Prevalence of migraine, tension-type headache and trigeminal neuralgia in multiple sclerosis.


BACKGROUND:Prevalence rates of headache in multiple sclerosis (MS) patients varied widely in recent studies. This study aimed to investigate the 1 year prevalence of headache in MS compared with the general population. METHODS:Population-based case-control study in Germany. RESULTS:We included 491 patients with definite MS (68% female, mean age 45.3 years, 63.7% relapsing remitting MS, mean Expanded Disability Status Scale (EDSS) 3.2, 106 treated with interferon-beta, 53 with glatiramer acetate, 271 untreated) and 447 age and gender matched controls. Headache was diagnosed with a validated questionnaire according to the International Headache Society Criteria. Headache prevalence was 56.2% (tension type headache 37.2%, migraine 24.6%). Headache prevalence rates did not differ from controls. Headache was not associated with disability or treatment. Trigeminal neuralgia was found in 6.3% of MS cases. CONCLUSION:Results suggest that headache in MS patients reflects comorbidity in most conditions.


Eur J Neurol


Putzki N,Pfriem A,Limmroth V,Yaldizli O,Tettenborn B,Diener HC,Katsarava Z




Has Abstract


2009-02-01 00:00:00














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    abstract:BACKGROUND AND PURPOSE:Transorbital sonography (TOS) has emerged as promising imaging method for the diagnosis and follow-up of acute optic neuritis (ON). Available studies report an increase in the optic nerve diameter (OND) and the optic nerve sheath diameter (ONSD) in the case of a first episode of ON in the affecte...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Schroeder C,Katsanos AH,Ayzenberg I,Schwake C,Gahlen A,Tsivgoulis G,Voumvourakis K,Gold R,Krogias C

    更新日期:2020-04-01 00:00:00

  • Homocysteine and holo-transcobalamin and the risk of dementia and Alzheimers disease: a prospective study.

    abstract:BACKGROUND:Elevated total homocysteine (tHcy) levels may be caused by vitamin B12 deficiency and are linked to Alzheimers disease (AD) in some studies, although the evidence is mixed. Another marker of vitamin B12 deficiency, holo-transcobalamin (holo-TC), has not been studied in a prospective setting. OBJECTIVE:To in...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Kivipelto M,Annerbo S,Hultdin J,Bäckman L,Viitanen M,Fratiglioni L,Lökk J

    更新日期:2009-07-01 00:00:00

  • Progressive visual loss due to a muslinoma--report of a case and review of the literature.

    abstract::Intracranial internal carotid artery (ICA) aneurysms are frequently treated either by microsurgical clipping of the aneurysm neck, by endovascular coiling of the aneurysm sac or by balloon occlusion of the parent vessel. For some broad-based aneurysms that may not be suitable for any of these options, microsurgical wr...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Berger C,Hartmann M,Wildemann B

    更新日期:2003-03-01 00:00:00

  • Acute autonomic dysfunction contralateral to acute strokes: a prospective study of 100 consecutive cases.

    abstract::Complex painful reflex syndrome is sometimes described in the chronic phase of stroke. Acute autonomic dysfunction (AAD), which is occasionally present in cases of acute stroke, has not been studied prospectively. The aim of the study was to investigate AAD on the hemibody contralateral to the lesion in the acute phas...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Diserens K,Vuadens P,Michel P,Reichhart M,Herrmann FR,Arnold P,Bogousslavsky J,Ghika J

    更新日期:2006-11-01 00:00:00

  • Action tremor in Parkinson's disease: frequency and relationship to motor and non-motor signs.

    abstract:BACKGROUND AND PURPOSE:Action tremor may occur in patients with Parkinson's disease and cause misdiagnosis with other movement disorders such as essential tremor and dystonia. Data on the frequency of action tremor in Parkinson's disease and on the relationships with other motor and non-motor signs are limited. METHOD...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Gigante AF,Bruno G,Iliceto G,Guido M,Liuzzi D,Mancino PV,De Caro MF,Livrea P,Defazio G

    更新日期:2015-02-01 00:00:00

  • Closed- and open-loop handwriting performance in patients with multiple sclerosis.

    abstract::Normal subjects use an open-loop motor control strategy in handwriting, but they are able to switch to closed-loop motor control when the demands on accuracy increase. These closed-loop handwriting movements of normal subjects resemble the inefficient movements found in writing-impaired patients. The hypothesis that s...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Schenk T,Walther EU,Mai N

    更新日期:2000-05-01 00:00:00

  • Impaired neurovascular coupling in ischaemic stroke patients with large or small vessel disease.

    abstract:BACKGROUND AND PURPOSE:There is limited data of neurovascular coupling on stroke patients, especially on comparison of different etiologies. We aim to test the hypothesis that patients with small vessel disease (SVD) are impaired on neurovascular coupling rather than stroke patient with large intracranial artery stenos...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Lin WH,Hao Q,Rosengarten B,Leung WH,Wong KS

    更新日期:2011-05-01 00:00:00

  • Trousseau's syndrome related to adenocarcinoma of the colon and cholangiocarcinoma.

    abstract::Malignancy-related thromboembolism, so-called Trousseau's syndrome, can present as acute cerebral infarction, non-bacterial thrombotic endocarditis (NBTE) and migratory thrombophlebitis. It is usually attributed to a cancer-related hypercoagulable state, chronic disseminated intravascular coagulopathy (DIC), or tumour...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Tasi SH,Juan CJ,Dai MS,Kao WY

    更新日期:2004-07-01 00:00:00

  • Charcot-Marie-Tooth type X: unusual phenotype of a novel CX32 mutation.

    abstract:BACKGROUND:X-linked Charcot-Marie-Tooth disease (CMTX), caused by mutations in the gene encoding connexin32, is the second most common form of inherited demyelinating neuropathy, next to CMT 1A, and accounts for 10-20% of all hereditary demyelinating neuropathies. AIMS OF THE STUDY:To describe clinical and electrophys...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Mazzeo A,Di Leo R,Toscano A,Muglia M,Patitucci A,Messina C,Vita G

    更新日期:2008-10-01 00:00:00

  • Electrophysiological assessment of visual function in patients with non-arteritic ischaemic optic neuropathy.

    abstract:BACKGROUND AND PURPOSE:Our study aims to evaluate retinal function and neural conduction in post-retinal visual pathways of patients with non-arteritic ischaemic optic neuropathy (NION). METHODS:Twenty patients (mean age: 63.7 +/- 5.96 year) with NION and 20 age-similar control subjects were enrolled. Simultaneous rec...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Parisi V,Gallinaro G,Ziccardi L,Coppola G

    更新日期:2008-08-01 00:00:00

  • Improvement of medical judgments by numerical training in patients with multiple sclerosis.

    abstract:BACKGROUND AND PURPOSE:People with multiple sclerosis (MS) have to face important decisions with regard to their medical treatment. The aim of this study was to evaluate whether a targeted cognitive training reduces framing effects and thus improves medical judgments. METHODS:This was a randomized, double-blind, cross...

    journal_title:European journal of neurology

    pub_type: 杂志文章,随机对照试验


    authors: Zamarian L,Delazer M,Ehling R,Pertl MT,Bsteh G,Wenter J,Glatzl S,Brenneis C,Benke T,Berger T

    更新日期:2019-01-01 00:00:00

  • The association between ankle-brachial index and asymptomatic cranial-carotid stenosis: a population-based, cross-sectional study of 5440 Han Chinese.

    abstract:BACKGROUND AND PURPOSE:Routine screening for asymptomatic cranial-carotid stenosis (ACCS) is controversial and recommendation in clinical practice is vague. The ankle-brachial index (ABI) is reported as a predictor for cardiovascular disease. However, there is a scarcity of data about the association between abnormal A...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Qiu J,Zhou Y,Yang X,Zhang Y,Li Z,Yan N,Wang Y,Ge S,Wu S,Zhao X,Wang W

    更新日期:2016-04-01 00:00:00

  • A putative polymorphic Val44Ala variation in the synphilin-1 gene is undetectable in Japanese sporadic Parkinson's disease patients.

    abstract::Recently, a novel protein-interaction partner of alpha-synuclein, designated synphilin-1, is identified as a constituent of Lewy bodies (LB) in Parkinson's disease (PD) brains. To investigate an involvement of genetic variations of synphilin-1 in development of sporadic PD, a possible single nucleotide polymorphism (S...

    journal_title:European journal of neurology

    pub_type: 临床试验,杂志文章


    authors: Satoh JI,Kuroda Y

    更新日期:2002-01-01 00:00:00

  • Current evidence for the use of botulinum toxin type A in the management of children with cerebral palsy: a systematic review.

    abstract::Management of children with cerebral palsy (CP) is the focus of considerable resources in many countries, so that evaluation of the efficacy for new and established treatments is imperative. Botulinum toxin type A (BTX-A) is a relatively new method of spasticity management in children with cerebral palsy. It has been ...

    journal_title:European journal of neurology

    pub_type: 杂志文章,评审


    authors: Boyd RN,Hays RM

    更新日期:2001-11-01 00:00:00

  • Higher early recurrence risk and potential benefit of dual antiplatelet therapy for minor stroke with watershed infarction: subgroup analysis of CHANCE.

    abstract:BACKGROUND AND PURPOSE:The aim was to explore the risk of early stroke recurrence within 3 months after watershed infarction and to investigate whether early dual antiplatelet therapy is more effective in decreasing such risk. METHODS:Patients enrolled in the Clopidogrel in High-risk Patients with Acute Non-disabling ...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Pu Y,Liu X,Wang Y,Meng X,Jing J,Zou X,Pan Y,Wang A,Zhao X,Johnston SC,Wang Y,Atchaneeyasakul K,Liebeskind DS,Liu L,CHANCE Investigators.

    更新日期:2020-05-01 00:00:00

  • Stroke following internal carotid artery occlusion - a contra-indication for intravenous thrombolysis?

    abstract::Between March 1996 and December 1997, 15 consecutive patients with carotid artery occlusion diagnosed with duplex sonography were treated with intravenous recombinant tissue plasminogen activator (rt-PA), following a protocol similar to that of the National Institute of Neurological Disorders and Stroke (NINDS) study....

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Rudolf J,Neveling M,Grond M,Schmulling S,Stenzel C,Heiss WD

    更新日期:1999-01-01 00:00:00

  • Early changes of nerve integrity in preclinical carriers of hereditary transthyretin Ala117Ser amyloidosis with polyneuropathy.

    abstract:BACKGROUND AND PURPOSE:Disease-modifying therapies provide new horizons for hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) to slow neuropathic progression. Initiating treatment at the earliest time requires biomarkers reflecting both small- and large-fiber degeneration in carriers. METHODS:This st...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Chiang MC,Yeh TY,Sung JY,Hsueh HW,Kao YH,Hsueh SJ,Chang KC,Feng FP,Lin YH,Chao CC,Hsieh ST

    更新日期:2020-12-28 00:00:00

  • Headache at onset of first-ever ischemic stroke: Clinical characteristics and predictors.

    abstract::No studies have prospectively investigated headache at onset of first-ever ischemic stroke along with a large concurrent control group. Our aims were to answer two important questions: (i) Are headaches at stroke onset causally related to the stroke, and what are their typical clinical characteristics? (ii) What etiol...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Lebedeva ER,Ushenin AV,Gurary NM,Tsypushkina TS,Gilev DV,Kislyak NV,Olesen J

    更新日期:2020-12-16 00:00:00

  • Cortical inexcitability defines an adverse clinical profile in amyotrophic lateral sclerosis.

    abstract:BACKGROUND AND PURPOSE:In amyotrophic lateral sclerosis, studies using threshold-tracking transcranial magnetic stimulation (TMS) have identified corticomotoneuronal dysfunction as a key pathogenic mechanism. Some patients, however, display no motor response at maximal TMS intensities, termed here an 'inexcitable' moto...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Dharmadasa T,Howells J,Matamala JM,Simon NG,Burke D,Vucic S,Kiernan MC

    更新日期:2021-01-01 00:00:00

  • No difference in efficacy of two different doses of intravenous immunoglobulins in MS: clinical and MRI assessment.

    abstract::We performed a double-blind, placebo-controlled study to evaluate the efficacy of low and high dose of intravenous immunoglobulins (IVIG) in relapsing/remitting (RR) multiple sclerosis (MS). Patients (n = 49) with clinical definite RR MS were randomly allocated to three groups and treated with 0.2 g/kg (n = 17) or 0.4...

    journal_title:European journal of neurology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Lewańska M,Siger-Zajdel M,Selmaj K

    更新日期:2002-11-01 00:00:00

  • Cutaneous manifestations in Moyamoya angiopathy: a review.

    abstract::Moyamoya angiopathy (MA) is a progressive cerebrovascular disease with a poorly understood pathophysiology. It is mainly characterized by progressive bilateral stenosis of the terminal intracranial part of the supraclinoid internal carotid arteries and the proximal parts of the middle and anterior cerebral arteries, a...

    journal_title:European journal of neurology

    pub_type: 杂志文章,评审


    authors: Mitri F,Bersano A,Hervé D,Kraemer M

    更新日期:2021-01-23 00:00:00

  • Intravenous thrombolysis for large vessel or distal occlusions presenting with mild stroke severity.

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    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Tsivgoulis G,Goyal N,Katsanos AH,Malhotra K,Ishfaq MF,Pandhi A,Frohler MT,Spiotta AM,Anadani M,Psychogios M,Maus V,Siddiqui A,Waqas M,Schellinger PD,Groen M,Krogias C,Richter D,Saqqur M,Garcia-Bermejo P,Mokin M,Le

    更新日期:2020-06-01 00:00:00

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    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Fourier A,Formaglio M,Kaczorowski F,Mollion H,Perret-Liaudet A,Sauvee M,Quadrio I

    更新日期:2020-07-01 00:00:00

  • Insulin-like growth factor-1 predicts cognitive functions at 2-year follow-up in early, drug-naïve Parkinson's disease.

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    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Pellecchia MT,Santangelo G,Picillo M,Pivonello R,Longo K,Pivonello C,Vitale C,Amboni M,De Rosa A,Moccia M,Erro R,De Michele G,Santoro L,Colao A,Barone P

    更新日期:2014-05-01 00:00:00

  • Evaluation of gelatinases and IL-6 in the cerebrospinal fluid of patients with optic neuritis, multiple sclerosis and other inflammatory neurological diseases.

    abstract::The activities of the metalloproteinase gelatinase B, and the presence of IL-6, an inducer of metalloproteinase inhibitors, were investigated in CSF samples of 190 patients with multiple sclerosis (MS; n = 55), optic neuritis (ON; n = 46), other inflammatory neurological diseases (OIND; n = 27) or control patients (CO...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Paemen L,Olsson T,Söderström M,van Damme J,Opdenakker G

    更新日期:1994-09-01 00:00:00

  • Prestroke antiplatelet therapy and early prognosis in stroke patients: the Dijon Stroke Registry.

    abstract:BACKGROUND AND PURPOSE:Previous antiplatelet therapy (APT) in cardiovascular prevention is common in patients with first-ever stroke. We aimed to evaluate the prognostic value of APT on early outcome in stroke patients. METHODS:All first-ever strokes from 1985 to 2011 were identified from the population-based Stroke R...

    journal_title:European journal of neurology

    pub_type: 杂志文章,多中心研究


    authors: Béjot Y,Aboa-Eboulé C,de Maistre E,Jacquin A,Troisgros O,Hervieu M,Osseby GV,Rouaud O,Giroud M

    更新日期:2013-06-01 00:00:00

  • Cognitive impairments associated with morphological changes in cortical and subcortical structures in multiple system atrophy of the cerebellar type.

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    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Lee MJ,Shin JH,Seoung JK,Lee JH,Yoon U,Oh JH,Jung DS,Kim EJ

    更新日期:2016-01-01 00:00:00

  • Cutaneous stimulation improves function of a chronic patient with cerebellar damage.

    abstract::The prognosis of cerebellar hemorrhage with brain stem compression is known to be poor, and patients who can usually survive are severely disabled with limited benefit from conventional rehabilitation. An innovative cutaneous stimulation was administered to a chronic patient (2 years after the incidence) who has sever...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Chan AS,He WJ,Cheung MC,Bai ZK,Poon WS,Sun D,Zhu XL,Chan YL

    更新日期:2003-05-01 00:00:00

  • No support for a truncated interferon-alpha 17 allele as risk factor for MS.

    abstract::Cytokines have a central role in multiple sclerosis (MS) pathogenesis and may contribute to the aetiology of MS. A polymorphism in the IFNA17 gene with an allele carrying a pre-mature stop codon has been suggested to convey a 26-fold increased risk for MS. We investigated the possible association between this polymorp...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Nyström M,Ruuth K,Lundgren E,Sundström P

    更新日期:2007-11-01 00:00:00

  • Mutational spectrum of GNAL, THAP1 and TOR1A genes in isolated dystonia: study in a population from Spain and systematic literature review.

    abstract:OBJECTIVE:We aimed to investigate the prevalence of TOR1A, GNAL and THAP1 variants as the cause of dystonia in a cohort of Spanish patients with isolated dystonia and in the literature. METHODS:A population of 2028 subjects (including 1053 patients with different subtypes of isolated dystonia and 975 healthy controls)...

    journal_title:European journal of neurology

    pub_type: 杂志文章


    authors: Gómez-Garre P,Jesús S,Periñán MT,Adarmes A,Alonso-Canovas A,Blanco-Ollero A,Buiza-Rueda D,Carrillo F,Catalán-Alonso MJ,Del Val J,Escamilla-Sevilla F,Espinosa-Rosso R,Fernández-Moreno MC,García-Moreno JM,García-Ruiz PJ,Giaco

    更新日期:2020-11-11 00:00:00