Abstract:
:So far, the study of the optical clearing is almost always about healthy tissue. However, the ultimate goal is to detect diseases for clinical application. Optical clearing on diseased skins is explored. The effect is evaluated by applying a combined liquid paraffin and glycerol mixed solution on several kinds of diseased skins in vitro. Scanning experiments from optical coherence tomography show that it has different effects among fibroma, pigmented nevus, and seborrheic keratosis. Based on the results, we conclude that different skin diseases have different compositions and structures, and their optical parameters and biological characteristics should be different, which implies that the optical clearing technique may have selectivity and may not be suitable for all kinds of skin diseases.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Shan H,Liang Y,Wang J,Li Ydoi
10.1117/1.JBO.17.11.115003subject
Has Abstractpub_date
2012-11-01 00:00:00pages
115003issue
11eissn
1083-3668issn
1560-2281pii
1390423journal_volume
17pub_type
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