Synergistic effect of two oxidative stress-related genes (heme oxygenase-1 and GSK3β) on the risk of Parkinson's disease.

abstract：:Twelve patients with early Parkinson's disease (PD), none of whom had received any previous L-DOPA treatment, but using other antiparkinsonian drugs, were studied using transcranial magnetic stimulation (TMS). Contralateral and ipsilateral hemispheres were examined, with a focus on the more pronounced parkinsonian sym...

journal_title：European journal of neurology

authors： Bares M,Kanovský P,Klajblová H,Rektor I

更新日期：2003-07-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a risk factor for cardiovascular disorders and different types of stroke. The present retrospective study investigates whether COPD is also a risk factor for the development of seizures in stroke patients. The study population consisted of 237 patients with stroke-relate...

journal_title：European journal of neurology

authors： De Reuck J,Proot P,Van Maele G

更新日期：2007-09-01 00:00:00

abstract：:A 53-year-old man presented with optic neuritis, followed within 10 weeks by a subacute progression of weakness, ataxia, and multiple cranial nerve palsies. Cranial magnetic resonance imaging demonstrated multiple T2-hyperintense lesions extending from the ponto-medullary junction to the thalamus and internal capsule....

journal_title：European journal of neurology

authors： Zivković SA,Heyman R,Pless M

更新日期：2003-01-01 00:00:00

abstract：:Recently, diagnostic clinical and imaging criteria for primary progressive aphasia (PPA) have been revised by an international consortium (Gorno-Tempini et al. Neurology 2011;76:1006-14). The aim of this study was to validate the specificity of the new imaging criteria and investigate whether different imaging modalit...

journal_title：European journal of neurology

authors： Bisenius S,Neumann J,Schroeter ML

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Clinical presentation and DYT1 status amongst Chinese patients with primary dystonia have not been well studied. METHODS:One hundred and twenty patients with primary dystonia from South-West China were studied in a prospective survey for 3.5 years. Severity and the resulting disability were assessed using t...

journal_title：European journal of neurology

authors： Zhang SS,Fang DF,Hu XH,Burgunder JM,Chen XP,Zhang YW,Shang HF

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of cardiovascular risk factors in the pathogenesis of cognitive impairment and dementia remains still unclear. We examined the impact of cardiovascular risk factors on cognitive function in a large longitudinal population study. METHODS:Subjects were 5033 stroke-free men and women who p...

journal_title：European journal of neurology

authors： Arntzen KA,Schirmer H,Wilsgaard T,Mathiesen EB

更新日期：2011-05-01 00:00:00

abstract：:The levels of malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD-1) were measured in the red blood cells (RBC) of 34 patients with acute ischemic hemispheric stroke on the first and seventh day after their stroke onset, and compared with 30 control individuals matched for sex, age and...

journal_title：European journal of neurology

authors： Demirkaya S,Topcuoglu MA,Aydin A,Ulas UH,Isimer AI,Vural O

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The expanded repeat length in ATXN1 negatively correlates with age at onset (AAO) of spinocerebellar ataxia type 1 (SCA1) but can explain only part of it, indicating that other factors affect AAO. Some studies have explored the influence of non-causative CAG repeats on the AAO of SCA patients. Ho...

journal_title：European journal of neurology

authors： Wang P,Chen Z,Peng Y,Cao L,Li X,Wang C,Yang H,Peng H,Shi Y,Zhou X,Li T,Feng L,Wu C,Qiu R,Xia K,Tang B,Jiang H

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Venous drainage of dural arteriovenous fistula (DAVF) with dementia has never been reported. The aim of this study was to discover if specific vascular conditions exist to develop dementia in patients with DAVF. METHODS:Venous drainage in patients embolized in our centre between 1996 and 2012 fo...

journal_title：European journal of neurology

authors： Labeyrie MA,Lenck S,Saint-Maurice JP,Bresson D,Houdart E

更新日期：2014-03-01 00:00:00

abstract：:No studies have prospectively investigated headache at onset of first-ever ischemic stroke along with a large concurrent control group. Our aims were to answer two important questions: (i) Are headaches at stroke onset causally related to the stroke, and what are their typical clinical characteristics? (ii) What etiol...

journal_title：European journal of neurology

authors： Lebedeva ER,Ushenin AV,Gurary NM,Tsypushkina TS,Gilev DV,Kislyak NV,Olesen J

更新日期：2020-12-16 00:00:00

abstract：:A 45 year-old man presented with a rapid onset of memory impairment Brain computed tomography showed multiple abnormal low density areas in the deep cerebral white matter. Magnetic resonance imaging revealed bilateral thalamic infarcts and extensive thrombosis of the vein of Galen and the straight sinus, which was con...

journal_title：European journal of neurology

authors： Daif AK,Awada A,Rajeh SA,Andeejani A

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Better understanding the incidence, predictors and mechanisms of early neurological deterioration (END) following intravenous thrombolysis (IVT) for acute stroke with mild symptoms and isolated internal carotid artery occlusion (iICAo) may inform therapeutic decisions. METHODS:From a multicenter...

journal_title：European journal of neurology

authors： Boulenoir N,Turc G,Henon H,Laksiri N,Mounier-Véhier F,Girard Buttaz I,Duong DL,Papassin J,Yger M,Triquenot A,Lyoubi A,Ter Schiphorst A,Denier C,Baron JC,Seners P,MINOR-STROKE Collaborators.

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A transient ischemic attack (TIA) can occur without self-awareness of symptoms. We aimed to investigate characteristics of patients with a tissue-based diagnosis of TIA but having no self-awareness of their symptoms and whose symptoms were witnessed by bystanders. METHODS:We used data from the m...

journal_title：European journal of neurology

authors： Tanaka K,Uehara T,Ohara T,Sato S,Hayakawa M,Kimura K,Okada Y,Hasegawa Y,Tanahashi N,Suzuki A,Nakagawara J,Arii K,Nagahiro S,Ogasawara K,Uchiyama S,Matsumoto M,Iihara K,Toyoda K,Minematsu K,PROMISE-TIA study Investig

更新日期：2021-02-01 00:00:00

abstract：:There are about 25.7 million stroke survivors worldwide. Ischaemic stroke remains the most common type of stroke. Numerous modifiable risk factors have been identified, including behaviors such as cigarette smoking and sedentary lifestyle and treatable medical comorbidities such as hypertension, hyperlipidemia and atr...

journal_title：European journal of neurology

authors： Meschia JF,Brott T

更新日期：2018-01-01 00:00:00

abstract：:The role of genetics and its technological development have been fundamental in advancing the field of movement disorders, opening the door to precision medicine. Starting from the revolutionary discovery of the locus of the Huntington's disease gene, we review the milestones of genetic discoveries in movement disorde...

journal_title：European journal of neurology

authors： Sturchio A,Marsili L,Mahajan A,Grimberg MB,Kauffman MA,Espay AJ

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS)-related genes and mutations have been increasingly discovered recently and an improved understanding of genotype-phenotype relationships may help to predict the disease course and refine genetic diagnosis. METHODS:We collected clinical data and blood samples f...

journal_title：European journal of neurology

authors： Chen W,Xie Y,Zheng M,Lin J,Huang P,Pei Z,Yao X

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our objective was to study the association between serum levels of anti Epstein-Barr virus nuclear antigen 1 (EBNA-1) antibody and 25-hydroxyvitamin D (25(OH)D) in a prospective cohort of patients with relapsing-remitting multiple sclerosis. METHOD:The study comprised 90 patients with relapsing-...

journal_title：European journal of neurology

authors： Wergeland S,Myhr KM,Løken-Amsrud KI,Beiske AG,Bjerve KS,Hovdal H,Midgard R,Kvistad SS,Holmøy T,Riise T,Torkildsen Ø

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cognitive impairment (CI) is found in about half of the multiple sclerosis (MS) population and is an important contributor to employment status and social functioning. CI is encountered in all disease stages and correlates only moderately with disease duration or Expanded Disability Status Scale ...

journal_title：European journal of neurology

authors： Van Schependom J,D'hooghe MB,Cleynhens K,D'hooge M,Haelewyck MC,De Keyser J,Nagels G

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cognitive impairment is common in Parkinson's disease (PD), even in the early stages. We aimed to assess the relationship between insulin-like growth factor-1 (IGF-1) and cognitive functions in early, drug-naïve patients with PD. METHODS:Serum IGF-1 was measured in 65 early, drug-naïve patients ...

journal_title：European journal of neurology

authors： Pellecchia MT,Santangelo G,Picillo M,Pivonello R,Longo K,Pivonello C,Vitale C,Amboni M,De Rosa A,Moccia M,Erro R,De Michele G,Santoro L,Colao A,Barone P

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately 9000 people in the UK are affected by Huntington's disease (HD). People with HD require ongoing health and social care support. There is a knowledge gap about costs of health and social care use associated with HD in the UK. This paper estimates the economic cost in the UK. METHODS...

journal_title：European journal of neurology

authors： Jones C,Busse M,Quinn L,Dawes H,Drew C,Kelson M,Hood K,Rosser A,Edwards RT

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Behçet's disease (BD) is a multisystemic, recurrent, inflammatory disorder. Neurological involvement is well-known but cerebral vasculitis and ischaemic stroke are unusual. CASE DESCRIPTION:A 43-year-old male patient presented with acute left hemiparesis, he had recurrent oral aphthae and scrotal ulcerati...

journal_title：European journal of neurology

authors： Krespi Y,Akman-Demir G,Poyraz M,Tugcu B,Coban O,Tuncay R,Serdaroglu P,Bahar S

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increased arterial stiffness causes vessel damage in the end-organs. Therefore small vessels in the brain may be susceptible to increased arterial stiffness. Cerebral microbleeds (CMBs) are topographically or pathophysiologically categorized as deep or infratentorial type and strictly lobar type....

journal_title：European journal of neurology

authors： Song TJ,Kim J,Kim YD,Nam HS,Lee HS,Nam CM,Heo JH

更新日期：2014-03-01 00:00:00

abstract：:It is not well established whether seizures and epilepsy after an ischaemic stroke increase the disability of patients. Seventy-two patients with delayed seizures after a hemispheric infarct (37 with a single seizure and 35 with epilepsy) were included in the study. The modified Rankin scale was used to compare disabi...

journal_title：European journal of neurology

authors： De Reuck J,Claeys I,Martens S,Vanwalleghem P,Van Maele G,Phlypo R,Hallez H

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sporadic amyotrophic lateral sclerosis (sALS) is a disease with a focal clinical onset and contiguous spread. We examined patterns of disease spread following symptoms onset in sALS and whether the pattern of spread predicted survival. METHODS:Review of medical records (2003-2009) at London Onta...

journal_title：European journal of neurology

authors： Gargiulo-Monachelli GM,Janota F,Bettini M,Shoesmith CL,Strong MJ,Sica RE

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Alternating hemiplegia of childhood (AHC) is a rare neurological disease characterized by recurrent paroxysmal attacks of hemiplegia. The aim of the study was to assess the recovery cycle of the somatosensory evoked potentials (SEPs) in a group of AHC patients. METHODS:Seven AHC patients and 10 ...

journal_title：European journal of neurology

authors： Vollono C,Rinalduzzi S,Miliucci R,Vigevano F,Valeriani M

更新日期：2014-12-01 00:00:00

abstract：:We here present the case of a patient with a sleep disturbance attributed to the exploding head syndrome, recently redefined as 'episodic cranial sensory shock'. The patient, who suffered with concomitant migraine, was treated for headache prevention with daily single-pulse transcranial magnetic stimulation. Following...

journal_title：European journal of neurology

authors： Puledda F,Moreno-Ajona D,Goadsby PJ

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND AND PURPOSE:Improved biomarkers are needed to facilitate clinical decision-making and as surrogate endpoints in clinical trials in multiple sclerosis (MS). We assessed whether neurodegenerative and neuroinflammatory markers in cerebrospinal fluid (CSF) at initial sampling could predict disease activity durin...

journal_title：European journal of neurology

authors： Håkansson I,Tisell A,Cassel P,Blennow K,Zetterberg H,Lundberg P,Dahle C,Vrethem M,Ernerudh J

更新日期：2017-05-01 00:00:00

abstract：:Population-based data on the incidence, aetiology, and mortality associated with status epilepticus (SE) are required to develop preventative strategies for SE. Through a systematic review, we aimed to assess the methodological quality as well as similarities, and differences between available population based studies...

journal_title：European journal of neurology

authors： Chin RF,Neville BG,Scott RC

更新日期：2004-12-01 00:00:00

abstract：:Moyamoya angiopathy (MA) is a progressive cerebrovascular disease with a poorly understood pathophysiology. It is mainly characterized by progressive bilateral stenosis of the terminal intracranial part of the supraclinoid internal carotid arteries and the proximal parts of the middle and anterior cerebral arteries, a...

journal_title：European journal of neurology

authors： Mitri F,Bersano A,Hervé D,Kraemer M

更新日期：2021-01-23 00:00:00

abstract：:We performed a 2-year population-based study on status epilepticus (SE) in adults in the rural area of Lugo di Romagna, northern Italy, to verify whether an area of low-level urbanization has a lower risk of occurrence of SE (as recently suggested), different clinical features and short-term prognosis than areas of hi...

journal_title：European journal of neurology

authors： Vignatelli L,Rinaldi R,Galeotti M,de Carolis P,D'Alessandro R

更新日期：2005-11-01 00:00:00