Abstract:
BACKGROUND AND PURPOSE:Portugal has been identified as one of the countries with a high prevalence of LRRK2-G2019S, considered to be the most frequent known cause of familial and sporadic Parkinson's disease (PD). The aim of this study was to evaluate the prevalence of PD in Portugal using a door-to-door methodology. METHODS:A cross-sectional study was conducted in the Portuguese community-dwelling population; that is, elderly people living in the community on their own, aged ≥50 years and resident in mainland Portugal, in two phases: (i) a questionnaire was applied to screen potential cases of PD; and (ii) screened cases were evaluated by an expert in PD to confirm diagnosis. RESULTS:The adjusted prevalence of PD for the Portuguese community-dwelling population aged ≥50 years was 0.24%. The estimated total number of cases of PD for the Portuguese population is 180/100 000 inhabitants. CONCLUSIONS:The results of this study show that a geographical region with a high frequency of a causal mutation for PD does not automatically imply a high prevalence of patients with PD.
journal_name
Eur J Neuroljournal_title
European journal of neurologyauthors
Ferreira JJ,Gonçalves N,Valadas A,Januário C,Silva MR,Nogueira L,Vieira JLM,Lima ABdoi
10.1111/ene.13273subject
Has Abstractpub_date
2017-05-01 00:00:00pages
748-750issue
5eissn
1351-5101issn
1468-1331journal_volume
24pub_type
杂志文章abstract:BACKGROUND AND PURPOSE:Concerning the great importance of brainstem involvement in multiple sclerosis (MS), the aim of this study was to explore the role of the newly developed vestibular evoked myogenic potentials (VEMP) score as a possible marker of brainstem involvement in MS patients. PATIENTS AND METHODS:This was...
journal_title:European journal of neurology
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更新日期:2015-02-01 00:00:00
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journal_title:European journal of neurology
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journal_title:European journal of neurology
pub_type: 杂志文章
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更新日期:2007-09-01 00:00:00
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journal_title:European journal of neurology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:European journal of neurology
pub_type: 杂志文章
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journal_title:European journal of neurology
pub_type:
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journal_title:European journal of neurology
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journal_title:European journal of neurology
pub_type: 杂志文章,随机对照试验
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/ene.14715
更新日期:2021-01-05 00:00:00
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journal_title:European journal of neurology
pub_type: 信件
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更新日期:2001-03-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章,评审
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更新日期:2013-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2004-02-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章,随机对照试验
doi:10.1111/ene.12344
更新日期:2014-03-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/ene.12057
更新日期:2013-04-01 00:00:00
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journal_title:European journal of neurology
pub_type: 杂志文章
doi:10.1111/j.1468-1331.1997.tb00297.x
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更新日期:2000-05-01 00:00:00
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journal_title:European journal of neurology
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