Abstract:
:A main field in biomedical optics research is diffuse optical tomography, where intensity variations of the transmitted light traversing through tissue are detected. Mathematical models and reconstruction algorithms based on finite element methods and Monte Carlo simulations describe the light transport inside the tissue and determine differences in absorption and scattering coefficients. Precise knowledge of the sample's surface shape and orientation is required to provide boundary conditions for these techniques. We propose an integrated method based on structured light three-dimensional (3-D) scanning that provides detailed surface information of the object, which is usable for volume mesh creation and allows the normalization of the intensity dispersion between surface and camera. The experimental setup is complemented by polarization difference imaging to avoid overlaying byproducts caused by inter-reflections and multiple scattering in semitransparent tissue.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Baum K,Hartmann R,Bischoff T,Oelerich JO,Finkensieper S,Heverhagen JTdoi
10.1117/1.JBO.17.12.126009subject
Has Abstractpub_date
2012-12-01 00:00:00pages
126009issue
12eissn
1083-3668issn
1560-2281pii
1473703journal_volume
17pub_type
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