Depressive symptoms and presynaptic dopamine function in neuroleptic-naive schizophrenia.

abstract：:A recent single-site study (Fisher et al., 2009. Am J Psychiatry. 166 (7) 805-11) showed that repeated training with the Brain Fitness Program (BFP) improved performance on a battery of neuropsychological tasks. If replicated these data suggest an important non-pharmacological method for ameliorating cognitive impairm...

journal_title：Schizophrenia research

authors： Murthy NV,Mahncke H,Wexler BE,Maruff P,Inamdar A,Zucchetto M,Lund J,Shabbir S,Shergill S,Keshavan M,Kapur S,Laruelle M,Alexander R

更新日期：2012-08-01 00:00:00

abstract：:A disturbance of "minimal self," - of the immediate sense of mine-ness inherent in experience-is hypothesized to be the core disturbance in schizophrenia. Research with the Examination of Anomalous Self Experience (EASE) has demonstrated the selective aggregation of anomalous self-experiences in the schizophrenia spec...

journal_title：Schizophrenia research

authors： Madeira L,Pienkos E,Filipe T,Melo M,Queiroz G,Eira J,Costa C,Figueira ML,Sass L

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Recent years have witnessed growing interest in the role of the social environment in the development and outcomes of schizophrenia. We investigated whether neighborhood characteristics are associated with two important prognostic factors in early-course psychosis, age at onset of psychosis (AOP) and duration...

journal_title：Schizophrenia research

authors： Ku BS,Pauselli L,Manseau M,Compton MT

更新日期：2020-04-01 00:00:00

abstract：:Mismatch negativity (MMN) and P3a are auditory event-related potential (ERP) components that show robust deficits in schizophrenia (SZ) patients and exhibit qualities of endophenotypes, including substantial heritability, test-retest reliability, and trait-like stability. These measures also fulfill criteria for use a...

journal_title：Schizophrenia research

authors： Light GA,Swerdlow NR,Thomas ML,Calkins ME,Green MF,Greenwood TA,Gur RE,Gur RC,Lazzeroni LC,Nuechterlein KH,Pela M,Radant AD,Seidman LJ,Sharp RF,Siever LJ,Silverman JM,Sprock J,Stone WS,Sugar CA,Tsuang DW,Tsuang MT

更新日期：2015-04-01 00:00:00

abstract：:The performance of chronic schizophrenic probands (n=21), their first-degree schizotypal (22) and non-schizotypal (19) relatives, and normal controls (24), was measured in two associative learning paradigms, latent inhibition and the Kamin blocking effect. These paradigms assess the effects on learning of initial expo...

journal_title：Schizophrenia research

authors： Martins Serra A,Jones SH,Toone B,Gray JA

更新日期：2001-03-30 00:00:00

abstract：:Stigma can be a major stressor for individuals with schizophrenia and other mental illnesses. It is unclear, however, why some stigmatized individuals appraise stigma as more stressful, while others feel they can cope with the potential harm posed by public prejudice. We tested the hypothesis that the level of perceiv...

journal_title：Schizophrenia research

authors： Rüsch N,Corrigan PW,Wassel A,Michaels P,Olschewski M,Wilkniss S,Batia K

更新日期：2009-05-01 00:00:00

abstract：:This prospective study examined the effect of medication compliance and substance abuse on 4 year outcome in 99 patients following a relapse of schizophrenia. Univariate survival analysis revealed longer community tenure in patients if they were over the age of 35 years, not admitted 2 years prior to the index episode...

journal_title：Schizophrenia research

authors： Hunt GE,Bergen J,Bashir M

更新日期：2002-04-01 00:00:00

abstract：:Classifications of psychotic disorders are moving towards utilizing dimensional symptom domains as the preferred mechanism for describing psychotic symptomatology. The ICD-11 has proposed six symptom domains (Positive symptoms, Negative symptoms, Depressive symptoms, Manic symptoms, Psychomotor symptoms, and Cognitive...

journal_title：Schizophrenia research

authors： Keeley JW,Gaebel W,First MB,Peterson DL,Rebello T,Sharan P,Reed GM

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Recent empirical evidence [Maher, B.A., Manschreck, T.C., Linnert, J., Candela, S., 2005. Quantitative assessment of the frequency of normal associations in the utterances of schizophrenia patients and healthy controls. Schizophrenia Research 78, 219-224] shows that schizophrenia patients produce an elevated...

journal_title：Schizophrenia research

authors： Lenzenweger MF,Miller AB,Maher BA,Manschreck TC

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To identify the determinants of schizophrenia-specific HRQoL levels, five types of factors (i.e., sociodemographic, clinical, psychopathological, neurocognitive, and psychosocial factors) were simultaneously investigated in the same cross-sectional sample. METHODS:A total of 120 patients with a diagnosis of sc...

journal_title：Schizophrenia research

authors： Chou CY,Ma MC,Yang TT

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:International studies indicate that the median prevalence of psychotic experiences in children is 7%. It has been proposed that environmental stress during pregnancy may affect the neurodevelopment of the foetus and lead to a vulnerability in the child to later stressors and psychopathology. AIM:In this stu...

journal_title：Schizophrenia research

authors： Dorrington S,Zammit S,Asher L,Evans J,Heron J,Lewis G

更新日期：2014-01-01 00:00:00

abstract：:We found previously that a subgroup of schizophrenic patients who passed screening tests of attentional competence showed memory deficits on word memory tasks, but were comparable with controls on tone memory tasks. To better understand the nature of language-specific memory deficits in this subgroup of patients, the ...

journal_title：Schizophrenia research

authors： Wexler BE,Donegan N,Stevens AA,Jacob SA

更新日期：2002-01-15 00:00:00

abstract：:Genetic factors that modulate the immune response have been implicated as risk factors for schizophrenia and cognitive impairment. We assessed the correlation between cognitive functioning and the LTA Cys13Arg polymorphism in 351 individuals with schizophrenia, 122 with bipolar disorder, and 160 controls. There was a ...

journal_title：Schizophrenia research

authors： Dickerson F,Boronow J,Stallings C,Origoni A,Yolken R

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Startle inhibition by weak prepulses (PPI) is studied to understand the biology of information processing in schizophrenia patients and healthy comparison subjects (HCS). The Consortium on the Genetics of Schizophrenia (COGS) identified associations between PPI and single nucleotide polymorphisms in schizoph...

journal_title：Schizophrenia research

authors： Swerdlow NR,Light GA,Sprock J,Calkins ME,Green MF,Greenwood TA,Gur RE,Gur RC,Lazzeroni LC,Nuechterlein KH,Radant AD,Ray A,Seidman LJ,Siever LJ,Silverman JM,Stone WS,Sugar CA,Tsuang DW,Tsuang MT,Turetsky BI,Braff D

更新日期：2014-02-01 00:00:00

abstract：:Schizophrenia is associated with impairments in social interactions, and the conditions under which patients live and undergo treatment appear to have an important role in the course of the disease. However, the influences of care settings on the course of cognition remain controversial. The closure of psychiatric hos...

journal_title：Schizophrenia research

authors： Nemoto T,Niimura H,Ryu Y,Sakuma K,Mizuno M

更新日期：2014-05-01 00:00:00

abstract：:Up to 50-90% of persons with schizophrenia smoke cigarettes. Limited data and theories suggest persons with schizophrenia may smoke for different reasons than persons without schizophrenia, making smoking cessation interventions particularly challenging in this population. Although health consequences of smoking are w...

journal_title：Schizophrenia research

authors： Wehring HJ,Liu F,McMahon RP,Mackowick KM,Love RC,Dixon L,Kelly DL

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Many studies have identified urban-rural differences in the occurrence of schizophrenia. Though unknown, the underlying causes responsible for these differences have been hypothesized to include urban-rural differences in toxic exposures, diet, infections, stress, or an artifact due to selective migration. F...

journal_title：Schizophrenia research

authors： Pedersen CB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The intrusion of associations into the utterances of schizophrenic individuals typically disrupts the coherence of the patient's utterances. Recent theoretical formulations of these phenomena have emphasized the hyperactivity) of associational networks in such language disturbance (e.g., Maher, B.A. 2003 Sch...

journal_title：Schizophrenia research

authors： Maher BA,Manschreck TC,Linnet J,Candela S

更新日期：2005-10-15 00:00:00

abstract：:Recent transcriptomic, proteomic and metabolomics studies have highlighted an abnormal cerebral glucose and energy metabolism as one of the potential pathophysiological mechanisms of schizophrenia. This raises the possibility that a metabolically-based intervention might have therapeutic value in the management of sch...

journal_title：Schizophrenia research

authors： Kraeuter AK,van den Buuse M,Sarnyai Z

更新日期：2019-04-01 00:00:00

abstract：:Learning and memory impairments are present in schizophrenia (SZ) throughout the illness course and predict psychosocial function. Abnormalities in prefrontal and hippocampal function are thought to contribute to SZ deficits. The radial arm maze (RAM) is a test of spatial learning and memory in rodents that relies on ...

journal_title：Schizophrenia research

authors： Spieker EA,Astur RS,West JT,Griego JA,Rowland LM

更新日期：2012-03-01 00:00:00

abstract：:In order to test the hypothesis that a poor performance in the Wisconsin test (WCST) may be an indicator of liability to schizophrenia, we compared the WCST performances of patients with DSM III-R schizophrenia, normal controls, and patients with schizotypal personality disorder (SZT PD). While schizophrenic patients ...

journal_title：Schizophrenia research

authors： Battaglia M,Abbruzzese M,Ferri S,Scarone S,Bellodi L,Smeraldi E

更新日期：1994-12-01 00:00:00

abstract：:Widely used in industrialized countries, cannabis is a neuromodulator substance. The cannabinoid system is present at critical stages of retinal processing. We have recently shown a delay in bipolar and ganglion cell responses in regular cannabis users, as observed using flash (fERG) and pattern (PERG) electroretinogr...

journal_title：Schizophrenia research

authors： Schwitzer T,Henrion ML,Sarre D,Albuisson E,Angioi-Duprez K,Giersch A,Lalanne L,Schwan R,Laprevote V

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:In schizophrenic psychoses, the normal sexual dimorphism of the brain has been shown to be disrupted or even reversed. Little is known, however, at what time point in emerging psychosis this occurs. We have therefore examined, if these alterations are already present in the at-risk mental state (ARMS) for ps...

journal_title：Schizophrenia research

authors： Egloff L,Lenz C,Studerus E,Harrisberger F,Smieskova R,Schmidt A,Huber C,Simon A,Lang UE,Riecher-Rössler A,Borgwardt S

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Epidemiologic evidence as early as the 1930s has suggested urbanization is linked to schizophrenia, either by place of admission, place of upbringing, or, more recently, place of birth. In the past decade, obstetric complications have been implicated in the etiology of schizophrenia. METHODS:With appropriat...

journal_title：Schizophrenia research

authors： Eaton WW,Mortensen PB,Frydenberg M

更新日期：2000-06-16 00:00:00

abstract：:The aim of the study was to assess changes in cortical thickness related to the use of n-3 polyunsaturated fatty acids (PUFA) as add-on therapy in patients with first episode schizophrenia. A double-blind randomized controlled study was conducted using a 26-week intervention composed of concentrated fish oil containin...

journal_title：Schizophrenia research

authors： Pawełczyk T,Piątkowska-Janko E,Bogorodzki P,Gębski P,Grancow-Grabka M,Trafalska E,Żurner N,Pawełczyk A

更新日期：2018-05-01 00:00:00

abstract：:Previous studies (including genome-wide association study (GWAS) and candidate gene studies) have revealed the important roles of genetic risk factors in schizophrenia, and RELN has been identified as a risk gene for this illness. We recently found that the low-density lipoprotein receptor-related protein 8 (LRP8), a ...

journal_title：Schizophrenia research

authors： Xiao X,Yu H,Li J,Wang L,Li L,Chang H,Zhang D,Yue W,Li M

更新日期：2020-01-01 00:00:00

abstract：:Previous studies have indicated that schizophrenic patients have olfactory deficits. The question as to whether olfactory deficits are due to chronic effects of medication has not been addressed. This is the first paper to report that never-medicated schizophrenic patients also have olfactory deficits. Twenty four nor...

journal_title：Schizophrenia research

authors： Wu J,Buchsbaum MS,Moy K,Denlea N,Kesslak P,Tseng H,Plosnaj D,Hetu M,Potkin S,Bracha S

更新日期：1993-03-01 00:00:00

abstract：:Polydipsia and water intoxication (PWI) are relatively frequent among schizophrenic subjects, particularly in institutional settings and may lead to severe complications. However, little is known on their association with other characteristics of psychosis. Hence, we took advantage of a cohort of 114 subjects extensiv...

journal_title：Schizophrenia research

authors： Poirier S,Legris G,Tremblay P,Michea R,Viau-Guay L,Mérette C,Bouchard RH,Maziade M,Roy MA

更新日期：2010-05-01 00:00:00

abstract：:Cognitive adaptation training (CAT) is a home-based, manualized treatment that utilizes environmental supports to improve target behaviors and functional outcomes in persons with schizophrenia. Although clinical trials have shown CAT to be effective across functional, clinical, and treatment adherence domains, when th...

journal_title：Schizophrenia research

authors： Kidd SA,Herman Y,Barbic S,Ganguli R,George TP,Hassan S,McKenzie K,Maples N,Velligan D

更新日期：2014-06-01 00:00:00

abstract：:Diminished expression is a diagnostic feature of a range of schizophrenia-spectrum disorders/conditions and is often unresponsive to treatment, is present across premorbid, first episode and various clinical states, and is considered a poor prognostic indicator. Surprisingly, little is known about diminished expressio...

journal_title：Schizophrenia research

authors： Cohen AS,Morrison SC,Callaway DA

更新日期：2013-08-01 00:00:00