic-pituitary-adrenal (HPA) axis dysfunction in adulthood. Forty-five psychiatric inpatients admitt...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Petitto JM,Quade D,Evans DL

    更新日期:1992-12-01 00:00:00

  • Intact perception of coherent motion, dynamic rigid form, and biological motion in chronic schizophrenia.

    abstract:BACKGROUND:Prior studies have documented biological motion perception deficits in schizophrenia, but it remains unclear whether the impairments arise from poor social cognition, perceptual organization, basic motion processing, or sustained attention/motivation. To address the issue, we had 24 chronic schizophrenia pat...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Keane BP,Peng Y,Demmin D,Silverstein SM,Lu H

    更新日期:2018-10-01 00:00:00

  • Depressed mood in individuals with schizophrenia: A comparison of retrospective and real-time measures.

    abstract::Depressed mood is prevalent among individuals with schizophrenia, leading to difficulties in functioning. Typically, depressed mood is evaluated using retrospective assessments during which individuals are asked to recall their mood during the past week or month. However, as individuals with schizophrenia may display ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Blum LH,Vakhrusheva J,Saperstein A,Khan S,Chang RW,Hansen MC,Zemon V,Kimhy D

    更新日期:2015-06-30 00:00:00

  • Mediation effect of beliefs about pleasure and emotional experience between social anhedonia and prediction of pleasant events.

    abstract::Few studies have examined whether there is a relationship between social anhedonia and prediction of future events and the role of beliefs about pleasure and emotional experience. In this study, 513 college students were recruited to complete a set of self-reported questionnaires, including the Revised Social Anhedoni...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Hu HX,Chu MY,Yang Y,Wang LL,Zhang RT,Lui SSY,Cheung EFC,Chan RCK

    更新日期:2018-06-01 00:00:00

  • Prevalence and risk factors of agitation in newly hospitalized schizophrenia patients in China: An observational survey.

    abstract::This multi-center observational study investigated the prevalence of agitation in newly hospitalized schizophrenia patients in China and its potential risk factors. It was performed in 2014 and covered 14 hospitals. Newly hospitalized patients with schizophrenia or suspected schizophrenia who met the diagnostic criter...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Mi W,Zhang S,Liu Q,Yang F,Wang Y,Li T,Mei Q,He H,Chen Z,Su Z,Liu T,Xie S,Tan Q,Zhang J,Zhang C,Sang H,Chen W,Shi L,Li L,Shi Y,Guo L,Zhang H,Lu L

    更新日期:2017-07-01 00:00:00

  • Nature of anxiety comorbid with attention deficit hyperactivity disorder in children from a pediatric primary care setting.

    abstract::The clinical characteristics of children with comorbid anxiety and attention deficit hyperactivity disorder (ADHD were examined. A sample of children from a pediatric primary care practice was assessed for anxiety disorders and ADHD. We defined four groups of children: (1) anxiety disorders only with no ADHD (n=54); (...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Bowen R,Chavira DA,Bailey K,Stein MT,Stein MB

    更新日期:2008-01-15 00:00:00

  • Standardization of Brief Inventory of Social Support Exchange Network (BISSEN) in Japan.

    abstract::This study describes the Brief Inventory of Social Support Exchange Network (BISSEN) as a standardized brief inventory measuring various aspects of social support. We confirmed the reliability and validity for function and direction of support and standardized the BISSEN. For Sample 1, a stratified random sampling met...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Aiba M,Tachikawa H,Fukuoka Y,Lebowitz A,Shiratori Y,Doi N,Matsui Y

    更新日期:2017-07-01 00:00:00

  • Event-related potentials elicited by distractors in an auditory oddball paradigm in schizophrenia.

    abstract::Patients with schizophrenia are affected more adversely than healthy controls by distracting conditions, due to their inability to adequately apportion attentional resources to targets or distractors. We attempted to re-evaluate the effects of distractors in 25 patients with chronic schizophrenia and in 12 controls. T...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Kogoj A,Pirtosek Z,Tomori M,Vodusek DB

    更新日期:2005-11-15 00:00:00

  • Diffusion tensor imaging reveals white matter abnormalities in Attention-Deficit/Hyperactivity Disorder.

    abstract::The specific brain structures or neural mechanisms underlying dysfunction in individuals with Attention-Deficit/Hyperactivity Disorder (ADHD) are not well established, particularly in regard to white matter (WM). Diffusion tensor imaging (DTI) was used to investigate WM in 12 adolescent males diagnosed with ADHD only ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Tamm L,Barnea-Goraly N,Reiss AL

    更新日期:2012-05-31 00:00:00

  • Altered relationships between age and functional brain activation in adolescents at clinical high risk for psychosis.

    abstract::Schizophrenia is considered a neurodevelopmental disorder, but whether the adolescent period, proximal to onset, is associated with aberrant development in individuals at clinical high risk (CHR) for psychosis is incompletely understood. While abnormal gray and white matter development has been observed, alterations i...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Karlsgodt KH,van Erp TG,Bearden CE,Cannon TD

    更新日期:2014-01-30 00:00:00

  • Effects of season on electro-oculographic ratio in winter seasonal affective disorder.

    abstract::Low electro-oculographic (EOG) ratios have been reported in patients with seasonal affective disorder (SAD) during the winter. This study evaluated the effects of the changing seasons on EOG ratios in SAD patients. Sixteen outpatients with SAD and 16 age-, sex-, and medication-matched normal volunteers had EOG testing...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Ozaki N,Rosenthal NE,Myers F,Schwartz PJ,Oren DA

    更新日期:1995-11-29 00:00:00

  • The temporal relationship between premonitory urges and covert compulsions in patients with obsessive-compulsive disorder.

    abstract::Recent studies in patients with obsessive-compulsive disorder (OCD) have shown that many compulsions are associated with urges rather than obsessions. Premonitory urges are uncomfortable sensory feelings or a rising inner tension, often likened to the urge to scratch, yawn or blink. We studied premonitory urges preced...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Brandt VC,Hermanns J,Beck C,Bäumer T,Zurowski B,Münchau A

    更新日期:2018-04-01 00:00:00

  • Psychiatrists׳ fear of death is associated with negative emotions toward borderline personality disorder patients.

    abstract::This study examines the relationship between psychiatrists׳ fear of death and negative emotions toward patients with borderline personality disorder (BPD). A survey (N=120) demonstrated that fear of death is associated with stronger negative attitudes toward BPD patients, after controlling for attitudes toward suicide...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Bodner E,Shrira A,Hermesh H,Ben-Ezra M,Iancu I

    更新日期:2015-08-30 00:00:00

  • Cocaine-induced psychotic symptoms in French cocaine addicts.

    abstract::Cocaine use is known to induce transient psychotic symptoms. We evaluated retrospectively the lifetime prevalence of cocaine-induced psychotic symptoms in 105 cocaine addicts with the French version of the Scale for Assessment of Positive Symptoms-Cocaine Induced Psychosis (SAPS-CIP) in a clinical setting. Most patien...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Vorspan F,Brousse G,Bloch V,Bellais L,Romo L,Guillem E,Coeuru P,Lépine JP

    更新日期:2012-12-30 00:00:00

  • Brain activation patterns during a selective attention test-a functional MRI study in healthy volunteers and patients with schizophrenia.

    abstract::Functional magnetic resonance imaging was used to compare cortical activation patterns in healthy volunteers with those in patients with schizophrenia during a modified verbal Stroop task. Healthy subjects (n=13) and patients with schizophrenia (n=13) on stable antipsychotic treatment, matched on demographic variables...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Weiss EM,Golaszewski S,Mottaghy FM,Hofer A,Hausmann A,Kemmler G,Kremser C,Brinkhoff C,Felber SR,Fleischhacker WW

    更新日期:2003-05-01 00:00:00

  • Plasma tryptophan levels and tryptophan/neutral amino acid ratios in obsessive-compulsive patients with and without depression.

    abstract::We have studied fasting plasma tryptophan (TRP) levels and tryptophan/large neutral amino acid (TRP/LNAA) ratios in 12 patients with obsessive-compulsive disorder (OCD) and 12 patients with OCD and a coexisting current diagnosis of major depressive disorder (OCD-MDD). Assessments were made at baseline and after 6 week...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Bellodi L,Erzegovesi S,Bianchi L,Lucini V,Conca R,Lucca A

    更新日期:1997-03-03 00:00:00

  • Interleukin-1 receptor antagonist genotype and brain morphometry in first-episode non-affective psychosis.

    abstract::Studies of schizophrenia that combine imaging and genetic approaches attempt to map structural brain anomalies associated with genetic risk variants. The aim of the present study was to investigate whether variations in the interleukin-1 receptor antagonist (IL-1RN) were associated with structural brain characteristic...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Roiz-Santiáñez R,Crespo-Facorro B,Pérez-Iglesias R,Pelayo-Terán JM,Carrasco-Marín E,Mata I,Sánchez E,Leyva-Cobián F,Vázquez-Barquero JL

    更新日期:2008-02-28 00:00:00

  • Association between family history of mental disorders and outcome in psychotic disorders.

    abstract::We investigated the association of family history of mental disorders, especially psychosis, with occupational and clinical outcome in psychotic disorders in a longitudinal population-based cohort. The Northern Finland Birth Cohort 1986 (n = 9432) was used to gather the data. In total 189 individuals with psychosis we...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Käkelä J,Nordström T,Haapea M,Jääskeläinen E,Miettunen J

    更新日期:2018-12-01 00:00:00

  • Factors affecting reliability and confidence of DSM-III-R psychosis-related diagnosis.

    abstract::The relationships between interrater diagnostic reliability, confidence in diagnosis, DSM-III-R criteria ambiguity and case report data quality were examined in 20 case vignettes describing psychosis-related symptomatology. Each of seven diagnosticians made DSM-III-R diagnoses and gave confidence ratings for those dia...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Gutkind D,Ventura J,Barr C,Shaner A,Green M,Mintz J

    更新日期:2001-04-15 00:00:00

  • Executive control in schizophrenia in task involving semantic inhibition and working memory.

    abstract::Executive dysfunctions have been consistently demonstrated in patients with schizophrenia. This study aimed to investigate deficits in specific executive functioning components, namely working memory and inhibition, in schizophrenia. In study 1, a set of neurocognitive function tests was administered to 41 patients wi...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Chan RC,Huang J,Guo L,Cao X,Hong X,Gao Z

    更新日期:2010-10-30 00:00:00

  • Emotional intelligence as a mediator between rumination and suicidal ideation among depressed inpatients: The moderating role of suicidal history.

    abstract::Suicide is a substantial public health problem, and it remains a serious cause of death in the world. Therefore, this study was designed to examine the relationships between brooding, reflection, emotional intelligence (assessed by performance-based test), and suicidal ideation; the mediation role of emotional intelli...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Abdollahi A,Talib MA

    更新日期:2015-08-30 00:00:00

  • The (b)link between amotivation and psychosis: Insights through phasic eye blink rate.

    abstract::Motivation deficits within Schizophrenia Spectrum Disorders (SSDs) are associated with abnormal striatal dopamine responses during reward processing. Eye blink rate (EBR) has been used as a proxy for striatal dopamine; however, it is unclear whether EBR is sensitive to individual differences in amotivation. Amotivatio...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: McGovern JE,Masucci MD,Le TP,Cohen AS

    更新日期:2020-12-01 00:00:00

  • Assessment of the frequency criterion for the diagnosis of non-suicidal self-injury disorder in female adolescents with conduct disorder.

    abstract::Recent studies suggest a higher threshold number of self-injuries during the past year than the one proposed in the DSM-5 criteria for non-suicidal self-injury disorder (NSSID). Therefore, we aimed to test a validity of the frequency criterion in girls with conduct disorder (CD) based on psychopathology and the level ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Szewczuk-Bogusławska M,Kaczmarek-Fojtar M,Moustafa AA,Mahlberg J,Frydecka D,Oleszkowicz A,Bąk O,Misiak B

    更新日期:2018-09-01 00:00:00

  • Plasma dopamine beta-hydroxylase activity in psychotic and non-psychotic post-traumatic stress disorder.

    abstract::Recognition and treatment of comorbid chronic psychotic symptoms in post-traumatic stress disorder (PTSD) has become of increasing clinical interest. Altered dopamine beta-hydroxylase (DBH) activity has been reported in mood disorders. Plasma DBH is reduced in major depression with psychosis and elevated in bipolar di...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Hamner MB,Gold PB

    更新日期:1998-02-27 00:00:00

  • Emotional exhaustion and its relationship with suicide risk in emergency responders.

    abstract::The purpose of the current study was to evaluate the relationship between emotional exhaustion and suicide risk in emergency responders. Participants included 643 actively employed emergency responders who responded to an online research based survey. Participants were administered the Maslach Burnout Inventory (MBI; ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Edwards DL,Wilkerson ND

    更新日期:2020-11-01 00:00:00