Abstract:
BACKGROUND AND PURPOSE:The incidence, underlying physiopathology, features and association with lesion topography of visual hallucinations in acute stroke have scarcely been investigated. METHODS:Patients with a diagnosis of acute stroke (ischaemic or haemorrhagic) in any vascular territory, admitted within 24 h after the onset of symptoms, were consecutively included in the study. Patients with a previous history of psychosis or cognitive impairment were excluded. They and/or their caregivers answered a structured hallucination and sleep questionnaire at admission, within the first 15 days and at the clinical follow-up 3-6 months after discharge. Lesion location (IMAIOS online atlas) and leukoaraiosis (Wahlund scale) were determined by magnetic resonance imaging or computed tomography scan. Subsets of patients also underwent a neuropsychological evaluation (N = 50) and an electroencephalogram (N = 33) before discharge. RESULTS:In all, 77 patients with a mean age of 71 ± 12 years were included of whom 57.1% were men. The incidence of visual hallucinations was 16.7%. These hallucinations were mostly complex, in black and white and self-limited. The appearance of hallucinations was not influenced by age, sex, neuropsychological performance during admission or modified Rankin scale score at discharge. Visual hallucinations were associated with occipital cortex lesions (P = 0.04), and with sleep disturbances during and before admission (P = 0.041 and P = 0.03 respectively). CONCLUSIONS:Visual hallucinations are relatively frequent in patients with acute stroke and they are self-limited. Patients with occipital lesions and sleep disturbances are more likely to suffer them.
journal_name
Eur J Neuroljournal_title
European journal of neurologyauthors
Morenas-Rodríguez E,Camps-Renom P,Pérez-Cordón A,Horta-Barba A,Simón-Talero M,Cortés-Vicente E,Guisado-Alonso D,Vilaplana E,García-Sánchez C,Gironell A,Roig C,Delgado-Mederos R,Martí-Fàbregas Jdoi
10.1111/ene.13278subject
Has Abstractpub_date
2017-05-01 00:00:00pages
734-740issue
5eissn
1351-5101issn
1468-1331journal_volume
24pub_type
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