HLA class II glycoprotein expression by monocytes from HIV-infected individuals: differences in response to interferon-gamma.

abstract：:The murine antibody response to porcine insulin is controlled by immune response genes of the major histocompatibility complex. Animals of the one haplotype (H-2d) produce specific antibodies to pork insulin, while animals of other haplotypes do not. We analysed the antibody responses to purified pork insulin by anima...

journal_title：Clinical and experimental immunology

authors： Strayer DS,Kapp J

更新日期：1982-01-01 00:00:00

abstract：:Serum IgG subclasses and IgG, IgA and IgM were measured in 47 patients with chronic respiratory tract infection, 53 patients with recurrent acute respiratory infections and 66 healthy normal adults. Compared to the healthy control group, mean serum IgG2 was significantly lower in patients with chronic infection (P les...

journal_title：Clinical and experimental immunology

authors： Stanley PJ,Corbo G,Cole PJ

更新日期：1984-12-01 00:00:00

abstract：:In order to study the role of gamma/delta T cells in the pathogenesis of inflammatory bowel disease (IBD) in humans, we measured the percentage of these cells in the peripheral blood, assessed the ratio of the non-disulphide-linked (delta TCS1) type of T cell receptor (TCR) in the total gamma/delta T cells, studied th...

journal_title：Clinical and experimental immunology

authors： Giacomelli R,Parzanese I,Frieri G,Passacantando A,Pizzuto F,Pimpo T,Cipriani P,Viscido A,Caprilli R,Tonietti G

更新日期：1994-10-01 00:00:00

abstract：:Cytoplasmic free Ca2+ concentration and influx of 86Rb+ (K+ analogue) were determined during the first minutes after stimulation of neoplastic human B cells and B cell lines by antibodies to surface Ig. The Ca2+ concentration increased in the great majority of samples (41 of 48). All of four B cell lines also responde...

journal_title：Clinical and experimental immunology

authors： Heikkilä R,Ruud E,Funderud S,Godal T

更新日期：1985-03-01 00:00:00

abstract：:Suppression of the lymphocyte response to concanavalin A (Con A), phytohaemagglutinin (PHA) and protein A from Staphylococcus aureus (SpA) by Con A-induced suppressor cells was measured in twenty-four patients with recently active-recovering multiple sclerosis (MS), twelve with inactive MS and twenty-three healthy con...

journal_title：Clinical and experimental immunology

authors： Gonzalez RL,Dau PC,Spitler LE

更新日期：1979-04-01 00:00:00

abstract：:Recently we described the occurrence of B cells producing polyspecific natural IgM with anti-tumour specificity in the spleen of non-tumour-bearing individuals as well as in fetal organisms. Immunoprecipitation and 2-D electrophoresis showed the binding of such antibodies to a 55-kD (pI 6.0) membrane surface glycoprot...

journal_title：Clinical and experimental immunology

authors： Bohn J,Niemann B,Roggenbuck D,Döcke W,Jahn S

更新日期：1995-03-01 00:00:00

abstract：:The lymphokine profiles were determined in the skin lesions of the three distinct clinical forms of American cutaneous leishmaniasis (ACL), using a reverse transcriptase polymerase chain reaction (RT-PCR) and primers for various lymphokines. The message for interferon-gamma (IFN-gamma), tumour necrosis factor-beta (TN...

journal_title：Clinical and experimental immunology

authors： Cáceres-Dittmar G,Tapia FJ,Sánchez MA,Yamamura M,Uyemura K,Modlin RL,Bloom BR,Convit J

更新日期：1993-03-01 00:00:00

abstract：:Chronic bone infection is associated with bone resorption. From animal studies, CD3/CD28-activated T cells are known to enhance osteoclastogenesis and bone resorption. Because CD28 is expressed constitutively on T cells and its expression is down-regulated by chronic exposure to the inflammatory environment, we charac...

journal_title：Clinical and experimental immunology

authors： Kumar G,Roger PM,Ticchioni M,Trojani C,Bernard de Dompsur R,Bronsard N,Carles M,Bernard E

更新日期：2014-04-01 00:00:00

abstract：:The intestinal population of gamma delta T cell receptor (TCR)-bearing cells was characterized with regard to V delta and V gamma subtype expression. For this purpose, we utilized V gene-specific PCR of mRNA prepared from intestinal biopsies. Predominant expression of the V delta 1 subtype was demonstrated in the smal...

journal_title：Clinical and experimental immunology

authors： Bucht A,Söderström K,Esin S,Grunewald J,Hagelberg S,Magnusson I,Wigzell H,Grönberg A,Kiessling R

更新日期：1995-01-01 00:00:00

abstract：:A rabbit antiserum has been prepared using peripheral mononuclear cells from a patient with common variable hypogammaglobulinaemia (CVH) who had demonstrable suppressor cells in vitro. This antiserum (anti-Ck), after absorption with pooled normal glass-non-adherent cells and platelets, showed selective reactivity with...

journal_title：Clinical and experimental immunology

authors： Rizzoli AJ,Bankhurst AD

更新日期：1981-12-01 00:00:00

abstract：:Erythrocyte C3b receptors (ECR1) have been measured in 122 pairs of twins (60 monozygotic, 62 dizygotic) using an [125I]-labelled monoclonal antibody (E11). The range of ECR1 numbers was wide, 99-4179 sites/cell, with a log-normal distribution around a geometric mean of 837 sites/cell. The intra-pair variance in dizyg...

journal_title：Clinical and experimental immunology

authors： Fyfe A,Holme ER,McKay IC,Zoma A,Hunter J,Lucie NP,Whaley K

更新日期：1987-10-01 00:00:00

abstract：:We have examined the prevalence of circulating immune complexes in sera from patients with mycobacterial infections. Sera from 68 percent of patients with active M. tuberculosis and 58 percent of patients with M. intracellulare infections had significantly elevated Clq binding activity (Clq-BA). In general there was a...

journal_title：Clinical and experimental immunology

authors： Carr RI,Chakraborty AK,Brunda MJ,Davidson PT,Damle PB,Hardtke MA,Gilbride KJ,Minden P

更新日期：1980-03-01 00:00:00

abstract：:Nickel (Ni), the main cause of contact allergy to metals, induces in vitro production of both Th1- and Th2-type cytokines in peripheral blood mononuclear cells (PBMC) from allergic subjects. Because the knowledge of the cellular immune response to other metals involved in contact allergy has been limited, we investiga...

journal_title：Clinical and experimental immunology

authors： Minang JT,Areström I,Troye-Blomberg M,Lundeberg L,Ahlborg N

更新日期：2006-12-01 00:00:00

abstract：:The relationship between allergic airway inflammation and pneumococcal pneumonia is not well understood. We assessed susceptibility to experimental pneumococcal pneumonia in mice with and without allergic airway inflammation. Susceptibility to pneumococcal pneumonia was evaluated by challenging mice with a bioluminesc...

journal_title：Clinical and experimental immunology

authors： Kang CI,Rouse MS,Patel R,Kita H,Juhn YJ

更新日期：2009-06-01 00:00:00

abstract：:Monocytes (MO) migrating into normal, non-inflamed intestinal mucosa undergo a specific differentiation resulting in a non-reactive, tolerogenic intestinal macrophage (IMAC). Recently we demonstrated the differentiation of MO into an intestinal-like macrophage (MAC) phenotype in vitro in a three-dimensional cell cultu...

journal_title：Clinical and experimental immunology

authors： Spoettl T,Hausmann M,Herlyn M,Gunckel M,Dirmeier A,Falk W,Herfarth H,Schoelmerich J,Rogler G

更新日期：2006-07-01 00:00:00

abstract：:The anti-lymphocyte autoantibody response to irradiated lethal Plasmodium berghei malaria parasites in normal mice was significantly reduced when recipients were pre-treated with splenic T cells from mice recovered from a non-lethal Plasmodium yoelii infection. Suppression was specific for the autoantibody and did not...

journal_title：Clinical and experimental immunology

authors： de Souza JB,Playfair JH

更新日期：1983-10-01 00:00:00

abstract：:The contribution of circulating anti-La(SS-B) antibody to the hypergammaglobulinaemia seen in primary Sjögren's syndrome is unknown. In this study levels of anti-La(SS-B) antibody directed against three immunodominant epitopes of the anti-La(SS-B) autoantigen were measured by ELISA in 84 anti-La(SS-B)+ sera using puri...

journal_title：Clinical and experimental immunology

authors： Gordon TP,Greer M,Reynolds P,Guidolin A,McNeilage LJ

更新日期：1991-09-01 00:00:00

abstract：:Serum levels and liver expression of CCL2 are increased in patients with alcoholic hepatitis (AH). In an experimental model of alcoholic liver disease (ALD), CCL2 was implicated in proinflammatory cytokines activation and hepatic lipid metabolism, but its role in human disease is currently unknown. In a large cohort o...

journal_title：Clinical and experimental immunology

authors： Degré D,Lemmers A,Gustot T,Ouziel R,Trépo E,Demetter P,Verset L,Quertinmont E,Vercruysse V,Le Moine O,Devière J,Moreno C

更新日期：2012-09-01 00:00:00

abstract：:Chronic, remittent, erosive arthritis was produced in rats by a single intraperitoneal injection of an aqueous suspension of cell wall fragments isolated from group A streptococci. Arthritis could be induced in rats which had been immunologically compromised by neonatal thymectomy. Delayed hypersensitivity to cell wal...

journal_title：Clinical and experimental immunology

authors： Hunter N,Anderle SK,Brown RR,Dalldorf FG,Clark RL,Cromartie WJ,Schwab JH

更新日期：1980-12-01 00:00:00

abstract：:Antibody-dependent cellular cytotoxicity (ADCC) was investigated as s possible mechanism of pathogenesis in recurrent aphthous ulceration (RAU). ADCC induced by mononuclear cells from patients at various stages of RAU was compared with ADCC induced by mononuclear cells from paired controls. Chicken red blood cells (Ch...

journal_title：Clinical and experimental immunology

authors： Greenspan JS,Gadol N,Olson JA,Talal N

更新日期：1981-06-01 00:00:00

abstract：:The possibility that shared idiotypes may be present on antibodies of different specificities was explored using sera from 13 patients with systemic lupus erythematosus. Eleven sera had anti-DNA and seven carried the 16/6 idiotype (ID). Two of the sera with 16/6 ID also had lymphocytotoxic antibodies, the activity of ...

journal_title：Clinical and experimental immunology

authors： Lydyard PM,Isenberg D,de Sousa B,Mackenzie L,Cooke A

更新日期：1987-03-01 00:00:00

abstract：:Dendritic cells were enriched from adenoids of children with otitis media with effusion (OME) by density gradient centrifugation and culture techniques. An enrichment of 40-140-fold was obtained for dendritic cells. These cells were identified using morphology, enzyme cytochemistry, immunocytochemistry and functional ...

journal_title：Clinical and experimental immunology

authors： van Nieuwkerk EB,van der Baan S,Richters CD,Kamperdijk EW

更新日期：1992-05-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disease primarily affecting cartilaginous joints but also extra-articular tissues such as the nose and upper respiratory tract. We have investigated extra-articular cartilage involvement in two commonly used animal models for RA, collagen-induced and pristane-induced...

journal_title：Clinical and experimental immunology

authors： Hansson AS,Lu S,Holmdahl R

更新日期：2002-01-01 00:00:00

abstract：:Cutaneous T-cell lymphoma (CTCL) is a clonally derived, skin invasive malignancy of CD4+ cells with the phenotype of mature helper T cells. We previously demonstrated that the leukaemic form of CTCL (Sézary), is characterized by prominent immunological defects including depressed cell-mediated immunity. We also demons...

journal_title：Clinical and experimental immunology

authors： Rook AH,Gottlieb SL,Wolfe JT,Vowels BR,Sood SS,Niu Z,Lessin SR,Fox FE

更新日期：1997-01-01 00:00:00

abstract：:The proinflammatory cytokines play a central role in mediating cellular and physiological responses, and levels may reflect immune system effectiveness. In this study, the effect of ageing on the inflammatory response was examined using a novel method to detect production of the proinflammatory cytokines, i.e. tumour ...

journal_title：Clinical and experimental immunology

authors： O'Mahony L,Holland J,Jackson J,Feighery C,Hennessy TP,Mealy K

更新日期：1998-08-01 00:00:00

abstract：:We report here the characterization and fine specificity of a human monoclonal IgM lambda reacting with double stranded DNA. The purified IgM and its Fab fragment bind to DNA in the Farr or Crithidia lucilae assays as well as in an immunoenzymatic test. In the latter case, binding was inhibited by native DNA, by DNA a...

journal_title：Clinical and experimental immunology

authors： Fermand JP,Danon F,Brouet JC

更新日期：1985-02-01 00:00:00

abstract：:In a study of 75 alveolar cell co-cultures from 55 HIV-seropositive subjects, p24 antigen production was identified by ELISA in 11 out of 26 (42%) of unseparated cell cultures, 15 out of 39 (38%) purified alveolar macrophage cultures and eight out of 10 purified alveolar lymphocyte samples. Positivity in unseparated c...

journal_title：Clinical and experimental immunology

authors： Jeffrey AA,Israël-Biet D,Andrieu JM,Even P,Venet A

更新日期：1991-06-01 00:00:00

abstract：:In fifty-seven healthy individuals a significant correlation ( r = 0.3, P < 0.05) has been found between responses of their lymphocytes to stimulation by PHA and by pooled lymphocytes in MLC. It is suggested that these tests quantitate the general status of T cell reactivity of individuals, and may be used in conjunct...

journal_title：Clinical and experimental immunology

authors： Nanra SK,Boettcher B

更新日期：1980-07-01 00:00:00

abstract：:One hundred and sixty-two unrelated, healthy normals and 118 unrelated SLE patients were subdivided by sex, race, and disease, and each group was in Hardy-Weinberg equilibrium for autosomal codominant expression of the four CR1 alleles. There were no significant phenotypic differences between males and females (P grea...

journal_title：Clinical and experimental immunology

authors： Van Dyne S,Holers VM,Lublin DM,Atkinson JP

更新日期：1987-06-01 00:00:00

abstract：:Idiopathic histaminergic acquired angioedema (IH-AAE) is a common cause of recurrent angioedema without wheals. It is a mast cell-mediated disease thought to belong to the same clinical entity as chronic urticaria (CU). The objective of this study was to describe the clinical and epidemiological characteristics of IH-...

journal_title：Clinical and experimental immunology

authors： Faisant C,Boccon-Gibod I,Mansard C,Dumestre Perard C,Pralong P,Chatain C,Deroux A,Bouillet L

更新日期：2016-07-01 00:00:00