(CAG)n loci as genetic modifiers of age at onset in patients with spinocerebellar ataxia type 1 from mainland China.

abstract：BACKGROUND AND PURPOSE:Friedreich's ataxia (FRDA) is the most common autosomal-recessive ataxia worldwide. It is characterized by early onset, sensory abnormalities and slowly progressive ataxia. All magnetic resonance imaging (MRI)-based studies have focused on the evaluation of adult patients. Therefore, we designed ...

journal_title：European journal of neurology

authors： Rezende TJR,Martinez ARM,Faber I,Girotto Takazaki KA,Martins MP,de Lima FD,Lopes-Cendes I,Cendes F,França MC Jr

更新日期：2019-03-01 00:00:00

abstract：:Digital subtraction angiography (DSA) is considered to be the 'gold standard' for confirmation of severe (70-99%) stenoses of internal carotid arteries (ICAs). However, it is associated with a risk of complications. The aim of this study was to assess the accuracy of ultrasonography (US), computed tomographic angiogra...

journal_title：European journal of neurology

authors： Herzig R,Burval S,Krupka B,Vlachová I,Urbánek K,Mares J

更新日期：2004-11-01 00:00:00

abstract：:There are about 25.7 million stroke survivors worldwide. Ischaemic stroke remains the most common type of stroke. Numerous modifiable risk factors have been identified, including behaviors such as cigarette smoking and sedentary lifestyle and treatable medical comorbidities such as hypertension, hyperlipidemia and atr...

journal_title：European journal of neurology

authors： Meschia JF,Brott T

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Portugal has been identified as one of the countries with a high prevalence of LRRK2-G2019S, considered to be the most frequent known cause of familial and sporadic Parkinson's disease (PD). The aim of this study was to evaluate the prevalence of PD in Portugal using a door-to-door methodology. ...

journal_title：European journal of neurology

authors： Ferreira JJ,Gonçalves N,Valadas A,Januário C,Silva MR,Nogueira L,Vieira JLM,Lima AB

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Detection of occult atrial fibrillation (AF) is crucial for optimal secondary prevention in stroke patients. The AF detection rate was determined by implantable cardiac monitor (ICM) and compared to the prediction rate of the probability of incident AF by software based analysis of a continuously...

journal_title：European journal of neurology

authors： Reinke F,Bettin M,Ross LS,Kochhäuser S,Kleffner I,Ritter M,Minnerup J,Dechering D,Eckardt L,Dittrich R

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The involvement of metabolic factors in the development of dementia has received much attention. However, previous studies have yielded conflicting results regarding how blood adipocytokine level impacts cognitive decline and dementia. This study aimed to clarify whether serum high-molecular-weig...

journal_title：European journal of neurology

authors： Kitagawa K,Miwa K,Okazaki S,Sakaguchi M,Mochizuki H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mutations in the PLA2G6 gene are causative of PLA2G6-associated neurodegeneration (PLAN), a spectrum of neurodegenerative conditions including infantile, childhood and adult onset forms. METHODS:Seventeen North African patients with a clinical suspicion of infantile-onset PLAN underwent clinical...

journal_title：European journal of neurology

authors： Romani M,Kraoua I,Micalizzi A,Klaa H,Benrhouma H,Drissi C,Turki I,Castellana S,Mazza T,Valente EM,Gouider-Khouja N

更新日期：2015-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic and potentially highly disabling disorder with considerable social impact and economic consequences. It is the major cause of non-traumatic disability in young adults. The social costs associated with MS are high because of its long duration, the early loss of productivity, the nee...

journal_title：European journal of neurology

authors： Pugliatti M,Rosati G,Carton H,Riise T,Drulovic J,Vécsei L,Milanov I

更新日期：2006-07-01 00:00:00

abstract：:Allodynia--perception of pain from non-noxious stimuli--is a common clinical feature in various pain syndromes. The significance for migraine has increasingly been recognized and the pathophysiology has been investigated in detail. Allodynia is a marker for sensitization of central trigeminal neurons. Intensity and pe...

journal_title：European journal of neurology

authors： Schürks M,Diener HC

更新日期：2008-12-01 00:00:00

abstract：:The report focused on investigating the relationship between cigarette smoking and dementia in elderly people through prospective studies. We did a 2-year follow-up study of elderly people. A total of 2820 participants aged 60 years old and over from six communities of Chongqing agreed to take part. Dementia was diagn...

journal_title：European journal of neurology

authors： Juan D,Zhou DH,Li J,Wang JY,Gao C,Chen M

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intrathecal immunoglobulin (Ig) synthesis occurs in various chronic inflammatory neurological diseases. Different formulae have been developed for quantitative determination of Ig synthesis within the cerebrospinal fluid (CSF) compartment. The hyperbolic formula of Reiber is frequently used which...

journal_title：European journal of neurology

authors： Auer M,Hegen H,Zeileis A,Deisenhammer F

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our objective was to study the association between serum levels of anti Epstein-Barr virus nuclear antigen 1 (EBNA-1) antibody and 25-hydroxyvitamin D (25(OH)D) in a prospective cohort of patients with relapsing-remitting multiple sclerosis. METHOD:The study comprised 90 patients with relapsing-...

journal_title：European journal of neurology

authors： Wergeland S,Myhr KM,Løken-Amsrud KI,Beiske AG,Bjerve KS,Hovdal H,Midgard R,Kvistad SS,Holmøy T,Riise T,Torkildsen Ø

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multinodular and vacuolating neuronal tumor (MVNT) of the cerebrum is a rare brain lesion with suggestive imaging features. The aim of our study was to report the largest series of MVNTs so far and to evaluate the utility of advanced multiparametric magnetic resonance (MR) techniques. METHODS:Th...

journal_title：European journal of neurology

authors： Lecler A,Broquet V,Bailleux J,Carsin B,Adle-Biassette H,Baloglu S,Forestier G,Bonneville F,Calvier E,Chauvet D,Comby PO,Cottier JP,Cotton F,Deschamps R,Diard-Detoeuf C,Ducray F,Drissi C,Elmaleh M,Farras J,Aguilar Ga

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:People with multiple sclerosis (MS) have to face important decisions with regard to their medical treatment. The aim of this study was to evaluate whether a targeted cognitive training reduces framing effects and thus improves medical judgments. METHODS:This was a randomized, double-blind, cross...

journal_title：European journal of neurology

authors： Zamarian L,Delazer M,Ehling R,Pertl MT,Bsteh G,Wenter J,Glatzl S,Brenneis C,Benke T,Berger T

更新日期：2019-01-01 00:00:00

abstract：:Between March 1996 and December 1997, 15 consecutive patients with carotid artery occlusion diagnosed with duplex sonography were treated with intravenous recombinant tissue plasminogen activator (rt-PA), following a protocol similar to that of the National Institute of Neurological Disorders and Stroke (NINDS) study....

journal_title：European journal of neurology

authors： Rudolf J,Neveling M,Grond M,Schmulling S,Stenzel C,Heiss WD

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Predicting the course of behavioural variant frontotemporal dementia (bvFTD) remains a major clinical challenge. This study aimed to identify factors that predict survival and clinical progression in bvFTD. METHODS:Consecutive patients with clinically probable bvFTD were prospectively followed u...

journal_title：European journal of neurology

authors： Agarwal S,Ahmed RM,D'Mello M,Foxe D,Kaizik C,Kiernan MC,Halliday GM,Piguet O,Hodges JR

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this prospective study was to show and compare the rate of large-fiber involvement with near-nerve needle sensory (NNNS) nerve conduction study (NCS) and with medial plantar NCS recorded with surface electrodes in a group of patients who had clinically pure small-fiber sensory neuropat...

journal_title：European journal of neurology

authors： Uluc K,Temucin CM,Ozdamar SE,Demirci M,Tan E

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To evaluate the incidence and predictors of ischaemic recurrent stroke and the adverse events of antithrombotic therapy in patients with first intra- or extracranial vertebral artery dissection (VAD) who were treated with aspirin or oral anticoagulation (OA). METHODS:A 21-year database of consec...

journal_title：European journal of neurology

authors： Arauz A,Ruiz A,Pacheco G,Rojas P,Rodríguez-Armida M,Cantú C,Murillo-Bonilla L,Ruiz-Sandoval JL,Barinagarrementeria F

更新日期：2013-01-01 00:00:00

abstract：:Phosphorylated α-synuclein (phosαSYN) containing inclusions in neurons (Lewy bodies, LB) and nerve terminals (Lewy neurites, LN), the pathological hallmark of Parkinson's disease (PD), are not confined to the central nervous system, but have also been reported in peripheral tissues. However, the usefulness of αSYN/pho...

journal_title：European journal of neurology

authors： Schneider SA,Boettner M,Alexoudi A,Zorenkov D,Deuschl G,Wedel T

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:To investigate changes in serum complements and their regulators in the pathogenesis of myasthenia gravis (MG). METHODS:Forty-four patients with acetylcholine receptor antibody-positive MG, as well as 20 patients with non-inflammatory neurological disorders were enrolled. Serum complements (C3, C4 and solubl...

journal_title：European journal of neurology

authors： Ozawa Y,Uzawa A,Yasuda M,Kojima Y,Oda F,Himuro K,Kawaguchi N,Kuwabara S

更新日期：2021-01-01 00:00:00

abstract：:We describe a case of cardiac myxoma whose clinical presentation mimicked that of polyarteritis nodosa. The serum levels of MPO-ANCA and IL-6 were elevated on laboratory investigation and normalized after the removal of the tumor. We suggest that a 'true' vasculitic mechanism contributes to the pathogenesis of pseudov...

journal_title：European journal of neurology

authors： Nishio Y,Ito Y,Iguchi Y,Sato H

更新日期：2005-08-01 00:00:00

abstract：:Post-marketing surveillance studies are needed to assess the long-term safety, compliance and clinical efficacy of interferon beta-1a (IFNbeta-1a) therapy in multiple sclerosis (MS) patients. The goals of this study were to (i) assess the safety, compliance and clinical efficacy of long-term intramuscular (i.m.) IFNbe...

journal_title：European journal of neurology

authors： Coppola G,Lanzillo R,Florio C,Orefice G,Vivo P,Ascione S,Schiavone V,Pagano A,Vacca G,De Michele G,Morra VB

更新日期：2006-09-01 00:00:00

abstract：:The aim of this study was to compare the seizure outcome of two different types of epilepsy surgery, selective amygdalohippocampectomy (AHE) and anterior temporal lobectomy (ATLE) in patients with temporal lobe epilepsy. We included 114 patients who had mesio-temporal lobe epilepsy and hippocampal sclerosis or gliosis...

journal_title：European journal of neurology

authors： Bate H,Eldridge P,Varma T,Wieshmann UC

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional connectivity studies revealed alterations within thalamic, salience, and default mode networks in restless legs syndrome patients. METHODS:Eighty-two patients with restless legs syndrome (untreated, n = 30; on dopaminergic medication, n = 42; on alpha-2-delta ligands as mono- or polyt...

journal_title：European journal of neurology

authors： Tuovinen N,Stefani A,Mitterling T,Heidbreder A,Frauscher B,Gizewski ER,Poewe W,Högl B,Scherfler C

更新日期：2021-02-01 00:00:00

abstract：:A comprehensive battery of neuropsychological tests sampling a wide range of cognitive functions was administrated to 36 patients with systemic lupus erythematosus (SLE), and a control group consisting of 31 patients with persistent symptoms after whiplash injury. Our results demonstrated significant group differences...

journal_title：European journal of neurology

authors： Waterloo K,Omdal R,Mellgren SI,Husby G

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cognitive impairment is common in Parkinson's disease (PD), even in the early stages. We aimed to assess the relationship between insulin-like growth factor-1 (IGF-1) and cognitive functions in early, drug-naïve patients with PD. METHODS:Serum IGF-1 was measured in 65 early, drug-naïve patients ...

journal_title：European journal of neurology

authors： Pellecchia MT,Santangelo G,Picillo M,Pivonello R,Longo K,Pivonello C,Vitale C,Amboni M,De Rosa A,Moccia M,Erro R,De Michele G,Santoro L,Colao A,Barone P

更新日期：2014-05-01 00:00:00

abstract：:Hypoalbuminemia is associated with increased risk of infections. The aim of this study was to determine if serum albumin level is an independent predictor of nosocomial pneumonia in stroke patients. Data of 705 consecutive ischemic stroke patients admitted within 24 h after stroke onset were analyzed retrospectively. ...

journal_title：European journal of neurology

authors： Dziedzic T,Pera J,Klimkowicz A,Turaj W,Slowik A,Rog TM,Szczudlik A

更新日期：2006-03-01 00:00:00

abstract：:Complex painful reflex syndrome is sometimes described in the chronic phase of stroke. Acute autonomic dysfunction (AAD), which is occasionally present in cases of acute stroke, has not been studied prospectively. The aim of the study was to investigate AAD on the hemibody contralateral to the lesion in the acute phas...

journal_title：European journal of neurology

authors： Diserens K,Vuadens P,Michel P,Reichhart M,Herrmann FR,Arnold P,Bogousslavsky J,Ghika J

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Frontotemporal dementia (FTD) is a degenerative disorder characterized, in its frontal variant, by psychiatric onset, deficits in executive functions and sparing of memory and visuo-spatial abilities. Studies on visuo-spatial abilities in FTD and Alzheimer's disease (AD) have mainly focused on co...

journal_title：European journal of neurology

authors： Gasparini M,Masciarelli G,Vanacore N,Ottaviani D,Salati E,Talarico G,Lenzi GL,Bruno G

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clinically isolated syndrome (CIS) is a first demyelinating event of the central nervous system and can be a single event. After CIS, a chronic disease course with ongoing inflammation and relapses might occur, resulting in a diagnosis of multiple sclerosis (MS). As yet, there has been no prospec...

journal_title：European journal of neurology

authors： van der Vuurst de Vries RM,van Pelt ED,Mescheriakova JY,Wong YY,Ketelslegers IA,Siepman TA,Catsman CE,Neuteboom RF,Hintzen RQ

更新日期：2017-02-01 00:00:00