当前位置： SCI文献检索 > SCHIZOPHRENIA RESEARCH期刊下所有文献 > The efficacy of supported employment for middle-aged and older people with schizophrenia.

The efficacy of supported employment for middle-aged and older people with schizophrenia.

Abstract：

OBJECTIVE:Supported employment is the evidence-based treatment of choice for assisting individuals with severe mental illness to achieve competitive employment, but few supported employment programs specifically target older clients with psychiatric illness. The purpose of this study was to evaluate the efficacy of supported employment for middle-aged or older people with schizophrenia. METHOD:Participants included 58 outpatients with schizophrenia or schizoaffective disorder aged 45 or older who were recruited from a community mental health clinic. Participants were randomly assigned to receive Individual Placement and Support (IPS; the manualized version of supported employment) or conventional vocational rehabilitation (CVR) for one year, and completed assessments at baseline, six months, and twelve months. RESULTS:IPS was superior to CVR on nearly all work outcome measures, including attainment of competitive employment, weeks worked, and wages earned. Fifty-seven percent of IPS participants worked competitively, compared with 29% of CVR participants; 70% of IPS participants obtained any paid work, compared with 36% of CVR participants. Within the IPS group, better baseline functional capacity (as measured by the UCSD Performance Based Skills Assessment) and more recent employment were modestly associated with better work outcomes. CONCLUSIONS:Middle-aged and older adults with schizophrenia are good candidates for supported employment services.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Twamley EW,Vella L,Burton CZ,Becker DR,Bell MD,Jeste DV

doi

10.1016/j.schres.2011.11.036

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

100-4

issue

1-3

eissn

0920-9964

issn

1573-2509

pii

S0920-9964(11)00634-7

journal_volume

135

pub_type

杂志文章,随机对照试验

相关文献

SCHIZOPHRENIA RESEARCH文献大全
  • Social-cognitive brain function and connectivity during visual perspective-taking in autism and schizophrenia.

    abstract：BACKGROUND:Autism spectrum disorder (ASD) and schizophrenia are neurodevelopmental conditions that are characterized by significant social impairment. Emerging genomic and neurobiological evidence has increasingly pointed to shared pathophysiologic mechanisms in the two disorders. Overlap in social impairment may refle...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.03.009

    authors： Eack SM,Wojtalik JA,Keshavan MS,Minshew NJ

    更新日期：2017-05-01 00:00:00

  • The impact of developmental instability on Voxel-Based Morphometry analyses of neuroanatomical abnormalities in schizophrenia.

    abstract：:The etiologic factors underlying schizophrenia have been conceptualized as reflecting two largely genetic components - those unique to schizophrenia and those representing vulnerability to neurodevelopmental deviation in general. The Developmental Instability (DI) approach suggests that the latter can be indexed by mi...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2009.08.014

    authors： Euler M,Thoma RJ,Gangestad SW,Cañive JM,Yeo RA

    更新日期：2009-11-01 00:00:00

  • Illness versus substance use effects on the frontal white matter in early phase schizophrenia: A 4Tesla (1)H-MRS study.

    abstract：OBJECTIVE:Young adults with early phase schizophrenia often report a past or current pattern of illicit substance use and/or alcohol misuse. Still, little is known about the cumulative and separate effects of each stressor on white matter tissue, at this vulnerable period of brain development. METHODS:Participants inv...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.04.022

    authors： Bernier D,Bartha R,McAllindon D,Hanstock CC,Marchand Y,Dillen KNH,Gallant M,Good KP,Tibbo PG

    更新日期：2016-08-01 00:00:00

  • Changing incidence of psychotic disorders among the young in Zurich.

    abstract：:There is controversy over whether the incidence rates of schizophrenia and psychotic disorders have changed in recent decades. To detect deviations from trends in incidence, we analysed admission data of patients with an ICD-8/9/10 diagnosis of psychotic disorders in the Canton Zurich / Switzerland, for the period 197...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2007.06.001

    authors： Ajdacic-Gross V,Lauber C,Warnke I,Haker H,Murray RM,Rössler W

    更新日期：2007-09-01 00:00:00

  • Automatic affective processing impairments in patients with deficit syndrome schizophrenia.

    abstract：:Affective impairments were examined in patients with and without deficit syndrome schizophrenia. Two Emotional Stroop tasks designed to measure automatic processing of emotional information were administered to deficit (n=15) and non-deficit syndrome (n=26) schizophrenia patients classified according to the Schedule f...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2008.01.014

    authors： Strauss GP,Allen DN,Duke LA,Ross SA,Schwartz J

    更新日期：2008-07-01 00:00:00

  • Diagnostic stability over one year in first-episode psychosis.

    abstract：:Results of first-episode psychosis studies have shown that the diagnosis of schizophrenia is more stable across time than other diagnoses within the psychosis spectrum disorders. The objective of this study was to determine the diagnostic stability in a sample of first-episode patients and to determine the factors tha...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2006.04.018

    authors： Addington J,Chaves A,Addington D

    更新日期：2006-09-01 00:00:00

  • Cognitive remediation therapy (CRT) for young early onset patients with schizophrenia: an exploratory randomized controlled trial.

    abstract：BACKGROUND:Schizophrenia with an onset in adolescence is known to be associated with a poorer outcome and cognitive difficulties. These impairments have an impact on quality of life and represent treatment targets. Cognitive remediation therapy (CRT) attempts to improve cognitive deficits by teaching information proces...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2007.03.030

    authors： Wykes T,Newton E,Landau S,Rice C,Thompson N,Frangou S

    更新日期：2007-08-01 00:00:00

  • Weight gain with clozapine: 8-year cohort naturalistic study among hospitalized Chinese schizophrenia patients.

    abstract：OBJECTIVE:Clozapine is associated with significant weight gain. However, it is still debatable whether the majority of weight gain occurs in the early phase of treatment or if weight gain is a persistent side effect. The inconsistent results in previous outpatient studies may be due to many confounding factors, such as...

    journal_title：Schizophrenia research

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.schres.2008.10.023

    authors： Bai YM,Chen JY,Chen TT,Lin CY,Chou P,Su TP,Lin CC

    更新日期：2009-03-01 00:00:00

  • Late electrophysiological potentials and emotion in schizophrenia: A meta-analytic review.

    abstract：INTRODUCTION:There is mixed evidence about emotional processing abnormalities in schizophrenia and schizoaffective disorder, with self-reports and clinician ratings indicating significant differences between patients and controls, but studies of in-the-moment, self-reported emotional experience finding only small diffe...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.schres.2019.07.013

    authors： Castro MK,Bailey DH,Zinger JF,Martin EA

    更新日期：2019-09-01 00:00:00

  • BDNF Val66Met and spontaneous dyskinesias in non-clinical psychosis.

    abstract：BACKGROUND:Evidence indicating that symptoms of non-clinical psychosis (NCP) occur in 6-8% of the general population suggests that psychosis may occur across a continuum. Although a number of studies have examined environmental contributors, to date there have been few investigations of biological/genetic factors in th...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.06.018

    authors： Mittal VA,Smolen A,Dean DJ,Pelletier AL,Lunsford-Avery J,Smith A

    更新日期：2012-09-01 00:00:00

  • Lowered paraoxonase 1 (PON1) activity is associated with increased cytokine levels in drug naïve first episode psychosis.

    abstract：BACKGROUND:Activated immune-inflammatory pathways play an important role in the pathophysiology of schizophrenia. Paraoxonase 1 (PON1) activity is inversely associated with inflammatory responses in numerous clinical conditions. The aims of this study were to delineate serum arylesterase PON1 activity in drug-naïve fir...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.06.009

    authors： Brinholi FF,Noto C,Maes M,Bonifácio KL,Brietzke E,Ota VK,Gadelha A,Cordeiro Q,Belangero SI,Bressan RA,Vargas HO,Higachi L,de Farias CC,Moreira EG,Barbosa DS

    更新日期：2015-08-01 00:00:00

  • Impaired cognitive control mediates the relationship between cortical thickness of the superior frontal gyrus and role functioning in schizophrenia.

    abstract：:Structural abnormalities in the lateral prefrontal cortex (LPFC) are well-documented in schizophrenia and recent evidence suggests that these abnormalities relate to functional outcome. Cognitive control mechanisms, reliant on the LPFC, are impaired in schizophrenia and predict functional outcome, thus impaired cognit...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2013.12.005

    authors： Tully LM,Lincoln SH,Liyanage-Don N,Hooker CI

    更新日期：2014-02-01 00:00:00

  • An assessment of the Wisconsin Card Sorting Test as an indicator of liability to schizophrenia.

    abstract：:In order to test the hypothesis that a poor performance in the Wisconsin test (WCST) may be an indicator of liability to schizophrenia, we compared the WCST performances of patients with DSM III-R schizophrenia, normal controls, and patients with schizotypal personality disorder (SZT PD). While schizophrenic patients ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/0920-9964(94)90007-8

    authors： Battaglia M,Abbruzzese M,Ferri S,Scarone S,Bellodi L,Smeraldi E

    更新日期：1994-12-01 00:00:00

  • Psychological well-being and mental health recovery in the NIMH RAISE early treatment program.

    abstract：:Recovery-oriented practices that promote client-centered care, collaboration, and functional outcome have been recommended to improve treatment engagement, especially for individuals with serious mental illness (SMI). Psychological well-being (PWB) is related to recovery and refers to experiencing purpose and meaning ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.11.032

    authors： Browne J,Penn DL,Meyer-Kalos PS,Mueser KT,Estroff SE,Brunette MF,Correll CU,Robinson J,Rosenheck RA,Schooler N,Robinson DG,Addington J,Marcy P,Kane JM

    更新日期：2017-07-01 00:00:00

  • No evidence for association of the dysbindin gene [DTNBP1] with schizophrenia in an Irish population-based study.

    abstract：:A recent family-based association study identified a putative association between variants in the dystrobrevin binding protein 1 (dysbindin) gene (DTNBP1) and schizophrenia. This study used a sample of 270 Irish pedigrees multiply affected with schizophrenia. We attempted to replicate these findings in an independent ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(02)00527-3

    authors： Morris DW,McGhee KA,Schwaiger S,Scully P,Quinn J,Meagher D,Waddington JL,Gill M,Corvin AP

    更新日期：2003-04-01 00:00:00

  • Association of maternal exposure to terror attacks during pregnancy and the risk of schizophrenia in the offspring: A population-based study.

    abstract：:This study tested the hypothesis that maternal exposure to terror attacks during pregnancy is associated with the risk of schizophrenia in the offspring. A population-based study was conducted of Israeli children born between 1975 and 1995 and that were registered in the Ministry of Interior and followed up in the Min...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2018.04.024

    authors： Weinstein Y,Levav I,Gelkopf M,Roe D,Yoffe R,Pugachova I,Levine SZ

    更新日期：2018-09-01 00:00:00

  • Neither protein kinase C nor adenylate cyclase are altered in the striatum from subjects with schizophrenia.

    abstract：:Dopamine (DA) D2 receptors which act by modulating second messenger pathways that include protein kinase C (PKC) and adenylate cyclase (AC) have been repeatedly shown to be increased in striatum from subjects with schizophrenia. Therefore it seemed possible that chronic up-regulation of DA-D2 receptors in the schizoph...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(96)00065-5

    authors： Opeskin K,Dean B,Pavey G,Hill C,Keks N,Copolov D

    更新日期：1996-11-15 00:00:00

  • Symptomatic remission and associated factors in a catchment area based population of older patients with schizophrenia.

    abstract：BACKGROUND:Symptomatic remission and its associated factors have been evaluated in several studies of younger schizophrenic patients. Although the number of older individuals with schizophrenia is rapidly growing, evaluations of remission in elderly patients are scarce and limited to samples of convenience, questioning...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2010.09.003

    authors： Meesters PD,Comijs HC,de Haan L,Smit JH,Eikelenboom P,Beekman AT,Stek ML

    更新日期：2011-03-01 00:00:00

  • A potential role for adjunctive omega-3 polyunsaturated fatty acids for depression and anxiety symptoms in recent onset psychosis: Results from a 16 week randomized placebo-controlled trial for participants concurrently treated with risperidone.

    abstract：:Omega-3 treatment studies for multi-episode schizophrenia or clinical high risk for conversion to psychosis states have had variable, and often negative, results. To examine adjunctive omega-3 treatment for recent onset psychosis, participants aged 15-40 years with recent onset schizophrenia-spectrum (n = 46) or bipol...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2018.09.006

    authors： Robinson DG,Gallego JA,John M,Hanna LA,Zhang JP,Birnbaum ML,Greenberg J,Naraine M,Peters BD,McNamara RK,Malhotra AK,Szeszko PR

    更新日期：2019-02-01 00:00:00

  • Adolescent developmental change in topography of EEG amplitude.

    abstract：:EEGs were recorded from 32 channels in 30 normal males, ages 16-22. Delta activity decreased throughout this age range. This decrease was greatest in the left frontal and temporal regions; no occipital lead showed this pattern. Relative EEG amplitude analysis, based on normalized maps, revealed decreases with age acro...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/0920-9964(92)90039-8

    authors： Buchsbaum MS,Mansour CS,Teng DG,Zia AD,Siegel BV Jr,Rice DM

    更新日期：1992-07-01 00:00:00

  • Candidate metabolic biomarkers for schizophrenia in CNS and periphery: Do any possible associations exist?

    abstract：:Due to the limitations of analytical techniques and the complicity of schizophrenia, nowadays it is still a challenge to diagnose and stratify schizophrenia patients accurately. Many attempts have been made to identify and validate available biomarkers for schizophrenia from CSF and/or peripheral blood in clinical stu...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2019.03.009

    authors： Cao T,Li N,Cai H

    更新日期：2020-12-01 00:00:00

  • Longitudinal changes in hippocampal volume in the Edinburgh High Risk Study of Schizophrenia.

    abstract：:Schizophrenia is associated with structural brain abnormalities that are likely to be present before disease onset. It remains unclear to what extent these represent general vulnerability indicators or are associated with the developing clinical state itself. It also remains unclear whether such state or trait alterat...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2014.12.003

    authors： Bois C,Levita L,Ripp I,Owens DCG,Johnstone EC,Whalley HC,Lawrie SM

    更新日期：2016-06-01 00:00:00

  • A multicenter, randomized, double-blind, controlled phase 3 trial of fixed-dose brexpiprazole for the treatment of adults with acute schizophrenia.

    abstract：:The objective of this study was to evaluate the efficacy, safety and tolerability of brexpiprazole versus placebo in adults with acute schizophrenia. This was a 6-week, multicenter, placebo-controlled double-blind phase 3 study. Patients with acute schizophrenia were randomized to brexpiprazole 1, 2 or 4 mg, or placeb...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.schres.2015.01.038

    authors： Kane JM,Skuban A,Ouyang J,Hobart M,Pfister S,McQuade RD,Nyilas M,Carson WH,Sanchez R,Eriksson H

    更新日期：2015-05-01 00:00:00

  • The contribution of the contingent negative variation (CNV) to goal maintenance.

    abstract：:The dot pattern expectancy (DPX) task has been strongly recommended as a measure of goal maintenance, which is impaired in schizophrenia patients. The current event-related potential (ERP) study was designed mainly to identify the ERP component that could represent the goal maintenance process of the DPX task as index...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.09.038

    authors： Shen A,Zhao W,Han B,Zhang Q,Zhang Z,Chen X,Zhai J,Chen M,Du B,Deng X,Ji F,Wang C,Xiang YT,Wu H,Dong Q,Chen C,Li J

    更新日期：2018-05-01 00:00:00

  • Association of tumor necrosis factor alpha gene -G308A polymorphism with schizophrenia.

    abstract：BACKGROUND:Tumor necrosis factor alpha (TNFalpha), a cytokine involved in inflammatory processes, has been implicated in the pathophysiology of schizophrenia. The chromosomal location in the major histocompatibility complex (MHC) region on 6p21.1-21.3, a region with evidence for linkage, suggests a role in susceptibili...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(02)00534-0

    authors： Schwab SG,Mondabon S,Knapp M,Albus M,Hallmayer J,Borrmann-Hassenbach M,Trixler M,Gross M,Schulze TG,Rietschel M,Lerer B,Maier W,Wildenauer DB

    更新日期：2003-12-01 00:00:00

  • Overview of short- and long-term tolerability and safety of brexpiprazole in patients with schizophrenia.

    abstract：:Second-generation antipsychotics have demonstrated efficacy for patients with schizophrenia but are associated with wide-ranging side effects. Brexpiprazole, a serotonin-dopamine activity modulator, has demonstrated efficacy in adult patients with schizophrenia. This paper provides an overview of the safety and tolera...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.schres.2016.04.013

    authors： Kane JM,Skuban A,Hobart M,Ouyang J,Weiller E,Weiss C,Correll CU

    更新日期：2016-07-01 00:00:00

  • Comparison of cost, dosage and clinical preference for risperidone and olanzapine.

    abstract：BACKGROUND:Because risperidone and olanzapine have similar efficacy and tolerability in the treatment of schizophrenia, costs, physician experience, and preference become relevant considerations in making treatment decisions. The purpose of this paper is to compare daily treatment costs of risperidone and olanzapine, a...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(00)00036-0

    authors： Rabinowitz J,Lichtenberg P,Kaplan Z

    更新日期：2000-12-15 00:00:00

  • Smaller superior temporal gyrus volume specificity in schizotypal personality disorder.

    abstract：BACKGROUND:Superior temporal gyrus (STG/BA22) volume is reduced in schizophrenia and to a milder degree in schizotypal personality disorder (SPD), representing a less severe disorder in the schizophrenia spectrum. SPD and Borderline personality disorder (BPD) are severe personality disorders characterized by social and...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2009.04.027

    authors： Goldstein KE,Hazlett EA,New AS,Haznedar MM,Newmark RE,Zelmanova Y,Passarelli V,Weinstein SR,Canfield EL,Meyerson DA,Tang CY,Buchsbaum MS,Siever LJ

    更新日期：2009-07-01 00:00:00

  • Differential relationship between neurological and cognitive dysfunction in first episode psychosis patients and in healthy individuals.

    abstract：:The minor neurological and cognitive deficits consistently reported in psychoses may reflect the same underlying brain dysfunction. Still, even in healthy individuals minor neurological abnormalities are associated with worse cognitive function. Therefore, establishing which neurological and cognitive deficits are spe...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.09.016

    authors： Mellacqua Z,Eyeson J,Orr KD,Morgan KD,Zanelli J,Lloyd T,Morgan C,Fearon P,Hutchinson G,Doody GA,Chan RC,Harrison G,Jones PB,Murray RM,Reichenberg A,Dazzan P

    更新日期：2012-12-01 00:00:00

  • Clinical, cognitive and functional characteristics of long-stay patients with schizophrenia: a comparison of VA and state hospital patients.

    abstract：:Long-stay patients constitute a small proportion of all patients with schizophrenia, but in both VA and state psychiatric systems these patients account for a majority of the costs associated with treatment of the illness. VA and state patients would be expected to differ in several respects, including age at onset an...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(99)00182-6

    authors： Harvey PD,Jacobsen H,Mancini D,Parrella M,White L,Haroutunian V,Davis KL

    更新日期：2000-05-25 00:00:00