Abstract：
:Bacteriophages encode many distinct proteins for the successful infection of a bacterial host. Each protein plays a specific role in the phage replication cycle, from host recognition, through takeover of the host machinery, and up to cell lysis for progeny release. As the roles of these proteins are being revealed, more biotechnological applications can be anticipated. Phage-encoded proteins are now being explored for the control, detection, and typing of bacteria; as vehicles for drug delivery; and for vaccine development. In this review, we discuss how engineering approaches can be used to improve the natural properties of these proteins and set forth the most innovative applications that demonstrate the unlimited biotechnological potential held by phage-encoded proteins.
journal_name
Trends Biotechnoljournal_title
Trends in biotechnologyauthors
Santos SB,Costa AR,Carvalho C,Nóbrega FL,Azeredo Jdoi
10.1016/j.tibtech.2018.04.006subject
Has Abstractpub_date
2018-09-01 00:00:00pages
966-984issue
9eissn
0167-7799issn
1879-3096pii
S0167-7799(18)30119-7journal_volume
36pub_type
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