Prodrome in relapsing-remitting and primary progressive multiple sclerosis.

abstract：BACKGROUND AND PURPOSE:The role of cardiovascular risk factors in the pathogenesis of cognitive impairment and dementia remains still unclear. We examined the impact of cardiovascular risk factors on cognitive function in a large longitudinal population study. METHODS:Subjects were 5033 stroke-free men and women who p...

journal_title：European journal of neurology

authors： Arntzen KA,Schirmer H,Wilsgaard T,Mathiesen EB

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of lifestyle and dietary habits and antecedent events has not been clearly identified in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). METHODS:Information was collected about modifiable environmental factors and antecedent infections and vaccinations in patients with...

journal_title：European journal of neurology

authors： Doneddu PE,Bianchi E,Cocito D,Manganelli F,Fazio R,Filosto M,Mazzeo A,Cosentino G,Cortese A,Jann S,Clerici AM,Antonini G,Siciliano G,Luigetti M,Marfia GA,Briani C,Lauria G,Rosso T,Cavaletti G,Carpo M,Benedetti L,

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Associations with multiple sclerosis (MS) of living conditions in childhood and characteristics in adolescence including physical fitness, cognitive function and psychological stress resilience were investigated. METHODS:A cohort of male Swedish residents born 1952-1956 who were included in the ...

journal_title：European journal of neurology

authors： Gunnarsson M,Udumyan R,Bahmanyar S,Nilsagård Y,Montgomery S

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our study aims to evaluate retinal function and neural conduction in post-retinal visual pathways of patients with non-arteritic ischaemic optic neuropathy (NION). METHODS:Twenty patients (mean age: 63.7 +/- 5.96 year) with NION and 20 age-similar control subjects were enrolled. Simultaneous rec...

journal_title：European journal of neurology

authors： Parisi V,Gallinaro G,Ziccardi L,Coppola G

更新日期：2008-08-01 00:00:00

abstract：:In recent years, evidence has emerged for a bidirectional relationship between sleep and neurological and psychiatric disorders. First, sleep-wake disorders (SWDs) are very common and may be the first/main manifestation of underlying neurological and psychiatric disorders. Secondly, SWDs may represent an independent r...

journal_title：European journal of neurology

authors： Bassetti CL,Ferini-Strambi L,Brown S,Adamantidis A,Benedetti F,Bruni O,Cajochen C,Dolenc-Groselj L,Ferri R,Gais S,Huber R,Khatami R,Lammers GJ,Luppi PH,Manconi M,Nissen C,Nobili L,Peigneux P,Pollmächer T,Randerath W

更新日期：2015-10-01 00:00:00

abstract：:Normal subjects use an open-loop motor control strategy in handwriting, but they are able to switch to closed-loop motor control when the demands on accuracy increase. These closed-loop handwriting movements of normal subjects resemble the inefficient movements found in writing-impaired patients. The hypothesis that s...

journal_title：European journal of neurology

authors： Schenk T,Walther EU,Mai N

更新日期：2000-05-01 00:00:00

abstract：:Autoantibodies in patients with paraneoplastic neurological syndromes (PNS) have been reported to be predominantly IgG1 and IgG3 isotypes. However, no data are available about the IgG subclass distribution of the total serum IgG in these patients. Therefore, we investigated the IgG subclass distribution (given as perc...

journal_title：European journal of neurology

authors： Blaes F,Klotz M,Funke D,Strittmatter M,Kraus J,Kaps M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Benign paroxysmal positional vertigo (BPPV) is a frequently encountered condition that can severely affect the quality of life. In this study, we aimed to assess the possible relations between serum uric acid (SUA) levels and BPPV. METHODS:Fifty patients with BPPV, and 40 age- and sex-matched co...

journal_title：European journal of neurology

authors： Celikbilek A,Gencer ZK,Saydam L,Zararsiz G,Tanik N,Ozkiris M

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is well established that patient-related constitutional features predispose to focal peripheral neuropathies. Some of these risk factors were investigated in common focal neuropathies encountered in patients referred for electromyography. METHODS:Gender, age, height and body mass index (BMI) ...

journal_title：European journal of neurology

authors： Martínez-Aparicio C,Jääskeläinen SK,Puksa L,Reche-Lorite F,Torné-Poyatos P,Paniagua Soto J,Falck B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although there is growing and convincing evidence that socially deprived patients are at higher risk of stroke and worse outcomes, it remains controversial whether or not they suffer more severe stroke. This study aimed to evaluate the influence of social deprivation on initial clinical severity ...

journal_title：European journal of neurology

authors： Béjot Y,Guilloteau A,Joux J,Lannuzel A,Mimeau E,Mislin-Tritsch C,Fournel I,Bonithon-Kopp C,INDIA Study Group.

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dermatomyositis (DM) with anti-nuclear matrix protein-2 (NXP-2) antibodies usually shows multifocal ischaemic lesions in muscle. Here, we aimed to investigate the microarteriopathy underlying muscle ischaemia in anti-NXP-2-positive DM. METHODS:A total of 16 patients diagnosed with anti-NXP-2-pos...

journal_title：European journal of neurology

authors： Liu Y,Zheng Y,Gang Q,Xie Z,Jin Y,Zhang X,Deng X,Hao H,Gao F,Zhang Z,Xiong H,Zhang W,Wang Z,Yuan Y

更新日期：2020-03-01 00:00:00

abstract：:Intracranial internal carotid artery (ICA) aneurysms are frequently treated either by microsurgical clipping of the aneurysm neck, by endovascular coiling of the aneurysm sac or by balloon occlusion of the parent vessel. For some broad-based aneurysms that may not be suitable for any of these options, microsurgical wr...

journal_title：European journal of neurology

authors： Berger C,Hartmann M,Wildemann B

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Predicting the course of behavioural variant frontotemporal dementia (bvFTD) remains a major clinical challenge. This study aimed to identify factors that predict survival and clinical progression in bvFTD. METHODS:Consecutive patients with clinically probable bvFTD were prospectively followed u...

journal_title：European journal of neurology

authors： Agarwal S,Ahmed RM,D'Mello M,Foxe D,Kaizik C,Kiernan MC,Halliday GM,Piguet O,Hodges JR

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The presence of the apolipoprotein E (ApoE) 4 genotype is associated with an earlier age of onset for Alzheimer's disease (AD) and several other neurodegenerative disorders. The objective of this study was to investigate the effect of ApoE genotypes on the clinical course of amyotrophic lateral sclerosis (AL...

journal_title：European journal of neurology

authors： Jawaid A,Poon M,Strutt AM,Rice LK,McDowell EJ,Salamone AR,Qureshi SU,Simpson E,Appel SH,York MK,Schulz PE

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Patients with Parkinson's disease (PD) and chronically treated with L-DOPA exhibit, in a percentage of 10-30%, supra-physiological levels of plasma total homocysteinemia (tHcy). In this study, we have investigated, in a group of hyper-homocysteinemic PD patients, the time of hyper-tHcy recurrence after disco...

journal_title：European journal of neurology

authors： Belcastro V,Pierguidi L,Castrioto A,Menichetti C,Gorgone G,Ientile R,Pisani F,Rossi A,Calabresi P,Tambasco N

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS)-related genes and mutations have been increasingly discovered recently and an improved understanding of genotype-phenotype relationships may help to predict the disease course and refine genetic diagnosis. METHODS:We collected clinical data and blood samples f...

journal_title：European journal of neurology

authors： Chen W,Xie Y,Zheng M,Lin J,Huang P,Pei Z,Yao X

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hereditary sensory and autonomic neuropathies (HSANs) are a group of clinically and genetically heterogeneous neurological disorders characterized by sensory dysfunctions. Here, 21 affected Chinese families are reported, including 19 with congenital insensitivity to pain with anhidrosis (CIPA; na...

journal_title：European journal of neurology

authors： Zhao F,Mao B,Geng X,Ren X,Wang Y,Guan Y,Li S,Li L,Zhang S,You Y,Cao Y,Yang T,Zhao X

更新日期：2020-08-01 00:00:00

abstract：:The authors performed neurological, visual evoked potentials (VEP) and electroneurography (ENG) examinations on three groups of workers with occupational exposure to mercury vapors (Hg(0)), and on a control group. The exposure of dental professionals (n = 36) was mild, that of chloralkali plant workers (n = 36) was in...

journal_title：European journal of neurology

authors： Urban P,Lukás E,Nerudová J,Cábelková Z,Cikrt M

更新日期：1999-09-01 00:00:00

abstract：:The incidence of the neuropathological lesions and the severity of the clinical symptoms in multiple sclerosis (MS) are correlated with the amount of the transferred autoreactive T cells. The balance between the T helper 1 (Th1) and T helper 2 (Th2) cytokine phenotypes may affect the activity of the disease in MS pati...

journal_title：European journal of neurology

authors： Ersoy E,Kuş CN,Sener U,Coker I,Zorlu Y

更新日期：2005-03-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIg) is an efficacious treatment for immune-mediated neuropathies like Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating neuropathy (CIDP), and multifocal motor neuropathy (MMN). In the pathogenesis of immune-mediated neuropathies chemokines and their receptors play a cruci...

journal_title：European journal of neurology

authors： Trebst C,Brunhorn K,Lindner M,Windhagen A,Stangel M

更新日期：2006-12-01 00:00:00

abstract：:We studied specific aspects of speed performance in neuropsychological tests and functional and vocational long-term outcome among moderate or severe traumatic brain injury (TBI) patients admitted to a rehabilitation programme. A group of 140 patients with mild, moderate or severe TBI was followed up for a minimum of ...

journal_title：European journal of neurology

authors： Asikainen I,Nybo T,Muller K,Sarna S,Kaste M

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Educating the public to screen for vascular risk factors and have them treated is a major public health issue. We assessed the vascular risk factor awareness and frequency of treatment in a cohort of patients with cerebral ischaemia. METHODS:Data on awareness and pharmacological treatment of vas...

journal_title：European journal of neurology

authors： Nolte CH,Jungehulsing GJ,Rossnagel K,Roll S,Haeusler KG,Reich A,Willich SN,Villringer A,Muller-Nordhorn J

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cognitive impairment is common in Parkinson's disease (PD), even in the early stages. We aimed to assess the relationship between insulin-like growth factor-1 (IGF-1) and cognitive functions in early, drug-naïve patients with PD. METHODS:Serum IGF-1 was measured in 65 early, drug-naïve patients ...

journal_title：European journal of neurology

authors： Pellecchia MT,Santangelo G,Picillo M,Pivonello R,Longo K,Pivonello C,Vitale C,Amboni M,De Rosa A,Moccia M,Erro R,De Michele G,Santoro L,Colao A,Barone P

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autoantibodies (abs) to glutamic acid decarboxylase (GAD) and to voltage-gated potassium channels (VGKC) induce distinct courses of limbic encephalitis, related to MRI findings, seizure outcome and cognition. METHODS:A detailed analysis of the cognitive course of the two forms is presented, span...

journal_title：European journal of neurology

authors： Frisch C,Malter MP,Elger CE,Helmstaedter C

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim was to study the prevalence of epilepsy in a hospital-based systemic lupus erythematosus (SLE) cohort and to investigate the relationship between epilepsy and other manifestations of neuropsychiatric SLE (NPSLE). METHODS:The study population consisted of 440 SLE patients recruited from 1...

journal_title：European journal of neurology

authors： Hopia L,Andersson M,Svenungsson E,Khademi M,Piehl F,Tomson T

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neuropsychiatric symptoms are commonly observed in neurodegenerative diseases. No biomarker is currently available to diagnose psychiatric conditions. As a consequence, the distinction between psychiatric and neurodegenerative disorders can be challenging in daily practice. METHODS:This retrospe...

journal_title：European journal of neurology

authors： Fourier A,Formaglio M,Kaczorowski F,Mollion H,Perret-Liaudet A,Sauvee M,Quadrio I

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Limited information is available about the impact of seizures on stroke outcome, health care delivery and resource utilization. OBJECTIVE:To determine whether the presence of seizures after stroke increases disability, mortality and health care utilization (length of hospital stay, ICU admission, consults...

journal_title：European journal of neurology

authors： Burneo JG,Fang J,Saposnik G,Investigators of the Registry of the Canadian Stroke Network.

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Magnetic resonance diffusivity indices have been repeatedly proposed as biomarkers of neurodegeneration in amyotrophic lateral sclerosis (ALS), but no consensus exists as to which diffusivity parameter is the most sensitive to identify early degenerative changes. Despite numerous studies, surpris...

journal_title：European journal of neurology

authors： Schuster C,Elamin M,Hardiman O,Bede P

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multiple sclerosis (MS) patients are often emotionally disturbed. We investigated anger in these patients in relation to demographic, clinical, and mood characteristics. PATIENTS AND METHODS:About 195 cognitively unimpaired MS patients (150 relapsing-remitting and 45 progressive) were evaluated ...

journal_title：European journal of neurology

authors： Nocentini U,Tedeschi G,Migliaccio R,Dinacci D,Lavorgna L,Bonavita S,Bresciamorra V,Comanducci G,Coniglio G,Livrea P,Mannu R,Orefice G,Paciello M,Patti F,Quattrone A,Salemi G,Savettieri G,Simone IL,Valentino P,Zappia

更新日期：2009-12-01 00:00:00

abstract：:Malignancy-related thromboembolism, so-called Trousseau's syndrome, can present as acute cerebral infarction, non-bacterial thrombotic endocarditis (NBTE) and migratory thrombophlebitis. It is usually attributed to a cancer-related hypercoagulable state, chronic disseminated intravascular coagulopathy (DIC), or tumour...

journal_title：European journal of neurology

authors： Tasi SH,Juan CJ,Dai MS,Kao WY

更新日期：2004-07-01 00:00:00