Cerebellar tumour presenting with pathological laughter and gelastic syncope.

abstract：BACKGROUND AND PURPOSE:Serotoninergic dysfunction was reported to be involved in aetiology of temporal lobe epilepsy (TLE). Serotonin (5-HT) is actively cleared from synaptic cleft by serotonin transporter (5-HTT). We investigated the association between three common polymorphisms of 5-HTT gene, which may influence gen...

journal_title：European journal of neurology

authors： Li J,Lin H,Zhu X,Li L,Wang X,Sun W,Wu X,Liu A,Niu F,Wang Y,Liu Y

更新日期：2012-02-01 00:00:00

abstract：:The diagnosis of mitochondrial encephalomyopathies is complex and a system for classification of the diagnosis as definite, probable, and possible has been proposed. The objective of this study was to explore the spectrum of epileptic disorders associated with probable and definite mitochondrial disease in children us...

journal_title：European journal of neurology

authors： Sadleir LG,Connolly MB,Applegarth D,Hendson G,Clarke L,Rakshi C,Farrell K

更新日期：2004-02-01 00:00:00

abstract：:Multiple sclerosis (MS) is a T-cell-mediated autoimmune demyelinating disease of the central nervous system, associated with an altered cytokine network. We previously assayed peripheral blood T-lymphocyte binding for two prototypic cytokines, tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), and foun...

journal_title：European journal of neurology

authors： Bongioanni P,Lombardo F,Moscato G,Mosti S,Meucci G

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Disease-modifying therapies provide new horizons for hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) to slow neuropathic progression. Initiating treatment at the earliest time requires biomarkers reflecting both small- and large-fiber degeneration in carriers. METHODS:This st...

journal_title：European journal of neurology

authors： Chiang MC,Yeh TY,Sung JY,Hsueh HW,Kao YH,Hsueh SJ,Chang KC,Feng FP,Lin YH,Chao CC,Hsieh ST

更新日期：2020-12-28 00:00:00

abstract：BACKGROUND:The objective of this study was to clarify the influence of regional cerebral blood flow (rCBF) changes in language-relevant areas of the dominant hemisphere on rCBF in each region in the non-dominant hemisphere in post-stroke aphasic patients. METHODS:The study subjects were 27 aphasic patients who suffere...

journal_title：European journal of neurology

authors： Uruma G,Kakuda W,Abo M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Rapid eye movement sleep behaviour disorder (RBD) is related to striatal dopamine depletion. This study was performed to confirm whether clinically probable RBD (cpRBD) in patients with Parkinson's disease (PD) is associated with a specific pattern of striatal dopamine depletion. METHODS:A prosp...

journal_title：European journal of neurology

authors： Chung SJ,Lee Y,Lee JJ,Lee PH,Sohn YH

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Detection of occult atrial fibrillation (AF) is crucial for optimal secondary prevention in stroke patients. The AF detection rate was determined by implantable cardiac monitor (ICM) and compared to the prediction rate of the probability of incident AF by software based analysis of a continuously...

journal_title：European journal of neurology

authors： Reinke F,Bettin M,Ross LS,Kochhäuser S,Kleffner I,Ritter M,Minnerup J,Dechering D,Eckardt L,Dittrich R

更新日期：2018-04-01 00:00:00

abstract：:A 76-year-old man insidiously developed diffuse neurological symptoms: cognitive decline, dysphagia, dysphasia and mental disturbance. Computed tomography of the cranium revealed widespread bilateral brain edema and symmetrical bilateral sphenoid wing hyperostosis. Adjacent to the hyperostosis that resembled skull bas...

journal_title：European journal of neurology

authors： Lindsberg PJ,Tatlisumak T,Tienari J,Brander A

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Polymorphisms of the interleukin-1 (IL-1) gene family have been proposed as potential variants for different diseases including multiple sclerosis (MS). With respect to MS, IL-1 beta (-511 C/T; rs16944), IL-1 beta (+3954 C/T; rs1143634), IL-1 alpha (-889 C/T; rs1800587), IL-1 alpha (+4845 G/T; rs17561), and ...

journal_title：European journal of neurology

authors： Borzani I,Tola MR,Caniatti L,Collins A,De Santis G,Luiselli D,Mamolini E,Scapoli C

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Consensus guidelines on the definition, investigation, and treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) have been previously published in European Journal of Neurology and Journal of the Peripheral Nervous System. OBJECTIVES:To revise these guidelines. METHODS:Disease exper...

journal_title：European journal of neurology

authors： Van den Bergh PY,Hadden RD,Bouche P,Cornblath DR,Hahn A,Illa I,Koski CL,Léger JM,Nobile-Orazio E,Pollard J,Sommer C,van Doorn PA,van Schaik IN,European Federation of Neurological Societies.,Peripheral Nerve Society.

更新日期：2010-03-01 00:00:00

abstract：:Allodynia--perception of pain from non-noxious stimuli--is a common clinical feature in various pain syndromes. The significance for migraine has increasingly been recognized and the pathophysiology has been investigated in detail. Allodynia is a marker for sensitization of central trigeminal neurons. Intensity and pe...

journal_title：European journal of neurology

authors： Schürks M,Diener HC

更新日期：2008-12-01 00:00:00

abstract：:Visual recognition memory was assessed in terms of delay duration, memory load and amount of interference(s) in non-demented patients with Parkinson's disease (PD) using an automated delayed non-matching-to-sample (DNMS) task with trial-unique stimuli. Special attention was focused on the different cognitive functions...

journal_title：European journal of neurology

authors： Blanchet S,Marié RM,Dauvillier F,Landeau B,Benali K,Eustache F,Chavoix C

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:  A low ankle-brachial index (ABI) is predictive of peripheral arterial disease (PAD). For unknown reasons, patients with PAD demonstrate higher vascular mortality during follow-up than do those without. Initial stroke severity is a strong predictor of long-term outcome and may be different between patients ...

journal_title：European journal of neurology

authors： Lee DH,Kim J,Lee HS,Cha MJ,Kim YD,Nam HS,Nam CM,Heo JH

更新日期：2012-06-01 00:00:00

abstract：:At least 13 different disease entities affecting the central nervous system, peripheral nervous system and connective tissue of the skin or kidneys are associated with immunoglobulin G4 (IgG4) immune reactivity. IgG4 has always been considered a benign, non-inflammatory subclass of IgG, in contrast to the well-known c...

journal_title：European journal of neurology

authors： Huijbers MG,Querol LA,Niks EH,Plomp JJ,van der Maarel SM,Graus F,Dalmau J,Illa I,Verschuuren JJ

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non-motor symptoms, including cognitive deficits. Several magnetic resonance imaging approaches have been applied to investigate brain atrophy in PD. The aim of this study was to detect early structural cortical a...

journal_title：European journal of neurology

authors： Danti S,Toschi N,Diciotti S,Tessa C,Poletti M,Del Dotto P,Lucetti C

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anosognosia refers to a deficit of self-awareness or impaired insight for cognitive and behavioral problems. Cognitive anosognosia was explored in de novo patients with Parkinson's disease (PD) and its relationship to cognitive function and neuropsychiatric symptoms was investigated. METHODS:The...

journal_title：European journal of neurology

authors： Yoo HS,Chung SJ,Lee YH,Ye BS,Sohn YH,Lee PH

更新日期：2020-06-01 00:00:00

abstract：:The aim of this narrative review is to evaluate the pathogenesis, clinical features, diagnosis, treatment and prognosis of intracranial artery dissection (IAD). IAD is a rare and often unrecognized cause of stroke or subarachnoid haemorrhage (SAH), especially in young adults. Two types of IAD can be identified: a subi...

journal_title：European journal of neurology

authors： Sikkema T,Uyttenboogaart M,Eshghi O,De Keyser J,Brouns R,van Dijk JM,Luijckx GJ

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Prevalence rates of headache in multiple sclerosis (MS) patients varied widely in recent studies. This study aimed to investigate the 1 year prevalence of headache in MS compared with the general population. METHODS:Population-based case-control study in Germany. RESULTS:We included 491 patients with defin...

journal_title：European journal of neurology

authors： Putzki N,Pfriem A,Limmroth V,Yaldizli O,Tettenborn B,Diener HC,Katsarava Z

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia occurs in up to 50% of all patients with acute stroke. There is debate regarding which is the most effective screening tool in identifying aspiration in patients with acute stroke. We assessed the accuracy of the Sapienza Global Bedside Evaluation of Swallowing after Stroke (GLOBE-3S), ...

journal_title：European journal of neurology

authors： Toscano M,Viganò A,Rea A,Verzina A,Sasso D'Elia T,Puledda F,Longo L,Mancini V,Ruggiero M,Jannini TB,Giuliani G,Albino F,Altieri M,Vicenzini E,Fattapposta F,Pauri F,Giacomini P,Ruoppolo G,Di Piero V

更新日期：2019-04-01 00:00:00

abstract：:Painful diabetic peripheral neuropathy (DPN) is described as a superficial burning pain associated with other positive and/or negative sensory systems affecting the feet and lower extremities. It is one of the most commonly encountered neuropathic pain syndromes in clinical practice. Presentation may be complicated by...

journal_title：European journal of neurology

authors： Marchettini P,Teloni L,Formaglio F,Lacerenza M

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Information about metabolic comorbidities in patients with multiple sclerosis (MS) is scarce. Our aim was to examine the prevalence of the metabolic syndrome (MetS) and its components in patients with long duration of MS and significant disability. METHODS:Demographic and clinical data, weight, ...

journal_title：European journal of neurology

authors： Pinhas-Hamiel O,Livne M,Harari G,Achiron A

更新日期：2015-09-01 00:00:00

abstract：:Most patients with acute disseminated encephalomyelitis (ADEM) recover quickly under corticosteroid treatment and have a favourable long-term prognosis. We report on a young woman with acute onset of an extensive and solitary white-matter lesion in the left hemisphere. Fever, high pleocytosis and elevated protein in c...

journal_title：European journal of neurology

authors： Harloff A,Rauer S,Hofer M,Klisch J,Els T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The known monogenic forms of stroke are rare. The aim of this study was to analyze pedigrees of young stroke patients regarding possible monogenic cerebrovascular disease and to evaluate the possibility of genetic stroke in these families. This may contribute to a better understanding of disease ...

journal_title：European journal of neurology

authors： Ilinca A,Kristoffersson U,Soller M,Lindgren AG

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The burden of multiple sclerosis (MS) includes fatigue, depression and worsening of health-related quality of life (HRQOL). These changes have not been yet measured in neuromyelitis optica (NMO). Our aim was to assess the HRQOL, fatigue and depression in NMO. METHODS:We administered French validated self-qu...

journal_title：European journal of neurology

authors： Chanson JB,Zéphir H,Collongues N,Outteryck O,Blanc F,Fleury M,Vermersch P,de Seze J

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is a high incidence of sleep-disordered breathing (SDB) in narcoleptic patients. Some narcoleptics with SDB may benefit from treatment with continuous positive airway pressure therapy (CPAP). The aim of this study was to examine the prevalence of SDB in narcoleptics referred to a tertiary s...

journal_title：European journal of neurology

authors： Pataka AD,Frangulyan RR,Mackay TW,Douglas NJ,Riha RL

更新日期：2012-05-01 00:00:00

abstract：:In approximately 40% of the patients, Parkinson's disease (PD) is complicated by cognitive impairment. The objective of this study was to evaluate the impact of cognitive impairment on disease severity and motor function in idiopathic PD patients. Forty-one PD patients with cognitive impairment (PD-CI) (Mini-Mental St...

journal_title：European journal of neurology

authors： Papapetropoulos S,Ellul J,Polychronopoulos P,Chroni E

更新日期：2004-05-01 00:00:00

abstract：:The aim of this study was to compare the clinically based prevalence of myasthenia gravis (MG) with the prevalence of laboratory-confirmed cases. All patients with a diagnosis of MG living in Estonia as on 1 January 1997 were asked to participate in re-examination. The criteria for laboratory-supported MG were weaknes...

journal_title：European journal of neurology

authors： Oöpik M,Puksa L,Lüüs SM,Kaasik AE,Jakobsen J

更新日期：2008-03-01 00:00:00

abstract：:Stroke is the second most common cause of mortality and a major cause of long-term disability of adults in most countries. This study was performed to determine the level of knowledge and awareness regarding risk factors and warning signs of stroke in a selected sample. This cross-sectional study was carried out in Ay...

journal_title：European journal of neurology

authors： Evci ED,Memis S,Ergin F,Beser E

更新日期：2007-05-01 00:00:00

abstract：:High socioeconomic status (SES) is generally associated with better health outcomes, but some research has linked it with an increased risk of multiple sclerosis (MS). The evidence for this association is inconsistent and has not previously been systematically reviewed. A systematic review of cohort and case-control s...

journal_title：European journal of neurology

authors： Goulden R,Ibrahim T,Wolfson C

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Up to now, there are few systematic studies in a sufficient number of patients with lesions involving the insular cortex (IC) examining whether damage of the IC is directly related to dysarthria. Thus, this is the first study applying modern voxel-lesion behaviour mapping (VLBM) aimed to examine whether the ...

journal_title：European journal of neurology

authors： Baier B,zu Eulenburg P,Glassl O,Dieterich M

更新日期：2011-12-01 00:00:00