Abstract:
:Pressure is a thermodynamic parameter whose unique effects on biological systems are increasingly being studied in a growing number of scientific fields. As such, the effects of high pressure are currently being investigated at different levels, ranging from proteins, enzymes and viruses to microorganisms, mammalian cells and tissues. Together with the steadily growing knowledge and understanding of high pressure effects on these increasingly complex systems, the purposeful use of high pressure has found several unique applications in bioscience over the past few years, including the disaggregation of proteins, the preparation of viral vaccines and the modulation of food functionality. In this review, recent and emerging applications of high pressure in biotechnology are presented and discussed.
journal_name
Trends Biotechnoljournal_title
Trends in biotechnologyauthors
Aertsen A,Meersman F,Hendrickx ME,Vogel RF,Michiels CWdoi
10.1016/j.tibtech.2009.04.001subject
Has Abstractpub_date
2009-07-01 00:00:00pages
434-41issue
7eissn
0167-7799issn
1879-3096pii
S0167-7799(09)00094-8journal_volume
27pub_type
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