Abstract：
:Seasonal influenza is controlled through vaccination campaigns. Evolution of influenza virus antigens means that vaccines must be updated to match novel strains, and vaccine effectiveness depends on the ability of scientists to predict nearly a year in advance which influenza variants will dominate in upcoming seasons. In this review, we highlight a promising new surveillance tool: predictive models. Based on data-sharing and close collaboration between the World Health Organization and academic scientists, these models use surveillance data to make quantitative predictions regarding influenza evolution. Predictive models demonstrate the potential of applied evolutionary biology to improve public health and disease control. We review the state of influenza predictive modeling and discuss next steps and recommendations to ensure that these models deliver upon their considerable biomedical promise.
journal_name
Trends Microbioljournal_title
Trends in microbiologyauthors
Morris DH,Gostic KM,Pompei S,Bedford T,Łuksza M,Neher RA,Grenfell BT,Lässig M,McCauley JWdoi
10.1016/j.tim.2017.09.004subject
Has Abstractpub_date
2018-02-01 00:00:00pages
102-118issue
2eissn
0966-842Xissn
1878-4380pii
S0966-842X(17)30209-3journal_volume
26pub_type
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journal_title：Trends in microbiology
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doi：10.1016/s0966-842x(00)89000-9
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journal_title：Trends in microbiology
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journal_title：Trends in microbiology
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pub_type： 杂志文章,评审
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journal_title：Trends in microbiology
pub_type： 杂志文章,评审
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journal_title：Trends in microbiology
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doi：10.1016/j.tim.2013.04.006
更新日期：2013-07-01 00:00:00
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journal_title：Trends in microbiology
pub_type： 杂志文章,评审
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journal_title：Trends in microbiology
pub_type： 杂志文章,评审
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更新日期：2021-01-05 00:00:00
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journal_title：Trends in microbiology
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journal_title：Trends in microbiology
pub_type： 杂志文章,评审
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abstract：:The existence of peptidoglycan (PG) in chlamydiae has long been debated. Genome sequencing of members of the Chlamydiaceae family and Protochlamydia amoebophila has uncovered a nearly complete pathway for PG synthesis in these organisms. The recent use of microarray and proteomic analysis methods has revealed that PG ...
journal_title：Trends in microbiology
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journal_title：Trends in microbiology
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abstract：:Phosphite, a species of phosphorus in a P3+ oxidation state, is believed to have played an important role in the primordial Earth. Figueroa et al. used metagenomics to uncover anaerobic bacterial communities from waste water waste sludge that sustain life from energy provided by phosphite. ...
journal_title：Trends in microbiology
pub_type： 评论,杂志文章
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abstract：:Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and immune defenses, thus resulting in the establishment of infection. The best-characterized system mediating bacterial protein delivery into target eukaryotic cells is the type III secretion system (T3SS) expressed by Gram-negative bact...
journal_title：Trends in microbiology
pub_type： 杂志文章,评审
doi：10.1016/j.tim.2018.01.010
更新日期：2018-04-01 00:00:00
