Adolescent developmental change in topography of EEG amplitude.

abstract：:The influence of neurocognition, including general intelligence, on theory of mind (ToM) among patients with schizophrenia spectrum disorder is controversial. The purpose of the present study was to identify the influences of the non-ToM cognition and general intelligence on ToM performance in individuals at ultra-hig...

journal_title：Schizophrenia research

authors： Hur JW,Byun MS,Shin NY,Shin YS,Kim SN,Jang JH,Kwon JS

更新日期：2013-09-01 00:00:00

abstract：:Arinami et al. (1994) reported an association between the Ser311/Cys311 variant of the DRD2 gene and schizophrenia in a Japanese population. We did not find statistically significant differences in the distribution of the allele frequencies between schizophrenics (103) and controls (97) in a case-control sample (chi 2...

journal_title：Schizophrenia research

authors： Verga M,Macciardi F,Pedrini S,Cohen S,Smeraldi E

更新日期：1997-05-24 00:00:00

abstract：BACKGROUND:We previously developed a novel method of identifying children aged 9-12 years who may be at elevated risk of developing schizophrenia and the spectrum disorders because they present a triad of putative antecedents of schizophrenia (ASz). The present study aimed to determine whether ASz children also present...

journal_title：Schizophrenia research

authors： Cullen AE,Dickson H,West SA,Morris RG,Mould GL,Hodgins S,Murray RM,Laurens KR

更新日期：2010-08-01 00:00:00

abstract：:Long-stay patients constitute a small proportion of all patients with schizophrenia, but in both VA and state psychiatric systems these patients account for a majority of the costs associated with treatment of the illness. VA and state patients would be expected to differ in several respects, including age at onset an...

journal_title：Schizophrenia research

authors： Harvey PD,Jacobsen H,Mancini D,Parrella M,White L,Haroutunian V,Davis KL

更新日期：2000-05-25 00:00:00

abstract：BACKGROUND:The InterSePT Scale for Suicidal Thinking (ISST) is a 12-item instrument for the assessment of current suicidal ideation in patients with schizophrenia and schizoaffective disorders. We report the psychometric characteristics of this new scale based on two studies. METHOD:In Study 1, 22 inpatients with schi...

journal_title：Schizophrenia research

authors： Lindenmayer JP,Czobor P,Alphs L,Nathan AM,Anand R,Islam Z,Chou JC,InterSePT Study Group.

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Although altered gamma-aminobutyric acid (GABA) neurotransmission has been implicated in the pathophysiology of schizophrenia, it is unclear whether the influence of GABA on working memory processes is confounded by nicotine use in this population. It is therefore crucial to evaluate working memory and its u...

journal_title：Schizophrenia research

authors： Bridgman AC,Barr MS,Goodman MS,Chen R,Rajji TK,Daskalakis ZJ,George TP

更新日期：2016-03-01 00:00:00

abstract：:We have previously reported aberrations in the striatal presynaptic dopamine function in neuroleptic-naive schizophrenic patients compared to healthy controls (Hietala, J., Syvälahti, E., Vuorio, K. et al., 1995. Lancet 346, 1130-1131). In this extended study we explore whether the altered presynaptic dopamine functio...

journal_title：Schizophrenia research

authors： Hietala J,Syvälahti E,Vilkman H,Vuorio K,Räkköläinen V,Bergman J,Haaparanta M,Solin O,Kuoppamäki M,Eronen E,Ruotsalainen U,Salokangas RK

更新日期：1999-01-04 00:00:00

abstract：BACKGROUND:There is increased interest in the impact of new long-acting treatments on health-related quality of life (HRQoL) in patients with schizophrenia. The aim of this study was to evaluate the impact of treatment with subcutaneous injections of RBP-7000, a new sustained-release formulation of risperidone, compare...

journal_title：Schizophrenia research

authors： Isitt JJ,Nadipelli VR,Kouassi A,Fava M,Heidbreder C

更新日期：2016-07-01 00:00:00

abstract：:Patients with schizophrenia and bipolar disorder (BD) shared a significant overlap in genetic susceptibility, pharmacological treatment responses, neuropsychological deficits, and epidemiological features. However, it remains unknown whether these clinical overlaps are mediated by shared or disorder-specific abnormali...

journal_title：Schizophrenia research

authors： Dong D,Wang Y,Chang X,Jiang Y,Klugah-Brown B,Luo C,Yao D

更新日期：2017-07-01 00:00:00

abstract：:The distribution of schizophrenia in families supports the hypothesis of heritable risk factors in schizophrenia, but there is as yet no identification of an inherited neurobiological defect. Human embryonic brain tissue fragments, derived from first trimester abortions, can be transplanted into rat hosts, where they ...

journal_title：Schizophrenia research

authors： Freedman R,Strömberg I,Nordström AL,Seiger A,Olson L,Bygdeman M,Wiesel FA,Granholm AC,Hoffer BJ

更新日期：1994-10-01 00:00:00

abstract：:In a 12-week randomized open-label trial, adults diagnosed with schizophrenia experiencing inadequate efficacy and/or poor tolerability on risperidone, olanzapine, or aripiprazole were randomized to switch to iloperidone either gradually (ie, down-titration of current therapy over the first 2weeks [to 50% on Day 1, 25...

journal_title：Schizophrenia research

authors： Weiden PJ,Citrome L,Alva G,Brams M,Glick ID,Jackson R,Mattingly G,Kianifard F,Meng X,Pestreich L,Hochfeld M,Winseck A

更新日期：2014-03-01 00:00:00

abstract：:Elevated serum levels of Interleukin-3 (IL-3), a major component of the cytokines, have been observed in chronic and medicated patients with schizophrenia, but this elevation may reflect either or both medication and illness chronicity effects. Thus, we compared serum IL-3 levels in first-episode drug-naive (FEDN) to ...

journal_title：Schizophrenia research

authors： Fu YY,Zhang T,Xiu MH,Tang W,Han M,Yun LT,Chen DC,Chen S,Tan SP,Soares JC,Tang WJ,Zhang XY

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Alterations in the inhibitory circuitry of the dorsolateral prefrontal cortex (DLPFC) in schizophrenia include reduced expression of the messenger RNA (mRNA) for somatostatin (SST), a neuropeptide present in a subpopulation of gamma-aminobutyric acid (GABA) neurons. Neuropeptide Y (NPY) is expressed in a sub...

journal_title：Schizophrenia research

authors： Morris HM,Stopczynski RE,Lewis DA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:In schizophrenic psychoses, the normal sexual dimorphism of the brain has been shown to be disrupted or even reversed. Little is known, however, at what time point in emerging psychosis this occurs. We have therefore examined, if these alterations are already present in the at-risk mental state (ARMS) for ps...

journal_title：Schizophrenia research

authors： Egloff L,Lenz C,Studerus E,Harrisberger F,Smieskova R,Schmidt A,Huber C,Simon A,Lang UE,Riecher-Rössler A,Borgwardt S

更新日期：2018-09-01 00:00:00

abstract：:Recently, apolipoprotein D (apoD), a protein that is involved in the essential polyunsaturated fatty acid (EPUFA) transport and metabolism, and neuronal growth and regeneration was reported to have increased in the postmortem brain and decreased in the serum of schizophrenia patients. We studied the plasma apoD levels...

journal_title：Schizophrenia research

authors： Mahadik SP,Khan MM,Evans DR,Parikh VV

更新日期：2002-11-01 00:00:00

abstract：:The memory profile of acute and chronic schizophrenic patients was examined according to the information processing model, with which encoding, retention and retrieval processes of these patients were compared. The effects of an external organizational strategy on their verbal learning and memory were also examined. T...

journal_title：Schizophrenia research

authors： Chan AS,Kwok IC,Chiu H,Lam L,Pang A,Chow LY

更新日期：2000-02-14 00:00:00

abstract：:Two reaction time (RT) paradigms were used to study clozapine's effects on sustained and selective attention compared to fluphenazine and placebo in 25 chronic schizophrenic patients. Sensory dominance was studied via simple and choice RTs to lights and tones, and on double-stimulus trials in which the two stimuli wer...

journal_title：Schizophrenia research

authors： Zahn TP,Pickar D,Haier RJ

更新日期：1994-09-01 00:00:00

abstract：:This is the first study to investigate whether positive family history (FH) of psychosis and affective disorders moderates the relationship between child diagnostic status and parent-reported social and behavioral problems on the Child Behavior Checklist (CBCL) in clinical high-risk adolescents. This longitudinal inve...

journal_title：Schizophrenia research

authors： Simeonova DI,Lee FJ,Walker EF

更新日期：2015-08-01 00:00:00

abstract：:Phencyclidine (PCP), ketamine and other N-methyl-D-aspartate (NMDA) antagonists induce schizophrenia-like symptoms in normal volunteers, suggesting that endogenous dysfunction or dysregulation of NMDA receptors may contribute to the pathophysiology of schizophrenia. Glycine and D-cycloserine are potential treatments f...

journal_title：Schizophrenia research

authors： Heresco-Levy U,Javitt DC

更新日期：2004-02-01 00:00:00

abstract：:Recent molecular genetic studies have demonstrated X-chromosome abnormalities in the transmission of psychosis, a finding that may contribute to understanding sex differences in the disorder. Using our family high risk paradigm, we tested the hypothesis that there are sex-specific patterns of transmission of psychosis...

journal_title：Schizophrenia research

authors： Goldstein JM,Cherkerzian S,Seidman LJ,Petryshen TL,Fitzmaurice G,Tsuang MT,Buka SL

更新日期：2011-05-01 00:00:00

abstract：:There is strong evidence that hippocampal 5-hydroxytryptamine (5-HT) systems are affected in schizophrenia and hence we have studied a number of markers of the 5-HT system in hippocampi from subjects with schizophrenia. Using in situ radioligand binding with autoradiography we measured [(3)H]proplyamino-8-hydroxy-1,2,...

journal_title：Schizophrenia research

authors： Scarr E,Pavey G,Copolov D,Dean B

更新日期：2004-12-01 00:00:00

abstract：:Abnormalities of cerebellar structure and function, long recognized as a hallmark of chronic alcohol abuse, have also occasionally been noted in patients with schizophrenia. We used a four-point rating scale to assess clinical signs of cerebellar dysfunction in men meeting DSM-IV criteria for schizophrenia (N=34) and ...

journal_title：Schizophrenia research

authors： Deshmukh A,Rosenbloom MJ,Pfefferbaum A,Sullivan EV

更新日期：2002-10-01 00:00:00

abstract：INTRODUCTION:Progressive atrophy occurs in brain regions involved in the working memory network along the schizophrenia's course, but without parallel evolution of working memory impairment. We investigated the functional organization inside this network at different stages of the disease. METHODS:Twenty-eight patient...

journal_title：Schizophrenia research

authors： Faget-Agius C,Boyer L,Lançon C,Richieri R,Fassio E,Soulier E,Chanoine V,Auquier P,Ranjeva JP,Guye M

更新日期：2013-12-01 00:00:00

abstract：:Accumulating evidence showed that interleukin-2 (IL-2) may be involved in the pathophysiology of schizophrenia. Increased IL-2 levels have been found in the serum of schizophrenia patients with mixed results. In the present study, we assessed serum IL-2 levels in a large group of 160 schizophrenia patients compared to...

journal_title：Schizophrenia research

authors： Tan Y,Li Y,Tan S,Wang Z,Yang FD,Cao B,Zunta-Soares GB,Soares JC,Zhang XY

更新日期：2015-12-01 00:00:00

abstract：:Twenty-five schizophrenic patients diagnosed by DSM-III-R underwent event-related potentials and magnetic resonance imaging scans. Latency and amplitude of P300 waveform were measured using an auditory odd-ball paradigm. Anterior and posterior volumes of the superior temporal gyrus and medial temporal structure were m...

journal_title：Schizophrenia research

authors： Kawasaki Y,Maeda Y,Higashima M,Nagasawa T,Koshino Y,Suzuki M,Ide Y

更新日期：1997-08-29 00:00:00

abstract：AIM:To compare the prevalence and trends of antipsychotic drug use during pregnancy between countries across four continents. METHODS:Individually linked health data in Denmark (2000-2012), Finland (2005-2014), Iceland (2004-2017), Norway (2005-2015), Sweden (2006-2015), Germany (2006-2015), Australia (New South Wales...

journal_title：Schizophrenia research

authors： Reutfors J,Cesta CE,Cohen JM,Bateman BT,Brauer R,Einarsdóttir K,Engeland A,Furu K,Gissler M,Havard A,Hernandez-Diaz S,Huybrechts KF,Karlstad Ø,Leinonen MK,Li J,Man KKC,Pazzagli L,Schaffer A,Schink T,Wang Z,Yu Y,

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:Widespread white matter abnormalities and alterations in glutamate levels have been reported in patients with schizophrenia. We hypothesized that alterations in white matter integrity and glutamate levels in individuals at clinical high risk (CHR) for psychosis are associated with the subsequent developmen...

journal_title：Schizophrenia research

authors： León-Ortiz P,Reyes-Madrigal F,Kochunov P,Gómez-Cruz G,Moncada-Habib T,Malacara M,Mora-Durán R,Rowland LM,de la Fuente-Sandoval C

更新日期：2020-06-25 00:00:00

abstract：OBJECTIVE:The onset of psychosis is thought to be preceded by neurodevelopmental changes in the brain. However, the timing of these changes has not been established. We investigated structural brain changes in a sample of young adolescents (12-18 years) at ultra high-risk for psychosis (UHR). METHODS:Structural MRI da...

journal_title：Schizophrenia research

authors： Ziermans TB,Durston S,Sprong M,Nederveen H,van Haren NE,Schnack HG,Lahuis BE,Schothorst PF,van Engeland H

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:A literature review was conducted to ascertain whether or not EEG spectral abnormalities are consistent enough to warrant additional effort towards developing them into a clinical diagnostic test for schizophrenia. METHODS:Fifty three papers met criteria for inclusion into the review and 15 were included in ...

journal_title：Schizophrenia research

authors： Boutros NN,Arfken C,Galderisi S,Warrick J,Pratt G,Iacono W

更新日期：2008-02-01 00:00:00

abstract：:A study of mortality for all patients with schizophrenia admitted to the University Hospital of North Norway during 1980-2006 was performed, with a special focus on gender differences and changes in mortality during a period of transition from hospital-based to community-based care. A total of 1111 patients with schiz...

journal_title：Schizophrenia research

authors： Høye A,Jacobsen BK,Hansen V

更新日期：2011-11-01 00:00:00