Abstract:
:Polyelectrolyte capsules are seen as promising nanotechnology based drug delivery systems. In previous works, we have demonstrated the possibility to fabricate bio-activated surface layer containing capsules with improved features in terms of biocompatibility. In this study, we have characterized the permeability properties of such capsules towards low and high molecular weight molecules, including proteins. The results indicated that the presence of the surface layer strongly affects the permeability properties of the capsules in terms of loading capacity which was found to be higher compared to that of plain capsules. These properties make such systems interesting candidates as drug delivery platforms.
journal_name
J Biomater Appljournal_title
Journal of biomaterials applicationsauthors
Habibi N,Pastorino L,Sandoval OH,Ruggiero Cdoi
10.1177/0885328212446358subject
Has Abstractpub_date
2013-08-01 00:00:00pages
262-9issue
2eissn
0885-3282issn
1530-8022pii
0885328212446358journal_volume
28pub_type
杂志文章abstract::The quality and quantity of bone are crucial to the success of dental implant treatment. Recently, bone grafting materials have reached some limitations. This study aimed to evaluate the biocompatibility of novel drug delivery material, injectable methacrylated hyaluronic acid hydrogel incorporated with different rati...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220971746
更新日期:2020-11-04 00:00:00
abstract::A multifunctional targeted nanoplatform combining photothermal therapy and chemotherapy has emerged as a promising strategy for comprehensive therapies of breast cancer. In this study, we constructed human epidermal growth factor receptor 2 (Her2)-targeted gold nanoshelled poly(lactic-co-glycolic acid) hybrid nanocaps...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220929616
更新日期:2020-09-01 00:00:00
abstract::At present all the commercially available "medical grade" urethane elastomers exhibit a phenomenon known as environmental stress cracking (ESC). This phenomenon is characterized by surface microcracking when the elastomer is elongated while in vivo. The degree of strain that is required to initiate microcracking varie...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829100600202
更新日期:1991-10-01 00:00:00
abstract:PURPOSE:A functionalized graphene oxide-based thermosensitive hydrogel loaded with docetaxel for intratumoral delivery was designed to enhance therapeutic efficacy and alleviate system toxicity. METHODS:First, graphene oxide was functionalized with chitosan to acquire high stability in physiological solutions. And the...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215619583
更新日期:2016-03-01 00:00:00
abstract::In this work, the role of shock wave-induced increase of bone morphogenetic proteins in modulating the osteogenic properties of osteoblast-like cells seeded on a bioactive scaffold was investigated using gremlin as a bone morphogenetic protein antagonist. Bone-like glass-ceramic scaffolds, based on a silicate experime...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328214541974
更新日期:2014-11-01 00:00:00
abstract::Appropriate design of dialysis membranes requires correct values of structural parameters such as pore radius, surface porosity, water content and tortuosity. It is impossible, however, to find the pore radius of dialysis membranes using a mercury porosimeter or an electron microscope because the pores are only severa...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532828900400201
更新日期:1989-10-01 00:00:00
abstract::The layer-by-layer technique, which allows simple preparation of polyelectrolyte multilayers, came into the focus of research for development of functionalized medical devices. Numerous literature exist that concentrate on the film build-up and the behaviour of cells on polyelectrolyte multilayers. However, in case of...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212437610
更新日期:2013-07-01 00:00:00
abstract::Poly(2-hydroxyethyl methacrylate) hydrogel intraocular lenses, containing adrenochrome-melanin, were manufactured and implanted in animal eyes in order to assess the effect of melanin upon (a) biocompatibility of implants with the eye tissues, and (b) fibrous proliferation of lens epithelium responsible for the opacif...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829500900305
更新日期:1995-01-01 00:00:00
abstract::Among biomaterials used as implants in human body, sutures constitute the largest groups of materials having a huge market exceeding $1.3 billion annually. Sutures are the most widely used materials in wound closure and have been in use for many centuries. With the development of the synthetic absorbable polymer, poly...
journal_title:Journal of biomaterials applications
pub_type: 历史文章,杂志文章,评审
doi:10.1177/0885328210384890
更新日期:2010-11-01 00:00:00
abstract::Injectable thermo-sensitive hydrogels have a potential application in bone tissue engineering for their sensitivities and minimal invasive properties. Human dental pulp stem cells have been considered a promising tool for tissue reconstruction. The objective of this study was to investigate the proliferation and osteo...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328216661566
更新日期:2016-09-01 00:00:00
abstract::The paper studies the coupling reaction by covalent bonding of acetylamino-2-sulfamoyl-1,3,4-thiodiazole (AcAA) on the poly(acrylic acid-costyrene) copolymer (PAcA-S) in homogeneous system, in the presence of dicyclohexylcarbodiimide (DCC) as activator. The influence of some factors on coupling efficiency (the drug/su...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829200700105
更新日期:1992-07-01 00:00:00
abstract::A range of crystalline and nano-sized carbonate- and silicate-substituted hydroxyapatite has been successfully produced by using continuous hydrothermal flow synthesis technology. Ion-substituted calcium phosphates are better candidates for bone replacement applications (due to improved bioactivity) as compared to pha...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212460289
更新日期:2013-09-01 00:00:00
abstract::The purpose of this investigation is to study the effect of long-term subcutaneous aluminum polymeric implants on aluminum release and accumulation in various tissues in rats. The implants were formulated using silicone rubber and polyurethane polymers and three different aluminum salts. The polymeric matrices were ev...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532829601100103
更新日期:1996-07-01 00:00:00
abstract::Osteo-odonto-keratoprostheses, incorporating dental laminate material as an anchoring skirt around a central poly(methyl methacrylate) (PMMA) optic, have been used to replace the cornea for many years. However, there are many intricacies associated with the use of autologous dental laminate material, surgical complexi...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328220972219
更新日期:2020-11-11 00:00:00
abstract::In the present study, a novel hydrogel-grafted fabrics embedding of berberine nanosuspension was developed for the treatment of infected wound. Hydrogel-grafted fabric was prepared by graft copolymerization of N-isopropylacrylamide and alginate using ceric ammonium nitrate as initiator. Berberine nanosuspension was pr...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328213509503
更新日期:2014-05-01 00:00:00
abstract::The aim of this study was to examine the release of silica (Si), calcium (Ca), phosphorous (P), and fluoride (F) from conventional glass ionomer cement (GI) and resin-modified glass ionomer cement (LCGI), containing different quantities of bioactive glass (BAG). Further aim was to evaluate in vitro biomineralization o...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0085328204044538
更新日期:2004-07-01 00:00:00
abstract::Antenna coupling microwave plasma enables a highly oxidative treatment of the outmost surface of polypropylene (PP) nonwoven fabric within a short time period. Subsequently, grafting copolymerization with acrylic acid (AAc) makes the plasma-treated fabric durably hydrophilic and excellent in water absorbency. With hig...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1106/088532802030478
更新日期:2002-10-01 00:00:00
abstract::In this study, the effects of sodium carbonate (Na(2)CO(3) ) solution with different concentrations (10, 15, 20, and 25 wt%) as liquid phase on the setting time and compressive strength of tricalcium silicate bone cements are investigated. The in vitro bioactivity and degradability of the resultant Ca(3)SiO(5)-Na(2)CO...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328208088714
更新日期:2008-11-01 00:00:00
abstract::Understanding the structure-function relationship in biomaterial constructs is critical in optimizing biological outcomes. For ensheathed structures such as peripheral nerve, engineering implantable tissue substitutes has been challenging. This is due to a unique geometry of thin-walled microtube arrays composed mostl...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328218804338
更新日期:2018-10-01 00:00:00
abstract::Functionalization of a porous orthopedic implant with dexamethasone, a widely used anti-inflammatory drug, encapsulated within a biodegradable polymer for controlled release could help reduce or eliminate the inflammation response by the local tissue. In this research, we investigated the possibility of using supercri...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328209354365
更新日期:2011-01-01 00:00:00
abstract::Calcium polyphosphate is a biodegradable bone substitute. It remains a challenge to prepare porous calcium polyphosphate with desired gradient porous structures. In this study, a modified one-step gravity sintering method was used to prepare calcium polyphosphate scaffolds with desired-gradient-pore-size distribution....
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215608335
更新日期:2016-02-01 00:00:00
abstract::Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/088532828700200305
更新日期:1988-01-01 00:00:00
abstract::The development of an effective wound dressing with the ability to induce skin wound healing is a great challenge in medicine. Nanofibers are highly attractive for wound dressing preparation due to their properties such as hemostasis induction, good absorption of wound exudates, and facilitation of cell growth. Chitos...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328217739562
更新日期:2018-01-01 00:00:00
abstract::Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328207079731
更新日期:2008-05-01 00:00:00
abstract::Engineered anisotropic tissue constructs containing aligned cell and extracellular matrix structures are useful as in vitro models and for regenerative medicine. They are of particular interest for nervous system modelling and regeneration, where tracts of aligned neurons and glia are required. The self-alignment of c...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215597818
更新日期:2015-11-01 00:00:00
abstract::Gold nanomaterials possess unique physical and chemical properties, which attracted much attention in recent years. As a new type of gold nanomaterials, gold nanostars (GNSTs) have been prepared and characterized in this study. GNSTs under near-infrared (NIR) light irradiation can exert not only cancer photothermal th...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215594481
更新日期:2015-11-01 00:00:00
abstract::Staphylococcus epidermidis plays a major role in capsular contractures of silicone breast implants. This in vitro study evaluates the antibacterial effect of copper on S. epidermidis in silicone implants. Specimens of a silicone material used for breast augmentation (Cu0) and specimens coated with different copper con...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328212441957
更新日期:2013-08-01 00:00:00
abstract::Nonviral gene delivery systems are finding widespread use due to their safety, rapid and economical production, and ease of modification. In this work, series of N-alkyl-substituted linear polyethylenimine (CP) polymers have been synthesized, characterized, and investigated about how degree of substitution (hydrophobi...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328217710125
更新日期:2017-07-01 00:00:00
abstract::The present article deals with the development of 3D porous scaffolds for bone grafting. They were prepared based on rapid fluid infiltration of Al2O3-SiO2 sol into a polyethylene non-woven fabric template structure. Titanium dioxide in concentration equal to 5 wt% was added to the Al2O3-SiO2 mixture to produce Al2O3-...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328213483634
更新日期:2014-02-01 00:00:00
abstract::To develop biocompatible composite microspheres for novel hemostatic use, we designed and prepared a novel biomaterial, composite microspheres consisting of carboxymethyl chitosan, sodium alginate, and collagen (CSCM). The ultra-structure of CSCM was investigated by scanning electron microscopy assay. In hemostatic fu...
journal_title:Journal of biomaterials applications
pub_type: 杂志文章
doi:10.1177/0885328215618354
更新日期:2016-02-01 00:00:00