Subacute rhombencephalitis optica responsive to intravenous immunoglobulins.

Abstract:

:A 53-year-old man presented with optic neuritis, followed within 10 weeks by a subacute progression of weakness, ataxia, and multiple cranial nerve palsies. Cranial magnetic resonance imaging demonstrated multiple T2-hyperintense lesions extending from the ponto-medullary junction to the thalamus and internal capsule. Cerebrospinal fluid analysis showed lymphocytic pleocytosis with elevated protein content. A brain biopsy revealed inflammatory changes. After a month long period of inexorable worsening, the patient was treated with intravenous immunoglobulins (2 g/kg). He responded to treatment, and recovered over the subsequent 3 months. The patient's response to treatment suggests that intravenous immunoglobulins should be considered in patients with inflammatory brain disorders.

journal_name

Eur J Neurol

authors

Zivković SA,Heyman R,Pless M

doi

10.1046/j.1468-1331.2003.00543.x

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

83-6

issue

1

eissn

1351-5101

issn

1468-1331

pii

543

journal_volume

10

pub_type

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