Abstract：
:Bacterial pathogens are dependent on virulence factors to efficiently colonize and propagate within their hosts. Many Gram-negative bacterial pathogens rely on specialized proteinaceous secretion systems that inject virulence factors, termed effectors, directly into host cells. These bacterial effector proteins perform various functions within host cells; however, regulation of their function within the host cell is highly enigmatic. It is becoming increasingly apparent that many of these effectors directly influence and regulate each other and their mechanisms within the host cell. We discuss the emerging theme of bacterial effector interplay impacting infection and the importance of investigating this topic.
journal_name
Trends Microbioljournal_title
Trends in microbiologyauthors
Shames SR,Finlay BBdoi
10.1016/j.tim.2012.02.007subject
Has Abstractpub_date
2012-05-01 00:00:00pages
214-9issue
5eissn
0966-842Xissn
1878-4380pii
S0966-842X(12)00039-Xjournal_volume
20pub_type
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