Abstract:
:Neurosarcoidosis occurs in 5-15% of sarcoidosis cases. Approximately 50% of patients with neurosarcoidosis present with a neurological disease at the time sarcoidosis is first diagnosed. Spinal sarcoidosis is rare. We report the case of a 61-year-old man with a highly aspecific intramedullary lesion as the first manifestation of sarcoidosis. One year after the onset of neurological symptoms, the high levels of angiotensin-converting enzyme and the results of a total body gallium scan and bronchoalveolar lavage supported the diagnosis of sarcoidosis. Isolated single reports indicate that spinal neurosarcoidosis may be the initial manifestation of sarcoidosis. In our case, magnetic resonance imaging of the dorsal spine showed a largely aspecific lesion. Neurosarcoidosis should be considered in the differential diagnosis of intramedullary cord lesion with leptomeningeal enhancement; a systematic search for evidence of sarcoidosis should be mandatory in all cases for a correct diagnosis and early treatment.
journal_name
Eur J Neuroljournal_title
European journal of neurologyauthors
Caneparo D,Lucetti C,Nuti A,Cipriani G,Tessa C,Fazzi P,Bonuccelli Udoi
10.1111/j.1468-1331.2006.01527.xsubject
Has Abstractpub_date
2007-03-01 00:00:00pages
346-9issue
3eissn
1351-5101issn
1468-1331pii
ENE1527journal_volume
14pub_type
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