Abstract:
:We performed a 2-year population-based study on status epilepticus (SE) in adults in the rural area of Lugo di Romagna, northern Italy, to verify whether an area of low-level urbanization has a lower risk of occurrence of SE (as recently suggested), different clinical features and short-term prognosis than areas of high-level urbanization. We found crude and age- and sex-adjusted annual incidence rates of SE of 16.5/100 000 and 11.6/100 000, respectively. In patients under 60 years crude incidence was 2.9/100 000 and in the elderly (>/=60 years) 38.6/100 000. Acute symptomatic SE accounted for 30% and a cerebrovascular pathology was the most frequently associated etiologic condition (60%). A history of seizures was reported in 41% of patients. The first therapeutic intervention was mainly benzodiazepines (lorazepam 46%; diazepam 33%). The 30-day case fatality was 7%. We observed that the adult population of an area with a low level of urbanization has the same risk for SE, clinical features and short-term prognosis as European urban areas. The only contrasting result is the 30-day case fatality of 7% against the 39% found in the other Italian study (Bologna), despite the similarity of the SE features in these two areas of the same region. We infer that the short-term prognosis of SE could also be considerably influenced by differences in health service organization (and hence management) possibly due to different levels of urbanization.
journal_name
Eur J Neuroljournal_title
European journal of neurologyauthors
Vignatelli L,Rinaldi R,Galeotti M,de Carolis P,D'Alessandro Rdoi
10.1111/j.1468-1331.2005.01073.xsubject
Has Abstractpub_date
2005-11-01 00:00:00pages
897-902issue
11eissn
1351-5101issn
1468-1331pii
ENE1073journal_volume
12pub_type
信件abstract:BACKGROUND AND PURPOSE:Anxiety is potentially a pre-motor symptom of Parkinson's disease (PD). Our aim was to investigate the association between anxiety and subsequent PD risk in a population-based sample. METHODS:A total of 174 776 participants, who were free of prior PD, dementia and stroke, were enrolled from Taiw...
journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/ene.12740
更新日期:2015-09-01 00:00:00
abstract::Abnormal neuronal intermediate filament (IF) inclusions immunopositive for the type IV IF alpha-internexin have been identified as the pathological hallmark of neuronal intermediate filament inclusion disease (NIFID). We studied the topography of these inclusions in the frontal and temporal lobe in 68 areas from 10 ca...
journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/j.1468-1331.2006.01284.x
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Body mass index (BMI), hyperglycaemia and type 2 diabetes and their interactive effects are associated with brain volume atrophy in ageing. It remains to be established if these risk factors are particularly concerning in individuals with high or low brain volumes. METHODS:Demographics, venous b...
journal_title:European journal of neurology
pub_type: 杂志文章
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journal_title:European journal of neurology
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doi:10.1111/ene.12289
更新日期:2014-02-01 00:00:00
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journal_title:European journal of neurology
pub_type: 临床试验,杂志文章
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更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:Chronic progressive external ophthalmoplegia (CPEO) is a relatively common mitochondrial disorder. In addition to extraocular muscle weakness, various other organs can typically be affected, including laryngeal and limb muscles, cerebrum, cerebellum, and peripheral nerves. Given this multi-organ involvement,...
journal_title:European journal of neurology
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更新日期:2012-01-01 00:00:00
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journal_title:European journal of neurology
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更新日期:2002-05-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:European journal of neurology
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1046/j.1351-5101.2003.00707.x
更新日期:2004-01-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章,随机对照试验
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更新日期:2014-08-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/ene.13273
更新日期:2017-05-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1046/j.1468-1331.1998.550499.x
更新日期:1998-09-01 00:00:00
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journal_title:European journal of neurology
pub_type: 临床试验,杂志文章
doi:10.1046/j.1468-1331.1999.640461.x
更新日期:1999-07-01 00:00:00
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journal_title:European journal of neurology
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更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Falling is considered an important public health problem among older people. A recent cross-sectional study suggested that cognitive frailty (CF) is associated with falls. We aimed to explore whether CF is a risk factor for falls in a population-based longitudinal study. METHODS:Using data from ...
journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/ene.14572
更新日期:2021-02-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1046/j.1468-1331.2003.00605.x
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To evaluate the association between having non-thymoma myasthenia and the risk of extra-thymic cancer in a population-based setting. METHODS:A nationwide case-control study was conducted in Denmark based on medical registries. The study included all cases with a first time diagnosis of cancer du...
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/ene.12881
更新日期:2016-02-01 00:00:00
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journal_title:European journal of neurology
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doi:10.1046/j.1468-1331.2000.00071.x
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:CACNA1S encodes Cav 1.1, a voltage sensor for muscle excitation-contraction coupling, which activates the ryanodine receptor 1 (RYR1) leading to calcium release from the sarcoplasmic reticulum. CACNA1S mutations cause hypokalemic periodic paralysis, malignant hyperthermia and congenital myopathy....
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pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2012-06-01 00:00:00
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pub_type: 杂志文章,实务指引
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更新日期:2015-02-01 00:00:00
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journal_title:European journal of neurology
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/j.1468-1331.1995.tb00102.x
更新日期:1995-04-01 00:00:00
abstract::There is paucity of studies on predictors of long-term sequelae of tuberculous meningitis (TBM). We report the neurological sequelae of TBM at 1 year and their predictors. Patients with TBM who were followed up for 1 year were included. The diagnosis of TBM was based on clinical, cerebrospinal fluid (CSF) and computed...
journal_title:European journal of neurology
pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00