Abstract：
OBJECTIVE:A literature review was conducted to ascertain whether or not EEG spectral abnormalities are consistent enough to warrant additional effort towards developing them into a clinical diagnostic test for schizophrenia. METHODS:Fifty three papers met criteria for inclusion into the review and 15 were included in a meta-analysis of the degree of significance of EEG deviations as compared to healthy controls. Studies were classified based on a 4-step approach based on guidelines for evaluating the clinical usefulness of a diagnostic test. RESULTS:Our review and meta-analysis revealed that most of the abnormalities are replicated in the expected directions with the most consistent results related to the increased preponderance of slow rhythms in schizophrenia patients. This effect remained consistent in un-medicated patients. Only a small number of studies provided data on the sensitivity and specificity of the findings in differentiating among the psychiatric disorders that frequently appear on the same differential diagnostic list as schizophrenia (Step 3 studies). No multicenter studies using standardized assessment criteria were found (Step 4 studies). CONCLUSIONS:Additional Step 3 and Step 4 studies are needed to draw conclusions on the usefulness of EEG spectral abnormalities as a diagnostic test for schizophrenia.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Boutros NN,Arfken C,Galderisi S,Warrick J,Pratt G,Iacono Wdoi
10.1016/j.schres.2007.11.020subject
Has Abstractpub_date
2008-02-01 00:00:00pages
225-37issue
1-3eissn
0920-9964issn
1573-2509pii
S0920-9964(07)00532-4journal_volume
99pub_type
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journal_title：Schizophrenia research
pub_type： 杂志文章,评审
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journal_title：Schizophrenia research
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journal_title：Schizophrenia research
pub_type： 杂志文章
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pub_type： 杂志文章,随机对照试验
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更新日期：2014-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2005-09-15 00:00:00
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pub_type： 杂志文章,meta分析,评审
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doi：10.1016/j.schres.2012.10.003
更新日期：2012-12-01 00:00:00
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pub_type： 杂志文章,多中心研究
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doi：10.1016/j.schres.2020.06.032
更新日期：2020-09-01 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
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更新日期：2014-08-01 00:00:00
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journal_title：Schizophrenia research
pub_type： 杂志文章
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更新日期：2016-08-01 00:00:00
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pub_type： 杂志文章
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更新日期：2016-04-01 00:00:00
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journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2015.11.022
更新日期：2016-01-01 00:00:00
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journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2016.04.004
更新日期：2016-07-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.schres.2016.10.020
更新日期：2017-04-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.schres.2005.05.017
更新日期：2005-10-15 00:00:00
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journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2011.12.007
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVES:Gender differences in psychotic disorder have been observed in terms of illness onset and course; however, past research has been limited by inconsistencies between studies and the lack of epidemiological representative of samples assessed. Thus, the aim of this study was to elucidate gender differences in a...
journal_title：Schizophrenia research
pub_type： 杂志文章
doi：10.1016/j.schres.2009.07.002
更新日期：2009-10-01 00:00:00
