Caries detection and quantification around stained pits and fissures in occlusal tooth surfaces with fluorescence.

abstract：:A swept source (SS)-based circular-state (CS) polarization-sensitive optical coherence tomography (PS-OCT) constructed entirely with polarization-maintaining fiber optics components is proposed with the experimental verification. By means of the proposed calibration scheme, bulk quarter-wave plates can be replaced by ...

journal_title：Journal of biomedical optics

authors： Lin H,Kao MC,Lai CM,Huang JC,Kuo WC

更新日期：2014-02-01 00:00:00

abstract：:The optical activity of glucose molecules is important for diagnosing and monitoring blood glucose of diabetes. In order to accurately detect the diabetes at an early stage, there is an urgent need to develop innovative detection methods. By use of Mueller matrix decomposition (MMD), we have studied the optical activi...

journal_title：Journal of biomedical optics

authors： Sun P,Ma Y,Liu W,Yang Q,Jia Q

更新日期：2014-04-01 00:00:00

abstract：:Imaging large areas of tissue rapidly and with high resolution may enable rapid pathology at the bedside. The limited field of view of high-resolution microscopes requires the merging of multiple images that are taken sequentially to cover a large area. This merging or mosaicing of images requires long acquisition and...

journal_title：Journal of biomedical optics

authors： Abeytunge S,Li Y,Larson B,Toledo-Crow R,Rajadhyaksha M

更新日期：2011-05-01 00:00:00

abstract：:The measurement of changes in blood volume in tissue is important for monitoring the effects of a wide range of therapeutic interventions, from radiation therapy to skin-flap transplants. Many systems available for purchase are either expensive or difficult to use, limiting their utility in the clinical setting. A low...

journal_title：Journal of biomedical optics

authors： Glennie DL,Hayward JE,McKee DE,Farrell TJ

更新日期：2014-01-01 00:00:00

abstract：:Intrauterine photoacoustic and ultrasound imaging are probe-based imaging modalities with translational potential for use in detecting endometrial diseases. This deep-tissue imaging probe design allows for the retrofitting of commercially available endometrial sampling curettes. The imaging probe presented here has a ...

journal_title：Journal of biomedical optics

authors： Miranda C,Barkley J,Smith B

更新日期：2018-04-01 00:00:00

abstract：:In-vivo imaging of the vascular system can provide novel insight into the dynamics of vasoconstriction and vasodilation. Fourier domain optical coherence tomography (FD-OCT) is an optical, noncontact imaging technique based on interferometry of short-coherent near-infrared light with axial resolution of less than 10 m...

journal_title：Journal of biomedical optics

authors： Meissner S,Müller G,Walther J,Morawietz H,Koch E

更新日期：2009-05-01 00:00:00

abstract：:Measuring the elasticity distribution inside the human body is of great interest because elastic abnormalities can serve as indicators of several diseases. We present a method for mapping elasticity inside soft tissues by imaging surface acoustic waves (SAWs) with digital holographic interferometry. With this method, ...

journal_title：Journal of biomedical optics

authors： Li S,Mohan KD,Sanders WW,Oldenburg AL

更新日期：2011-11-01 00:00:00

abstract：:We have developed a near-infrared (NIR) fluorescence goggle system based on the complementary metal-oxide-semiconductor active pixel sensor imaging and see-through display technologies. The fluorescence goggle system is a compact wearable intraoperative fluorescence imaging and display system that can guide surgery in...

journal_title：Journal of biomedical optics

authors： Liu Y,Njuguna R,Matthews T,Akers WJ,Sudlow GP,Mondal S,Tang R,Gruev V,Achilefu S

更新日期：2013-10-01 00:00:00

abstract：:A simultaneous multispectral fluorescence imaging system incorporating multiplexed volume holographic grating (VHG) is developed to acquire multispectral images of an object in one shot. With the multiplexed VHG, the imaging system can provide the distribution and spectral characteristics of multiple fluorophores in t...

journal_title：Journal of biomedical optics

authors： Lv Y,Zhang J,Zhang D,Cai W,Chen N,Luo J

更新日期：2016-06-01 00:00:00

abstract：:Noninvasive cardiovascular imaging could lead to the early detection and timely treatment of complex atherosclerotic lesions responsible for major cardiovascular events. Recent investigations have suggested that optical coherence tomography (OCT) is an ideal diagnostic tool due to the high resolution this technology a...

journal_title：Journal of biomedical optics

authors： Ghosn MG,Carbajal EF,Befrui NA,Tellez A,Granada JF,Larin KV

更新日期：2008-01-01 00:00:00

abstract：:Utilizing a laser scanning confocal microscope system, the refractive indices of articular cartilage (AC) with mechanical or biochemical degenerations were characterized to investigate whether potential correlations exist between refractive index (RI) and cartilage degeneration. The cartilage samples collected from th...

journal_title：Journal of biomedical optics

authors： Wang K,Wu J,Day R,Kirk TB,Hu X

更新日期：2016-09-01 00:00:00

abstract：UNLABELLED:Temperature changes caused by laser irradiation can promote damage to the surrounding dental tissues. In this study, we evaluated the temperature changes of recently extracted human mandibular incisors during intracanal irradiation with an 810-nm diode laser at different settings. Fifty mandibular incisors w...

journal_title：Journal of biomedical optics

authors： da Fonseca Alvarez A,Moura-Netto C,Daliberto Frugoli A,Fernando C,Aranha AC,Davidowicz H

更新日期：2012-01-01 00:00:00

abstract：:Application of a fiber optic biosensor (FOB) to the real-time investigation of the interaction kinetics between FITC-conjugated monoclonal sheep anti-human C-reactive protein (CRP) antibody and CRP isoforms on the surface of optical fiber is described. Recently, both the native pentameric CRP (pCRP), an acute phase pr...

journal_title：Journal of biomedical optics

authors： Chou C,Hsu HY,Wu HT,Tseng KY,Chiou A,Yu CJ,Lee ZY,Chan TS

更新日期：2007-03-01 00:00:00

abstract：SIGNIFICANCE:Spatial frequency domain imaging (SFDI) is an imaging modality that projects spatially modulated light patterns to determine optical property maps for absorption and reduced scattering of biological tissue via a pixel-by-pixel data acquisition and analysis procedure. Compressive sensing (CS) is a signal pr...

journal_title：Journal of biomedical optics

authors： Mellors BOL,Bentley A,Spear AM,Howle CR,Dehghani H

更新日期：2020-11-01 00:00:00

abstract：:The absorption of filter substances in sunscreens, reducing the incident ultraviolet (UV) radiation, is the basis for the protecting ability of such formulations. The erythema-correlated sun protection factor (SPF), depending mainly on the intensity of the UVB radiation, is the common value to quantify the efficacy of...

journal_title：Journal of biomedical optics

authors： Weigmann HJ,Schanzer S,Antoniou C,Sterry W,Lademann J

更新日期：2010-09-01 00:00:00

abstract：:The aim is to study cerebral vascular functional connectivity during motor tasks and resting state using multichannel frequency-domain near-infrared spectrophotometry. Maps of 5.7 × 10.8 cm size displaying changes in cerebral oxyhemoglobin (O(2)Hb), deoxyhemoglobin (HHb), and total hemoglobin (tHb) concentrations were...

journal_title：Journal of biomedical optics

authors： Wolf U,Toronov V,Choi JH,Gupta R,Michalos A,Gratton E,Wolf M

更新日期：2011-08-01 00:00:00

abstract：:By using a novel temporal characterization technique, we determined that a threshold average laser power of 160 mW is required to drill through a 0.75-mm-thick cortical bone for a Nd:YVO(4) mode-locked laser oscillator with a peak intensity of 1.3 GWcm(2). The ablation mechanism is identified as average-power induced ...

journal_title：Journal of biomedical optics

authors： Lee YM,Tu RY,Chiang AC,Huang YC

更新日期：2007-11-01 00:00:00

abstract：:Pedicle screw (PS) fixation has been widely used for spine diseases. Scientists and clinicians employ several approaches to navigate PS during operation. We have demonstrated the feasibility of monitoring the reduced scattering coefficient (μ's) on the trajectory of PS using near-infrared spectroscopy (NIRS). To perfo...

journal_title：Journal of biomedical optics

authors： Liu Y,Wang Y,Qian Z,Zhao J,Cao X,Li W

更新日期：2014-01-01 00:00:00

abstract：SIGNIFICANCE:In breast-preserving tumor surgery, the inspection of the excised tissue boundaries for tumor residue is too slow to provide feedback during the surgery. The discovery of positive margins requires a new surgery which is difficult and associated with low success. If the re-excision could be done immediately...

journal_title：Journal of biomedical optics

authors： Beletkaia E,Dashtbozorg B,Jansen RG,Ruers TJM,Offerhaus HL

更新日期：2020-09-01 00:00:00

abstract：:In this work experimental tissue phantoms and numerical models were developed to estimate photon migration through the fetal head in utero. The tissue phantoms incorporate a fetal head within an amniotic fluid sac surrounded by a maternal tissue layer. A continuous wave, dual-wavelength (lambda = 760 and 850 nm) spect...

journal_title：Journal of biomedical optics

authors： Vishnoi G,Hielscher AH,Ramanujam N,Chance B

更新日期：2000-04-01 00:00:00

abstract：:We demonstrate that doubly-resonant coherent anti-Stokes Raman scattering can provide enhanced and highly specific contrast for molecules containing unique Raman-active small molecular groups. This combination provides contrast for molecules that can otherwise be difficult to discriminate by Raman spectroscopy. Here, ...

journal_title：Journal of biomedical optics

authors： Weeks T,Schie I,den Hartigh LJ,Rutledge JC,Huser T

更新日期：2011-02-01 00:00:00

abstract：:The formation of kidney stones is a common and highly studied disease, which causes intense pain and presents a high recidivism. In order to find the causes of this problem, the characterization of the main compounds is of great importance. In this sense, the analysis of the composition and structure of the stone can ...

journal_title：Journal of biomedical optics

authors： Blanco F,López-Mesas M,Serranti S,Bonifazi G,Havel J,Valiente M

更新日期：2012-07-01 00:00:00

abstract：SIGNIFICANCE:In multiphoton microscopy, two-photon excited fluorescence (TPEF) spectra carry valuable information on morphological and functional biological features. For measuring these biomarkers, separation of different parts of the fluorescence spectrum into channels is typically achieved by the use of optical band...

journal_title：Journal of biomedical optics

authors： Meyer BO,Stella MPJ,Holst B,Nielsen BS,Holmstrøm K,Andersen PE,Marti D

更新日期：2020-07-01 00:00:00

abstract：:Protoporphyrin IX (PpIX)-encapsulated mesoporous silica nanoparticles were synthesized, characterized, and utilized for photodynamic therapy (PDT) of cancer. Silica encapsulation is relatively transparent for activated light and can protect the PpIX against denaturation induced by the extreme bioenvironment. The mesop...

journal_title：Journal of biomedical optics

authors： Qian J,Gharibi A,He S

更新日期：2009-01-01 00:00:00

abstract：:Second-harmonic-generation (SHG) microscopy has emerged as a powerful tool to image unstained living tissues and probe their molecular and supramolecular organization. In this article, we review the physical basis of SHG, highlighting how coherent summation of second-harmonic response leads to the sensitivity of polar...

journal_title：Journal of biomedical optics

authors： Vanzi F,Sacconi L,Cicchi R,Pavone FS

更新日期：2012-06-01 00:00:00

abstract：:An evolving area of biomedical research is related to the creation of implantable units that provide various possibilities for imaging, measurement, and the monitoring of a wide range of diseases and intrabody phototherapy. The units can be autonomic or built-in in some kind of clinically applicable implants. Because ...

journal_title：Journal of biomedical optics

authors： Sheinman V,Rudnitsky A,Toichuev R,Eshiev A,Abdullaeva S,Egemkulov T,Zalevsky Z

更新日期：2014-01-01 00:00:00

abstract：:This study introduces a single-channel optical video stereomicroscope based on a transparent rotating deflector (TRD) for high-resolution and high-magnification stereomicroscopy. The existing stereomicroscopes have some limitations, such as limited resolution and magnification, fixed optical channel, and the necessity...

journal_title：Journal of biomedical optics

authors： Radfar E,Park J,Jung B

更新日期：2016-12-01 00:00:00

abstract：:Previous works investigated a spectroscopic technique that offered a promising alternative to blood and breath assays for determining in vivo alcohol concentration. Although these prior works measured the dorsal forearm, we report the results of a 26-subject clinical study designed to evaluate the spectroscopic techni...

journal_title：Journal of biomedical optics

authors： Ridder TD,Hull EL,Ver Steeg BJ,Laaksonen BD

更新日期：2011-02-01 00:00:00

abstract：:This study investigates the precision and intraindividual variability of a clinical optical pachometer based on low-coherence reflectometry, which was used to measure the central thickness of a human cornea in vivo. The instrument, attached to a slit lamp, is a single mode fiber optic based Michelson interferometer wi...

journal_title：Journal of biomedical optics

authors： Bo Hnke M,Masters BR,Wa Lti R,Ballif JJ,Chavanne P,Gianotti R,Salathe RP

更新日期：1999-01-01 00:00:00

abstract：:A hyperspectral image projector (HIP) based on liquid crystal on silicon spatial light modulators is explained and demonstrated to generate data cubes. The HIP-constructed data cubes are three-dimensional images of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxyhemoglobi...

journal_title：Journal of biomedical optics

authors： Chon B,Tokumasu F,Lee JY,Allen DW,Rice JP,Hwang J

更新日期：2015-01-01 00:00:00