Mini-Mental State Examination: a normative study in Italian elderly population.

abstract：:Therapy-induced binding and neutralizing antibodies is a major problem in interferon (IFN)-beta treatment of multiple sclerosis. The objective of this study was to provide guidelines outlining the methods and clinical use of the measurements of binding and neutralizing antibodies. Systematic search of the Medline data...

journal_title：European journal of neurology

authors： Sørensen PS,Deisenhammer F,Duda P,Hohlfeld R,Myhr KM,Palace J,Polman C,Pozzilli C,Ross C,EFNS Task Force on Anti-IFN-beta Antibodies in Multiple Sclerosis.

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Haemorrhagic transformation (HT) is common after acute ischaemic stroke. Whether liver function plays a role in HT remains an open question. METHODS:Acute ischaemic stroke patients within 7 days from stroke onset were included. Baseline data including liver function tests were collected. An inde...

journal_title：European journal of neurology

authors： Tan G,Lei C,Hao Z,Chen Y,Yuan R,Liu M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Essential tremor (ET) is the most common movement disorder worldwide. Three susceptibility loci on chromosomes 3q13, 2p24.1, and 6p23 have been reported, but no causative genes were found. The Ser9Gly variant of dopamine D3 receptor (DRD3) receptor was found associated to ET in a French and US population. M...

journal_title：European journal of neurology

authors： Vitale C,Gulli R,Ciotti P,Scaglione C,Bellone E,Avanzino L,Lantieri F,Abbruzzese G,Martinelli P,Barone P,Mandich P

更新日期：2008-09-01 00:00:00

abstract：:We here present the case of a patient with a sleep disturbance attributed to the exploding head syndrome, recently redefined as 'episodic cranial sensory shock'. The patient, who suffered with concomitant migraine, was treated for headache prevention with daily single-pulse transcranial magnetic stimulation. Following...

journal_title：European journal of neurology

authors： Puledda F,Moreno-Ajona D,Goadsby PJ

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND AND PURPOSE:Magnetic resonance diffusivity indices have been repeatedly proposed as biomarkers of neurodegeneration in amyotrophic lateral sclerosis (ALS), but no consensus exists as to which diffusivity parameter is the most sensitive to identify early degenerative changes. Despite numerous studies, surpris...

journal_title：European journal of neurology

authors： Schuster C,Elamin M,Hardiman O,Bede P

更新日期：2016-08-01 00:00:00

abstract：:Hereditary spastic paraparesis (HSP) is a heterogeneous group of neurodegenerative disorders with progressive lower limb spasticity, categorized into pure (p-HSP) and complicated forms (c-HSP). The purpose of this study was to evaluate if brain volumes in HSP were altered compared with a control population. Brain volu...

journal_title：European journal of neurology

authors： Kassubek J,Sperfeld AD,Baumgartner A,Huppertz HJ,Riecker A,Juengling FD

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our aim was to identify early imaging surrogate markers of clinical progression in patients after the first demyelinating event suggestive of multiple sclerosis treated with weekly intramuscular interferon β-1a. In a prospective observational study, the predictive role of baseline and 6-month cha...

journal_title：European journal of neurology

authors： Uher T,Horakova D,Kalincik T,Bergsland N,Tyblova M,Ramasamy DP,Seidl Z,Vaneckova M,Krasensky J,Havrdova E,Zivadinov R

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few recent data are available concerning idiopathic optic neuritis (ON). We aimed to describe a large cohort of patients with idiopathic ON. We compared this cohort with patients with ON related to myelin oligodendrocyte glycoprotein (MOG) or ON related to aquaporin-4 (AQP4) antibodies. METHODS:...

journal_title：European journal of neurology

authors： Deschamps R,Gueguen A,Lecler A,Lecouturier K,Lamirel C,Bensa C,Marignier R,Vignal C,Gout O

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to examine the association amongst remote diffusion-weighted imaging lesions (R-DWILs), imaging markers of cerebral small vessel disease (cSVD) and total cSVD burden in patients with primary intracerebral haemorrhage (ICH). METHODS:In total, 344 consecutive primary ICH ...

journal_title：European journal of neurology

authors： Xu XH,Ye XH,Li JW,Cai JS,Gao T,Zhang WJ,Zhao GH,Tong LS,Gao F

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acute severe exacerbations of myasthenia gravis (MG) are common in both early and late onset MG. We wished to examine the current management in the intensive care unit (ICU) of severe exacerbations of MG and to study the long-term prognosis of MG following discharge from the ICU. METHODS:We retr...

journal_title：European journal of neurology

authors： Spillane J,Hirsch NP,Kullmann DM,Taylor C,Howard RS

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Paraprotein-associated neuropathies have heterogeneous clinical, neurophysiological, neuropathological and haematological features. Objectives. To prepare evidence-based and consensus guidelines on the clinical management of patients with both a demyelinating neuropathy and a paraprotein (paraproteinaemic de...

journal_title：European journal of neurology

authors： European Federation of Neurological Societies.,Peripheral Nerve Society.,Hadden RD,Nobile-Orazio E,Sommer C,Hahn A,Illa I,Morra E,Pollard J,Hughes RA,Bouche P,Cornblath D,Evers E,Koski CL,Léger JM,Van den Bergh P,van Door

更新日期：2006-08-01 00:00:00

abstract：:Malignancy-related thromboembolism, so-called Trousseau's syndrome, can present as acute cerebral infarction, non-bacterial thrombotic endocarditis (NBTE) and migratory thrombophlebitis. It is usually attributed to a cancer-related hypercoagulable state, chronic disseminated intravascular coagulopathy (DIC), or tumour...

journal_title：European journal of neurology

authors： Tasi SH,Juan CJ,Dai MS,Kao WY

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite numerous studies, the role of patent foramen ovale (PFO) as a risk factor for stroke due to paradoxical embolism is still controversial. On the assumption that specific lesion patterns, in particular multiple acute ischaemic lesions on diffusion-weighted magnetic resonance imaging, indica...

journal_title：European journal of neurology

authors： Feurer R,Sadikovic S,Esposito L,Schwarze J,Bockelbrink A,Hemmer B,Sander D,Poppert H

更新日期：2009-10-01 00:00:00

abstract：:Botulinum A toxin (BT) has been successfully used for the management of spasticity in cerebral palsy (CP). However, the long-term results of BT have not yet been determined. We have studied the evolution of a homogeneous group of patients with CP treated with BT. All these patients had an equinus gait resulting from c...

journal_title：European journal of neurology

authors： García Ruiz PJ,Pascual Pascual I,Sánchez Bernardos V

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Charcot-Marie-Tooth (CMT) disease is a chronic, slowly progressing disorder. The lack of specific disease progression biomarkers limits the execution of clinical trials. However, neurofilament light chain (NfL) has been suggested as a potential biomarker for peripheral nervous system disorders. ...

journal_title：European journal of neurology

authors： Millere E,Rots D,Simrén J,Ashton NJ,Kupats E,Micule I,Priedite V,Kurjane N,Blennow K,Gailite L,Zetterberg H,Kenina V

更新日期：2020-12-19 00:00:00

abstract：BACKGROUND AND PURPOSE:In contrast to anterior circulation stroke (ACS), there is no evidence from randomized trials that mechanical thrombectomy (MT) with modern stent retrievers or thromboaspiration is safe and effective in posterior circulation stroke (PCS). METHODS:The present analysis was based on the prospective...

journal_title：European journal of neurology

authors： Weber R,Minnerup J,Nordmeyer H,Eyding J,Krogias C,Hadisurya J,Berger K,REVASK investigators.

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis of cytomegalovirus encephalitis (CMV-E) in AIDS patients is challenging as other illnesses may obscure the symptoms. Here, we characterize the clinical symptoms of CMV-E and link them to post-mortem findings. Patients and methods In 254 homosexual men with AIDS, followed from HIV di...

journal_title：European journal of neurology

authors： Pirskanen-Matell R,Grützmeier S,Nennesmo I,Sandström E,Ehrnst A

更新日期：2009-01-01 00:00:00

abstract：:To study the efficacy and safety of tolperisone - a centrally acting muscle relaxant with membrane stabilizing activity - in the treatment of stroke-related spasticity. This was a randomized, double-blind, placebo-controlled, multicenter study with parallel groups. Treatment lasted 12 weeks and was started with a titr...

journal_title：European journal of neurology

authors： Stamenova P,Koytchev R,Kuhn K,Hansen C,Horvath F,Ramm S,Pongratz D

更新日期：2005-06-01 00:00:00

abstract：:We used 123I-Ioflupane SPECT to study striatal dopamine transporter (DAT) binding in 36 Parkinson's disease (PD) patients with history of severe occupational exposure to hydrocarbons. Data were compared with 38 PD patients without exposure history as well as healthy controls. Both PD cohorts showed significant striata...

journal_title：European journal of neurology

authors： Canesi M,Benti R,Marotta G,Cilia R,Isaias IU,Gerundini P,Pezzoli G,Antonini A

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In patients with spinal muscular atrophy (SMA), functional disease scores are frequently used to evaluate the course of the disease and the efficacy of treatment. The aim of the present study was to propose minimal clinically important difference (MCID) values for motor scores in order to estimat...

journal_title：European journal of neurology

authors： Stolte B,Bois JM,Bolz S,Kizina K,Totzeck A,Schlag M,Kleinschnitz C,Hagenacker T

更新日期：2020-12-01 00:00:00

abstract：:There are about 25.7 million stroke survivors worldwide. Ischaemic stroke remains the most common type of stroke. Numerous modifiable risk factors have been identified, including behaviors such as cigarette smoking and sedentary lifestyle and treatable medical comorbidities such as hypertension, hyperlipidemia and atr...

journal_title：European journal of neurology

authors： Meschia JF,Brott T

更新日期：2018-01-01 00:00:00

abstract：:We present the baseline characteristics of 101 patients with normal pressure hydrocephalus (NPH), entering a study that evaluates the diagnostic reliability of CSF outflow resistance. Patients were assessed by a gait scale consisting of 10 features of walking and the number of steps and seconds necessary for 10 m, a d...

journal_title：European journal of neurology

authors： Boon AJ,Tans JT,Delwel EJ,Egeler-Peerdeman SM,Hanlo PW,Wurzer JA,Hermans J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS) is classically assumed to be a neurodegenerative disorder. Inflammation has been observed in CNS tissue in ALS patients. We investigated the expression and prognostic relevance of proinflammatory chemokines in ALS. METHODS:We analyzed nine chemokines, eotaxin,...

journal_title：European journal of neurology

authors： Kuhle J,Lindberg RL,Regeniter A,Mehling M,Steck AJ,Kappos L,Czaplinski A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our objective was to study the association between serum levels of anti Epstein-Barr virus nuclear antigen 1 (EBNA-1) antibody and 25-hydroxyvitamin D (25(OH)D) in a prospective cohort of patients with relapsing-remitting multiple sclerosis. METHOD:The study comprised 90 patients with relapsing-...

journal_title：European journal of neurology

authors： Wergeland S,Myhr KM,Løken-Amsrud KI,Beiske AG,Bjerve KS,Hovdal H,Midgard R,Kvistad SS,Holmøy T,Riise T,Torkildsen Ø

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Superficial siderosis of the central nervous system is a sporadic finding in magnetic resonance imaging, resulting from recurrent bleedings into the subarachnoid space. This study aimed to determine the frequency of spinal dural cerebrospinal fluid (CSF) leaks amongst patients with a symmetric in...

journal_title：European journal of neurology

authors： Friedauer L,Rezny-Kasprzak B,Steinmetz H,du Mesnil de Rochemont R,Foerch C

更新日期：2020-10-24 00:00:00

abstract：:To determine whether eosinophils play a critical role in muscle fiber damage in patients with eosinophilic myositis (EM). We investigated expression of eosinophilic major basic protein (MBP) and interleukin (IL)-5 at the protein and mRNA levels in muscle biopsies from three patients with idiopathic EM. MBP deposits we...

journal_title：European journal of neurology

authors： Murata K,Sugie K,Takamure M,Fujimoto T,Ueno S

更新日期：2003-01-01 00:00:00

abstract：:We evaluated the cerebral hemodynamic features of severe bilateral carotid stenosis by assessing and comparing cerebral vasomotor reactivity (VMR) in the middle cerebral (MCA) and vertebral arteries (VA) by transcranial Doppler and the Diamox (1 g acetazolamide i.v.) test. VMR was evaluated by recording the percentage...

journal_title：European journal of neurology

authors： Gur AY,Bornstein NM

更新日期：2006-02-01 00:00:00

abstract：:There are at least seven clinically indistinguishable but genetically different types of autosomal dominant pure spastic paraplegia (ADPSP). In this study we investigated electrophysiological characteristics in patients with ADPSP linked to chromosome 2p (SPG4). Twelve patients from six different families with ADPSP l...

journal_title：European journal of neurology

authors： Nielsen JE,Jennum P,Fenger K,Sørensen SA,Fuglsang-Frederiksen A

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CACNA1A encodes the α1 subunit of the neuronal calcium channel P/Q. CACNA1A mutations underlie three allelic disorders: familial hemiplegic migraine type 1 (FHM1), episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6). A clear-cut genotype-phenotype correlation is often lacking si...

journal_title：European journal of neurology

authors： Indelicato E,Nachbauer W,Karner E,Eigentler A,Wagner M,Unterberger I,Poewe W,Delazer M,Boesch S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Body mass index (BMI), hyperglycaemia and type 2 diabetes and their interactive effects are associated with brain volume atrophy in ageing. It remains to be established if these risk factors are particularly concerning in individuals with high or low brain volumes. METHODS:Demographics, venous b...

journal_title：European journal of neurology

authors： Walsh EI,Shaw M,Sachdev P,Anstey KJ,Cherbuin N

更新日期：2019-01-01 00:00:00