Optimising contraction and alignment of cellular collagen hydrogels to achieve reliable and consistent engineered anisotropic tissue.

abstract：:The objective of this study is to evaluate the osteoconductivity and bioactivity of the Bonelike graft in repairing surgical cystic bone defects. Bonelike is implanted in 11 patients, aged between 24 and 53 years with a mean age of 36 years, consisting of 5 men and 6 women. According to the standard follow up protocol...

journal_title：Journal of biomaterials applications

authors： Sousa RC,Lobato JV,Maurício AC,Hussain NS,Botelho CM,Lopes MA,Santos JD

更新日期：2008-01-01 00:00:00

abstract：:The in vitro effect of platelet-rich plasma (PRP) on cell loading, proliferation, and osteogenic differentiation of human mesenchymal stem cells (MSC) is assessed on distinct resorbable and synthetic calcium phosphate scaffolds. A high specific surface area scaffold composed of calcium-deficient hydroxyapatite (CDHA; ...

journal_title：Journal of biomaterials applications

authors： Kasten P,Vogel J,Beyen I,Weiss S,Niemeyer P,Leo A,Lüginbuhl R

更新日期：2008-09-01 00:00:00

abstract：:The development and improvement of medical devices and artificial organs is critically dependent on the realisation of the importance of the interactions between materials and body tissues. In this regard, the evaluation of biocompatibility assumes paramount importance. This paper reviews the hematological aspects of ...

journal_title：Journal of biomaterials applications

authors： Banerjee R,Nageswari K,Puniyani RR

更新日期：1997-07-01 00:00:00

abstract：:Biodegradable magnesium-based implants are currently being developed for use in orthopedic applications. The aim of this study was to investigate the acute, subacute, and chronic local effects on bone tissue as well as the systemic reactions to a magnesium-based (MgYREZr-alloy) screw containing rare earth elements. Th...

journal_title：Journal of biomaterials applications

authors： Waizy H,Diekmann J,Weizbauer A,Reifenrath J,Bartsch I,Neubert V,Schavan R,Windhagen H

更新日期：2014-01-01 00:00:00

abstract：:Dicalcium phosphate dihydrate particles functionalized with triethyleneglycol dimethacrylate were synthesized and added to a photocurable mixture of bisphenol-A glycidyl dimethacrylate and triethyleneglycol dimethacrylate with the purpose of developing a resin composite capable of releasing calcium and phosphate ions ...

journal_title：Journal of biomaterials applications

authors： Rodrigues MC,Xavier TA,Arana-Chavez VE,Braga RR

更新日期：2017-01-01 00:00:00

abstract：:Magnesium-based alloys exhibit biodegradable, biocompatible and excellent mechanical properties which enable them to serve as ideal candidate biomedical materials. In particular, their biodegradable ability helps patients to avoid a second surgery. The corrosion rate, however, is too rapid to sustain the healing proce...

journal_title：Journal of biomaterials applications

authors： Chen Y,Dou J,Yu H,Chen C

更新日期：2019-05-01 00:00:00

abstract：:Phenylalanine ethyl ester (PAE)-alginate (Alg) conjugate (PAE-Alg, PEA) was synthesized and formation of an amide bond between PAE and Alg was confirmed by Fourier transformed-infrared and (1)H nuclear magnetic resonance spectroscopy. The degree of PAE substitution was 3.5-4.7 (PAE group per hundred sugar residues of ...

journal_title：Journal of biomaterials applications

authors： Zhang P,Zhao SR,Li JX,Hong L,Raja MA,Yu LJ,Liu CG

更新日期：2016-07-01 00:00:00

abstract：:The process of molecular self-assembly plays a crucial role in formulation of polymeric nanoparticulated drug delivery carriers as it creates the possibility for enhanced drug encapsulation and carrier surface engineering. This study aimed to develop a novel self-assembled polymeric micelles for targeted delivery in t...

journal_title：Journal of biomaterials applications

authors： Djurdjic B,Dimchevska S,Geskovski N,Petrusevska M,Gancheva V,Georgiev G,Petrov P,Goracinova K

更新日期：2015-01-01 00:00:00

abstract：:In this work, we report brushite-based calcium phosphate cement (CPC) system to enhance the in vivo biodegradation and tissue in-growth by incorporation of micro-channeled hydroxyapatite (HAp) granule and silicon and sodium addition in calcium phosphate precursor powder. Sodium- and silicon-rich calcium phosphate powd...

journal_title：Journal of biomaterials applications

authors： Sarkar SK,Lee BY,Padalhin AR,Sarker A,Carpena N,Kim B,Paul K,Choi HJ,Bae SH,Lee BT

更新日期：2016-01-01 00:00:00

abstract：:The layer-by-layer technique, which allows simple preparation of polyelectrolyte multilayers, came into the focus of research for development of functionalized medical devices. Numerous literature exist that concentrate on the film build-up and the behaviour of cells on polyelectrolyte multilayers. However, in case of...

journal_title：Journal of biomaterials applications

authors： Nolte A,Hossfeld S,Schroeppel B,Mueller A,Stoll D,Walker T,Wendel HP,Krastev R

更新日期：2013-07-01 00:00:00

abstract：:Polylactic acid (PLA)-derived polymers are widely used in many biotechnological fields, thanks to their biocompatibility and resorbability through natural pathways. Moreover, PLA is one of the few polymers in which both the properties and the stereochemical structure can be easily modified, making possible a specific ...

journal_title：Journal of biomaterials applications

authors： Renò F,Rizzi M,Cannas M

更新日期：2012-08-01 00:00:00

abstract：:The aim of the in vitro study was a comparison of an allogenic (ABSM) and a xenogenic bone substitute material (XBSM) with and without injectable platelet-rich fibrin (ABSM-i-PRF & XBSM-i-PRF) on cell characteristics of human osteoblasts (HOB). Here, ABSM and XBSM (+ i-PRF = test; - i-PRF = control) were incubated wit...

journal_title：Journal of biomaterials applications

authors： Kyyak S,Blatt S,Pabst A,Thiem D,Al-Nawas B,Kämmerer PW

更新日期：2020-07-01 00:00:00

abstract：:Melt electrowriting (MEW) can print high-resolution scaffolds with the ultrafine fibers from 800 nm to 20 µm. However, the cell seeding efficiency relatively low due to the large pore size of the MEW scaffold. Here, we reported a method to solve this dilemma by electrospinning a gelatin methacrylate (GelMA) hydrogel f...

journal_title：Journal of biomaterials applications

authors： Ye W,Xie C,Liu Y,He Y,Gao Q,Ouyang A

更新日期：2021-01-01 00:00:00

abstract：:Excessive demineralization in osteoporotic bones impairs its self-regeneration potential following a defect/fracture and is of great concern among the aged population. In this context, implants with inherent osteogenic ability loaded with therapeutic ions like Strontium (Sr2+) may bring forth promising outcomes. Micro...

journal_title：Journal of biomaterials applications

authors： Chandran S,Babu S S,Vs HK,Varma HK,John A

更新日期：2016-10-01 00:00:00

abstract：:Even though Ti-based implants are the most used materials for hard tissue replacement, they may present lack of osseointegration on the long term, due to their inertness. Hydrothermal treatment (HT) is a useful technique for the synthesis of firmly attached, highly crystalline coatings made of anatase titanium dioxide...

journal_title：Journal of biomaterials applications

authors： Lorenzetti M,Dakischew O,Trinkaus K,Lips KS,Schnettler R,Kobe S,Novak S

更新日期：2015-07-01 00:00:00

abstract：:In order to find hemodynamic parameters that can accurately predict whether patients can be successfully weaned from ventricular assist devices (VADs), we studied data from 17 patients supported with Pierce-Donachy VADs [11 left VAD (LVAD); 6 right VAD (RVAD)] following cardiogenic shock for periods from 1.3 to 22 day...

journal_title：Journal of biomaterials applications

authors： Termuhlen DF,Swartz MT,Ruzevich SA,Reedy JE,Pennington DG

更新日期：1990-04-01 00:00:00

abstract：:Eight different chemicals were investigated as potential candidate coupling agents for phosphate glass fibre reinforced polylactic acid composites. Evidence of reaction of the coupling agents with phosphate glass and their effect on surface wettability and glass degradation were studied along with their principle role...

journal_title：Journal of biomaterials applications

authors： Hasan MS,Ahmed I,Parsons AJ,Rudd CD,Walker GS,Scotchford CA

更新日期：2013-09-01 00:00:00

abstract：:Composite hydrogel systems consisting of oxidized alginate, gelatin, and biphasic calcium phosphate were fabricated by the Schiff-base reaction and the effect of oxidation of alginate on the microstructure, material properties, and biocompatibility were evaluated. Alginate was modified by oxidizing the attached -OH gr...

journal_title：Journal of biomaterials applications

authors： Nguyen TP,Lee BT

更新日期：2012-09-01 00:00:00

abstract：:Titanium and hydroxyapatite (HA) are widely used as biomaterials for dental and medical applications. HA-coated titanium implants have excellent biocompatibility and mechanical properties. However, the adherence of HA film formed on titanium substrate is weak because of the lack of chemical interaction between HA and ...

journal_title：Journal of biomaterials applications

authors： Inoue M,Rodriguez AP,Takagi T,Katase N,Kubota M,Nagai N,Nagatsuka H,Inoue M,Nagaoka N,Takagi S,Suzuki K

更新日期：2010-03-01 00:00:00

abstract：:The controlled release of insulin from a series of biodegradable hybrid hydrogel network containing dextran derivative of allyl isocyanate (dex-AI) and poly (D,L) lactide diacrylate macromer (PDLLAM) over a wide range of composition ratio was investigated. Laser confocal scanning microscope was used to understand the ...

journal_title：Journal of biomaterials applications

authors： Zhang Y,Chu CC

更新日期：2002-04-01 00:00:00

abstract：:Herb borneol is usually used in clinics for the treatment of central nervous system illness, for its ability of blood-brain barrier permeability, although its poor water solubility and poor bioavailability limit its clinical application to some degree. In this study, we developed a novel nanoparticle combining the ben...

journal_title：Journal of biomaterials applications

authors： Liu Y,Rao L,Zhang H,Cen Y,Cheng K

更新日期：2018-10-01 00:00:00

abstract：:Among biomaterials used as implants in human body, sutures constitute the largest groups of materials having a huge market exceeding $1.3 billion annually. Sutures are the most widely used materials in wound closure and have been in use for many centuries. With the development of the synthetic absorbable polymer, poly...

journal_title：Journal of biomaterials applications

authors： Pillai CK,Sharma CP

更新日期：2010-11-01 00:00:00

abstract：:This study's aim consists of evaluating the adhesion and proliferation of mesenchymal stem cells (MSCs) derived from rat bone marrow on nanoparticle Titanium (Ti) surface. Hence, passage 3 MSCs were, respectively, seeded on nanoparticle Ti and pure Ti surfaces and then cultured for 32 h. Cell morphology and viability ...

journal_title：Journal of biomaterials applications

authors： Chen L,Sun J,Zhu Z,Wu K,Li W,Liu H,Xu S

更新日期：2013-01-01 00:00:00

abstract：:Two series of glasses of general formula (2-p) SiO2.1.1Na2O.CaO.pP2O5.xZnO (p=0.10, 0.20; x=0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chemical surface features before and after contact with simulated body fluid, morphological characteristics, and osteoblast-like cells behavior when cultured on them. Th...

journal_title：Journal of biomaterials applications

authors： Lusvardi G,Malavasi G,Menabue L,Menziani MC,Pedone A,Segre U,Aina V,Perardi A,Morterra C,Boccafoschi F,Gatti S,Bosetti M,Cannas M

更新日期：2008-05-01 00:00:00

abstract：:Type 1 diabetes mellitus is a serious disease comprising approximately 10% of all diabetes cases, and the global incidence of type 1 diabetes mellitus is steadily rising without any promise of a cure in the near future. Although islet transplantation has proven to be an effective means of treating type 1 diabetes mell...

journal_title：Journal of biomaterials applications

authors： Xu L,Guo Y,Huang Y,Xu Y,Lu Y,Wang Z

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:A functionalized graphene oxide-based thermosensitive hydrogel loaded with docetaxel for intratumoral delivery was designed to enhance therapeutic efficacy and alleviate system toxicity. METHODS:First, graphene oxide was functionalized with chitosan to acquire high stability in physiological solutions. And the...

journal_title：Journal of biomaterials applications

authors： Zhu X,Zhang Y,Huang H,Zhang H,Hou L,Zhang Z

更新日期：2016-03-01 00:00:00

abstract：:Nanodrug delivery systems have been widely researched to achieve efficient antitumor drug delivery. However, the controlled drug delivery at tumor cells remains the main challenge for antitumor therapy. Herein, a pH and reduction-responsive nanocarrier based on green tea polyphenols was employed as a smart excipient f...

journal_title：Journal of biomaterials applications

authors： Guo Z,Yang Y,Shu Y,Qiao L,Peng M,Wang Z

更新日期：2020-08-01 00:00:00

abstract：:Sustained intestinal delivery of thiamine hydrochloride (Vitamin B(1); VB(1)) and pyridoxine hydrochloride (Vitamin B(6); VB(6)) seems to be a feasible alternative to existing therapy. The vitamins (VB(1)/VB(6)) intercalated in montmorillonite (MMT) and intercalated VB(1)/VB(6)-MMT hybrid is further used for synthesis...

journal_title：Journal of biomaterials applications

authors： Kevadiya BD,Joshi GV,Patel HA,Ingole PG,Mody HM,Bajaj HC

更新日期：2010-08-01 00:00:00

abstract：:The aim of the paper is to obtain and characterize k-carrageenan-chitosan dual hydrogel multilayers shell BSA gel microcapsules, as a carrier for curcumin, and as a possible antitumoral agent in biological studies. We used the CaCO3 template to synthesize non-toxic CaCO3/BSA particles as microtemplates by coprecipitat...

journal_title：Journal of biomaterials applications

authors： Paşcalău V,Soritau O,Popa F,Pavel C,Coman V,Perhaita I,Borodi G,Dirzu N,Tabaran F,Popa C

更新日期：2016-01-01 00:00:00

abstract：:In order to induce esophageal muscle cells' orientation, the silicon wafer with prototype 1 and prototype 2 was designed. Prototype 1 has micro-channels of 200 µm width and 30 µm depth with 30 µm wide wall as the interval. Prototype 2 has channels of 100 µm width and 30 µm depth with a discontinuous wall which has 30 ...

journal_title：Journal of biomaterials applications

authors： Hou L,Gong C,Zhu Y

更新日期：2016-04-01 00:00:00