The economic cost of brain disorders in Europe.

abstract：:We present the baseline characteristics of 101 patients with normal pressure hydrocephalus (NPH), entering a study that evaluates the diagnostic reliability of CSF outflow resistance. Patients were assessed by a gait scale consisting of 10 features of walking and the number of steps and seconds necessary for 10 m, a d...

journal_title：European journal of neurology

authors： Boon AJ,Tans JT,Delwel EJ,Egeler-Peerdeman SM,Hanlo PW,Wurzer JA,Hermans J

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Observational study to evaluate long-term effects of deep brain stimulation (DBS) of the globus pallidus internus (GPi) and the ventral intermediate thalamic nucleus (VIM) on patients with medically refractory myoclonus dystonia (MD). BACKGROUND:More recently, pallidal as well as thalamic DBS have been appli...

journal_title：European journal of neurology

authors： Krause P,Koch K,Gruber D,Kupsch A,Gharabaghi A,Schneider GH,Kühn AA

更新日期：2021-01-16 00:00:00

abstract：:Multiple sclerosis (MS) is a T-cell-mediated autoimmune demyelinating disease of the central nervous system, associated with an altered cytokine network. We previously assayed peripheral blood T-lymphocyte binding for two prototypic cytokines, tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and foun...

journal_title：European journal of neurology

authors： Bongioanni P,Lombardo F,Moscato G,Mosti S,Meucci G

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Various breathing abnormalities (Neurology 2009; 73: 1218) have been proposed as indicators for the introduction of non-invasive positive-pressure ventilation (NIV) in patients with amyotrophic lateral sclerosis (ALS). We were interested in the usefulness of symptoms of respiratory insufficiency and abnormal...

journal_title：European journal of neurology

authors： Leonardis L,Dolenc Grošelj L,Vidmar G

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Alternating hemiplegia of childhood (AHC) is a rare neurological disease characterized by recurrent paroxysmal attacks of hemiplegia. The aim of the study was to assess the recovery cycle of the somatosensory evoked potentials (SEPs) in a group of AHC patients. METHODS:Seven AHC patients and 10 ...

journal_title：European journal of neurology

authors： Vollono C,Rinalduzzi S,Miliucci R,Vigevano F,Valeriani M

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mutations in the PLA2G6 gene are causative of PLA2G6-associated neurodegeneration (PLAN), a spectrum of neurodegenerative conditions including infantile, childhood and adult onset forms. METHODS:Seventeen North African patients with a clinical suspicion of infantile-onset PLAN underwent clinical...

journal_title：European journal of neurology

authors： Romani M,Kraoua I,Micalizzi A,Klaa H,Benrhouma H,Drissi C,Turki I,Castellana S,Mazza T,Valente EM,Gouider-Khouja N

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acute severe exacerbations of myasthenia gravis (MG) are common in both early and late onset MG. We wished to examine the current management in the intensive care unit (ICU) of severe exacerbations of MG and to study the long-term prognosis of MG following discharge from the ICU. METHODS:We retr...

journal_title：European journal of neurology

authors： Spillane J,Hirsch NP,Kullmann DM,Taylor C,Howard RS

更新日期：2014-01-01 00:00:00

abstract：:In recent years, a number of potential new therapeutic indications of botulinum toxin injections have emerged, amongst which sialorrhea has attracted considerable attention. Based on open-label and controlled studies, botulinum toxin can be used to improve sialorrhea in patients with Parkinson's disease, parkinsonian ...

journal_title：European journal of neurology

authors： Tan EK

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of our study was to describe patients with the p.D12Y variant (previously reported as D11Y) in SOD1 showing heterogeneous clinicopathological features. METHODS:We performed clinical, electrophysiological, magnetic resonance imaging (MRI) and muscle pathology studies in four SOD1 p.D12Y v...

journal_title：European journal of neurology

authors： Tasca G,Lattante S,Marangi G,Conte A,Bernardo D,Bisogni G,Mandich P,Zollino M,Ragozzino E,Udd B,Sabatelli M

更新日期：2020-07-01 00:00:00

abstract：:To evaluate prevalence of use and prescribing patterns of antiepileptic drugs (AEDs) in Italian general practice. Primary care data were obtained from the Health Search Database, a longitudinal observational database implemented by the Italian College of General Practitioners (GPs). We selected 465 061 subjects regist...

journal_title：European journal of neurology

authors： Savica R,Beghi E,Mazzaglia G,Innocenti F,Brignoli O,Cricelli C,Caputi AP,Musolino R,Spina E,Trifirò G

更新日期：2007-12-01 00:00:00

abstract：:Glyceryl trinitrate, a prodrug of nitric oxide, induces a mild to moderate headache in healthy subjects, whilst migraineurs develop a more severe headache, resembling spontaneous migraine attacks. In order to investigate whether this increased nitric oxide sensitivity depends upon the frequency of spontaneously occurr...

journal_title：European journal of neurology

authors： Christiansen I,Daugaard D,Lykke Thomsen L,Olesen J

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Consensus guidelines on the definition, investigation, and treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) have been previously published in European Journal of Neurology and Journal of the Peripheral Nervous System. OBJECTIVES:To revise these guidelines. METHODS:Disease exper...

journal_title：European journal of neurology

authors： Van den Bergh PY,Hadden RD,Bouche P,Cornblath DR,Hahn A,Illa I,Koski CL,Léger JM,Nobile-Orazio E,Pollard J,Sommer C,van Doorn PA,van Schaik IN,European Federation of Neurological Societies.,Peripheral Nerve Society.

更新日期：2010-03-01 00:00:00

abstract：:The presence of white matter lesions (WML) is an important prognostic factor for the development of stroke. Plasma total homocysteine (tHcy), which increases with diabetes, has been flagged as a novel predictor for cerebrovascular events. We tested the hypothesis that the presence of WML correlates with tHcy and insul...

journal_title：European journal of neurology

authors： Shimomura T,Anan F,Umeno Y,Eshima N,Saikawa T,Yoshimatsu H,Fujiki M,Kobayashi H

更新日期：2008-03-01 00:00:00

abstract：:Progression of atherosclerosis at extracranial carotid and intracranial arteries in patients with ischemic heart disease (IHD) is not well defined. We carried out a 5-year longitudinal study with magnetic resonance angiography (MRA) of patients with IHD to assess the incidence of progression of atherosclerosis at extr...

journal_title：European journal of neurology

authors： Uehara T,Tabuchi M,Mori E,Yamadori A

更新日期：2003-09-01 00:00:00

abstract：:A case is described in which non-convulsive status epilepticus (NCSE) prompted further investigation leading to the diagnosis of Lafora body disease (LBD). The onset of NCSE was temporally related to the withdrawal of sodium valproate and introduction of carbamazepine, which may have been precipitating factors. NCSE h...

journal_title：European journal of neurology

authors： Corkill RG,Hardie RJ

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The National Institute for Health and Care Excellence (NICE) in the UK recommends the use of OnabotulinumtoxinA (BoNTA, Botox® ) in the management of chronic migraine (CM) following specific guidelines within the National Health Service. In view of the lack of data on the efficacy of this therapy...

journal_title：European journal of neurology

authors： Andreou AP,Trimboli M,Al-Kaisy A,Murphy M,Palmisani S,Fenech C,Smith T,Lambru G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Charcot-Marie-Tooth (CMT) disease is a chronic, slowly progressing disorder. The lack of specific disease progression biomarkers limits the execution of clinical trials. However, neurofilament light chain (NfL) has been suggested as a potential biomarker for peripheral nervous system disorders. ...

journal_title：European journal of neurology

authors： Millere E,Rots D,Simrén J,Ashton NJ,Kupats E,Micule I,Priedite V,Kurjane N,Blennow K,Gailite L,Zetterberg H,Kenina V

更新日期：2020-12-19 00:00:00

abstract：:We performed a 2-year population-based study on status epilepticus (SE) in adults in the rural area of Lugo di Romagna, northern Italy, to verify whether an area of low-level urbanization has a lower risk of occurrence of SE (as recently suggested), different clinical features and short-term prognosis than areas of hi...

journal_title：European journal of neurology

authors： Vignatelli L,Rinaldi R,Galeotti M,de Carolis P,D'Alessandro R

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Soluble ST2 (sST2) is a promising biomarker in inflammation, atherosclerosis and cardiovascular diseases. We investigated the association between serum sST2 and poor outcome in patients with transient ischaemic attack (TIA)/ischaemic stroke. METHODS:Patients within 24 h after onset and with meas...

journal_title：European journal of neurology

authors： Tian X,Guo Y,Wang X,Pei L,Wang X,Wu J,Sun S,Li Y,Ning M,Buonanno FS,Xu Y,Song B

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Motor symptoms form the hallmark of Parkinson's Disease (PD), although features like depression are often present. Depression rating scales [e.g. Montgomery-Asberg Depression Rating Scale (MADRS)] used in PD measure affective, cognitive and somatic symptoms. An important clinical question is which items of t...

journal_title：European journal of neurology

authors： Koerts J,Leenders KL,Koning M,Bouma A,van Beilen M

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that repetitive transcranial magnetic stimulation (rTMS) can reduce chronic tinnitus. However, treatment results are characterized by high interindividual variability. Therefore, the identification of predictors for treatment response is of high clinical relevance. METHODS:Clini...

journal_title：European journal of neurology

authors： Frank G,Kleinjung T,Landgrebe M,Vielsmeier V,Steffenhagen C,Burger J,Frank E,Vollberg G,Hajak G,Langguth B

更新日期：2010-07-01 00:00:00

abstract：:An evaluation of general antiepileptic treatment patterns and utilization of particular drugs was carried out based on the prevalence study of adult active epilepsy in a sample of the Estonian population. The antiepileptic drugs (AEDs) used, and their doses were recorded and compared with clinical characteristics. Nin...

journal_title：European journal of neurology

authors： Oun A,Haldre S,Mägi M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although there is growing and convincing evidence that socially deprived patients are at higher risk of stroke and worse outcomes, it remains controversial whether or not they suffer more severe stroke. This study aimed to evaluate the influence of social deprivation on initial clinical severity ...

journal_title：European journal of neurology

authors： Béjot Y,Guilloteau A,Joux J,Lannuzel A,Mimeau E,Mislin-Tritsch C,Fournel I,Bonithon-Kopp C,INDIA Study Group.

更新日期：2017-05-01 00:00:00

abstract：:The Oslo Multiple Sclerosis (MS) Registry was established in 1990, and this is the first report on the prevalence and incidence of MS in the city of Oslo, Norway. The prevalence rate of definite MS on 1 January 1995 was 120.4/10(5). Inclusion of patients of native Norwegian ancestry only and exclusion of non-Norwegian...

journal_title：European journal of neurology

authors： Celius EG,Vandvik B

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with the cerebellar variant of multiple system atrophy (MSA-C) often show cognitive deficits in various cognitive domains. The association between morphometric changes in cortical and subcortical structures and cognitive impairments in MSA-C were investigated to explore the neural correl...

journal_title：European journal of neurology

authors： Lee MJ,Shin JH,Seoung JK,Lee JH,Yoon U,Oh JH,Jung DS,Kim EJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Educating the public to screen for vascular risk factors and have them treated is a major public health issue. We assessed the vascular risk factor awareness and frequency of treatment in a cohort of patients with cerebral ischaemia. METHODS:Data on awareness and pharmacological treatment of vas...

journal_title：European journal of neurology

authors： Nolte CH,Jungehulsing GJ,Rossnagel K,Roll S,Haeusler KG,Reich A,Willich SN,Villringer A,Muller-Nordhorn J

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To evaluate the incidence and predictors of ischaemic recurrent stroke and the adverse events of antithrombotic therapy in patients with first intra- or extracranial vertebral artery dissection (VAD) who were treated with aspirin or oral anticoagulation (OA). METHODS:A 21-year database of consec...

journal_title：European journal of neurology

authors： Arauz A,Ruiz A,Pacheco G,Rojas P,Rodríguez-Armida M,Cantú C,Murillo-Bonilla L,Ruiz-Sandoval JL,Barinagarrementeria F

更新日期：2013-01-01 00:00:00

abstract：:We here present the case of a patient with a sleep disturbance attributed to the exploding head syndrome, recently redefined as 'episodic cranial sensory shock'. The patient, who suffered with concomitant migraine, was treated for headache prevention with daily single-pulse transcranial magnetic stimulation. Following...

journal_title：European journal of neurology

authors： Puledda F,Moreno-Ajona D,Goadsby PJ

更新日期：2021-01-18 00:00:00

abstract：:We report here 39 cases in which definite multiple sclerosis (MS) was precipitated or exacerbated by specific hyperextension-hyperflexion cervical cord trauma. The worsening or onset of the symptomatic disease bore a striking temporal relationship to the focal injury. Our data suggests that central nervous system (CNS...

journal_title：European journal of neurology

authors： Chaudhuri A,Behan PO

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The involvement of metabolic factors in the development of dementia has received much attention. However, previous studies have yielded conflicting results regarding how blood adipocytokine level impacts cognitive decline and dementia. This study aimed to clarify whether serum high-molecular-weig...

journal_title：European journal of neurology

authors： Kitagawa K,Miwa K,Okazaki S,Sakaguchi M,Mochizuki H

更新日期：2016-03-01 00:00:00