Familial aggregation of stroke amongst young patients in Lund Stroke Register.

abstract：:A comprehensive battery of neuropsychological tests sampling a wide range of cognitive functions was administrated to 36 patients with systemic lupus erythematosus (SLE), and a control group consisting of 31 patients with persistent symptoms after whiplash injury. Our results demonstrated significant group differences...

journal_title：European journal of neurology

authors： Waterloo K,Omdal R,Mellgren SI,Husby G

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to examine the association amongst remote diffusion-weighted imaging lesions (R-DWILs), imaging markers of cerebral small vessel disease (cSVD) and total cSVD burden in patients with primary intracerebral haemorrhage (ICH). METHODS:In total, 344 consecutive primary ICH ...

journal_title：European journal of neurology

authors： Xu XH,Ye XH,Li JW,Cai JS,Gao T,Zhang WJ,Zhao GH,Tong LS,Gao F

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The incidence, underlying physiopathology, features and association with lesion topography of visual hallucinations in acute stroke have scarcely been investigated. METHODS:Patients with a diagnosis of acute stroke (ischaemic or haemorrhagic) in any vascular territory, admitted within 24 h after...

journal_title：European journal of neurology

authors： Morenas-Rodríguez E,Camps-Renom P,Pérez-Cordón A,Horta-Barba A,Simón-Talero M,Cortés-Vicente E,Guisado-Alonso D,Vilaplana E,García-Sánchez C,Gironell A,Roig C,Delgado-Mederos R,Martí-Fàbregas J

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dermatomyositis (DM) with anti-nuclear matrix protein-2 (NXP-2) antibodies usually shows multifocal ischaemic lesions in muscle. Here, we aimed to investigate the microarteriopathy underlying muscle ischaemia in anti-NXP-2-positive DM. METHODS:A total of 16 patients diagnosed with anti-NXP-2-pos...

journal_title：European journal of neurology

authors： Liu Y,Zheng Y,Gang Q,Xie Z,Jin Y,Zhang X,Deng X,Hao H,Gao F,Zhang Z,Xiong H,Zhang W,Wang Z,Yuan Y

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CACNA1A encodes the α1 subunit of the neuronal calcium channel P/Q. CACNA1A mutations underlie three allelic disorders: familial hemiplegic migraine type 1 (FHM1), episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6). A clear-cut genotype-phenotype correlation is often lacking si...

journal_title：European journal of neurology

authors： Indelicato E,Nachbauer W,Karner E,Eigentler A,Wagner M,Unterberger I,Poewe W,Delazer M,Boesch S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Frontotemporal dementia (FTD) is a degenerative disorder characterized, in its frontal variant, by psychiatric onset, deficits in executive functions and sparing of memory and visuo-spatial abilities. Studies on visuo-spatial abilities in FTD and Alzheimer's disease (AD) have mainly focused on co...

journal_title：European journal of neurology

authors： Gasparini M,Masciarelli G,Vanacore N,Ottaviani D,Salati E,Talarico G,Lenzi GL,Bruno G

更新日期：2008-06-01 00:00:00

abstract：:This study is aimed at assessing the prevalence and features of psychotic symptoms in a sample of 180 patients with Alzheimer's disease (AD). Sixty-four patients (35.5% of the sample) showed one or more psychotic symptoms. The presence of these symptoms correlated with the severity of the patients' cognitive impairmen...

journal_title：European journal of neurology

authors： Sala SD,Francescani A,Muggia S,Spinnler H

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim was to explore the risk of early stroke recurrence within 3 months after watershed infarction and to investigate whether early dual antiplatelet therapy is more effective in decreasing such risk. METHODS:Patients enrolled in the Clopidogrel in High-risk Patients with Acute Non-disabling ...

journal_title：European journal of neurology

authors： Pu Y,Liu X,Wang Y,Meng X,Jing J,Zou X,Pan Y,Wang A,Zhao X,Johnston SC,Wang Y,Atchaneeyasakul K,Liebeskind DS,Liu L,CHANCE Investigators.

更新日期：2020-05-01 00:00:00

abstract：:Neurosarcoidosis occurs in 5-15% of sarcoidosis cases. Approximately 50% of patients with neurosarcoidosis present with a neurological disease at the time sarcoidosis is first diagnosed. Spinal sarcoidosis is rare. We report the case of a 61-year-old man with a highly aspecific intramedullary lesion as the first manif...

journal_title：European journal of neurology

authors： Caneparo D,Lucetti C,Nuti A,Cipriani G,Tessa C,Fazzi P,Bonuccelli U

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:  Therapy for multiple sclerosis (MS) has a partial efficacy, and a significant proportion of treated patients will develop a suboptimal response with first-line disease-modifying drugs (DMD). Therapy switch in patients with MS can be a strategy after a treatment failure. We studied the change in clinical ac...

journal_title：European journal of neurology

authors： Río J,Tintoré M,Sastre-Garriga J,Nos C,Castilló J,Tur C,Comabella M,Montalban X

更新日期：2012-06-01 00:00:00

abstract：:We describe a patient who, three years after the onset of an olivopontocerebellar atrophy, developed a right cerebral tumour. The cerebellar symptomatology also included, as in other cerebellar patients previously described, a peripheral dysgraphia. Because this deficit of writing is generally reported in patients wit...

journal_title：European journal of neurology

authors： Silveri MC,Misciagna S,Laudisio A,Colosimo C

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia occurs in up to 50% of all patients with acute stroke. There is debate regarding which is the most effective screening tool in identifying aspiration in patients with acute stroke. We assessed the accuracy of the Sapienza Global Bedside Evaluation of Swallowing after Stroke (GLOBE-3S), ...

journal_title：European journal of neurology

authors： Toscano M,Viganò A,Rea A,Verzina A,Sasso D'Elia T,Puledda F,Longo L,Mancini V,Ruggiero M,Jannini TB,Giuliani G,Albino F,Altieri M,Vicenzini E,Fattapposta F,Pauri F,Giacomini P,Ruoppolo G,Di Piero V

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Brain atrophy is related to clinical deterioration in multiple sclerosis (MS) but its association with intrathecal markers of inflammation or neurodegeneration is unclear. Our aim was to investigate whether cerebrospinal fluid (CSF) markers of inflammation or neurodegeneration are associated with...

journal_title：European journal of neurology

authors： Mellergård J,Tisell A,Blystad I,Grönqvist A,Blennow K,Olsson B,Dahle C,Vrethem M,Lundberg P,Ernerudh J

更新日期：2017-01-01 00:00:00

abstract：:Mirror movements (MM), involuntary movements of homologous muscles opposite to unilateral limb activity, decrease in the course of motor development, but may reappear in adults after brain damage. To better characterize this type of acquired MM, grip forces of 36 healthy subjects and 35 patients suffering from focal b...

journal_title：European journal of neurology

authors： Uttner I,Mai N,Esslinger O,Danek A

更新日期：2005-12-01 00:00:00

abstract：:We performed a placebo-controlled cross-over trial of riluzole (100 mg b.i.d.) in 10 patients with probable multiple system atrophy (MSA) administering riluzole and placebo for 4 weeks each with a 4-week washout period. Outcome measures evaluated short-term anti-Parkinsonian effects using the Unified Parkinson's Disea...

journal_title：European journal of neurology

authors： Seppi K,Peralta C,Diem-Zangerl A,Puschban Z,Mueller J,Poewe W,Wenning GK

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In amyotrophic lateral sclerosis, studies using threshold-tracking transcranial magnetic stimulation (TMS) have identified corticomotoneuronal dysfunction as a key pathogenic mechanism. Some patients, however, display no motor response at maximal TMS intensities, termed here an 'inexcitable' moto...

journal_title：European journal of neurology

authors： Dharmadasa T,Howells J,Matamala JM,Simon NG,Burke D,Vucic S,Kiernan MC

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is well established that patient-related constitutional features predispose to focal peripheral neuropathies. Some of these risk factors were investigated in common focal neuropathies encountered in patients referred for electromyography. METHODS:Gender, age, height and body mass index (BMI) ...

journal_title：European journal of neurology

authors： Martínez-Aparicio C,Jääskeläinen SK,Puksa L,Reche-Lorite F,Torné-Poyatos P,Paniagua Soto J,Falck B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We investigated the effectiveness of intravenous thrombolysis (IVT) in acute ischaemic stroke (AIS) patients with large vessel or distal occlusions and mild neurological deficits, defined as National Institutes of Health Stroke Scale scores < 6 points. METHODS:The primary efficacy outcome was 3-...

journal_title：European journal of neurology

authors： Tsivgoulis G,Goyal N,Katsanos AH,Malhotra K,Ishfaq MF,Pandhi A,Frohler MT,Spiotta AM,Anadani M,Psychogios M,Maus V,Siddiqui A,Waqas M,Schellinger PD,Groen M,Krogias C,Richter D,Saqqur M,Garcia-Bermejo P,Mokin M,Le

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our study aims to evaluate retinal function and neural conduction in post-retinal visual pathways of patients with non-arteritic ischaemic optic neuropathy (NION). METHODS:Twenty patients (mean age: 63.7 +/- 5.96 year) with NION and 20 age-similar control subjects were enrolled. Simultaneous rec...

journal_title：European journal of neurology

authors： Parisi V,Gallinaro G,Ziccardi L,Coppola G

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lower urinary tract symptoms (LUTS) including frequent urination, nocturia and urge urinary incontinence negatively impact quality of life. This project aimed at characterizing the prevalence and severity of urinary incontinence in multiple sclerosis (MS) patients and its association with demogra...

journal_title：European journal of neurology

authors： Zecca C,Riccitelli GC,Disanto G,Singh A,Digesu GA,Panicari L,Puccini F,Mattioli M,Tubaro A,Gobbi C

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative stress plays an important role in acute ischaemic stroke. However, the association of oxidative lipoprotein markers, including oxidized low-density lipoprotein (oxLDL), oxLDL:high-density lipoprotein (HDL) and oxLDL:low-density lipoprotein (LDL), with functional outcome of minor stroke ...

journal_title：European journal of neurology

authors： Wang A,Zhang X,Li S,Zhao X,Liu L,Johnston SC,Meng X,Lin J,Zuo Y,Li H,Wang Y,Wang Y,CHANCE Study Group.

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Parkinson´s disease (PD) has a large phenotypic variability, which may, at least partly, be genetically driven including alterations of gene products. Candidates might not only be proteins associated with disease risk but also pathways that play a role in aging. OBJECTIVE:To evaluate phenotype-modifying eff...

journal_title：European journal of neurology

authors： Zimmermann M,Köhler L,Kovarova M,Lerche S,Schulte C,Wurster I,Machetanz G,Deuschle C,Hauser AK,Gasser T,Berg D,Schleicher E,Maetzler W,Brockmann K

更新日期：2021-01-15 00:00:00

abstract：BACKGROUND AND PURPOSE:Our objective was to study the association between serum levels of anti Epstein-Barr virus nuclear antigen 1 (EBNA-1) antibody and 25-hydroxyvitamin D (25(OH)D) in a prospective cohort of patients with relapsing-remitting multiple sclerosis. METHOD:The study comprised 90 patients with relapsing-...

journal_title：European journal of neurology

authors： Wergeland S,Myhr KM,Løken-Amsrud KI,Beiske AG,Bjerve KS,Hovdal H,Midgard R,Kvistad SS,Holmøy T,Riise T,Torkildsen Ø

更新日期：2016-06-01 00:00:00

abstract：:To evaluate prevalence of use and prescribing patterns of antiepileptic drugs (AEDs) in Italian general practice. Primary care data were obtained from the Health Search Database, a longitudinal observational database implemented by the Italian College of General Practitioners (GPs). We selected 465 061 subjects regist...

journal_title：European journal of neurology

authors： Savica R,Beghi E,Mazzaglia G,Innocenti F,Brignoli O,Cricelli C,Caputi AP,Musolino R,Spina E,Trifirò G

更新日期：2007-12-01 00:00:00

abstract：INTRODUCTION:Little is known about neurological training curricula in Europe. A joint approach by the European Federation of Neurological Societies (EFNS), the Union of European Medical Specialists/European Board of Neurology and the European Association of Young Neurologist and Trainees was established to explore the ...

journal_title：European journal of neurology

authors： Struhal W,Sellner J,Lisnic V,Vécsei L,Müller E,Grisold W

更新日期：2011-04-01 00:00:00

abstract：:Hereditary spastic paraparesis (HSP) is a heterogeneous group of neurodegenerative disorders with progressive lower limb spasticity, categorized into pure (p-HSP) and complicated forms (c-HSP). The purpose of this study was to evaluate if brain volumes in HSP were altered compared with a control population. Brain volu...

journal_title：European journal of neurology

authors： Kassubek J,Sperfeld AD,Baumgartner A,Huppertz HJ,Riecker A,Juengling FD

更新日期：2006-08-01 00:00:00

abstract：:The genetic underpinnings of frontotemporal dementia (FTD), a rare yet early onset disorder still remains elusive. As FTD is characterized by a serotonergic deficit in the frontal lobe, and as some symptoms of FTD resemble conditions of monoamino oxidase A (MAO-A) deficiency, MAO-A is an attractive candidate gene for ...

journal_title：European journal of neurology

authors： Reif A,Scarpini E,Venturelli E,Töpner T,Fenoglio C,Lesch KP,Galimberti D

更新日期：2008-06-01 00:00:00

abstract：:The present review of epidemiologic studies on migraine and headache in Europe is part of a larger initiative by the European Brain Council to estimate the costs incurred because of brain disorders. Summarizing the data on 1-year prevalence, the proportion of adults in Europe reporting headache was 51%, migraine 14%, ...

journal_title：European journal of neurology

authors： Stovner LJ,Zwart JA,Hagen K,Terwindt GM,Pascual J

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CACNA1S encodes Cav 1.1, a voltage sensor for muscle excitation-contraction coupling, which activates the ryanodine receptor 1 (RYR1) leading to calcium release from the sarcoplasmic reticulum. CACNA1S mutations cause hypokalemic periodic paralysis, malignant hyperthermia and congenital myopathy....

journal_title：European journal of neurology

authors： Anandan C,Cipriani MA,Laughlin RS,Niu Z,Milone M

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Detection of occult atrial fibrillation (AF) is crucial for optimal secondary prevention in stroke patients. The AF detection rate was determined by implantable cardiac monitor (ICM) and compared to the prediction rate of the probability of incident AF by software based analysis of a continuously...

journal_title：European journal of neurology

authors： Reinke F,Bettin M,Ross LS,Kochhäuser S,Kleffner I,Ritter M,Minnerup J,Dechering D,Eckardt L,Dittrich R

更新日期：2018-04-01 00:00:00