Impact of cardiovascular risk factors on cognitive function: the Tromsø study.

abstract：:The presence of white matter lesions (WML) is an important prognostic factor for the development of stroke. Plasma total homocysteine (tHcy), which increases with diabetes, has been flagged as a novel predictor for cerebrovascular events. We tested the hypothesis that the presence of WML correlates with tHcy and insul...

journal_title：European journal of neurology

authors： Shimomura T,Anan F,Umeno Y,Eshima N,Saikawa T,Yoshimatsu H,Fujiki M,Kobayashi H

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:People with multiple sclerosis (MS) have to face important decisions with regard to their medical treatment. The aim of this study was to evaluate whether a targeted cognitive training reduces framing effects and thus improves medical judgments. METHODS:This was a randomized, double-blind, cross...

journal_title：European journal of neurology

authors： Zamarian L,Delazer M,Ehling R,Pertl MT,Bsteh G,Wenter J,Glatzl S,Brenneis C,Benke T,Berger T

更新日期：2019-01-01 00:00:00

abstract：:Management of children with cerebral palsy (CP) is the focus of considerable resources in many countries, so that evaluation of the efficacy for new and established treatments is imperative. Botulinum toxin type A (BTX-A) is a relatively new method of spasticity management in children with cerebral palsy. It has been ...

journal_title：European journal of neurology

authors： Boyd RN,Hays RM

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multiple sclerosis (MS) patients discontinuing natalizumab are at risk of rebound of disease activity. METHODS:In the present multi-center, open-label, non-randomized, prospective, pilot study, we tested whether treatment with glatiramer acetate (GA) is safe and effective after natalizumab in MS...

journal_title：European journal of neurology

authors： Rossi S,Motta C,Studer V,De Chiara V,Barbieri F,Monteleone F,Fornasiero A,Coarelli G,Bernardi G,Cutter G,Stüve O,Salvetti M,Centonze D

更新日期：2013-01-01 00:00:00

abstract：BACKGROUNDAND PURPOSE:The purpose was to estimate the risk of epilepsy in a cohort of young individuals with celiac disease (CD) compared to that of matched references. METHODS:The cohort consisted of 213 635 individuals born during 1989-2011 and residing in Friuli-Venezia Giulia (Italy). 1215 individuals affected by ...

journal_title：European journal of neurology

authors： Canova C,Ludvigsson J,Barbiellini Amidei C,Zanier L,Zingone F

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The guidelines for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) therapy suggest to use immunoglobulins (IVIg) and steroid as first-line therapies. Patients who do not respond to one of the two drugs should be switched to the other drug. We collected therapeutic outcome data in...

journal_title：European journal of neurology

authors： Cocito D,Paolasso I,Antonini G,Benedetti L,Briani C,Comi C,Fazio R,Jann S,Matà S,Mazzeo A,Sabatelli M,Nobile-Orazio E,Italian Network for CIDP Register.

更新日期：2010-02-01 00:00:00

abstract：:This paper describes a technique for treatment of relative sialorrhoea by injection of botulinum toxin type A. It includes the rationale for treatment, a description of the regional anatomy, the physiological basis for treatment and the applied pharmacology of the drug. Included also is a case report which is intended...

journal_title：European journal of neurology

authors： Glickman S,Deaney CN

更新日期：2001-11-01 00:00:00

abstract：:Although the value of magnetic resonance imaging (MRI) for diagnosis/differential diagnosis of patients with clinically isolated syndromes suggestive of multiple sclerosis (MS) is widely accepted, adoption of MRI into clinical practice to monitor disease evolution remains a work in progress. However, an accumulating b...

journal_title：European journal of neurology

authors： Oreja-Guevara C,ParadigMS Group.

更新日期：2015-10-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic and potentially highly disabling disorder with considerable social impact and economic consequences. It is the major cause of non-traumatic disability in young adults. The social costs associated with MS are high because of its long duration, the early loss of productivity, the nee...

journal_title：European journal of neurology

authors： Pugliatti M,Rosati G,Carton H,Riise T,Drulovic J,Vécsei L,Milanov I

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is an urgent need for early predictive markers for the course of disease in prodromal α-synucleinopathies such as idiopathic rapid eye movement (REM) sleep behaviour disorder. Autonomic cardiac/vascular dysfunction is a prominent feature in advanced α-synucleinopathies, but its diagnostic v...

journal_title：European journal of neurology

authors： Dahms C,Guenther A,Schwab M,Schultze T,Nowack S,Hoyer D,Ehrhardt J,Witte OW,Mayer G,Rupprecht S

更新日期：2016-05-01 00:00:00

abstract：:Stroke is the second most common cause of mortality and a major cause of long-term disability of adults in most countries. This study was performed to determine the level of knowledge and awareness regarding risk factors and warning signs of stroke in a selected sample. This cross-sectional study was carried out in Ay...

journal_title：European journal of neurology

authors： Evci ED,Memis S,Ergin F,Beser E

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To examine the frequencies and clinical characteristics of fallers and non-fallers at different stages of Parkinson's disease (PD). METHODS:The sample consisted of 232 patients in an unselected cross-sectional cohort of patients with PD, 207 newly diagnosed and drug naive patients and 175 contro...

journal_title：European journal of neurology

authors： Hiorth YH,Lode K,Larsen JP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Amyotrophic lateral sclerosis (ALS) is classically assumed to be a neurodegenerative disorder. Inflammation has been observed in CNS tissue in ALS patients. We investigated the expression and prognostic relevance of proinflammatory chemokines in ALS. METHODS:We analyzed nine chemokines, eotaxin,...

journal_title：European journal of neurology

authors： Kuhle J,Lindberg RL,Regeniter A,Mehling M,Steck AJ,Kappos L,Czaplinski A

更新日期：2009-06-01 00:00:00

abstract：:Studies of the cephalic vascular system have markedly contributed towards an understanding of the mechanisms of migraine pain. Whereas cerebral blood flow changes, and thereby changes in the arterioles, correlate poorly with migraine headache, abnormal regulation of the large cranial arteries seems to play a significa...

journal_title：European journal of neurology

authors： Thomsen LL

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Headache has been associated with various lifestyle and psychosocial factors, one of which is smoking. The aim of the present study was to investigate whether the association between smoking intensity and headache is likely to be causal. METHOD:A total of 58 316 participants from the Nord-Trønde...

journal_title：European journal of neurology

authors： Johnsen MB,Winsvold BS,Børte S,Vie GÅ,Pedersen LM,Storheim K,Skorpen F,Hagen K,Bjørngaard JH,Åsvold BO,Zwart JA

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The National Institute for Health and Care Excellence (NICE) in the UK recommends the use of OnabotulinumtoxinA (BoNTA, Botox® ) in the management of chronic migraine (CM) following specific guidelines within the National Health Service. In view of the lack of data on the efficacy of this therapy...

journal_title：European journal of neurology

authors： Andreou AP,Trimboli M,Al-Kaisy A,Murphy M,Palmisani S,Fenech C,Smith T,Lambru G

更新日期：2018-08-01 00:00:00

abstract：:In recent years, a number of potential new therapeutic indications of botulinum toxin injections have emerged, amongst which sialorrhea has attracted considerable attention. Based on open-label and controlled studies, botulinum toxin can be used to improve sialorrhea in patients with Parkinson's disease, parkinsonian ...

journal_title：European journal of neurology

authors： Tan EK

更新日期：2006-02-01 00:00:00

abstract：:Recent studies in aged, neurologically unimpaired subjects have pointed to a specific induction site of the pathological process of Parkinson's disease (PD) in the region of the dorsal glossopharyngeus-vagus complex as well as in the anterior olfactory nucleus. From the lower brainstem, the disease process would then ...

journal_title：European journal of neurology

authors： Probst A,Bloch A,Tolnay M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Improved biomarkers are needed to facilitate clinical decision-making and as surrogate endpoints in clinical trials in multiple sclerosis (MS). We assessed whether neurodegenerative and neuroinflammatory markers in cerebrospinal fluid (CSF) at initial sampling could predict disease activity durin...

journal_title：European journal of neurology

authors： Håkansson I,Tisell A,Cassel P,Blennow K,Zetterberg H,Lundberg P,Dahle C,Vrethem M,Ernerudh J

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately 9000 people in the UK are affected by Huntington's disease (HD). People with HD require ongoing health and social care support. There is a knowledge gap about costs of health and social care use associated with HD in the UK. This paper estimates the economic cost in the UK. METHODS...

journal_title：European journal of neurology

authors： Jones C,Busse M,Quinn L,Dawes H,Drew C,Kelson M,Hood K,Rosser A,Edwards RT

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Migraine pathophysiology involves a complex interplay of processes wherein the hormonal, neurotransmitter and inflammatory pathways interact to influence the migraine phenotype. However, all studies pertaining to the role of genetic variants in migraine have been restricted to a specific pathway ...

journal_title：European journal of neurology

authors： Ghosh J,Pradhan S,Mittal B

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non-motor symptoms, including cognitive deficits. Several magnetic resonance imaging approaches have been applied to investigate brain atrophy in PD. The aim of this study was to detect early structural cortical a...

journal_title：European journal of neurology

authors： Danti S,Toschi N,Diciotti S,Tessa C,Poletti M,Del Dotto P,Lucetti C

更新日期：2015-12-01 00:00:00

abstract：:We report a long-term outcome of motor function in a patient with adult-onset adrenoleukodystrophy after bone marrow transplantation (BMT). Clinically motor function gradually improved and became almost normal in 2 years after BMT. Serial transcranial magnetic stimulation showed gradual improvement of central motor co...

journal_title：European journal of neurology

authors： Hitomi T,Mezaki T,Tomimoto H,Ikeda A,Shimohama S,Okazaki T,Uchiyama T,Shibasaki H

更新日期：2005-10-01 00:00:00

abstract：:Cortical excitability of the primary motor cortex is altered in patients with Parkinson's disease (PD). Therefore, modulation of cortical excitability by high frequency repetitive transcranial magnetic stimulation (rTMS) of the motor cortex might result in beneficial effects on motor functions in PD. The present study...

journal_title：European journal of neurology

authors： Khedr EM,Farweez HM,Islam H

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with ischaemic stroke (IS) caused by a spontaneous cervical artery dissection (CeAD) worry about an increased risk for stroke in their families. The occurrence of stroke in relatives of patients with CeAD and in those with ischaemic stroke attributable to other (non-CeAD) causes were com...

journal_title：European journal of neurology

authors： Kloss M,Grond-Ginsbach C,Pezzini A,Metso TM,Metso AJ,Debette S,Leys D,Dallongeville J,Caso V,Thijs V,Bersano A,Touzé E,Bonati LH,Tatlisumak T,Arnold ML,Lyrer PA,Engelter ST,Cervical Artery Dissection and Ischemic Stroke

更新日期：2014-08-01 00:00:00

abstract：:Cocaine abuse is a well known cause of cerebrovascular complications. An inflammatory vasculopathy hypothesis has been proposed, but the medical literature has only reported a few pathological confirmations. We report a case with a biopsy demonstrating cerebral inflammatory vascular changes that are associated with co...

journal_title：European journal of neurology

authors： Diez-Tejedor E,Frank A,Gutierrez M,Barreiro P

更新日期：1998-01-01 00:00:00

abstract：:We describe a case of cardiac myxoma whose clinical presentation mimicked that of polyarteritis nodosa. The serum levels of MPO-ANCA and IL-6 were elevated on laboratory investigation and normalized after the removal of the tumor. We suggest that a 'true' vasculitic mechanism contributes to the pathogenesis of pseudov...

journal_title：European journal of neurology

authors： Nishio Y,Ito Y,Iguchi Y,Sato H

更新日期：2005-08-01 00:00:00

abstract：:Among patients who underwent cerebrospinal fluid (CSF) and magnetic resonance imaging (MRI) examination during a 5-year period, we found 18 patients at the multiple sclerosis center of the University of Rome and clinically definite multiple sclerosis, MRI white matter abnormalities, normal CSF examination, a disease d...

journal_title：European journal of neurology

authors： Fieschi C,Gasperini C,Ristori G,Bastianello S,Girmenia F,Leuzzi V,Buttinelli C,Pozzilli C,Rasura M

更新日期：1994-11-01 00:00:00

abstract：:We used 123I-Ioflupane SPECT to study striatal dopamine transporter (DAT) binding in 36 Parkinson's disease (PD) patients with history of severe occupational exposure to hydrocarbons. Data were compared with 38 PD patients without exposure history as well as healthy controls. Both PD cohorts showed significant striata...

journal_title：European journal of neurology

authors： Canesi M,Benti R,Marotta G,Cilia R,Isaias IU,Gerundini P,Pezzoli G,Antonini A

更新日期：2007-03-01 00:00:00

abstract：:Myeloproliferative disorders (MPD) are associated with an increased risk for thrombembolic events. In this study, we examined the prognostic value of transcranial Doppler (TCD) microemboli detection regarding clinical events and correlated TCD findings with results of blood cell counts and platelet flow cytometry to g...

journal_title：European journal of neurology

authors： Weber CA,Matzdorff AC,Gerriets T,Villmow T,Stolz E

更新日期：2007-02-01 00:00:00