Galectin-3 in cord blood of term and preterm infants.

abstract：:The functional integrity of the local immune system in vitamin A-deficient (A-) rats was investigated. Secretory IgA levels in the intestinal fluid of A- rats were significantly lower than in controls. This and the decrease in intensity of immunofluorescent staining for secretory component (SC) in the intestinal cells...

journal_title：Clinical and experimental immunology

authors： Sirisinha S,Darip MD,Moongkarndi P,Ongsakul M,Lamb AJ

更新日期：1980-04-01 00:00:00

abstract：:Maternal transmission of islet autoantibodies to children born to mothers with type 1 diabetes (T1D) has been shown to protect from autoantibodies and diabetes development later in life. However, the factors conferring disease protection are poorly understood. The aim of this study was to evaluate comparatively proinf...

journal_title：Clinical and experimental immunology

authors： Holm BC,Svensson J,Akesson C,Arvastsson J,Ljungberg J,Lynch K,Ivarsson SA,Lernmark A,Cilio CM,Diabetes Prediction Study in Skåne (DiPiS).

更新日期：2006-12-01 00:00:00

abstract：:Vitamin B2 and flavin cofactors are transported tightly bound to immunoglobulin in human serum. We reasoned that anti-mitochondrial flavoprotein autoantibodies (alpha Fp-AB) present in the serum of patients with myocarditis and cardiomyopathy of unknown aetiology may form immunoglobulin aggregates with these serum pro...

journal_title：Clinical and experimental immunology

authors： Stähle I,Brizzio C,Barile M,Brandsch R

更新日期：1999-03-01 00:00:00

abstract：:Peripheral leucocytes and platelets from twenty healthy volunteers were incubated in vitro with radiographic contrast media (diatrizoate-Hypaque, iothalamate-Conray and iodipamide-Cholografin) under varying conditions. All radiographic contrast media (RCM) were able to induce histamine release from peripheral leucocyt...

journal_title：Clinical and experimental immunology

authors： Ring J,Arroyave CM,Frizler MJ,Tan EM

更新日期：1978-04-01 00:00:00

abstract：:Recently we reported the first known incidence of antibodies possessing catalytic sialidase activity (sialidase abzymes) in the serum of patients with multiple myeloma and systemic lupus erythematosus (SLE). These antibodies desialylate biomolecules, such as glycoproteins, gangliosides and red blood cells. Desialylati...

journal_title：Clinical and experimental immunology

authors： Tomin A,Dumych T,Tolstyak Y,Kril I,Mahorivska I,Bila E,Stoika R,Herrmann M,Kit Y,Bilyy R

更新日期：2015-01-01 00:00:00

abstract：:Members of the European Society for Immunodeficiencies (ESID) and other colleagues have updated the multi-stage expert-opinion-based diagnostic protocol for non-immunologists incorporating newly defined primary immunodeficiency diseases (PIDs). The protocol presented here aims to increase the awareness of PIDs among d...

journal_title：Clinical and experimental immunology

authors： de Vries E,European Society for Immunodeficiencies (ESID) members.

更新日期：2012-01-01 00:00:00

abstract：:The expression of HLA class II glycoproteins by monocytes from HIV-infected individuals was evaluated. We found no differences in HLA-DR, HLA-DQ, or HLA-DP expression by freshly isolated monocytes from patients with clinical AIDS, HIV-infected patients without AIDS or from uninfected individuals. However, monocytes fr...

journal_title：Clinical and experimental immunology

authors： Zwilling BS,Darrow R,Mcpeek M,Laufman H,Pearl D

更新日期：1990-12-01 00:00:00

abstract：:Serum from 98 Thai adults infected with Plasmodium falciparum were examined for the presence of autoantibodies. Malarial containing antibodies sera were also revealed positive for anti-nuclear antibodies with fluorescence speckled pattern, anti-smooth muscle antibodies, anti-mitochondria antibodies and rheumatoid fact...

journal_title：Clinical and experimental immunology

authors： Boonpucknavig S,Ekapanyakul G

更新日期：1984-10-01 00:00:00

abstract：:Systemic capillary leak syndrome (SCLS) is a rare disease characterized by episodes of collapse due to rapid transfer of considerable volumes of plasma from the intravascular to the extravascular compartment. The pathogenesis of this disease is unknown. The diagnosis is made largely on clinical grounds, and investigat...

journal_title：Clinical and experimental immunology

authors： Zhang W,Ewan PW,Lachmann PJ

更新日期：1993-09-01 00:00:00

abstract：:Monoclonal antibodies were produced using mice immunized with the human promyeloid cell line HL60. Two antibodies are described which identify antigens selectively expressed by myeloid cells. Studies using normal bone marrow and myeloid leukaemia cells demonstrated that one of these antibodies (AGF4.48) identifies an ...

journal_title：Clinical and experimental immunology

authors： Fisher AG,Bunce CM,Toksoz D,Stone PC,Brown G

更新日期：1982-11-01 00:00:00

abstract：:Hybridomas producing monoclonal antibodies that bind to determinants on myelogenous leukaemia blast cells were developed using fresh leukaemia blasts as immunogens. These monoclonal antibodies were used to quantitate the amount of a variety of antigens on both leukaemia and normal blood cells in a radioimmunoassay. Th...

journal_title：Clinical and experimental immunology

authors： Ball ED,Fanger MW

更新日期：1982-06-01 00:00:00

abstract：:Two DNA-binding monoclonal antibodies (MoAb) derived from lupus mice were examined for their effects on kidney function. Antibody IV-228, reactive with single-stranded DNA (ssDNA) but not double-stranded DNA (dsDNA) significantly altered kidney function in some MRL/Mp-lpr/lpr (MRL/lpr) mice with lupus glomerulonephrit...

journal_title：Clinical and experimental immunology

authors： Lake RA,Staines NA

更新日期：1988-07-01 00:00:00

abstract：:Inadequate apoptosis may contribute to the synovial hyperplasia associated with rheumatoid arthritis (RA). The Fas-associated death domain protein (FADD)-like interleukin (IL)-1beta-converting enzyme (FLICE)-inhibitory protein (FLIP), which is an apoptotic inhibitor, has been implicated in the resistance to Fas-mediat...

journal_title：Clinical and experimental immunology

authors： Kim WU,Yoo SA,Min SY,Park SH,Koh HS,Song SW,Cho CS

更新日期：2006-06-01 00:00:00

abstract：:Although both envelope glycoproteins of the hepatitis C virus, E1 and E2/NS1, show a high degree of sequence variation, the E1 protein includes a well conserved domain, which may be functionally important. We have analysed the human B cell response to a peptide fragment from amino acid residues 314-330 (EP3) covering ...

journal_title：Clinical and experimental immunology

authors： Siemoneit K,Cardoso Mda S,Koerner K,Wölpl A,Kubanek B

更新日期：1995-08-01 00:00:00

abstract：:Anti-idiotypic antibodies (anti-Id Abs) are involved in the regulation of a number of immune responses including the IgE antibody production. In atopic patients, the increased synthesis of IgE antibodies could be related to a defective production of regulatory anti-Id Abs. In the present study, we first developed a se...

journal_title：Clinical and experimental immunology

authors： Hébert J,Bernier D,Mourad W

更新日期：1990-06-01 00:00:00

abstract：:The BB rat is a well-known animal model for the study of autoimmune thyroid disease. Antithyroglobulin antibodies can be detected in the circulation from the age of 6 weeks onwards, and accumulations of lymphoid cells occurs in the thyroid of up to 60% of animals at the age of 20 weeks and over. The rat, however, stay...

journal_title：Clinical and experimental immunology

authors： Voorby HA,Van der Gaag RD,Jeucken PH,Bloot AM,Drexhage HA

更新日期：1989-05-01 00:00:00

abstract：:Patients with common variable immunodeficiency (CVID) have reduced numbers and frequencies of dendritic cells (DCs) in blood, and there is also evidence for defective activation through Toll-like receptors (TLRs). Collectively, these observations may point to a primary defect in the generation of functional DCs. Here,...

journal_title：Clinical and experimental immunology

authors： Taraldsrud E,Fevang B,Aukrust P,Beiske KH,Fløisand Y,Frøland S,Rollag H,Olweus J

更新日期：2014-03-01 00:00:00

abstract：:Organ transplantation is the treatment of choice for patients with end-stage organ failure, but chronic immunosuppression is taking its toll in terms of morbidity and poor efficacy in preventing late graft loss. Therefore, a drug-free state would be desirable where the recipient permanently accepts a donor organ while...

journal_title：Clinical and experimental immunology

authors： Mahr B,Wekerle T

更新日期：2017-08-01 00:00:00

abstract：:During pathogenesis of diabetes, pancreatic islets are exposed to high levels of cytokines and other inflammatory mediators that induce deterioration of insulin-producing beta cells. Macrophage migration inhibitory factor (MIF) plays a key role in the onset and development of several immunoinflammatory diseases and al...

journal_title：Clinical and experimental immunology

authors： Stojanovic I,Saksida T,Nikolic I,Nicoletti F,Stosic-Grujicic S

更新日期：2012-08-01 00:00:00

abstract：:Antibody response and antigen specific suppression to bovine serum albumin (BSA) in uremic rats have been investigated. Primary immune response was found to be significantly reduced independent of the route of administration or adjuvant while secondary response was affected only in animals in which a weak adjuvant suc...

journal_title：Clinical and experimental immunology

authors： Mezzano S,Pesce A,Peters T Jr,Pollak VE,Reed R,Michael G

更新日期：1982-04-01 00:00:00

abstract：:The tryptic FAD-peptide carrying the flavin in 8alpha-(N3)histidyl linkage as natural hapten was isolated by HPLC from the bacterial enzyme 6-hydroxy-d-nicotine oxidase. The same flavin protein linkage is found in the mitochondrial succinate dehydrogenase flavoprotein subunit, the predominant flavoprotein with covalen...

journal_title：Clinical and experimental immunology

authors： Cicek G,Schiltz E,Staiger J,Neumann FJ,Melchers I,Brandsch R

更新日期：2003-05-01 00:00:00

abstract：:We used three-colour cytometry to analyse intracellular cytokine production in activated whole blood cultures derived from patients with HIV-1 infection. We assessed mitogen-induced IL-2, IL-4 and IFN-gamma production from T cells as possible markers of immune dysfunction. The percentages of T cells staining for IL-2 ...

journal_title：Clinical and experimental immunology

authors： Westby M,Marriott JB,Guckian M,Cookson S,Hay P,Dalgleish AG

更新日期：1998-02-01 00:00:00

abstract：:We previously demonstrated that high levels of IL-6/sIL-6R complexes are present in sera of patients with systemic juvenile idiopathic arthritis (s-JIA) and that the amount of IL-6 estimated in the IL-6/sIL-6R complexes is markedly higher than that measured by the B9 assay. Here, we show that two additional bioassays,...

journal_title：Clinical and experimental immunology

authors： Pignatti P,Ciapponi L,Galle P,Hansen MB,Massa M,Meazza C,Paonessa G,Novick D,Ciliberto G,Martini A,De Benedetti F

更新日期：2003-02-01 00:00:00

abstract：:Factors involved in the production of autoimmune thyroiditis in thymectomized and sublethally irradiated rats were investigated. The study suggested that a gene linked to RT1 of the rat major histocompatibility complex (MHC), a selective depletion of suppressor T cells and high radiosensitivity of the thyroid gland we...

journal_title：Clinical and experimental immunology

authors： Kotani T,Komuro K,Yoshiki T,Itoh T,Aizawa M

更新日期：1981-08-01 00:00:00

abstract：:Calculated globulin (total protein - albumin) is usually tested as part of a liver function test profile in both primary and secondary care and determines the serum globulin concentration, of which immunoglobulins are a major component. The main use hitherto of calculated globulin is to detect paraproteins when the le...

journal_title：Clinical and experimental immunology

authors： Jolles S,Borrell R,Zouwail S,Heaps A,Sharp H,Moody M,Selwood C,Williams P,Phillips C,Hood K,Holding S,El Shanawany T

更新日期：2014-09-01 00:00:00

abstract：:Experimental autoimmune hepatitis (EAH) is an animal model for autoimmune hepatitis. The disease is T cell-mediated and runs a subacute course, with maximal disease activity around week four after disease induction and a slow ensuing recovery. The aim of the present study was to investigate the immunoregulatory mechan...

journal_title：Clinical and experimental immunology

authors： Lohse AW,Meyer zum Büschenfelde KH

更新日期：1993-10-01 00:00:00

abstract：:Twelve patients, ten with common variable hypogammaglobulinaemia and two with hypogammaglobulinaemia secondary to chronic lymphocytic leukaemia (CLL), have been taught to self-infuse their intravenous immunoglobulin replacement therapy. Follow-up of these patients has shown that regular self-infusion at home is feasib...

journal_title：Clinical and experimental immunology

authors： Chapel H,Brennan V,Delson E

更新日期：1988-07-01 00:00:00

abstract：:During routine immunofluorescence studies of the serum of a patient with Sjögren's syndrome and lymphoma we detected antibodies giving a cytoplasmic pattern which did not correspond to previously described patterns found for autoantibodies. Using different cells and tissues as substrates for indirect immunofluorescenc...

journal_title：Clinical and experimental immunology

authors： Rodríguez JL,Gelpi C,Thomson TM,Real FJ,Fernández J

更新日期：1982-09-01 00:00:00

abstract：:CFA is an inflammatory condition of the lungs resulting in scarring, pulmonary failure and death. The etiology of the disease is unknown, but the pathogenesis is believed to involve a persistent immunological reaction to unidentified antigen in the lung resulting in tissue damage. Recent advances in our understanding ...

journal_title：Clinical and experimental immunology

authors： Wallace WA,Ramage EA,Lamb D,Howie SE

更新日期：1995-09-01 00:00:00

abstract：:The requirement for specificity of antibody-dependent inhibition or killing of intracellular Toxoplasma gondii trophozoites by normal mouse peritoneal macrophages was evaluated in vitro using light microscopy and autoradiography. Anti-toxoplasma antibody in the presence of 'accessory factor' rendered extracellular T. ...

journal_title：Clinical and experimental immunology

authors： Anderson SE Jr,Bautista SC,Remington JS

更新日期：1976-12-01 00:00:00