Microalgal compounds modulate carcinogenesis in the gastrointestinal tract.

abstract：:In the future, biomass will continue to emerge as a viable source of chemicals. The development of new industries that utilize bio-renewables provides opportunities for innovation. For example, bio- and chemo-catalysts can be combined in 'one pot' to prepare chemicals of commercial value. This has been demonstrated us...

journal_title：Trends in biotechnology

authors： Marr AC,Liu S

更新日期：2011-05-01 00:00:00

abstract：:Anywhere water is in the liquid state, bacteria will exist as biofilms, which are complex communities of cells that are cemented together. Although frequently associated with disease and biofouling, biofilms are also important for engineering applications, such as bioremediation, biocatalysis and microbial fuel cells....

journal_title：Trends in biotechnology

authors： Wood TK,Hong SH,Ma Q

更新日期：2011-02-01 00:00:00

abstract：:Bacteriophages encode many distinct proteins for the successful infection of a bacterial host. Each protein plays a specific role in the phage replication cycle, from host recognition, through takeover of the host machinery, and up to cell lysis for progeny release. As the roles of these proteins are being revealed, m...

journal_title：Trends in biotechnology

authors： Santos SB,Costa AR,Carvalho C,Nóbrega FL,Azeredo J

更新日期：2018-09-01 00:00:00

abstract：:We have isolated several microorganisms that are adapted to living in the extremes of the deep-sea environment. They include barophilic bacteria, which are able to grow at high hydrostatic pressure, but that are unable to grow at atmospheric pressure, and organic-solvent-tolerant bacteria, which are able to grow in th...

journal_title：Trends in biotechnology

authors： Kato C,Inoue A,Horikoshi K

更新日期：1996-01-01 00:00:00

abstract：:The analysis of biomolecules using microarrays and other biosensors has a significant role in molecular biotechnology, and will become even more important in the future as a versatile tool for research and diagnostics. For many applications, the synthetic DNA mimic peptide nucleic acid (PNA) could be advantageous as a...

journal_title：Trends in biotechnology

authors： Brandt O,Hoheisel JD

更新日期：2004-12-01 00:00:00

abstract：:Creating a magic bullet that can selectively kill cancer cells while sparing nearby healthy cells remains one of the most ambitious objectives in pharmacology. Nanomedicine, which relies on the use of nanotechnologies to fight disease, was envisaged to fulfill this coveted goal. Despite substantial progress, the struc...

journal_title：Trends in biotechnology

authors： Lussier F,Staufer O,Platzman I,Spatz JP

更新日期：2020-09-07 00:00:00

abstract：:Cancer is one of the most prevalent diseases worldwide, which explains why biological therapies for cancer are forecast to make up 35% of total recombinant pharmaceuticals by 2010. Because of the high demand for cancer drugs, the need to lower production costs and the constraints of present production technologies for...

journal_title：Trends in biotechnology

authors： Pujol M,Gavilondo J,Ayala M,Rodríguez M,González EM,Pérez L

更新日期：2007-10-01 00:00:00

abstract：:Predicting the future use of biocatalysts for the transformation of organic compounds--both natural substrates and other compounds--needs to take many factors into account. To date, relatively few biotransformations have been developed to the industrial scale, primarily because there has been little economic incentive...

journal_title：Trends in biotechnology

authors： Faber K,Franssen MC

更新日期：1993-11-01 00:00:00

abstract：:Microbial consortia have been used in biotechnology processes, including fermentation, waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly engineering microbial consortia for diverse applications, including the bioproduction of medicines, biofuels, and biomaterials from inexpe...

journal_title：Trends in biotechnology

authors： McCarty NS,Ledesma-Amaro R

更新日期：2019-02-01 00:00:00

abstract：:Diabetes affects 150 million people worldwide and results from abnormal function of pancreatic islets. The scarcity of human tissue donors has focused interest in developing renewable sources of insulin-producing cells appropriate for engraftment. Advances in stem cell technology and transdifferentiation techniques ha...

journal_title：Trends in biotechnology

authors： Orive Arroyo G,Hernánedez RM,Gascón AR,Igartua M,Pedraz JL

更新日期：2003-07-01 00:00:00

abstract：:Techniques to enable direct communication between the brain and computers/machines, such as the brain-computer interface (BCI) or the brain-machine interface (BMI), are gaining momentum in the neuroscientific realm, with potential applications ranging from medicine to general consumer electronics. Noninvasive BCI tech...

journal_title：Trends in biotechnology

authors： Min BK,Marzelli MJ,Yoo SS

更新日期：2010-11-01 00:00:00

abstract：:Lyases catalyse the cleavage of C-C, C-N, C-O and other bonds by elimination to produce double bonds or, conversely, catalyse the addition of groups to double bonds. These enzymes do not require cofactor recycling, show an absolute stereospecificity and can give a theoretical yield of 100%, compared with only 50% for ...

journal_title：Trends in biotechnology

authors： van der Werf MJ,van den Tweel WJ,Kamphuis J,Hartmans S,de Bont JA

更新日期：1994-03-01 00:00:00

abstract：:Technology is a social practice that embodies the capacity of societies to transform themselves by creating and manipulating not only physical objects, but also symbols and cultural forms. It is an illusion that scientific and socioeconomic drivers are the sole elements determining the destiny of a technology. Althoug...

journal_title：Trends in biotechnology

authors： Mordini E

更新日期：2007-12-01 00:00:00

abstract：:Along with the development of metabolic engineering and synthetic biology tools, various microbes are being used to produce aromatic chemicals. In microbes, aromatics are mainly produced via a common important precursor, chorismate, in the shikimate pathway. Natural or non-natural aromatics have been produced by engin...

journal_title：Trends in biotechnology

authors： Noda S,Kondo A

更新日期：2017-08-01 00:00:00

abstract：:Bacterial genomics has provided a plethora of potential targets for antibacterial drug discovery, however, success in the hunt for new antibiotics will hinge on selecting targets with the highest potential. A recent paper by Liu and coworkers describes a new approach to target selection that uncovers strategies used b...

journal_title：Trends in biotechnology

authors： Brown ED

更新日期：2004-09-01 00:00:00

abstract：:The global movement of people and goods has increased the risk of biosecurity threats and their potential to incur large economic, social, and environmental costs. Conventional manual biosecurity surveillance methods are limited by their scalability in space and time. This article focuses on autonomous surveillance sy...

journal_title：Trends in biotechnology

authors： Jurdak R,Elfes A,Kusy B,Tews A,Hu W,Hernandez E,Kottege N,Sikka P

更新日期：2015-04-01 00:00:00

abstract：:Breath-based metabolomics (breathomics) is an exciting developing area of biotechnology that centers on the capture, identification, and quantification of volatile organic compound (VOC) patterns in human breath and their utilization as tools in the diagnosis of a broad spectrum of medical problems. With the age of pe...

journal_title：Trends in biotechnology

authors： Rattray NJ,Hamrang Z,Trivedi DK,Goodacre R,Fowler SJ

更新日期：2014-10-01 00:00:00

abstract：:In recent years, entrapment of cells within spheres of Ca2+ alginate has become the most widely used technique for immobilizing living cells. This versatile method includes applications ranging from immobilization of living or dead cells in bioreactors, immobilization of plant protoplasts for micropropagation and immo...

journal_title：Trends in biotechnology

authors： Smidsrød O,Skjåk-Braek G

更新日期：1990-03-01 00:00:00

abstract：:Advances in our capacity to design and use novel strategies for achieving inducible gene expression will improve our ability to define gene function. An extremely efficient system designed by nature -- that of the regulatable phytochrome system in plants -- has provided the basis for developing a novel inducible gene ...

journal_title：Trends in biotechnology

authors： Keyes WM,Mills AA

更新日期：2003-02-01 00:00:00

abstract：:The extensive use of chemical insecticides for insect pest management has resulted in insecticide resistance now being recorded in >500 species of insects and mites. Although gut-active toxins such as those derived from Bacillus thuringiensis (Bt) have been successfully used for insect pest management, a diverse range...

journal_title：Trends in biotechnology

authors： Bonning BC,Chougule NP

更新日期：2014-02-01 00:00:00

abstract：:Pressure is a thermodynamic parameter whose unique effects on biological systems are increasingly being studied in a growing number of scientific fields. As such, the effects of high pressure are currently being investigated at different levels, ranging from proteins, enzymes and viruses to microorganisms, mammalian c...

journal_title：Trends in biotechnology

authors： Aertsen A,Meersman F,Hendrickx ME,Vogel RF,Michiels CW

更新日期：2009-07-01 00:00:00

abstract：:Opinions on what synthetic biology actually is range from a natural extension of genetic engineering to a new manufacturing paradigm. It offers, for the first time in the life sciences, rational design and engineering standardisation. It could address problems across a broad spectrum of human concerns, including energ...

journal_title：Trends in biotechnology

authors： Philp JC,Ritchie RJ,Allan JE

更新日期：2013-05-01 00:00:00

abstract：:Hydrophobic charge induction chromatography using 4-mercapto-ethyl-pyridine as the ligand is an effective method for the separation of antibodies from a variety of feedstocks. Antibodies are adsorbed in physiological conditions without preliminary concentration. Desorption occurs when the pH is lowered, thus inducing ...

journal_title：Trends in biotechnology

authors： Boschetti E

更新日期：2002-08-01 00:00:00

abstract：:Luminescence has assumed an important role in analytical biochemistry and molecular biology as an extremely sensitive method for determining the concentration of specific ions and molecules. The luminescent system of the jellyfish Aequorea victoria consists of the photoprotein aequorin, which contains the molecule coe...

journal_title：Trends in biotechnology

authors： Jones K,Hibbert F,Keenan M

更新日期：1999-12-01 00:00:00

abstract：:The glycosylation profile of a recombinant glycoprotein can not only significantly affect its therapeutic profile, but is also extremely sensitive to cell-culture and purification conditions. To define glycosylation patterns and to ensure consistency of recombinant glycoproteins among different preparations requires h...

journal_title：Trends in biotechnology

authors： Parekh RB,Patel TP

更新日期：1992-08-01 00:00:00

abstract：:Acidity is a biomarker of cancer that is not subject to the blunting clonal selection effects that reduce the efficacy of other biomarker technologies, such as antibody targeting. The pH (low) insertion peptides (pHLIP®s) provide new opportunities for targeting acidic tissues. Through the physical mechanism of membran...

journal_title：Trends in biotechnology

authors： Wyatt LC,Lewis JS,Andreev OA,Reshetnyak YK,Engelman DM

更新日期：2017-07-01 00:00:00

abstract：:Stem cell differentiation is regulated by the complex interplay of multiple parameters, including adhesive intercellular interactions, cytoskeletal and extracellular matrix remodeling, and gradients of agonists and antagonists that individually and collectively vary as a function of spatial locale and temporal stages ...

journal_title：Trends in biotechnology

authors： Kinney MA,McDevitt TC

更新日期：2013-02-01 00:00:00

abstract：:Europe has led many aspects of gene research and yet it has been unable to translate these discoveries into a globally dominant industrial sector. There are valid societal, political and financial reasons for its reluctance to deploy agricultural biotechnology but this reluctance might have unintended consequences. It...

journal_title：Trends in biotechnology

authors： Enriquez J

更新日期：2001-04-01 00:00:00

abstract：:A recent publication has reported the fabrication of a new microbial culture device containing an array of unprecedented density - a million growth chambers. This micro-Petri chip should impact on various fields, including biotechnology, ecology, food microbiology and drug development, by enabling high-throughput scre...

journal_title：Trends in biotechnology

authors： Gefen O,Balaban NQ

更新日期：2008-07-01 00:00:00

abstract：:Platelet-derived products (PDPs) have gained popularity, mainly due to their high concentrations of bioactive molecules such as growth factors and cytokines, which play important roles in tissue healing and regeneration. PDPs are obtained through minimally invasive procedures and their therapeutic effect has been wide...

journal_title：Trends in biotechnology

authors： Soares CS,Babo PS,Reis RL,Carvalho PP,Gomes ME

更新日期：2020-08-28 00:00:00