Alginate as immobilization matrix for cells.

Abstract:

:In recent years, entrapment of cells within spheres of Ca2+ alginate has become the most widely used technique for immobilizing living cells. This versatile method includes applications ranging from immobilization of living or dead cells in bioreactors, immobilization of plant protoplasts for micropropagation and immobilization of hybridoma cells for production of monoclonal antibodies, to entrapment of animal cells for implantation of artificial organs. This review evaluates the potential of this method on the basis of the current knowledge of structural and functional relationships in alginate gels.

journal_name

Trends Biotechnol

journal_title

Trends in biotechnology

authors

Smidsrød O,Skjåk-Braek G

doi

10.1016/0167-7799(90)90139-o

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

71-8

issue

3

eissn

0167-7799

issn

1879-3096

journal_volume

8

pub_type

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