Quantitation of intrathecal immunoglobulin synthesis - a new empirical formula.

abstract：BACKGROUND AND PURPOSE:The purpose was to evaluate the association between the left ventricular ejection fraction (LVEF) and cerebral small vessel disease (cSVD) in ischaemic stroke patients. METHODS:Consecutive first-ever ischaemic stroke patients between 2010 and 2013 were included. White matter hyperintensity (WMH)...

journal_title：European journal of neurology

authors： Nam KW,Kwon HM,Kim HL,Lee YS

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Basilar artery occlusion (BAO) leads to high rates of morbidity and mortality, despite successful recanalization. The discordance between flow restoration and long-term functional status clouds clinical decision-making regarding further aggressive care. We sought to develop and validate a practic...

journal_title：European journal of neurology

authors： Jadhav AP,Desai SM,Panczykowski DM,Rangaraju S,Campbell D,Ritvonen JK,Schreiner M,Silvennoinen H,Gerber J,Puetz V,Raza SA,Haussen DC,Nogueira RG,Strbian D,Jovin TG,Lindsberg PJ

更新日期：2020-11-01 00:00:00

abstract：:Phosphorylated α-synuclein (phosαSYN) containing inclusions in neurons (Lewy bodies, LB) and nerve terminals (Lewy neurites, LN), the pathological hallmark of Parkinson's disease (PD), are not confined to the central nervous system, but have also been reported in peripheral tissues. However, the usefulness of αSYN/pho...

journal_title：European journal of neurology

authors： Schneider SA,Boettner M,Alexoudi A,Zorenkov D,Deuschl G,Wedel T

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although erenumab has demonstrated significant reduction in migraine frequency and improved quality of life in studies lasting 3 to 12 months, little is known about long-term therapy. METHODS:This study was an open-label, 5-year treatment phase following a 12-week, double-blind, placebo-controll...

journal_title：European journal of neurology

authors： Ashina M,Goadsby PJ,Reuter U,Silberstein S,Dodick DW,Xue F,Zhang F,Paiva da Silva Lima G,Cheng S,Mikol DD

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the genetic contribution to stroke risk is well known, it remains unclear if young-onset stroke has a stronger genetic contribution than old-onset stroke. This study aims to compare the heritability of ischaemic stroke risk between young and old, using common genetic variants from whole-...

journal_title：European journal of neurology

authors： Bluher A,Devan WJ,Holliday EG,Nalls M,Parolo S,Bione S,Giese AK,Boncoraglio GB,Maguire JM,Müller-Nurasyid M,Gieger C,Meschia JF,Rosand J,Rolfs A,Kittner SJ,Mitchell BD,O'Connell JR,Cheng YC

更新日期：2015-11-01 00:00:00

abstract：:We performed a placebo-controlled cross-over trial of riluzole (100 mg b.i.d.) in 10 patients with probable multiple system atrophy (MSA) administering riluzole and placebo for 4 weeks each with a 4-week washout period. Outcome measures evaluated short-term anti-Parkinsonian effects using the Unified Parkinson's Disea...

journal_title：European journal of neurology

authors： Seppi K,Peralta C,Diem-Zangerl A,Puschban Z,Mueller J,Poewe W,Wenning GK

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous disease. In addition to the traditional clinical triad, there is also a diversity of clinical signs, and it may be related to other systemic diseases. METHODS:In the present study, we report a case of MRS with endocrine disorders ...

journal_title：European journal of neurology

authors： Wang S,Wang H,Shi X,Wu F,Lv L,Hu M,Sun W,Wu L,Zhou H

更新日期：2020-12-03 00:00:00

abstract：:Recent studies suggest an association between Chlamydia pneumoniae infection with atherosclerosis, including cerebrovascular disease. We investigated the prevalence of Chlamydial seropositivity in patients with acute ischaemic stroke syndrome compared with age- and sex-matched control subjects. Specific antibodies (Ig...

journal_title：European journal of neurology

authors： Madre JG,Garcia JL,Gonzalez RC,Montero JM,Paniagua EB,Escribano JR,Martinez JD,Cenjor RF

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In multiple sclerosis (MS), disease-related factors and dysfunctional coping might favor the development of mental distress induced by COVID-19 containment measures. Aim of this study was exploring the relationship between disability, coping strategies, daily life reorganization and neuropsychiat...

journal_title：European journal of neurology

authors： Costabile T,Carotenuto A,Lavorgna L,Borriello G,Moiola L,Inglese M,Petruzzo M,Trojsi F,Ianniello A,Nozzolillo A,Cellerino M,Boffa G,Rosa L,Servillo G,Moccia M,Bonavita S,Filippi M,Lanzillo R,Brescia Morra V,Petracca

更新日期：2020-10-11 00:00:00

abstract：BACKGROUND AND PURPOSE:Anosognosia refers to a deficit of self-awareness or impaired insight for cognitive and behavioral problems. Cognitive anosognosia was explored in de novo patients with Parkinson's disease (PD) and its relationship to cognitive function and neuropsychiatric symptoms was investigated. METHODS:The...

journal_title：European journal of neurology

authors： Yoo HS,Chung SJ,Lee YH,Ye BS,Sohn YH,Lee PH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Venous drainage of dural arteriovenous fistula (DAVF) with dementia has never been reported. The aim of this study was to discover if specific vascular conditions exist to develop dementia in patients with DAVF. METHODS:Venous drainage in patients embolized in our centre between 1996 and 2012 fo...

journal_title：European journal of neurology

authors： Labeyrie MA,Lenck S,Saint-Maurice JP,Bresson D,Houdart E

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Oxidative stress is a central factor in the pathogenesis of Parkinson's disease (PD). Heme oxygenase-1 (HO-1) is an antioxidant protein expressed in response to oxidative challenge, and its expression levels are inversely correlated with glycogen synthase kinase-3beta (GSK3beta) activity. Underexpression of ...

journal_title：European journal of neurology

authors： Infante J,García-Gorostiaga I,Sánchez-Juan P,Sierra M,Martín-Gurpegui JL,Terrazas J,Mateo I,Rodríguez-Rodríguez E,Berciano J,Combarros O

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND: Myasthenia gravis (MG) is an autoimmune disorder mediated by antibodies against the acethylcholine receptor (AchR) of the neuromuscular junction in the majority of patients. METHODS: Here, we examined IgG antibodies against the type 1 nuclear antigen of Epstein-Barr virus (EBNA-1) in the sera of 158 patien...

journal_title：European journal of neurology

authors： Csuka D,Banati M,Rozsa C,Füst G,Illes Z

更新日期：2012-06-01 00:00:00

abstract：:Population-based data on the incidence, aetiology, and mortality associated with status epilepticus (SE) are required to develop preventative strategies for SE. Through a systematic review, we aimed to assess the methodological quality as well as similarities, and differences between available population based studies...

journal_title：European journal of neurology

authors： Chin RF,Neville BG,Scott RC

更新日期：2004-12-01 00:00:00

abstract：:Cytokines have a central role in multiple sclerosis (MS) pathogenesis and may contribute to the aetiology of MS. A polymorphism in the IFNA17 gene with an allele carrying a pre-mature stop codon has been suggested to convey a 26-fold increased risk for MS. We investigated the possible association between this polymorp...

journal_title：European journal of neurology

authors： Nyström M,Ruuth K,Lundgren E,Sundström P

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Migraine and metabolic syndrome have been reported to coexist to a marked degree, especially in women migraine patients, but the relationship between these two conditions is still unclear. This study was performed to evaluate the association of headache characteristics and its comorbidities with ...

journal_title：European journal of neurology

authors： He Z,Dong L,Zhang Y,Kong Q,Tan G,Zhou J

更新日期：2015-08-01 00:00:00

abstract：:In the international neurological literature, neuroimaging research plays an important role. Neuroimaging techniques are also of steadily increasing importance for clinical diagnosis and treatment monitoring. Therefore, neuroimaging research activities were surveyed by a questionnaire, which was completed by 100 neuro...

journal_title：European journal of neurology

authors： Herholz K,Perani D,Fazekas F,Markus H,Baumgartner RW,Baron JC

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:The burden of multiple sclerosis (MS) includes fatigue, depression and worsening of health-related quality of life (HRQOL). These changes have not been yet measured in neuromyelitis optica (NMO). Our aim was to assess the HRQOL, fatigue and depression in NMO. METHODS:We administered French validated self-qu...

journal_title：European journal of neurology

authors： Chanson JB,Zéphir H,Collongues N,Outteryck O,Blanc F,Fleury M,Vermersch P,de Seze J

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:People with multiple sclerosis (MS) have to face important decisions with regard to their medical treatment. The aim of this study was to evaluate whether a targeted cognitive training reduces framing effects and thus improves medical judgments. METHODS:This was a randomized, double-blind, cross...

journal_title：European journal of neurology

authors： Zamarian L,Delazer M,Ehling R,Pertl MT,Bsteh G,Wenter J,Glatzl S,Brenneis C,Benke T,Berger T

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Variations in the treatment of multiple sclerosis (MS) occur. This study was performed to obtain insight into the reasons why patients with MS use or do not use immunomodulating treatment (DMT). METHODS:We held a survey on the use of DMT in a group of 1572 patients with MS. RESULTS:Response rate was 89%. O...

journal_title：European journal of neurology

authors： Visser LH,van der Zande A

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Serotoninergic dysfunction was reported to be involved in aetiology of temporal lobe epilepsy (TLE). Serotonin (5-HT) is actively cleared from synaptic cleft by serotonin transporter (5-HTT). We investigated the association between three common polymorphisms of 5-HTT gene, which may influence gen...

journal_title：European journal of neurology

authors： Li J,Lin H,Zhu X,Li L,Wang X,Sun W,Wu X,Liu A,Niu F,Wang Y,Liu Y

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Headache has been associated with various lifestyle and psychosocial factors, one of which is smoking. The aim of the present study was to investigate whether the association between smoking intensity and headache is likely to be causal. METHOD:A total of 58 316 participants from the Nord-Trønde...

journal_title：European journal of neurology

authors： Johnsen MB,Winsvold BS,Børte S,Vie GÅ,Pedersen LM,Storheim K,Skorpen F,Hagen K,Bjørngaard JH,Åsvold BO,Zwart JA

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Efficacy and safety data have not previously been compiled for intramuscular interferon beta-1a (IM IFNβ-1a) in patients with multiple sclerosis (MS) ≥ 50 years of age. We investigated the efficacy and safety of IM IFNβ-1a in patients segregated by 50 and 40 years of age in separate meta-analyses. METHODS:T...

journal_title：European journal of neurology

authors： Lampl C,You X,Limmroth V

更新日期：2012-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a risk factor for cardiovascular disorders and different types of stroke. The present retrospective study investigates whether COPD is also a risk factor for the development of seizures in stroke patients. The study population consisted of 237 patients with stroke-relate...

journal_title：European journal of neurology

authors： De Reuck J,Proot P,Van Maele G

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few recent data are available concerning idiopathic optic neuritis (ON). We aimed to describe a large cohort of patients with idiopathic ON. We compared this cohort with patients with ON related to myelin oligodendrocyte glycoprotein (MOG) or ON related to aquaporin-4 (AQP4) antibodies. METHODS:...

journal_title：European journal of neurology

authors： Deschamps R,Gueguen A,Lecler A,Lecouturier K,Lamirel C,Bensa C,Marignier R,Vignal C,Gout O

更新日期：2018-11-01 00:00:00

abstract：:Frontotemporal dementia (FTD) often presents with behavioural changes warranting treatment with antipsychotic medications. It is known that patients with Lewy body dementia are sensitive to developing extrapyramidal symptoms (EPS) from these medications. This has not been emphasized in FTD. We report three patients wi...

journal_title：European journal of neurology

authors： Czarnecki K,Kumar N,Josephs KA

更新日期：2008-02-01 00:00:00

abstract：:Multiple sclerosis (MS) is a T-cell-mediated autoimmune demyelinating disease of the central nervous system, associated with an altered cytokine network. We previously assayed peripheral blood T-lymphocyte binding for two prototypic cytokines, tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and foun...

journal_title：European journal of neurology

authors： Bongioanni P,Lombardo F,Moscato G,Mosti S,Meucci G

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The expanded repeat length in ATXN1 negatively correlates with age at onset (AAO) of spinocerebellar ataxia type 1 (SCA1) but can explain only part of it, indicating that other factors affect AAO. Some studies have explored the influence of non-causative CAG repeats on the AAO of SCA patients. Ho...

journal_title：European journal of neurology

authors： Wang P,Chen Z,Peng Y,Cao L,Li X,Wang C,Yang H,Peng H,Shi Y,Zhou X,Li T,Feng L,Wu C,Qiu R,Xia K,Tang B,Jiang H

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Conversion disorder (CD), or functional neurological disorder, is manifested as a neurological disturbance that is not macroscopically visible on clinical structural neuroimaging and is instead ascribed to underlying psychological stress. Known for many years in neuropsychiatry, a comprehensive e...

journal_title：European journal of neurology

authors： Monsa R,Peer M,Arzy S

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Risk-stratification models based on patient and disease characteristics are useful for aiding clinical decisions and for comparing the quality of care between different physicians or hospitals. In addition, prediction of mortality is beneficial for optimizing resource utilization. We evaluated th...

journal_title：European journal of neurology

authors： Peng SY,Chuang YC,Kang TW,Tseng KH

更新日期：2010-07-01 00:00:00